The anti-vaxx agenda of 'Plandemic'

A clip of this disingenuous documentary is making the rounds.

In this picture taken on April 29, 2020, an engineer shows an experimental vaccine for the COVID-19 coronavirus that was tested at the Quality Control Laboratory at the Sinovac Biotech facilities in Beijing.

Photo by Nicolas Asfouri / AFP
  • A new documentary, "Plandemic," states that it is uncovering a global cabal trying to implement forced vaccinations.
  • The first clip's interview subject, Judy Mikovits, is a known anti-vaxxer.
  • This agenda-based film features contradictory evidence and false claims while being championed as a beacon of truth.

In 1990, American attorney Mike Godwin coined "Godwin's law," which states that "as an online discussion grows longer, the probability of a comparison involving Nazis or Hitler approaches 1." When Nazis are invoked the debate is over. Godwin has made some exceptions, such as the Trump administration's implementation of refugee detention centers being compared to concentration camps. In general, little actually lives up to the horrors of the Holocaust, though anyone without credible evidence trying to win a debate foolishly invokes Hitler.

Cue COVID-19.

Over the past two days my social media feed has been dominated by a clip from the forthcoming documentary, "Plandemic." It only takes until the third paragraph of the film's description to discover that the current forced global vaccination program is rooted in Hitler's Germany. A few sentences later we "flash forward to 2020" to find out the "masters of the Pandemic" are finally finishing the job—on us.

Said clip features former researcher Judy Mikovits, who has become a minor celebrity on the anti-vaxx circuit. Her interview doubles as a promotion for her latest book, which is based on an ongoing war she's waging with Dr. Anthony Fauci. Her Twitter feed is filled with anti-Fauci rhetoric alongside glee that Donald Trump is now listening to her. She has explicitly called for the entire leadership of the COVID-19 response team to be fired.

Mikovits' story is not unlike Andrew Wakefield's, the discredited British physician who was paid to invent the vaccine-autism "conspiracy." In 2011, Mikovits attempted to link a newly discovered retrovirus to Chronic Fatigue Syndrome, only to partially retract the paper after the study could not be replicated. The journal, Science, later fully retracted Mikovits' paper, just as The Lancet had done with Wakefield's research (which also could not be replicated). In 2017, Mikovits published a book on retroviruses and...autism.

(Interestingly, in "Plandemic," Mikovits wants to end the Bayh-Dole Act, which allows federal funding recipients to file patents on inventions they've created. She cites a conflict of interest regarding Fauci. There is no mention of Wakefield's filing a patent for a measles vaccine while he was trying to discredit existing vaccines.)

As I wrote about last week, we've entered a strange territory where the far Left and far Right are converging. Truth is colliding with truthiness. "Plandemic" is based on a serious problem in our market-based system: pharmaceutical companies taking advantage of for-profit health care. We also, as Mikovits recommends, need to take care of our immune system. But to claim that we don't need a vaccine because our immune system will take care of us overlooks people born with pre-existing conditions, as well as the fact that this virus is unpredictable. Her "contrarian" attitude sells books and get clicks. What it doesn't do is help our situation. Contrary to the film's stated goal of waking people up, it accomplishes the opposite: by spreading misinformation, it's making people more fearful and ignorant of the scientific process.

The overall premise is true: Big Pharma is one of modernity's most lucrative industries. Billions are made on our suffering. For example, I've spent the last six months researching the chemical imbalance theory of mental health, which, beginning in the fifties through the present day, has been one of health care's greatest failures. There are real conspiracies that need to be addressed, such as this administration's complete failure to test Americans. But instead of putting our time and energy into, say, voting, we spin our wheels over invented conspiracies that are only furthering fear and confusion.

Below are seven instances that display how conspiracy theories are baked into "Plandemic." To borrow from Mike Godwin, perhaps Beres' law is number eight: "As an online discussion about vaccines grows longer, the probability of a comparison involving Bill Gates approaches 1." Because obviously, he's in there too.

1. Anti-vaccination agenda

The film opens with Mikovits' new book, Plague of Corruption, published by Skyhorse Publishing. This house has skin in the anti-vaxx game. The house's founder and publisher, Tony Lyons, said in 2014 that "my main focus in the publishing field has become books about autism and the connection between autism and vaccines." Skyhorse has published two of discredited physician Andrew Wakefield's anti-vaxx books. (Note: my last book was published by Carrel, a division of Skyhorse. I was not aware of the anti-vaxx connection until after it was published.) Mikovits' co-author, Kent Heckenlively, is a known anti-vaxxer and a founding editor of the anti-vaxx website, Age of Autism. The book's foreword was written by Robert F. Kennedy, a leader in the anti-vaxx movement. So when Mikovits states in "Plandemic" that she takes no issue with vaccinations, she sure hangs around plenty of people that do.

2. The flu vaccine linked to coronavirus

Mikovits links COVID-19 with the flu vaccine based on a January 2020 study of Department of Defense personnel. Indeed, getting the flu vaccine appeared to result in an increased risk of being infected with a coronavirus. The problem: the coronavirus studied was the common cold, not COVID-19. This study was also based on one flu season. A previous, larger study covering six flu seasons found no such association. In the film you're led to believe that getting a flu vaccine increases your risk of getting COVID-19. There's no evidence of that.

