DNA Is Multibillion-Year-Old Software
Nature invented software billions of years before we did. “The origin of life is really the origin of software,” says Gregory Chaitin (inventor of mathematical metabiology). Life requires what software does. It is fundamentally algorithmic. And its complexity needs better thinking tools.
Jag Bhalla is an entrepreneur, inventor and writer. His current project is Errors We Live By, a series of short exoteric essays exposing errors in the big ideas running our lives, details at www.errorsweliveby.com. His last book was I'm Not Hanging Noodles On Your Ears, a surreptitious science gift book from National Geographic Books, details at www.hangingnoodles.com. That explains his twitter handle @hangingnoodles.
Nature invented software billions of years before we did. “The origin of life is really the origin of software,” says Gregory Chaitin. Life requires what software does (it’s foundationally algorithmic).
2. Alan Turing described modern software in 1936, inspiring John Von Neumann to connect software to biology. Before DNA was understood, Von Neumann saw that self-reproducing automata needed software. We now know DNA stores information; it's a biochemical version of Turning’s software tape, but more generally: All that lives must process information. Biology's basic building blocks are processes that make decisions.
3. Casting life as software provides many technomorphic insights (and mis-analogies), but let’s consider just its informational complexity. Do life’s patterns fit the tools of simpler sciences, like physics? How useful are experiments? Algebra? Statistics?
4. The logic of life is more complex than the inanimate sciences need. The deep structure of life’s interactions are algorithmic (loosely algorithms = logic with if-then-else controls). Can physics-friendly algebra capture life’s biochemical computations?
5. Describing its “pernicious influence” on science, Jack Schwartz says, mathematics succeeds in only “the simplest of situations” or when “rare good fortune makes [a] complex situation hinge upon a few dominant simple factors.”
6. Physics has low “causal density” — a great Jim Manzi coinage. Nothing in physics chooses. Or changes how it chooses. A few simple factors dominate, operating on properties that generally combine in simple ways. Its parameters are independent. Its algebra-friendly patterns generalize well (its equations suit stable categories and equilibrium states).
7. Higher-causal-density domains mean harder experiments (many hard-to-control factors that often can’t be varied independently). Fields like medicine can partly counter their complexity by randomized trials, but reliable generalization requires biological “uniformity of response.”
8. Social sciences have even higher causal densities, so “generalizing from even properly randomized experiments” is “hazardous,” Manzi says. “Omitted variable bias” in human systems is “massive." Randomization ≠ representativeness of results is guaranteed.
9. Complexity economist Brian Arthur says science’s pattern-grasping toolbox is becoming “more algorithmic ... and less equation-based.” But the nascent algorithmic era hasn’t had its Newton yet.
10. With studies in high-causal-density fields, always consider how representative data is, and ponder if uniform or stable responses are plausible. Human systems are often highly variable; our behaviors aren’t homogenous; they can change types; they’re often not in equilibrium.
11. Bad examples: Malcolm Gladwell puts entertainment first (again) by asserting that “the easiest way to raise people’s scores” is to make a test less readable (n = 40 study, later debunked). Also succumbing to unwarranted extrapolation, leading data-explainer Ezra Klein said, "Cutting-edge research shows that the more information partisans get, the deeper their disagreements.” That study neither represents all kinds of information, nor is a uniform response likely (in fact, assuming that would be ridiculous). Such rash generalizations = far from spotless record.
Mismatched causal density and thinking tools creates errors. Entire fields are built on assuming such (mismatched) metaphors and methods.
(Hat tip to Bryan Atkins @postgenetic for pointer to Brian Arthur).
Further reading: Microsoft Plans to Have a DNA-Based Computer by 2020
Illustration by Julia Suits, The New Yorker Cartoonist & author of The Extraordinary Catalog of Peculiar Inventions.
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Calling all big thinkers!
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- The report comes in the wake of other explicitly anti-socialist sentiments expressed by the Trump administration.
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