Nutrisystem is a smarter weight-loss program that users enjoy.
- The societal and economic consequences of obesity cannot be ignored.
- The economic impact is up to $190 billion every year in America.
- Americans spend up to $2.5 billion each year on popular weight-loss programs.
Credit: Nutrisystem<h3>The economics of obesity</h3><p>The obesity crisis in America has profoundly changed the health of our nation. Two-thirds of American adults are now overweight or obese. Excess body weight creates numerous health problems, such as increased risk for heart disease, hypertension, cancer, sleep apnea, stroke, and type 2 diabetes. Tragically, the steep rise in obesity rates can, in large part, be traced back to the surge in processed foods made with filler ingredients, questionable preservatives, and excessive sugars. </p><p>That's part of what makes losing weight so difficult. Supermarket shelves are stocked with processed foods. A whopping 74 percent of packaged foods contain added sugars, which are conveniently disguised under 61 different names, including dextrose, maltose, and treacle. You shouldn't have to play detective every time you go to the grocery store. </p><p>Obesity has real-world consequences. Every year, up to $6.38 billion is lost in productivity costs due to obesity-related absenteeism. That number only accounts for people taking off of work. Overall, obesity-related costs in America are estimated to be $147 billion every year. One <a href="https://www.hsph.harvard.edu/obesity-prevention-source/obesity-consequences/economic/" target="_blank">study</a> shows that cost was $190 billion in 2005. </p><p>Overweight citizens are also more likely to suffer from poor mental health. The combination of poor self-image, social stigma, lack of exercise, and biological issues due to obesity increase the likelihood that someone will be anxious or depressed. This creates a crippling feedback loop: diets high in sugars and carbohydrates, which are fueling the rise in obesity, are <a href="https://bigthink.com/21st-century-spirituality/your-diet-might-be-causing-anxiety-and-depression" target="_self">also linked</a> to poor mental health. </p><p>Many people want a solution that works. In 2014, Americans spent roughly $2.5 billion on commercial or proprietary weight loss programs. As a society, we pay the price of obesity in the form of work absenteeism, inflated health care costs, and mental health issues, and we pay trying to solve it. Finding a solution to this problem is of utmost importance. </p>
A fairly old idea, but a really good one, is about to hit the store shelves.
- The idea of growing food from CO2 dates back to NASA 50 years ago.
- Two companies are bringing high-quality, CO2-derived protein to market.
- CO2-based foods provide an environmentally benign way of producing the protein we need to live.
The basic idea<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNTQ0NTM3Ny9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYxOTc4NzE1MX0.qxFjO6GkVVEjS_VEKy4pIkrmv-gknDbBgTHourWFUcc/img.jpg?width=980" id="20397" class="rm-shortcode" data-rm-shortcode-id="fa52d13cbf404456d0a5be77ff2e091e" data-rm-shortcode-name="rebelmouse-image" data-width="1089" data-height="898" />
Credit: Big Think<p> The basic mechanism for deriving food from CO<sup>2</sup> involves a fairly simple closed-loop system that executes a process over and over in a cyclical manner, producing edible matter along the way. In space, astronauts produce carbon dioxide when they breathe, which is then captured by microbes, which then convert it into a carbon-rich material. The astronauts eat the material, breathe out more CO<sup>2</sup>, and on and on. On Earth, the CO<sup>2</sup> is captured from the atmosphere. </p>
Drawing first breath<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNTQ0NTM3NS9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTY0NDQyNjAwMH0.3b4FuXhLwAqGtXzFu2dw8Gec6phKp3bxkajLOJKFOYE/img.jpg?width=980" id="03d4b" class="rm-shortcode" data-rm-shortcode-id="a5131ef8090c05af83989905de39c53d" data-rm-shortcode-name="rebelmouse-image" data-width="1000" data-height="780" />
