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Why a lab-grown, plant-based Burger King Whopper is cause for excitement
Beefless meat enters the mainstream.
- Burger King is testing its first major foray into the field of beefless patties.
- On top of plant-based meats, cellular agriculture — or "cell-ag" — can also yield animal-free patties.
- A new report lists 90 reasons that cell-ag holds a lot of promise.
Burger King has just announced they're testing a new version of their Whopper that's completely free of actual beef, in 59 locations around St. Louis. Not that even Whopper devotees can tell the difference, according to reports. It's called the "Impossible Whopper." (Impossible Burgers and Beyond Meat burgers are already available in grocery stores.)
The food chain isn't the first to offer a lab-grown, plant-based patty option, but Burger King's announcement is a very big deal. While the new Whopper's currently in testing, if it becomes available at its 7,200 restaurants, it means millions of consumers will be introduced to an animal cruelty-free meat option that's every bit as satisfying as traditional fare.
For those concerned about their health, climate change, and animal rights, there might be no turning back.
The Impossible Taste Test | Impossible Whopper
Burger King conducted an experiment to evaluate how well Whopper fans know their beloved Whopper.
Welcome to cellular agriculture
While the Impossible Whopper and other alternative "meats" are a beginning, researchers are also looking further down the road to animal-product alternatives constructed at the cellular level that don't even require plant matter as current options do.
Enter "Cellular Agriculture," or "Cell-ag," a new form of food and clothing production that results in food and clothing products indistinguishable from traditional offerings without the necessity of raising — and killing — a live animal, or even a plant. A report explaining what this could mean has just been released. It's called 90 Reasons to Consider Cellular Agriculture.
As author Kristopher Gasteratos notes in the report's introduction, modern animal husbandry is no longer the industry we've known for thousands of years: "While animal products have been incredibly positive for society over multiple generations, today they are proving more destructive than beneficial with the rise of factory farming." Gasteratos is a researcher at Harvard and founder of the Cellular Agriculture Society.
The report's cumulative effect is overwhelming: 90 good reasons is a lot of good reasons. They're arranged in categories: Health, Environment, Human & Animal Rights, and Business and Economics. Here's a brief summary of each.
Image source: Cellular Agriculture Society
The health case
This section contains, among other things, a list of the things we won't get from lab-grown cell-ag foods, including:
- pathogens such as Salmonella and E. Coli
- fecal contamination
- meat and seafood growth hormones
- mad-cow disease prions
- swine and avian flu, and other illnesses
- plastic particles in "seafood"
- mercury in "seafood"
- animal-production antibiotics that accelerate the development of resistant superbugs
Cell-ag also looks to promote greater food production stability and predictability, and can scale to help feed the planet's growing population. Their contaminant-free growing environment gives cell-ag foods a longer shelf life. Critical shortages can be more efficiently addresses after disasters, and famines can be avoided, and geographically independent production solves current supply issues in areas that struggle to import food.
Image source: Brooke Becker / Shutterstock
The environment case
We know that the extensive land-use requirements of animal-based products are among the main drivers of climate change. For some animals, it's an issue of grazing land. For others, such as seafood, it's processing.
Here's how much less land Gasteratos estimates we'll use after switching to cell-ag:
- cattle — 99%
- dairy — 97%
- poultry — 66%
- pigs — 82%
- seafood — 55%
- land overall — 80%
It's much the same story with water use:
- cattle — 98%
- dairy — 99.6%
- poultry — 92%
- pigs — -95%
- seafood — 86%
- water overall — 94%
Here's the reduction in greenhouse gases (GHG) an industrial switch to cell-ag may produce:
- cattle — 96%
- dairy — 65%
- poultry — 74%
- pigs — 85%
- seafood — 59%
- GHG overall — 76%
General environmental benefits
Production and food and clothing animals is dirty work, and there's a long list of pollutants it generates, all of which may be avoided by cell-ag: land and ocean animal waste, production chemicals that create dead zones, and plastic pollution from the fishing industry among them.
In addition to resulting in less deforestation, cell-ag promises less ocean habitat destruction from bottom-trawling, and an overall reduced need for energy in food production.
