New cancer-scanning technology reveals a previously unknown detail of human anatomy.
- Scientists using new scanning technology and hunting for prostate tumors get a surprise.
- Behind the nasopharynx is a set of salivary glands that no one knew about.
- Finding the glands may allow for more complication-free radiation therapies.
PSMA PET/CT technology<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="676e611b970c9b516cace0870447b325"><iframe type="lazy-iframe" data-runner-src="https://www.youtube.com/embed/RHAyoQF09X4?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span><p>PSMA PET/CT is a new combination of <a href="https://www.mayoclinic.org/tests-procedures/pet-scan/about/pac-20385078" target="_blank">PET scans</a> and <a href="https://www.mayoclinic.org/tests-procedures/ct-scan/about/pac-20393675" target="_blank">CT scans</a> that is believed to offer a more reliable means of locating prostate cancer metastasis. A <a href="https://www.cancer.gov/news-events/cancer-currents-blog/2020/prostate-cancer-psma-pet-ct-metastasis" target="_blank" rel="noopener noreferrer">study</a> published last spring suggests it may be the most accurate way to diagnose prostate cancer metastasis than any method previously available.</p><p>Prior to PSMA PET/CT, the primary way to look for metastatic prostate cancer was to image the body using x-ray-based CT scans and to perform bone scans, since bone is where prostate cancer often spreads. CT scans, however, often miss small tumors, and bone scans can generate false positives as a result of other damage or abnormalities that have nothing to do with prostate cancer.</p><p>PSMA PET/CT scans track the travels of an intravenously administered radioactive glucose tracer throughout the body. For hunting down prostate cancer, this tracer contains a molecule that binds to the <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1472940/" target="_blank">PSMA</a> protein that's present in large amounts in prostate tumors. The molecule is linked to a radioisotope, <a href="https://netrf.org/2018/11/13/gallium-68-scan-for-neuroendocrine-tumors/" target="_blank" rel="noopener noreferrer">gallium-68</a> (Ga-68).</p><p>In last spring's research, PSAM PET/CT was shown to be 27 percent more accurate than previous methods at finding metastases (92 percent accuracy as opposed to 65 percent). In addition, it was found to be much less likely to produce false positives, and it was particularly good at detecting tumors far removed from the prostate.</p>
A good kind of avoidance behavior<p>"Radiation therapy can damage the salivary glands," says Vogel, "which may lead to complications. Patients may have trouble eating, swallowing, or speaking, which can be a real burden."</p><p>The researchers looked back through the cases of 723 patients who had undergone radiation treatment, interested in seeing if inadvertent radiation of the tubarial glands was associated with the complications experienced by the patients. It turned out that this <em>was</em> the case: In cases where more radiation had been delivered to this area, patients did indeed report more in the way of complications of the type one would expect when salivary glands are radiated.</p><p>Now that we know the tubarial salivary glands exist, therapists can stay out of their way. Vogel says, "For most patients, it should technically be possible to avoid delivering radiation to this newly discovered location of the salivary gland system in the same way we try to spare known glands."</p><p>He's hopeful that that things may be about to get at least a bit better for cancer patients: "Our next step is to find out how we can best spare these new glands and in which patients. If we can do this, patients may experience less side effects which will benefit their overall quality of life after treatment."</p>
Your health and the health of the planet are not indistinguishable.
- Transitioning to a plant-based diet could help reduce obesity, cardiovascular disease, and type 2 diabetes.
- Humans are destroying entire ecosystems to perpetuate destructive food habits.
- Understanding how to properly transition to a plant-based diet is important for success.