Credit: NASA<p> NASA's investigation into using CO<sup>2</sup> for food production began with a 1966 report written by R. B. Jagow and R. S. Thomas and published by Ames Research Center. The nine-chapter report was called "<a href="https://ntrs.nasa.gov/citations/19670025254" target="_blank">The Closed Life-Support System</a>." Each chapter contained a proposal for growing food on long missions. </p><p> Chapter 8, written by J. F. Foster and J. H. Litchfield of the Battelle Memorial Institute in Columbus, Ohio, proposed a system that utilized a hydrogen-fixing bacteria, <em><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC247306/" target="_blank">Hydrogenomonas</a></em>—NASA had been experimenting with the bacteria for several years at that point—and recycled CO<sup>2</sup> in a compact, low-power, closed-loop system. The system would be able to produce edible cell matter in way that "should then be possible to maintain continuous cultures at high efficiencies for very long periods of time." </p><p> At the time, extended missions that would benefit from such a system were off in the future. </p><p> In 2019, and with its eye toward upcoming Mars missions, NASA returned to the idea, sponsoring the <a href="https://www.nasa.gov/directorates/spacetech/centennial_challenges/co2challenge/challenge-announced.html" target="_blank">CO2 Conversion Challenge</a>, "seeking novel ways to convert carbon dioxide into useful compounds." Phase 1 of the contest invited proposals for processes that could "convert carbon dioxide into glucose in order to eventually create sugar-based fuel, food, medicines, adhesives and other products." </p><p> In May 2109, NASA announced the <a href="https://www.nasa.gov/spacetech/centennial_challenges/co2challenge/winning-teams-design-systems-to-convert-carbon-dioxide-into-something-sweet.html" target="_blank">winners</a> of Phase 1. The space agency concluded acceptance of <a href="https://www.co2conversionchallenge.org/#about" target="_blank">Phase 2</a> entries on December 4, 2020.</p>
Approaching the Finnish line<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNTQ0NTM2Mi9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTY0MTkyNDYzNH0.02upErPyJQO5YvKEmk-Hqrve4Prg_5cZHMaXBFCAbOQ/img.jpg?width=980" id="e593a" class="rm-shortcode" data-rm-shortcode-id="e2d8de8068bcd9f497f284d2fafc7b9c" data-rm-shortcode-name="rebelmouse-image" data-width="1400" data-height="930" />
Credit: Solar Foods<p> We've <a href="https://bigthink.com/technology-innovation/protein-from-air?rebelltitem=1#rebelltitem1" target="_self">written previously</a> about <a href="https://solarfoods.fi" target="_blank">Solar Foods</a>, a company backed by the Finnish government who <a href="https://solarfoods.fi/our-news/business-finland-greenlights-solar-foods-e8-6m-project/" target="_blank">recently invested</a> €4.3 million to help complete the company's €8.6 million commercialization of their nutrient-rich CO<sup>2</sup>-based protein powder, <a href="https://solarfoods.fi/solein/" target="_blank">Solein</a>. The company anticipates Solein will provide protein to some 400 million meals by 2025, and has so far developed 20 different food products from it. </p>
In the air tonight<blockquote class="instagram-media" data-instgrm-captioned data-instgrm-permalink="https://www.instagram.com/p/B5GXIMzgBRA/?utm_source=ig_embed&utm_campaign=loading" data-instgrm-version="13" style=" background:#FFF; border:0; border-radius:3px; box-shadow:0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width:540px; min-width:326px; padding:0; width:99.375%; width:-webkit-calc(100% - 2px); width:calc(100% - 2px);"><div style="padding:16px;"> <a href="https://www.instagram.com/p/B5GXIMzgBRA/?utm_source=ig_embed&utm_campaign=loading" style=" background:#FFFFFF; line-height:0; padding:0 0; text-align:center; text-decoration:none; width:100%;" target="_blank"> <div style=" display: flex; flex-direction: row; align-items: center;"> <div style="background-color: #F4F4F4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;"></div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center;"> <div style=" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;"></div> <div style=" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;"></div></div></div><div style="padding: 19% 0;"></div> <div style="display:block; height:50px; margin:0 auto 12px; width:50px;"><svg width="50px" height="50px" viewBox="0 0 60 60" version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink"><g