Cattle farming is a key driver of deforestation in Brazil. Rio Branco, Acre, Brazil. Image source: CIFOR
The animal and human rights case
Well, obviously, cell-ag could bring about the end of killing countless cows, pigs, chickens, and seafood and so on. Not to mention the elimination of the often inhumane conditions, particularly in factory farming, in which production animals spend their short lives.
You might not think at first there's much of a human-rights issue in food production, but there are several, and they're serious. Factory farming and food processing operations can be brutal places to work. Factory farm workers, says the report, are at higher risk for amputations, tannery workers are regularly exposed to carcinogenic chemicals, and the seafood industry exploits cheap and slave labor for catching fish.
In the U.S., there's also environmental racism that cell-ag could end, with food-production facilities exposing poorer — often black — neighborhoods to dangerous runoff and sprayed chemicals.
Pig farm fecal waste being sent airborne on the edge of a residential community
Pig farm fecal waste being sent airborne on the edge of a residential community
The business and economics case
In addition to the dawning of a new industry with lots of new jobs, the rise of cell-ag has other positive economic benefits as well.
A food supply that's independent of weather conditions cannot only be a boon in the climate-change era, but the same foods — being grown indoors — can become available in any area, regardless of local climate.
Because cell-ag is more predictable and controllable than traditional agriculture, it affords not only greater quality consistency, but also greater financial predictability. Cell-ag can reduce the uncertainties faced today by today's growers, and help avoid the need for the many subsidies and bailouts currently required for both over- and under-production, saving taxpayers money. Even growers' neighbors benefit once farming stops lowering the value of their own homes.
Cruelty-free products may also become valued premium products for which premium prices may be asked.
Image source: Aaron Weiss / Shutterstock
Would you like a better life with that Whopper?
Gasteratos is undoubtedly personally invested in cell-ag, and so the report paints a decidedly rosy picture of its benefits. Even so, you wouldn't think a new burger lunch option could make such a drastic difference in the world. 90 Reasons to Consider Cellular Agriculture may convince you it can.
Update Tuesday, April 16, 2019: The original headline for this post referred to the Impossible Whopper as being "lab-grown," which is technically true. The plant-based burger was developed in a lab. However, a number of our readers felt the headline suggested the burger was the product of cell-ag, which it is not. To avoid any further confusion, we've changed the headline.
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Scientists used CT scanning and 3D-printing technology to re-create the voice of Nesyamun, an ancient Egyptian priest.
- Scientists printed a 3D replica of the vocal tract of Nesyamun, an Egyptian priest whose mummified corpse has been on display in the UK for two centuries.
- With the help of an electronic device, the reproduced voice is able to "speak" a vowel noise.
- The team behind the "Voices of the Past" project suggest reproducing ancient voices could make museum experiences more dynamic.
Scientists have reproduced the voice of an ancient Egyptian priest by creating a 3D-printed replica of his mummified vocal tract.
An international and interdisciplinary team, led by David Howard, a professor of electronic engineering at Royal Holloway, used computed tomography (CT) scanning technology to measure the dimensions of the vocal tract of Nesyamun, a mummy that's spent about two centuries on display at Leeds City Museum in the United Kingdom.
The team then used those measurements to 3D-print an artificial vocal tract, through which they produced sounds using a peculiar electronic device called the Vocal Tract Organ. (You can check it out here.)
"The Vocal Tract Organ, a first in its own right, provided the inspiration for doing this," Howard told CNET.
Nesyamun, whose priestly duties included chanting and singing the daily liturgy, can once again "speak" — at least, in the form of a vowel noise that sounds something like a cross between the English pronunciation of the vowels in "bed" and "bad."
Of course, the new "voice" of Nesyamun is an approximation, and given the lack of actual recordings of his voice, and the degeneration of his body over millennia, it's impossible to know just how accurate it is. But the researchers suggested that their "Voice from the Past" project offers a chance for people to "engage with the past in completely new and innovative ways."
Howard et al.
"While this approach has wide implications for heritage management/museum display, its relevance conforms exactly to the ancient Egyptians' fundamental belief that 'to speak the name of the dead is to make them live again'," they wrote in a paper published in Nature Scientific Reports. "Given Nesyamun's stated desire to have his voice heard in the afterlife in order to live forever, the fulfilment of his beliefs through the synthesis of his vocal function allows us to make direct contact with ancient Egypt by listening to a sound from a vocal tract that has not been heard for over 3000 years, preserved through mummification and now restored through this new technique."