Richard Dawkins: No Civilized Person Accepts Slavery So Why Do We Accept Animal Cruelty? | Big Think<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="c09f23c34faacc8ec55aba054fae9c7c"><iframe type="lazy-iframe" data-runner-src="https://www.youtube.com/embed/_4SnBCPzBl0?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span><h3>Get your hands dirty—in the kitchen</h3><p>Quarantine offered an entire world the opportunity to get into the kitchen and put on a chef's apron. Complaints about "not enough time" are the biggest barriers to preparing home-cooked meals. Of course, pandemic fatigue has resulted in a number of recent chefs ordering out more. That said, this is the perfect time to try your hand at new dishes. With infection rates <a href="https://www.vox.com/coronavirus-covid19/2020/10/11/21511641/covid-19-us-cases-update-testing-deaths-hospitalizations" target="_blank">increasing across the country</a>, stocking up on seasonal vegetables is a great idea. </p><p>Simple seasonal ways to begin your plant-based exploration include <a href="https://nomnompaleo.com/post/11136213353/roasted-kabocha-squash" target="_blank" rel="noopener noreferrer">roasted kabocha squash</a>, <a href="https://www.delicious.com.au/recipes/no-chop-pumpkin-soup/seblnp2r?r=recipes/collections/autumnrecipes&c=f3bf723a-05a7-487d-bd4b-5bc8af042ca9/autumn%20recipes%20you%27ll%20fall%20in%20love%20with" target="_blank" rel="noopener noreferrer">Bombay potatoes</a>, and <a href="https://www.delicious.com.au/recipes/no-chop-pumpkin-soup/seblnp2r?r=recipes/collections/autumnrecipes&c=f3bf723a-05a7-487d-bd4b-5bc8af042ca9/autumn%20recipes%20you%27ll%20fall%20in%20love%20with" target="_blank" rel="noopener noreferrer">no-chop pumpkin soup</a>. If you're feeling a bit more adventurous, <a href="https://www.thecuriouschickpea.com/masoor-dal-tadka/" target="_blank" rel="noopener noreferrer">Masoor Dal Tadka</a> will keep you warm into the winter months. A delicious <a href="https://www.delish.com/cooking/recipe-ideas/a23362341/sweet-potato-salad-recipe/" target="_blank" rel="noopener noreferrer">sweet potato salad</a> will never fail you. This <a href="https://www.buzzfeed.com/hannahloewentheil/easy-meatless-monday-recipes" target="_blank">round-up of 25 vegetarian recipes</a> will keep you busy for a few months (or a month if you're ambitious). </p><h3>Educate yourself on the benefits</h3><p>Education is essential for beginning any endeavor. Weeding through propaganda and bunk science to find credible evidence of any diet is difficult, though many experts agree that for individual and societal health, a plant-based diet is key. </p><p>Even vegetarianism has its pitfalls. For example, <a href="https://michaelpollan.com/books/cooked/" target="_blank">one-fifth of all calories</a> consumed by Americans come from nutritionally-worthless white flour. If you're eating processed bread every day, you're missing out on the benefits of a rich and varied diet. </p><p>Many of the "<a href="https://www.who.int/chp/chronic_disease_report/media/Factsheet4.pdf?ua=1" target="_blank">diseases of affluence</a>," such as cardiovascular and obesity-related ailments, originate with a poor diet (and lack of exercise). Meat has been an essential component of the human diet throughout our evolution. Today, we eat too much of it—and too much of it is produced in factory farms. Transitioning to a plant-based diet could help cut down on carbon emissions and the aforementioned diseases. </p><p>Plants are full of valuable phytochemicals and antioxidants that support a <a href="https://www.mdanderson.org/publications/focused-on-health/5-benefits-of-a-plant-based-diet.h20-1592991.html" target="_blank" rel="noopener noreferrer">strong immune system</a>. A (non-processed) plant-based diet reduces inflammation and offers plenty of fiber. It has been shown to reduce your risk of diabetes, stroke, and heart diseases. Those are all great reasons to transition. </p><h3>Begin your journey with a single step</h3><p>Going cold turkey rarely works for addicts. The same is true of diets. If you're interested in a plant-based diet, try to eat veg every other day for a few weeks. Notice how your body reacts on days you eat this way compared to other days. Gradually phase out meat products. Attempt meat-free weekdays and see if your craving for meat persists on the weekend. Try using meat as a garnish instead of the main course. </p><p>More importantly, have a replacement plan. Dropping all meat products to consume frozen dinners isn't the best course of action. Filling your cart with bags of foods you've never eaten before will overwhelm you. Prepare meals as you taper off of meat; arm yourself with a broad knowledge of healthy plants and vegetables. At some point, you might forget what you've been missing. </p>