3. The ongoing debate over hydroxychloroquine

Mikovits expresses consternation that the anti-malarial drug, hydroxychloroquine, is not being used more. She states that it's been on the WHO Model Lists of Essential Medicines for 70 years. Almost: it was approved for medical use in America in 1955. While it has been successfully used to treat malaria, lupus, and rheumatoid arthritis, evidence of its efficacy in treating COVID-19 is conflicting. This does not mean that it might not work in combination with other drugs. The way the film is edited, however, makes it appear that Fauci is stating that evidence of hydroxychloroquine's efficacy is anecdotal in regards to any usage. His clip, specific to COVID-19, is right after Mikovits' citation of the WHO list. In this case, Fauci is right: evidence of hydroxychloroquine's efficacy in treating COVID-19 is, to date, anecdotal. The film then flashes to a doctor berating Fauci's assessment. He then angrily asks Fauci if he's going to clinically test a vaccine. Considering over 70 are in various phases of clinical trials around the world, the answer is likely yes, but the film makes it seem the opposite.

4. The Bakersfield doctors

Here they are again. Dr. Dan Erickson and Dr. Artin Massihi, the team that runs an urgent care center in Bakersfield, were forceful in their assessment that sheltering in place is nonsense. Their videos were taken off of social media for spreading misinformation, yet that makes perfect fodder for "Plandemic." To be fair, in one clip they make a good point: humans needs to be exposed to bacteria. Our immune systems require exposure. In normal times, we've gone overboard with antibacterial soap. Kids need dirt.

The problem is that this point is conflated with sheltering at home. What we're avoiding is not bacteria, but overwhelming our health care system. Sure, a large percentage of those infected with COVID-19 are asymptomatic. Doctors are still trying to understand why that is. We're protecting vulnerable populations whose immune systems cannot handle it as well as doctors and nurses. The film's editing is disingenuous. It makes it appear that if we only got a little COVID, we'd all be alright. The debate over herd immunity is a separate conversation. The short-term solution is sheltering at home. It's not about taking away our freedom. It's buying researchers and hospitals time. These doctors should know better.

Judy Mikovits in "The Plandemic."

5. Shady Montage

The film claims that we're being driven to hate one another by our media outlets. That is a debatable but important point. Social media is certainly polarizing. We know that. This claim is made over a montage featuring Alex Jones (who recently contemplated cannibalism) and Sean Hannity (a leading voice for the sheltering at home protest movement) alongside comedians Trevor Noah and John Oliver. Sure, the latter are politically liberal. But since when is cannibalism a conservative principle? This montage makes you feel as if all media is flawed. The implication is that you can only turn to films like "Plandemic" for the truth. In criticizing the "us versus them" mentality, the filmmakers are trying to win viewers over to "their" side.

6. Cult Dog Whistling

The company behind this film made its mark by distributing and marketing the documentary that led to the book, "The Secret." Barbara Ehrenreich said it best when stating that the self-help techniques inside this book—"ask, believe, receive"—promotes a failure to engage with reality while promoting political complacency. The author, Rhonda Byrne, tows a very old myth: You're the only reason that you're in the shape you're in. If you're having problems, that's on you. You're not asking hard enough. "Plandemic" relies on a tried and tested cult technique: the world is toxic, but we have the answers. This is indicated when Mikovits says, "Hopefully this is the wake-up call for all America to realize this makes no sense and we win because it will take down this whole program." You're either with us or against us. The same mostly white and affluent demographic targeted by Byrne makes up a large portion of the anti-vaccination movement. Magical thinking is easy when you're not poor or oppressed.

7. Surprise outbreak

The clip ends with Fauci speaking at a 2017 commencement address. He states there is no doubt there will be a surprise outbreak due to a pandemic. This theatrical ending implies that he's been in on this the whole time (wink, wink). But let's consider a 2007 review by a team of scientists in Hong Kong:

"Coronaviruses are well known to undergo genetic recombination, which may lead to new genotypes and outbreaks. The presence of a large reservoir of SARS-CoV-like viruses in horseshoe bats, together with the culture of eating exotic mammals in southern China, is a time bomb. The possibility of the re-emergence of SARS and other novel viruses from animals or laboratories and therefore the need for preparedness should not be ignored."

Obama warned of a potential pandemic too. In fact, a lot of researchers have been sounding the alarm. This Larry Brilliant interview from 2017 is rather timely today. That does not fit the anti-Fauci rhetoric Mikovits is banking her career on, however. Every agenda has a target. While "Plandemic" says the goal is our freedom, the reality is anything but.

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Stay in touch with Derek on Twitter and Facebook. His next book is "Hero's Dose: The Case For Psychedelics in Ritual and Therapy."

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New research establishes an unexpected connection.

Reactive oxygen species (ROS) accumulate in the gut of sleep-deprived fruit flies, one (left), seven (center) and ten (right) days without sleep.

