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Why highly intelligent people suffer from more mental and physical disorders
Your brain's heightened sensitivity can make you perceptive and creative. But it's a double-edged sword, researchers find.

People with high IQ are considered to have an advantage in many domains. They are predicted to have higher educational attainment, better jobs, and a higher income level. Yet, it turns out that a high IQ is also associated with various mental and immunological diseases like depression, bipolar disorder, anxiety, ADHD as well as allergies, asthma, and immune disorders. Why is that? A new paper published in the journal Intelligence reviews the literature and explores the mechanisms that possibly underlie this connection.
The study authors compared data taken from 3,715 members of the American Mensa Society (people who have scored in the top 2% of intelligent tests) to data from national surveys in order to examine the prevalence of several disorders in those with higher intelligence compared to the average population.
The results showed that highly intelligent people are 20% more likely to be diagnosed with autism spectrum disorder (ASD), 80% more likely to be diagnosed with ADHD, 83% more likely to be diagnosed with anxiety, and 182% more likely to develop at least one mood disorder.
When it comes to physiological diseases, people with high cognitive abilities are 213% more likely to have environmental allergies, 108% more likely to have asthma, and 84% more likely to have an autoimmune disease.
Credit: Journal of Intelligence / High intelligence: A risk factor for psychological and physiological overexcitabilities
The researchers turned to the field of psychoneuroimmunology (PNI) to look for some of the answers. PNI examines how the chronic stress accumulated as a response to environmental factors influences the communication between the brain and the immune system.
The researchers point out that highly intelligent people have tendencies for “intellectual overexcitabilites" and a hyper-reactivity of the central nervous system. On the one hand, this gives people with high IQ heightened awareness that helps their creative and artistic work. In fact, the field of cognitive ability recognizes one aspect of highly intelligent people to be “a broader and deeper capacity to comprehend their surroundings."

This hyper-reactivity, however, can also lead to deeper depressions and poor mental health. This turns out to be particularly true for poets, novelists and people with high verbal intelligence. Their intense emotional response to the environment increases tendencies for rumination and worry, both of which predict depression and anxiety disorders.
Heightened psychological responses can affect immunity, write the researchers. People with overexcitabilites may have strong reactions to seemingly harmless external stimuli like an annoying clothing tag or a sound. This reaction may turn into low level chronic stress and launch an inappropriate immune response.
When the body believes it is in danger (regardless of whether it is an objectively real one like a toxin or an imagined one like an annoying sound), it launches a cascade of physiological responses that include a myriad of hormones, neurotransmitters and signaling molecules. When these processes are chronically activated, they can alter the body and the brain, dysregulate immune function and lead to conditions like asthma, allergies and autoimmune diseases.
The scientific literature has confirmed the association between gifted children and an increased rate of allergies and asthma. One study shows that 44% of those with an IQ over 160 suffered from allergies compared to 20% of age-matched peers. Тhe exploratory study done by the authors of this latest paper further supports that connection.
Based on their findings and previous studies the researchers have termed this phenomenon the hyper brain / hyper body theory of integration, explaining that:
The overexcitabilities specific to those with high intelligence may put these individuals at risk for hypersensitivity to internal and/or external environmental events. The rumination and worry that accompanies this heightened awareness may contribute to a chronic pattern of fight, flight, or freeze responses which then launch a cascade of immunological events. [...] Ideally, immune regulation is an optimal balance of pro- and anti-inflammatory response. It should zero in on inflammation with force and then immediately return to a calm state. In those with the overexcitabilities previously discussed, including in those with ASD, this system appears to fail to achieve a balance and thus inflammatory signals create a state of chronic activation.
Credit: Journal of Intelligence / High intelligence: A risk factor for psychological and physiological overexcitabilities
The authors conclude that it is important to further study the relationship between high intelligence (particularly the top 2%) and illness, especially in order to demonstrate causation and further bring to light the negative aspects of having a high IQ. As they say, “this gift can either be a catalyst for empowerment and self-actualization or it can be a predictor of dysregulation and debilitation" and in order to serve this group, it is important “to acknowledge the rumbles of thunder that follow in the wake of their brilliance."

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There are 5 eras in the universe's lifecycle. Right now, we're in the second era.
Astronomers find these five chapters to be a handy way of conceiving the universe's incredibly long lifespan.
Image based on logarithmic maps of the Universe put together by Princeton University researchers, and images produced by NASA based on observations made by their telescopes and roving spacecraft
- We're in the middle, or thereabouts, of the universe's Stelliferous era.
- If you think there's a lot going on out there now, the first era's drama makes things these days look pretty calm.
- Scientists attempt to understand the past and present by bringing together the last couple of centuries' major schools of thought.