stroke="none" stroke-width="1" fill="none" fill-rule="evenodd"><g transform="translate(-511.000000, -20.000000)" fill="#000000"><g><path d="M556.869,30.41 C554.814,30.41 553.148,32.076 553.148,34.131 C553.148,36.186 554.814,37.852 556.869,37.852 C558.924,37.852 560.59,36.186 560.59,34.131 C560.59,32.076 558.924,30.41 556.869,30.41 M541,60.657 C535.114,60.657 530.342,55.887 530.342,50 C530.342,44.114 535.114,39.342 541,39.342 C546.887,39.342 551.658,44.114 551.658,50 C551.658,55.887 546.887,60.657 541,60.657 M541,33.886 C532.1,33.886 524.886,41.1 524.886,50 C524.886,58.899 532.1,66.113 541,66.113 C549.9,66.113 557.115,58.899 557.115,50 C557.115,41.1 549.9,33.886 541,33.886 M565.378,62.101 C565.244,65.022 564.756,66.606 564.346,67.663 C563.803,69.06 563.154,70.057 562.106,71.106 C561.058,72.155 560.06,72.803 558.662,73.347 C557.607,73.757 556.021,74.244 553.102,74.378 C549.944,74.521 548.997,74.552 541,74.552 C533.003,74.552 532.056,74.521 528.898,74.378 C525.979,74.244 524.393,73.757 523.338,73.347 C521.94,72.803 520.942,72.155 519.894,71.106 C518.846,70.057 518.197,69.06 517.654,67.663 C517.244,66.606 516.755,65.022 516.623,62.101 C516.479,58.943 516.448,57.996 516.448,50 C516.448,42.003 516.479,41.056 516.623,37.899 C516.755,34.978 517.244,33.391 517.654,32.338 C518.197,30.938 518.846,29.942 519.894,28.894 C520.942,27.846 521.94,27.196 523.338,26.654 C524.393,26.244 525.979,25.756 528.898,25.623 C532.057,25.479 533.004,25.448 541,25.448 C548.997,25.448 549.943,25.479 553.102,25.623 C556.021,25.756 557.607,26.244 558.662,26.654 C560.06,27.196 561.058,27.846 562.106,28.894 C563.154,29.942 563.803,30.938 564.346,32.338 C564.756,33.391 565.244,34.978 565.378,37.899 C565.522,41.056 565.552,42.003 565.552,50 C565.552,57.996 565.522,58.943 565.378,62.101 M570.82,37.631 C570.674,34.438 570.167,32.258 569.425,30.349 C568.659,28.377 567.633,26.702 565.965,25.035 C564.297,23.368 562.623,22.342 560.652,21.575 C558.743,20.834 556.562,20.326 553.369,20.18 C550.169,20.033 549.148,20 541,20 C532.853,20 531.831,20.033 528.631,20.18 C525.438,20.326 523.257,20.834 521.349,21.575 C519.376,22.342 517.703,23.368 516.035,25.035 C514.368,26.702 513.342,28.377 512.574,30.349 C511.834,32.258 511.326,34.438 511.181,37.631 C511.035,40.831 511,41.851 511,50 C511,58.147 511.035,59.17 511.181,62.369 C511.326,65.562 511.834,67.743 512.574,69.651 C513.342,71.625 514.368,73.296 516.035,74.965 C517.703,76.634 519.376,77.658 521.349,78.425 C523.257,79.167 525.438,79.673 528.631,79.82 C531.831,79.965 532.853,80.001 541,80.001 C549.148,80.001 550.169,79.965 553.369,79.82 C556.562,79.673 558.743,79.167 560.652,78.425 C562.623,77.658 564.297,76.634 565.965,74.965 C567.633,73.296 568.659,71.625 569.425,69.651 C570.167,67.743 570.674,65.562 570.82,62.369 C570.966,59.17 571,58.147 571,50 C571,41.851 570.966,40.831 570.82,37.631"></path></g></g></g></svg></div><div style="padding-top: 8px;"> <div style=" color:#3897f0; font-family:Arial,sans-serif; font-size:14px; font-style:normal; font-weight:550; line-height:18px;"> View this post on Instagram</div></div><div style="padding: 12.5% 0;"></div> <div style="display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;"><div> <div style="background-color: #F4F4F4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);"></div> <div style="background-color: #F4F4F4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;"></div> <div style="background-color: #F4F4F4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);"></div></div><div style="margin-left: 8px;"> <div style=" background-color: #F4F4F4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;"></div> <div style=" width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; transform: translateX(16px) translateY(-4px) rotate(30deg)"></div></div><div style="margin-left: auto;"> <div style=" width: 0px; border-top: 8px solid #F4F4F4; border-right: 8px solid transparent; transform: translateY(16px);"></div> <div style=" background-color: #F4F4F4; flex-grow: 0; height: 12px; width: 16px; transform: translateY(-4px);"></div> <div style=" width: 0; height: 0; border-top: 8px solid #F4F4F4; border-left: 8px solid transparent; transform: translateY(-4px) translateX(8px);"></div></div></div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center; margin-bottom: 