Connecting modern people with history
It's not the first time scientists have "re-created" an ancient human's voice. In 2016, for example, Italian researchers used software to reconstruct the voice of Ötzi, an iceman who was discovered in 1991 and is thought to have died more than 5,000 years ago. But the "Voices of the Past" project is different, the researchers note, because Nesyamun's mummified corpse is especially well preserved.
"It was particularly suited, given its age and preservation [of its soft tissues], which is unusual," Howard told Live Science.
As to whether Nesyamun's reconstructed voice will ever be able to speak complete sentences, Howard told The Associated Press, that it's "something that is being worked on, so it will be possible one day."
John Schofield, an archaeologist at the University of York, said that reproducing voices from history can make museum experiences "more multidimensional."
"There is nothing more personal than someone's voice," he told The Associated Press. "So we think that hearing a voice from so long ago will be an unforgettable experience, making heritage places like Karnak, Nesyamun's temple, come alive."
Ancient corridors below the French capital have served as its ossuary, playground, brewery, and perhaps soon, air conditioning.
- People have been digging up limestone and gypsum from below Paris since Roman times.
- They left behind a vast network of corridors and galleries, since reused for many purposes — most famously, the Catacombs.
- Soon, the ancient labyrinth may find a new lease of life, providing a sustainable form of air conditioning.
Ancient mining areas below Paris for limestone (red) and gypsum (green).Credit: Émile Gérards (1859–1920) / Public domain
"If you're brave enough to try, you might be able to catch a train from UnLondon to Parisn't, or No York, or Helsunki, or Lost Angeles, or Sans Francisco, or Hong Gone, or Romeless."
China Miéville's fantasy novel Un Lun Dun is set in an eerie mirror version of London. In it, he hints that other cities have similar doubles. On the list that he offhandedly rattles off, Paris stands out. Because the City of Light really does have a twisted sister. Below Paris Overground is Paris Underground, the City of Darkness.
Most people will have heard of the Catacombs of Paris: subterranean charnel houses for the bones of around six million dead Parisians. They are one of the French capital's most famous tourist attractions – and undoubtedly its grisliest.
But they constitute only a small fragment of what the locals themselves call les carrières de Paris ("the mines of Paris"), a collection of tunnels and galleries up to 300 km (185 miles) long, most of which are off-limits to the public, yet eagerly explored by so-called cataphiles.
The Grand Réseau Sud ("Great Southern Network") takes up around 200 km beneath the 5th, 6th, 14th, and 15th arrondissements (administrative districts), all south of the river Seine. Smaller networks run beneath the 12th, 13th, and 16th arrondissements. How did they get there?
Paris stone and plaster of Paris
It all starts with geology. Sediments left behind by ancient seas created large deposits of limestone in the south of the city, mostly south of the Seine; and gypsum in the north, particularly in the hills of Montmartre and Ménilmontant. Highly sought after as building materials, both have been mined since Roman times.
The limestone is also known as Lutetian limestone (Lutetia is the Latin name for ancient Paris) or simply "Paris stone." It has been used for many famous Paris landmarks, including the Louvre and the grand buildings erected during Georges-Eugène Haussmann's large-scale remodelling of the city in the mid-19th century. The stone's warm, yellowish color provides visual unity and a bright elegance to the city.
The fine-powdered gypsum of northern Paris, used for making quick-setting plaster, was so famed for its quality that "plaster of Paris" is still used as a term of distinction. However, as gypsum is very soluble in water, the underground cavities left by its extraction were extremely vulnerable to collapse.
Like living on top of a rotting tooth: subsidence starts far below the surface, but it can destroy your house.Credit : Delavanne Avocats
In previous centuries, a road would occasionally open up to swallow a chariot, or even a whole house would disappear down a sinkhole. In 1778, a catastrophic subsidence in Ménilmontant killed seven. That's why the Montmartre gypsum quarries were dynamited rather than just left as they were. The remaining gypsum caves were to be filled up with concrete.
The official body governing Paris down below is the Inspection Générale des Carrières (IGC), founded in the late 1770s by King Louis XVI. The IGC was tasked with mapping and, where needed, propping up the current and ancient (and sometimes forgotten) mining corridors and galleries hiding beneath Paris.