The 5 eras of the universe
<p>There are many ways to consider and discuss the past, present, and future of the universe, but one in particular has caught the fancy of many astronomers. First published in 1999 in their book <a href="https://amzn.to/2wFQLiL" target="_blank"><em>The Five Ages of the Universe: Inside the Physics of Eternity</em></a>, <a href="https://en.wikipedia.org/wiki/Fred_Adams" target="_blank">Fred Adams</a> and <a href="https://en.wikipedia.org/wiki/Gregory_P._Laughlin" target="_blank">Gregory Laughlin</a> divided the universe's life story into five eras:</p><ul><li>Primordial era</li><li>Stellferous era</li><li>Degenerate era</li><li>Black Hole Era</li><li>Dark era</li></ul><p>The book was last updated according to current scientific understandings in 2013.</p><p>It's worth noting that not everyone is a subscriber to the book's structure. Popular astrophysics writer <a href="https://www.forbes.com/sites/ethansiegel/#30921c93683e" target="_blank">Ethan C. Siegel</a>, for example, published an article on <a href="https://www.forbes.com/sites/startswithabang/2019/07/26/we-have-already-entered-the-sixth-and-final-era-of-our-universe/#7072d52d4e5d" target="_blank"><em>Medium</em></a> last June called "We Have Already Entered The Sixth And Final Era Of Our Universe." Nonetheless, many astronomers find the quintet a useful way of discuss such an extraordinarily vast amount of time.</p>The Primordial era
<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yMjkwMTEyMi9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYyNjEzMjY1OX0.PRpvAoa99qwsDNprDme9tBWDim6mS7Mjx6IwF60fSN8/img.jpg?width=980" id="db4eb" class="rm-shortcode" data-rm-shortcode-id="0e568b0cc12ed624bb8d7e5ff45882bd" data-rm-shortcode-name="rebelmouse-image" data-width="1440" data-height="1049" />Image source: Sagittarius Production/Shutterstock
<p> This is where the universe begins, though what came before it and where it came from are certainly still up for discussion. It begins at the Big Bang about 13.8 billion years ago. </p><p> For the first little, and we mean <em>very</em> little, bit of time, spacetime and the laws of physics are thought not yet to have existed. That weird, unknowable interval is the <a href="https://www.universeadventure.org/eras/era1-plankepoch.htm" target="_blank">Planck Epoch</a> that lasted for 10<sup>-44</sup> seconds, or 10 million of a trillion of a trillion of a trillionth of a second. Much of what we currently believe about the Planck Epoch eras is theoretical, based largely on a hybrid of general-relativity and quantum theories called quantum gravity. And it's all subject to revision. </p><p> That having been said, within a second after the Big Bang finished Big Banging, inflation began, a sudden ballooning of the universe into 100 trillion trillion times its original size. </p><p> Within minutes, the plasma began cooling, and subatomic particles began to form and stick together. In the 20 minutes after the Big Bang, atoms started forming in the super-hot, fusion-fired universe. Cooling proceeded apace, leaving us with a universe containing mostly 75% hydrogen and 25% helium, similar to that we see in the Sun today. Electrons gobbled up photons, leaving the universe opaque. </p><p> About 380,000 years after the Big Bang, the universe had cooled enough that the first stable atoms capable of surviving began forming. With electrons thus occupied in atoms, photons were released as the background glow that astronomers detect today as cosmic background radiation. </p><p> Inflation is believed to have happened due to the remarkable overall consistency astronomers measure in cosmic background radiation. Astronomer <a href="https://www.youtube.com/watch?v=IGCVTSQw7WU" target="_blank">Phil Plait</a> suggests that inflation was like pulling on a bedsheet, suddenly pulling the universe's energy smooth. The smaller irregularities that survived eventually enlarged, pooling in denser areas of energy that served as seeds for star formation—their gravity pulled in dark matter and matter that eventually coalesced into the first stars. </p>The Stelliferous era
<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yMjkwMTEzNy9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYxMjA0OTcwMn0.GVCCFbBSsPdA1kciHivFfWlegOfKfXUfEtFKEF3otQg/img.jpg?width=980" id="bc650" class="rm-shortcode" data-rm-shortcode-id="c8f86bf160ecdea6b330f818447393cd" data-rm-shortcode-name="rebelmouse-image" data-width="481" data-height="720" />Image source: Casey Horner/unsplash
<p>The era we know, the age of stars, in which most matter existing in the universe takes the form of stars and galaxies during this active period. </p><p>A star is formed when a gas pocket becomes denser and denser until it, and matter nearby, collapse in on itself, producing enough heat to trigger nuclear fusion in its core, the source of most of the universe's energy now. The first stars were immense, eventually exploding as supernovas, forming many more, smaller stars. These coalesced, thanks to gravity, into galaxies.</p><p>One axiom of the Stelliferous era is that the bigger the star, the more quickly it burns through its energy, and then dies, typically in just a couple of million years. Smaller stars that consume energy more slowly stay active longer. In any event, stars — and galaxies — are coming and going all the time in this era, burning out and colliding.</p><p>Scientists predict that our Milky Way galaxy, for example, will crash into and combine with the neighboring Andromeda galaxy in about 4 billion years to form a new one astronomers are calling the Milkomeda galaxy.</p><p>Our solar system may actually survive that merger, amazingly, but don't get too complacent. About a billion years later, the Sun will start running out of hydrogen and begin enlarging into its red giant phase, eventually subsuming Earth and its companions, before shrining down to a white dwarf star.</p>The Degenerate era
