from the world's big
Legalized marijuana linked to lower opioid abuse; death rates
A new study analyzed more than 1.5 billion opioid prescriptions over eight years.
- A new study analyzed over 1.5 billion opioid prescriptions between 2011 and 2018.
- Researchers discovered opioid prescription reductions of 11.8 percent and 4.2 percent in states that passed recreational and medical cannabis laws.
- The U.S. government needs to reschedule cannabis because researchers believe it has therapeutic value.
Pain is important. It informs us of problems that need attention. Our biological pain system can go awry: some people don't feel any pain while others experience chronic pain with no evident cause. There's mental pain, which from a physiological perspective is no different than physical pain, which is why aspirin is sometimes used to treat emotional duress.
Our relationship to pain seems to become more problematic as societies acclimate to higher levels of comfort. The habit of pill-popping to counter any negative biological reaction is so engrained that we rarely question their chemical composition or long-term consequences. The shift from aspirin for minor aches and pains to the surge in opioid consumption signals a culture unwilling to deal with even the slightest discomfort.
Of course, there are good reasons for some opioid usage, but the scourge of addiction has hit us hard. Families across the nation have lost loved ones. Indeed, over a two-decade period, more than 700,000 Americans died from drug overdoses — the bulk of them opioid-related.
As I've written about previously, over a one-year period I was given access to 120 Oxycodone tablets for surgeries due to cancer and a meniscus tear. Both times I took one and discarded the bottle. Instead, I turned to cannabis for pain management, which was not only more effective but also did not leave me susceptible to addiction.
Could Cannabis Be A Solution To The Opioid Crisis?
I'm not alone. While there have been numerous reports about the benefits of cannabis for pain management instead of opioids, a new study, published on Dec. 14 in Journal of Health Economics, analyzed over 1.5 billion opioid prescriptions given between 2011 and 2018. The researchers confirmed the hype: states that legalize marijuana see sizable drops in opioid consumption.
Opioid prescriptions quadrupled between 2000–2015. As with the mental health industry and SSRIs scripts, pain management in recent years has relied on a money-making band-aid instead of actually treating the cause. It's much easier to write a prescription and send the patient on their way than to root out a diagnosis and plot out an extensive plan to help them overcome it. This trend also revitalized heroin consumption, which became a cheaper solution when pill bottles could not be found.
Enter the burgeoning field of cannabis science. As the researchers write,
"One policy option that has the potential to reduce opioid prescriptions and opioid-related deaths is the passage of cannabis access laws. These state laws facilitate access to cannabis by removing state legal barriers — though possession of cannabis remains illegal under federal law."
The researchers, from the University of Alabama School of Law and Vanderbilt University, list numerous studies confirming cannabis's efficacy in pain management, again calling into question why it remains listed as a Schedule 1 substance. Regardless, society is moving quicker than legislation. People want to feel better, not become beholden to a drug whose efficacy is clinically worse than marijuana.
Marijuana activists hold up a 51-foot inflatable joint during a rally at the U.S. Capitol to call on Congress pass cannabis reform legislation on Tuesday, Oct. 8, 2019.
Photo by Caroline Brehman/CQ-Roll Call, Inc via Getty Images
The team analyzed roughly 90 percent of all opioid scripts written over an eight-year period. They compare regional data with the passage of both Recreational Cannabis Laws (RCL) and Medical Cannabis Laws (MCL), discovering prescription reductions of 11.8 percent and 4.2 percent, respectively. When people are given the option, they are more likely to go with the proven track record of marijuana. The team concludes,
"The evidence reported here presents the most accurate picture of the effect of cannabis access laws on prescription opioid use to date and can therefore inform the ongoing state and national debates over the legality of cannabis as well as other policy options to combat the opioid epidemic."
Pain affects aging populations more, and so the researchers looked into RCLs and MCLs affecting Medicare and Medicaid rates. If all states passed MCLs in 2014, Medicaid savings would have been over $1 billion. They also found, as has been widely reported, states that pass MCLs and RCLs experience lower mortality rates from opioid overdoses.