Image source: Vaccaro et al, 2020/Harvard Medical School
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  • Surprisingly, the direct cause seems to be a buildup of Reactive Oxygen Species in the gut produced by sleeplessness.
  • When the buildup is neutralized, a normal lifespan is restored.

We don't have to tell you what it feels like when you don't get enough sleep. A night or two of that can be miserable; long-term sleeplessness is out-and-out debilitating. Though we know from personal experience that we need sleep — our cognitive, metabolic, cardiovascular, and immune functioning depend on it — a lack of it does more than just make you feel like you want to die. It can actually kill you, according to study of rats published in 1989. But why?

A new study answers that question, and in an unexpected way. It appears that the sleeplessness/death connection has nothing to do with the brain or nervous system as many have assumed — it happens in your gut. Equally amazing, the study's authors were able to reverse the ill effects with antioxidants.

The study, from researchers at Harvard Medical School (HMS), is published in the journal Cell.

An unexpected culprit

The new research examines the mechanisms at play in sleep-deprived fruit flies and in mice — long-term sleep-deprivation experiments with humans are considered ethically iffy.

What the scientists found is that death from sleep deprivation is always preceded by a buildup of Reactive Oxygen Species (ROS) in the gut. These are not, as their name implies, living organisms. ROS are reactive molecules that are part of the immune system's response to invading microbes, and recent research suggests they're paradoxically key players in normal cell signal transduction and cell cycling as well. However, having an excess of ROS leads to oxidative stress, which is linked to "macromolecular damage and is implicated in various disease states such as atherosclerosis, diabetes, cancer, neurodegeneration, and aging." To prevent this, cellular defenses typically maintain a balance between ROS production and removal.

"We took an unbiased approach and searched throughout the body for indicators of damage from sleep deprivation," says senior study author Dragana Rogulja, admitting, "We were surprised to find it was the gut that plays a key role in causing death." The accumulation occurred in both sleep-deprived fruit flies and mice.

"Even more surprising," Rogulja recalls, "we found that premature death could be prevented. Each morning, we would all gather around to look at the flies, with disbelief to be honest. What we saw is that every time we could neutralize ROS in the gut, we could rescue the flies." Fruit flies given any of 11 antioxidant compounds — including melatonin, lipoic acid and NAD — that neutralize ROS buildups remained active and lived a normal length of time in spite of sleep deprivation. (The researchers note that these antioxidants did not extend the lifespans of non-sleep deprived control subjects.)

fly with thought bubble that says "What? I'm awake!"

Image source: Tomasz Klejdysz/Shutterstock/Big Think

The experiments

The study's tests were managed by co-first authors Alexandra Vaccaro and Yosef Kaplan Dor, both research fellows at HMS.

You may wonder how you compel a fruit fly to sleep, or for that matter, how you keep one awake. The researchers ascertained that fruit flies doze off in response to being shaken, and thus were the control subjects induced to snooze in their individual, warmed tubes. Each subject occupied its own 29 °C (84F) tube.

For their sleepless cohort, fruit flies were genetically manipulated to express a heat-sensitive protein in specific neurons. These neurons are known to suppress sleep, and did so — the fruit flies' activity levels, or lack thereof, were tracked using infrared beams.

Starting at Day 10 of sleep deprivation, fruit flies began dying, with all of them dead by Day 20. Control flies lived up to 40 days.

The scientists sought out markers that would indicate cell damage in their sleepless subjects. They saw no difference in brain tissue and elsewhere between the well-rested and sleep-deprived fruit flies, with the exception of one fruit fly.

However, in the guts of sleep-deprived fruit flies was a massive accumulation of ROS, which peaked around Day 10. Says Vaccaro, "We found that sleep-deprived flies were dying at the same pace, every time, and when we looked at markers of cell damage and death, the one tissue that really stood out was the gut." She adds, "I remember when we did the first experiment, you could immediately tell under the microscope that there was a striking difference. That almost never happens in lab research."

The experiments were repeated with mice who were gently kept awake for five days. Again, ROS built up over time in their small and large intestines but nowhere else.

As noted above, the administering of antioxidants alleviated the effect of the ROS buildup. In addition, flies that were modified to overproduce gut antioxidant enzymes were found to be immune to the damaging effects of sleep deprivation.

The research leaves some important questions unanswered. Says Kaplan Dor, "We still don't know why sleep loss causes ROS accumulation in the gut, and why this is lethal." He hypothesizes, "Sleep deprivation could directly affect the gut, but the trigger may also originate in the brain. Similarly, death could be due to damage in the gut or because high levels of ROS have systemic effects, or some combination of these."

The HMS researchers are now investigating the chemical pathways by which sleep-deprivation triggers the ROS buildup, and the means by which the ROS wreak cell havoc.

"We need to understand the biology of how sleep deprivation damages the body so that we can find ways to prevent this harm," says Rogulja.

Referring to the value of this study to humans, she notes,"So many of us are chronically sleep deprived. Even if we know staying up late every night is bad, we still do it. We believe we've identified a central issue that, when eliminated, allows for survival without sleep, at least in fruit flies."

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