A delightful hiding place
Also around that time, the dead of Paris were getting in the way of the living. At the end of the 18th century, their final destination consisted of about 200 small cemeteries, scattered throughout the city — all bursting at the seams, so to speak. There was no room to bury the newly dead, and the previously departed were fouling up both the water and air around their respective churchyards.
Something radical had to happen. And it did. From 1785 until 1814, the smaller cemeteries were emptied of their bones, which were transported with full funerary pomp to their final resting place in the ancient limestone quarries at Tombe-Issoire. Three large and modern cemeteries were opened to receive the remains of subsequent generations of Parisians: Montparnasse, Père-Lachaise, and Passy.
The six million dead Parisians in the Catacombs, from all corners of the capital and across many centuries, together form the world's largest necropolis — their now anonymized skulls and bones methodically stacked, occasionally into whimsical patterns. The Catacombs are fashioned into a memorial to the brevity of life. The message above the entrance reads: Arrête! C'est ici l'empire de la Mort. ("Halt! This is the empire of Death.")
That has not stopped the Catacombs, accessible via a side door to a classicist building on the Avenue du Colonel Henri Rol-Tanguy, making just about every Top 20 list of things to see in Paris.
An underground economy
However, while the Catacombs certainly are the most famous part of the centuries-old network beneath Paris, and in non-pandemic times draw thousands of tourists each day, they constitute just 1.7 km (1 mile) of the 300-km (185-mile) tunneling total.
Subterranean Paris wasn't just used for mining and storing dead people. In the 17th century, Carthusian monks converted the ancient quarries under their monastery into distilleries for the green or yellow liqueur that still carries their name, chartreuse.
Because the mines generally keep a constant cool temperature of around 15° C (60° F), they were also ideal for brewing beer, as happened on a large scale from the end of the 17th century until well into the 20th century. Several caves were dug especially for establishing breweries, and not just because of the ambient temperature: going underground allowed brewers to remain close to their customers without having to pay a premium for real estate up top.
Overview of the Paris Catacombs.Credit: Inspection Générale des Carrières, 1857 / Public domain.
At the end of the 19th century, the underground breweries of the 14th arrondissement alone produced more than a million hectoliters (22 million gallons) per year. One of the most famous of Paris' underground breweries, Dumesnil, stayed in operation until the late 1960s.
In that decade, the network of corridors and galleries south of the Seine, long since abandoned by miners, became the unofficial playground for the young people of Paris. They explored the fantastical world beneath their feet, in some cases via entry points located in their very schools. Fascinated, these cataphiles ("catacomb lovers") read up on old books, explored the subterranean labyrinth, and drew up schematics that were passed around among fellow initiates as reverently as treasure maps.
As Robert Macfarlane writes in Underland, Paris-beneath-their-feet became "a place where people might slip into different identities, assume new ways of being and relating, become fluid and wild in ways that are constrained on the surface."
Some larger caves turned into notorious party zones: a 7-meter-tall gallery below the Val-de-Grâce hospital is widely known as "Salle Z." Over the last few decades, various other locations in subterranean Paris have hosted jazz and rock concerts and rave parties — like no other city, Paris really has an "underground music scene."
Hokusai's Great Wave as the backdrop to the "beach" under Paris.Credit: Reddit
Cataphiles vs. cataphobes
With popularity came increased reports of nuisance and crime — the tunnels provided easy access to telephone cables, which were stolen for the resale value of their copper.
The general public's "discovery" of the underground network led the city of Paris to officially interdict all access by non-authorized persons. That decree dates back to 1955, but the "underground police" have an understanding with seasoned cataphiles. Their main targets are so-called tourists, who by their lack of knowledge expose themselves to risk of injuries or worse, and degrade their surroundings, often leaving loads of litter in their wake.
The understanding does not extend to the IGC. Unlike in the 19th century, when weak cavities were shored up by purpose-built pillars, the policy now is to inject concrete to fill up endangered spaces — thus progressively blocking off parts of the network. That procedure has also been used to separate the Catacombs to prevent "infiltration" of the site by cataphiles.
Many subterranean streets have their own names, signs and all. This is the Rue des Bourguignons (Street of the Burgundians) below the Champs des Capucins (Capuchin Field), neither of which exists on the surface.Credit: Jean-François Gornet via Wikimedia and licensed under
The cataphiles, however, are fighting back. In a game of cat and mouse with the authorities, they are reopening blocked passages and creating chatières ("cat flaps") through which they can squeeze into chambers no longer accessible via other underground corridors.