There is an ongoing debate about whether you can become addicted to cannabis or just dependent, yet one thing is clear: marijuana is not nearly as dangerous as opioids. Pain management is a discussion the medical industry needs to have with their patients. Avoiding pain at any cost is not worth it. For those suffering from pain, there is at least one viable solution. Our government needs to recognize this fact and change the scheduling, while doctors have to honor science instead of lobbying and marketing efforts by pharmaceutical companies.
What would it be like to experience the 4th dimension?
Physicists have understood at least theoretically, that there may be higher dimensions, besides our normal three. The first clue came in 1905 when Einstein developed his theory of special relativity. Of course, by dimensions we’re talking about length, width, and height. Generally speaking, when we talk about a fourth dimension, it’s considered space-time. But here, physicists mean a spatial dimension beyond the normal three, not a parallel universe, as such dimensions are mistaken for in popular sci-fi shows.
If machines develop consciousness, or if we manage to give it to them, the human-robot dynamic will forever be different.
- Does AI—and, more specifically, conscious AI—deserve moral rights? In this thought exploration, evolutionary biologist Richard Dawkins, ethics and tech professor Joanna Bryson, philosopher and cognitive scientist Susan Schneider, physicist Max Tegmark, philosopher Peter Singer, and bioethicist Glenn Cohen all weigh in on the question of AI rights.
- Given the grave tragedy of slavery throughout human history, philosophers and technologists must answer this question ahead of technological development to avoid humanity creating a slave class of conscious beings.
- One potential safeguard against that? Regulation. Once we define the context in which AI requires rights, the simplest solution may be to not build that thing.
Duke University researchers might have solved a half-century old problem.
- Duke University researchers created a hydrogel that appears to be as strong and flexible as human cartilage.
- The blend of three polymers provides enough flexibility and durability to mimic the knee.
- The next step is to test this hydrogel in sheep; human use can take at least three years.
Duke researchers have developed the first gel-based synthetic cartilage with the strength of the real thing. A quarter-sized disc of the material can withstand the weight of a 100-pound kettlebell without tearing or losing its shape.
Photo: Feichen Yang.<p>That's the word from a team in the Department of Chemistry and Department of Mechanical Engineering and Materials Science at Duke University. Their <a href="https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.202003451" target="_blank">new paper</a>, published in the journal,<em> Advanced Functional Materials</em>, details this exciting evolution of this frustrating joint.<br></p><p>Researchers have sought materials strong and versatile enough to repair a knee since at least the seventies. This new hydrogel, comprised of three polymers, might be it. When two of the polymers are stretched, a third keeps the entire structure intact. When pulled 100,000 times, the cartilage held up as well as materials used in bone implants. The team also rubbed the hydrogel against natural cartilage a million times and found it to be as wear-resistant as the real thing. </p><p>The hydrogel has the appearance of Jell-O and is comprised of 60 percent water. Co-author, Feichen Yang, <a href="https://today.duke.edu/2020/06/lab-first-cartilage-mimicking-gel-strong-enough-knees" target="_blank">says</a> this network of polymers is particularly durable: "Only this combination of all three components is both flexible and stiff and therefore strong." </p><p> As with any new material, a lot of testing must be conducted. They don't foresee this hydrogel being implanted into human bodies for at least three years. The next step is to test it out in sheep. </p><p>Still, this is an exciting step forward in the rehabilitation of one of our trickiest joints. Given the potential reward, the wait is worth it. </p><p><span></span>--</p><p><em>Stay in touch with Derek on <a href="http://www.twitter.com/derekberes" target="_blank">Twitter</a>, <a href="https://www.facebook.com/DerekBeresdotcom" target="_blank">Facebook</a> and <a href="https://derekberes.substack.com/" target="_blank">Substack</a>. His next book is</em> "<em>Hero's Dose: The Case For Psychedelics in Ritual and Therapy."</em></p>
An algorithm may allow doctors to assess PTSD candidates for early intervention after traumatic ER visits.