<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yMjkwMTE1MS9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYxNTk3NDQyN30.gy4__ALBQrdbdm-byW5gQoaGNvFTuxP5KLYxEMBImNc/img.jpg?width=980" id="77f72" class="rm-shortcode" data-rm-shortcode-id="08bb56ea9fde2cee02d63ed472d79ca3" data-rm-shortcode-name="rebelmouse-image" data-width="1440" data-height="810" />Image source: Diego Barucco/Shutterstock/Big Think
<p>Next up is the Degenerate era, which will begin about 1 quintillion years after the Big Bang, and last until 1 duodecillion after it. This is the period during which the remains of stars we see today will dominate the universe. Were we to look up — we'll assuredly be outta here long before then — we'd see a much darker sky with just a handful of dim pinpoints of light remaining: <a href="https://earthsky.org/space/evaporating-giant-exoplanet-white-dwarf-star" target="_blank">white dwarfs</a>, <a href="https://earthsky.org/space/new-observations-where-stars-end-and-brown-dwarfs-begin" target="_blank">brown dwarfs</a>, and <a href="https://earthsky.org/astronomy-essentials/definition-what-is-a-neutron-star" target="_blank">neutron stars</a>. These"degenerate stars" are much cooler and less light-emitting than what we see up there now. Occasionally, star corpses will pair off into orbital death spirals that result in a brief flash of energy as they collide, and their combined mass may become low-wattage stars that will last for a little while in cosmic-timescale terms. But mostly the skies will be be bereft of light in the visible spectrum.</p><p>During this era, small brown dwarfs will wind up holding most of the available hydrogen, and black holes will grow and grow and grow, fed on stellar remains. With so little hydrogen around for the formation of new stars, the universe will grow duller and duller, colder and colder.</p><p>And then the protons, having been around since the beginning of the universe will start dying off, dissolving matter, leaving behind a universe of subatomic particles, unclaimed radiation…and black holes.</p>The Black Hole era
<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yMjkwMTE2MS9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYzMjE0OTQ2MX0.ifwOQJgU0uItiSRg9z8IxFD9jmfXlfrw6Jc1y-22FuQ/img.jpg?width=980" id="103ea" class="rm-shortcode" data-rm-shortcode-id="f0e6a71dacf95ee780dd7a1eadde288d" data-rm-shortcode-name="rebelmouse-image" data-width="1400" data-height="787" />Image source: Vadim Sadovski/Shutterstock/Big Think
<p> For a considerable length of time, black holes will dominate the universe, pulling in what mass and energy still remain. </p><p> Eventually, though, black holes evaporate, albeit super-slowly, leaking small bits of their contents as they do. Plait estimates that a small black hole 50 times the mass of the sun would take about 10<sup>68</sup> years to dissipate. A massive one? A 1 followed by 92 zeros. </p><p> When a black hole finally drips to its last drop, a small pop of light occurs letting out some of the only remaining energy in the universe. At that point, at 10<sup>92</sup>, the universe will be pretty much history, containing only low-energy, very weak subatomic particles and photons. </p>The Dark Era
<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yMjkwMTE5NC9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTY0Mzg5OTEyMH0.AwiPRGJlGIcQjjSoRLi6V3g5klRYtxQJIpHFgZdZkuo/img.jpg?width=980" id="60c77" class="rm-shortcode" data-rm-shortcode-id="7a857fb7f0d85cf4a248dbb3350a6e1c" data-rm-shortcode-name="rebelmouse-image" data-width="1440" data-height="810" />Image source: Big Think
<p>We can sum this up pretty easily. Lights out. Forever.</p>Dark energy: The apocalyptic wild card of the universe
Dr. Katie Mack explains what dark energy is and two ways it could one day destroy the universe.
- The universe is expanding faster and faster. Whether this acceleration will end in a Big Rip or will reverse and contract into a Big Crunch is not yet understood, and neither is the invisible force causing that expansion: dark energy.
- Physicist Dr. Katie Mack explains the difference between dark matter, dark energy, and phantom dark energy, and shares what scientists think the mysterious force is, its effect on space, and how, billions of years from now, it could cause peak cosmic destruction.
- The Big Rip seems more probable than a Big Crunch at this point in time, but scientists still have much to learn before they can determine the ultimate fate of the universe. "If we figure out what [dark energy is] doing, if we figure out what it's made of, how it's going to change in the future, then we will have a much better idea for how the universe will end," says Mack.
Astrophysicists find unique "hot Jupiter" planet without clouds
A unique exoplanet without clouds or haze was found by astrophysicists from Harvard and Smithsonian.
Illustration of WASP-62b, the Jupiter-like planet without clouds or haze in its atmosphere.
- Astronomers from Harvard and Smithsonian find a very rare "hot Jupiter" exoplanet without clouds or haze.
- Such planets were formed differently from others and offer unique research opportunities.
- Only one other such exoplanet was found previously.
Munazza Alam – a graduate student at the Center for Astrophysics | Harvard & Smithsonian.
Credit: Jackie Faherty
Jupiter's Colorful Cloud Bands Studied by Spacecraft
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