Catacomb climate control
Alone against the unstoppable tide of concrete, the amateurs of Underground Paris would be helpless. But the fight against climate change may turn the subterranean labyrinths from a liability into an asset — and the City of Paris into an ally.
The UN's 2015 Climate Plan — concluded in Paris, by the way — requires the world to reduce greenhouse gas emissions by 75 percent by 2050. And Paris itself wants to be Europe's greenest city by 2030. More sustainable climate control of our living spaces would be a great help toward both targets. A lot of energy is spent heating houses in winter and cooling them in summer.
This is where the constant temperature of the Parisian tunnels comes in. It's not just good for brewing beer; it's a source of geothermal energy, says Fieldwork, an architectural firm based in Paris. It can be used to temper temperatures, helping to cool houses in summer and warming them in winter.
One catch for the cataphiles: it also works when the underground cavities are filled up with concrete. So perhaps one day, Paris Underground, fully filled up with concrete, will completely fall off the map, reducing the city's formerly real doppelgänger into an air conditioning unit.
Cool in summer, warm in winter: Paris Underground could become Paris A/C.Credit: Fieldwork
Strange Maps #1083
Got a strange map? Let me know at email@example.com.
Meconium contains a wealth of information.
- A new study finds that the contents of an infants' first stool, known as meconium, can predict if they'll develop allergies with a high degree of accuracy.
- A metabolically diverse meconium, which indicates the initial food source for the gut microbiota, is associated with fewer allergies.
- The research hints at possible early interventions to prevent or treat allergies just after birth.
The prevalence of allergies arising in childhood has increased over the last 50 years, with 30 percent of the human population now having some kind of atopic disease such as eczema, food allergies, or asthma. The cause of this increase is still subject to debate, though it has been associated with a number of factors, including changes to the gut microbiomes of infants.
A new study by Canadian researchers published in Cell Reports Medicine may shed further light on how these allergies develop in children by examining the contents of their first diaper.
The things you do for science
The research team examined the first stool of 100 infants from the CHILD Cohort Study. The first stool of an infant is a thick, green, horrid-looking substance called meconium. It consists of various things that the infant ingests during the second half of gestation. Additionally, it provides not only a snapshot of what the infant was exposed to during that time, but it also reveals what the food sources will be for the initial gut bacteria that colonize the baby's digestive tract.
The content of the meconium was examined and found to contain such varied elements as amino acids, lipids, carbohydrates, and myriad other substances.
A graph of the comparative, summed abundance of different elements in a metabolic pathway after scaling to median abundance of each metabolite. The blue figures are those children without atopy, the yellow ones show the data for those with an atopic condition. Petersen et al.
The authors fed this information into an algorithm that used this data, along with the identities of the bacteria present as well as the baby's overall health, to predict which infants would go on to develop allergies within one year. The algorithm got it right 76 percent of the time.
A way to prevent childhood allergies?
Infants whose meconium had a less diverse metabolic niche the initial microbes to settle in the gut were at the highest risk of developing allergies a year later. Many of these elements were associated with the presence or absence of different bacterial groups in the digestive system of the child, which play an increasingly appreciated role in our overall health and development. The findings were summarized by senior co-author Dr. Brett Finlay:
"Our analysis revealed that newborns who developed allergic sensitization by one year of age had significantly less 'rich' meconium at birth, compared to those who didn't develop allergic sensitization."
The findings could be used to help understand how allergies form and even how to prevent them. Co-author Dr. Stuart Turvey commented on this possibility:
"We know that children with allergies are at the highest risk of also developing asthma. Now we have an opportunity to identify at-risk infants who could benefit from early interventions before they even begin to show signs and symptoms of allergies or asthma later in life."
A model for early childhood allergies
Petersen et al.
As shown above, the authors constructed a model of how they believe metabolites and bacterial diversity help prevent allergies. Increased diversity of metabolic products in the meconium encourage the development of "healthy" families of bacteria, like Peptostreptococcaceae, which in turn promote the development of a healthy and diverse gut microbiome. Ultimately, such diversity decreases the likelihood that a child will develop allergies.