Photo: anaumenko / Adobe Stock<h3>Start with foods you already love</h3><p>The good news is that you likely have a number of plant-based side and main dishes that you love. Transitioning into a new diet requires a certain level of enjoyment. Otherwise, you're going to loathe eating, and eating should bring some level of satisfaction. </p><p>Try a one-to-one ratio to begin. On one night, cook a meal you love. Then try something completely new the next night. Follow that up with old faithful. This way, you constantly have new dishes to look forward to yet don't get stuck in thinking you have to be creative every single day. You'll likely find some winners and decide not to repeat other dishes. Regardless, you'll have a broader menu to work from. </p><h3>Avoid ingredients you can't pronounce</h3><p>The produce section of your grocery store provides almost everything you need to survive. You can likely pronounce every ingredient in this section. There's a vast difference between food and foodstuffs. Plenty of plant-based companies offer too much of the latter. Potato chips are technically vegetarian, and some use simple ingredients, yet it's easy to fill your cart with foodstuffs. The health benefits of this are not only negligible but potentially dangerous. </p><p>Qi Sun, an assistant professor of nutrition at the Harvard T.H. Chan School of Public Health, <a href="https://www.webmd.com/diet/obesity/news/20191104/are-there-health-downsides-to-vegetarian-diets" target="_blank">explains</a>. "If you eat a vegan diet, but eat a lot of french fries, refined carbs like white bread, white rice, that's not healthy." He suggests "emphasizing fruits and vegetables. Not fruit juice but whole food. And nuts."</p><h3>Utilize the wisdom of the internet—but don't get indoctrinated</h3><p>There's a lot of terrible advice—and worse, propaganda—on the internet. While you likely don't want to eat eggs every day, they're not "toxic," as one popular documentary claims. Eggs are <a href="https://www.bbcgoodfood.com/howto/guide/ingredient-focus-eggs" target="_blank">one of the best</a> low-cost, high-value foods around. </p><p>Read websites like <a href="https://www.everydayhealth.com/diet-nutrition/scientific-benefits-following-plant-based-diet/" target="_blank">Everyday Health</a>, which uses clear language, like "may improve" and "may decrease," with links to credible studies. This way you follow the going science without becoming fanatical about a particular diet or being disappointed if it turns out the research doesn't hold up. Good science evolves with evidence. And right now, the evidence points to more vegetables in our diets. </p><p>--</p><p><em>Stay in touch with Derek on <a href="http://www.twitter.com/derekberes" target="_blank">Twitter</a> and <a href="https://www.facebook.com/DerekBeresdotcom" target="_blank" rel="noopener noreferrer">Facebook</a>. His new book is</em> "<em><a href="https://www.amazon.com/gp/product/B08KRVMP2M?pf_rd_r=MDJW43337675SZ0X00FH&pf_rd_p=edaba0ee-c2fe-4124-9f5d-b31d6b1bfbee" target="_blank" rel="noopener noreferrer">Hero's Dose: The Case For Psychedelics in Ritual and Therapy</a>."</em></p>
The sudden prevalence of an artery in the forearm is evidence that we're still very much a work in progress.
- Australian scientists see signs of accelerating human evolution.
- Exhibit A is the rapid rise in the prevalence of the median artery in adults.
- Other emerging traits, like shorter baby jaws, support their finding.
The rise of the median artery<p>The study was authored by scientists from <a href="https://www.flinders.edu.au" target="_blank">Flinders University</a> and the <a href="https://www.adelaide.edu.au/front/international.html?adobe_mc_sdid=SDID%3D6F3F7FE9AFD60DD6-7758ADFFE05FB639|MCORGID%3DBA023B045D5A83160A495E49%40AdobeOrg|TS%3D1602523779&adobe_mc_ref=https%3A%2F%2Fwww.google.com%2F" target="_blank">University of Adelaide</a> in South Australia. It's published in the <a href="https://onlinelibrary.wiley.com/doi/10.1111/joa.13224" target="_blank">Journal of Anatomy</a>.<br></p><p>The median artery supplies blood to a fetus' forearm in the womb during early gestation. It <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327784/" target="_blank">typically</a> atrophies and is replaced by the radial and ulna arteries before birth. Few adults have historically had all three arteries — median, radial, and ulna — but this has been changing. </p><p>The study's senior author <a href="https://www.adelaide.edu.au/directory/maciej.henneberg" target="_blank">Maciej Henneberg</a> <a href="https://news.flinders.edu.au/blog/2020/10/08/forearm-artery-reveals-human-evolution-continues/" target="_blank">says</a>, "This is micro evolution in modern humans and the median artery is a perfect example of how we're still evolving because people born more recently have a higher prevalence of this artery when compared to humans from previous generations."