24px;"> <div style=" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 224px;"></div> <div style=" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; width: 144px;"></div></div></a><p style=" color:#c9c8cd; font-family:Arial,sans-serif; font-size:14px; line-height:17px; margin-bottom:0; margin-top:8px; overflow:hidden; padding:8px 0 7px; text-align:center; text-overflow:ellipsis; white-space:nowrap;"><a href="https://www.instagram.com/p/B5GXIMzgBRA/?utm_source=ig_embed&utm_campaign=loading" style=" color:#c9c8cd; font-family:Arial,sans-serif; font-size:14px; font-style:normal; font-weight:normal; line-height:17px; text-decoration:none;" target="_blank">A post shared by Air Protein (@airprotein)</a></p></div></blockquote> <script async src="//www.instagram.com/embed.js"></script><p> Another player, <a href="https://www.airprotein.com" target="_blank">Air Protein</a>, is based in California's Bay Area and is also bringing to market their own CO<sup>2</sup> protein named after the company. The company <a href="https://www.prnewswire.com/news-releases/air-protein-introduces-the-worlds-first-air-based-food-300955972.html" target="_blank">describes</a> it as a "nutrient-rich protein with the same amino acid profile as an animal protein and packed with crucial B vitamins, which are often deficient in a vegan diet." </p><p> The company recently <a href="https://www.greenqueen.com.hk/air-protein-bags-us32m-in-series-a-to-commercialise-climate-friendly-meat/" target="_blank">secured $32 million</a> in venture-capital funding. </p><p> Although Air Protein is actually flour—like Solein—the company is positioning Air Protein as offering "the first air-based meat," while Solein was announced first, and there's <a href="https://www.afr.com/life-and-luxury/food-and-wine/company-that-makes-meat-out-of-air-attracts-big-backers-20210108-p56sk0" target="_blank" rel="noopener noreferrer">no public timetable</a> yet for the arrival of Air Protein products on store shelves. In any event, non-animal "meats" are a <a href="https://bigthink.com/technology-innovation/whopper" target="_self">hot market</a> these days with the success of Beyond Burger and Impossible Foods cruelty-free meat substitutes. </p>
Striking oil<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNTQ0NTM2Ny9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTY1MzE3NjA3NH0.1o05KthbzT9JokT7-0UzWDq4MiLIfXJIGfPddhLNKqk/img.jpg?width=980" id="a45ef" class="rm-shortcode" data-rm-shortcode-id="143316dcc3691fcce024e83a6cbaca3f" data-rm-shortcode-name="rebelmouse-image" data-width="1440" data-height="959" />
Deforestation for palm oil
Credit: whitcomberd/Adobe Stock<p> Though Air Protein's promotional materials emphasize meat substitutes that will be derived from their flour, a <a href="https://youtu.be/c8WMM_PUOj0" target="_blank">TED Talk</a> by company co-founder Lisa Dyson reveals another Air Protein product that could arguably have an even greater impact by potentially eliminating the need for palm oil and the deforestation it requires — their CO<sup>2</sup> process can produce oils.</p><p><span></span>The company has already created a citrus-like oil that can be used for fragrances, flavoring, as a biodegradable cleaner, and "even as a jet fuel." Perhaps more excitingly, the company has made another oil that's similar to palm oil. Since palm trees are the <a href="https://www.ran.org/palm_oil_fact_sheet" target="_blank">crop most responsible</a> for the decimation of the world's rain forests, an environmentally benign replacement for it would be a very big deal. Dyson also notes that their oils could substitute morally problematic coconut oil, whose harvesting has lately been reported to often involve the abuse of macaque monkeys.</p>
Putting carbon dioxide to work<p> We know we have too much of the stuff, so finding a way of utilizing at least some CO<sup>2</sup> to create foods and other products that reduce the need for destructive commercial practices is a solid win for humankind. Harkening back to its NASA origins, Dyson notes in her talk that Earth, too, is sort of a self-contained spaceship, albeit a big one. Finding new ways to productively reuse what it has to offer clearly benefits us all. </p>
Porcine gene edits may allow such transplants without rejection.
