What makes some people more likely to shiver than others?
Some people just aren't bothered by the cold, no matter how low the temperature dips. And the reason for this may be in a person's genes.
Scientists use high resolution microscopy and computer simulations to create first ever video of DNA movements.
- UK scientists create first ever video of DNA performing dance-like movements.
- The visualization was accomplished using high resolution microscopy and computer simulations.
- The advanced level of detail in the technology may lead to new therapies.
Dancing DNA<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="42fabf2fc9d5f0a790fc05ef5eab46eb"><iframe type="lazy-iframe" data-runner-src="https://www.youtube.com/embed/fJ4JMXkQzoA?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span>
The study found that people who spoke the same language tended to be more closely related despite living far apart.
- Studies focusing on European genetics have found a strong correlation between geography and genetic variation.
- Looking toward India, a new study found a stronger correlation between gene variation and language as well as
- social structure.
- Understanding social and cultural influences can help expand our knowledge of gene flow through human history.
A new kind of mother tongue<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNTU0ODY2MS9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYzODQ4MjEyMH0.Ag7iKSgWxyUn6-v3wbIk7ADkxtbyiuUaodlxjRYmDkk/img.jpg?width=980" id="e0037" class="rm-shortcode" data-rm-shortcode-id="0624bd5ae5c2c18e87d89e6549ef3131" data-rm-shortcode-name="rebelmouse-image" data-width="815" data-height="450" />
A map showing the locations of 33 Indian populations alongside plot graphs showing the relations between sociolinguistic groups and genetic structures.
New dimensions for understanding ancestry<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="b2f6780bd878e2434da8e19bff5481d8"><iframe type="lazy-iframe" data-runner-src="https://www.youtube.com/embed/hu4pjmBTN2Y?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span><p>None of this is to say that geography played no part in the ancestral gene flow of India, nor that social and cultural factors didn't influence genotypes across Europe. They most certainly did. That Nature study, for example, discovered genetic clusters in Switzerland that were language-based. And Europe's geographic distribution may have more to do with historical sociopolitical realities than environmental ones.</p><p>The point of both studies, however, is not to tie our genetic history to land or language, but to understand how genes flowed throughout historical societies.</p><p>"It sheds light on how genetics work in our society," Bose said in the same release. "This is the first model that can take into account social, cultural, environmental and linguistic factors that shape the gene flow of populations. It helps us to understand what factors contribute to the genetic puzzle that is India. It disentangles the puzzle."</p><p>With an improved knowledge of historic gene flow, scientists may be able to further biomedical research to better detect rare genetic variants, assess individual risks to certain diseases, and predict which populations may be more or less susceptible to particular drugs. By opening the avenues we use to understand our genetic history, we can hopefully advance such knowledge and understanding.</p>
Dr. Eric Lander is a pioneer in genomics. What role will he play in the new administration?
- Dr. Lander is a mathematician and geneticist who's best known for his leading role in the Human Genome Project.
- Biden nominated Dr. Lander to head the Office of Science and Technology Policy and also serve as a cabinet-level science adviser, marking the first time the position has been part of the presidential cabinet.
- In an open letter, Biden said it's essential for the U.S. to "refresh and reinvigorate our national science and technology strategy to set us on a strong course for the next 75 years."
Who is Dr. Eric Lander?<p>Born in Brooklyn, New York, Dr. Lander started his academic career as a mathematician, often arriving at high school an hour early to do math. He won multiple awards in mathematics in his teens, including the Mathematical Olympiad in 1974.<br></p><p>Finding mathematics "too monastic" to pursue as a career, he began teaching managerial economics at Harvard Business School. Then, at the <a href="https://www.worldsciencefestival.com/videos/eric-lander-the-genesis-of-genius/" target="_blank">encouragement of his brother</a>, a neurobiologist, Dr. Lander became interested in studying neurobiology and microbiology. This pushed him to his main lifelong pursuit: unraveling the mysteries of the human genome.</p><p>Dr. Lander spent more than a decade as a leader within the Human Genome Project, which provided the world a complete map of all human genes in 2003. In 2004, he founded the Broad Institute, a biomedical and genomic nonprofit research center that partners with M.I.T. and Harvard University.</p>
Credit: Pixabay<p>Broad's <a href="https://www.broadinstitute.org/news-multimedia/basic-q-about-broad-institute" target="_blank">mission</a> is to "fulfill the promise of genomics by creating comprehensive tools for biology and medicine, making them broadly available to the world and applying them to the understanding of human biology and the diagnosis, treatment, and cure of human diseases." The institute aims to diminish diseases by better understanding cellular mechanisms, rather than simply treating symptoms.</p><p>Despite some <a href="https://www.statnews.com/2016/01/25/why-eric-lander-morphed/" target="_blank">minor controversies and patent disputes</a>, Dr. Lander remains a monumental figure in American science, and also previously served as co-chairman of former President Barack Obama's science advisory council.</p>
What will Dr. Lander do in the Biden administration?<p>If confirmed by the Senate, it's not exactly clear what Dr. Lander will do in his role as cabinet science adviser and head of the OSTP. But his primary focus likely won't be COVID-19, considering Biden has already established a task force dedicated to shaping policy and recommendations related to the pandemic.<br></p><p>But Biden revealed some of his expectation in an <a href="https://buildbackbetter.gov/wp-content/uploads/2021/01/OSTP-Appointment.pdf" target="_blank">open letter</a> that posed five questions for the Office of Science and Technology Policy to explore:</p><ol><li>What can we learn from the pandemic about what is possible—or what ought to be possible— to address the widest range of needs related to our public health?</li><li>How can breakthroughs in science and technology create powerful new solutions to address climate change—propelling market-driven change, jump-starting economic growth, improving health, and growing jobs, especially in communities that have been left behind?</li><li>How can the United States ensure that it is the world leader in the technologies and industries of the future that will be critical to our economic prosperity and national security, especially in competition with China?</li><li>How can we guarantee that the fruits of science and technology are fully shared across America and among all Americans?</li><li>How can we ensure the long-term health of science and technology in our nation?</li></ol><p>The president-elect wrote that it's essential to "refresh and reinvigorate our national science and technology strategy to set us on a strong course for the next 75 years," concluding:</p><p style="margin-left: 20px;">"I believe that the answers to these questions will be instrumental in helping our nation embark on a new path in the years ahead—a path of dignity and respect, of prosperity and security, of progress and common purpose. They are big questions, to be sure, but not as big as America's capacity to address them. I look forward to receiving your recommendations—and to working with you, your team, and the broader scientific community to turn them into solutions that ease everyday burdens for the American people, spark new jobs and opportunities, and restore American leadership on the world stage."</p>
Scientists find that an RNA-DNA mix may have created the first life on our planet.
- New study shows that RNA and DNA likely originated together.
- The mixture of the acids are believed to haveproduced Earth's first life forms.
- The molecules were created with the help of a compound available in planet's early days.