</p><p>The phenomenon was first noticed in the 18th century, and a study of the artery's persistence was conducted in 1995. The more recent study extends that work, finding that the occurrence of the artery trio is accelerating.</p><p>"The prevalence was around 10% in people born in the mid-1880s compared to 30% in those born in the late 20th century," says lead author <a href="https://medicalsciences.med.unsw.edu.au/people/dr-teghan-lucas" target="_blank" rel="noopener noreferrer">Teghan Lucas</a>, "so that's a significant increase in a fairly short period of time, when it comes to evolution."</p><p>Why this is occurring isn't clear. "This increase could have resulted from mutations of genes involved in median artery development or health problems in mothers during pregnancy, or both actually," says Lucas.</p><p>However, she says, one thing is clear: "If this trend continues, a majority of people will have median artery of the forearm by 2100."</p><span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="1ad42f2dbdf44fb8ce1468e6bb53bab3"><iframe type="lazy-iframe" data-runner-src="https://www.youtube.com/embed/zIb9mymN80o?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span>
(Fore)armed with insight<p>The researchers tracked the presence the median artery in cadavers. They examined the 78 upper limbs obtained from Australians who died between 2015 and 2016. The deceased were from 51 to 101 years of age at death. In 26 of the limbs, the median artery was present.</p><p>Says Henneberg, "We've collected all the data published in anatomical literature and continued to dissect cadavers donated for studies in Adelaide, and we found about one third of Australians have the median artery in their forearm and everyone will have it by the end of the century if this process continues."</p><p>The scientists' conclusion is that we're evolving more quickly now than at any point in the last 250 years of study.</p>
The young man died nearly 2,000 years ago in the volcanic eruption that buried Pompeii.
- A team of researchers in Italy discovered the intact brain cells of a young man who died in the Mount Vesuvius eruption in A.D. 79.
- The brain's cell structure was visible to researchers (who used an electron microscope) in a glassy, black material found inside the man's skull.
- The material was likely the victim's brain preserved through the process of vitrification in which the intense heat followed by rapid cooling turned the organ to glass.
Discovery of cells<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNDUwNTc3Ny9vcmlnaW4ucG5nIiwiZXhwaXJlc19hdCI6MTY1NzkxOTE3Nn0.P40yPfGHp1jlqrALyP2BXokaKnS1u0ThXdmsbOuRrtw/img.png?width=1245&coordinates=0%2C78%2C0%2C0&height=700" id="ba6e0" class="rm-shortcode" data-rm-shortcode-id="72ff4c56563712e6e7a89df6207cebf1" data-rm-shortcode-name="rebelmouse-image" />
Electron microscope image of brain axons.
Credit: PLOS ONE<p>Now, subsequent research has described how the researchers, using an electron microscope, discovered cells in the vitrified brain. According to Petrone they were "incredibly well preserved with a resolution that is impossible to find anywhere else." Additionally, the team used another method called energy-dispersive X-ray spectroscopy to determine the chemical compounds of the glassy material. The sample was rich in carbon and oxygen, which indicates that it was organic. The researchers compared those ancient proteins to a database of proteins found in the human brain, and found that all of the discovered proteins are indeed present in human brain tissue.</p> <p>Additionally, Petrone and his team suspect they also discovered vitrified nerve cells in the ancient victim's spinal cord and cerebellum based on the position of the sample in the mind of the skull and the concentration of the proteins. </p>
Future research<p>These impeccable preservations of brain tissue are unprecedented and will undoubtedly open the door to new and exciting research opportunities on these ancient people and civilizations that weren't possible until now.</p> <p>The Italian research team will continue to study the remains to learn more about the vitrification process, including the precise temperatures the victims were exposed to and the cooling rate of the ash. They also, according to Petrone, want to analyze proteins from the remains and their related genes. </p>
An accident left this musician with one arm. Now he is helping create future tech for others with disabilities.
- Meet the world's first bionic drummer. Rock musician Jason Barnes lost his arm in a terrible accident... and then he became the fastest drummer in the world.
- With the help of Gil Weinberg, a Georgia Tech professor and inventor of musical robots, the pair utilized electromyography and ultrasound technology to break musical records.
- Weinberg and Barnes hope to perfect the technology so that it can one day be used to help other people with disabilities realize that "they're not only not disabled, they're actually super-able."