- A company called Revivicor has received clearance from the FDA to use their genetically modified pigs for medical use or as food.
- The pigs lack genes for alpha-gal sugar, which human bodies reject.
- Revivicor anticipates the first human transplant trials as early as this year.
Waiting lists<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNTI2NTc2OC9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTY3Mjk1Nzk2M30.4ZzZpCgUitKf03AYJeAwIbFCMoaeuEUKnbOexWuar1Q/img.jpg?width=980" id="0349f" class="rm-shortcode" data-rm-shortcode-id="ac2e62bb595a203a6ce81bb646e6e618" data-rm-shortcode-name="rebelmouse-image" data-width="1440" data-height="821" />
Credit: Talaj/Adobe Stock/Big Think<p>The U.S. Health Resources and Services Administration <a href="https://www.organdonor.gov/statistics-stories/statistics.html" target="_blank">says</a> that 109,000 Americans are currently waiting for organ transplants. Seventeen people die each day while waiting, and every nine minutes a new name goes on the waiting list.</p><p>Companies such as Revivicor are hoping to meet this need with <a href="https://web.stanford.edu/dept/HPST/transplant/html/frequently_asked_questions.html" target="_blank">xenotransplants</a>, in which organs from non-human species are transplanted into humans. Scientists have been seeking a way to perform successful xenotransplantation for decades—a newborn referred to publicly as "Baby Fae" rejected a transplanted baboon heart as far back as 1984.</p><p>Ayares says his company is "right on the cusp" of overcoming such rejection issues, anticipating their first transplants may occur in 2021 or 2022.</p><p>Animal tissue may also find use in the formulation of medications.</p>
Rejection<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNTI2NTg1OS9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYzMzA2Mjc0OH0.pN1W_Vupa5LpYUoq9tHBTQBqRPpdZw6HneRsKmG0vD4/img.jpg?width=980" id="e2d4d" class="rm-shortcode" data-rm-shortcode-id="6675d842b366bec68fc612fbeb380930" data-rm-shortcode-name="rebelmouse-image" data-width="1440" data-height="617" />
Credit: ustas /Adobe Stock<p>The rejection problem stems from the human body's immune system expelling cells from other animals as foreign substances. (Rejection can also be an issue with human-to-human transplants.)</p><p>In 2003, Revivicor began development of GalSafe pigs by removing a gene that appears on the surface of porcine cells, and that produces a sugar called "alpha-gal." It's believed that alpha-gal sugar is the agent that causes the most acute rejections experienced with heart and kidney transplants.</p><p>Alpha-gal is also implicated in a meat food-allergy that occurs after a person is bitten by a Lone Star tick that leaves alpha-gal sugar behind in its victims' skin. Over time, the individual develops an allergy to pork, red meat, and lamb. Revivicor's Gal Pigs may one day be available to such people as non-allergenic pork.</p><p>Revivicor's manipulation of pig genes to support xenotransplantation compatibility doesn't end with eliminating alpha-gal sugar. Today's GalPig carries a total of 10 different genomic modifications—four pig genes have been turned off and six human genes have been introduced.</p>
Tests so far<p>The company, working with the National Institutes of Health, says that they managed to avoid rejection of pig hearts transplanted into baboons for six years, though these didn't replace the animals' own, original hearts. Rather, the pig hearts were transplanted into the abdomens of the baboons simply to assess rejection. Ayares also says GalPig kidneys survived in monkeys for over six months, though it's unclear if they were functioning as kidneys or simply implanted.</p><p>For human trials, Revivicor plans to begin with kidney transplants before attempting heart replacements. They expect to perform these early trials with people awaiting human transplants. XenoTherapeutics of Boston is already testing GalPig skin transplants as a temporary measure for burn victims as their own skin regenerates.</p><p>Other companies are also exploring porcine genetic modifications for xenotransplants, including eGenesis in Boston and its partner Qihan Biotech in Zhejiang, China, who are using CRISPR to perform gene edits.</p>
An archaeologist considers the history and biology of what defines a taste of home.
Agriculture is responsible for a quarter of greenhouse emissions, but who pays for these environmental costs?
- A new study shows that food products fail to include their environmental costs in their price.
- If meat products included the cost of their carbon footprints, their prices would more than double.
- Policies to factor in these costs could change food consumption in ways that lower carbon emissions.