The Helpless Y Chromosome

Question: Is the Y chromosome prone to mutations?

Marianne Legato: The Y chromosome is definitely unique among all the chromosomes. Over most of its extent, it can’t exchange with its partner the X chromosome to repair its deficiencies or mutations in DNA. It’s learned to repair itself in an interesting and unique way. The issues with the Y chromosome are that they are exposed to environmental toxins because they are housed outside the body in the scrotal sack. Many millions are produced every day and, therefore, mutations are far more frequent in the Y chromosome than in the X or indeed in any of the other chromosomes. So the male drives evolutionary development because of this extraordinary proliferation of mutations that are characteristic of sperm and the Y chromosome.

The masculine chromosome is unique in its inability to repair itself, making it exceptionally prone to mutation and pollution.

Harness the Power of Calm

Tap into the "Rest and Digest" System to Achieve Your Goals

Big Think Edge
  • In the fast-paced workplaces and productivity-focused societies many of us inhabit today, it is easy to burnout.
  • Emma Seppälä, a Stanford researcher on human happiness, recommends tapping into the parasympathetic nervous system instead—"rest and digest"rather than "fight or flight."
  • Aiming for energy management rather than time management will give you the resilience you need to excel at the things that really matter in your life and career, rather than living "mostly off" by attempting to seem "always on."

Apple co-founder says we should all ditch Facebook — permanently

Steve Wozniak doesn't know if his phone is listening, but he's minimizing risks.

Photo by Bryan Steffy/Getty Images
Technology & Innovation
  • Steve Wozniak didn't hold back his feelings about the social media giant when stopped at an airport.
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  • Wozniak deleted his Facebook account last year, recommending that "most people" should do the same.
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Where the evidence of fake news is really hiding

When it comes to sniffing out whether a source is credible or not, even journalists can sometimes take the wrong approach.

Sponsored by Charles Koch Foundation
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  • When judging whether a piece of media is true or not, most of us focus too much on the source itself. Knowledge has a context, and it's important to look at that context when trying to validate a source.
  • The opinions expressed in this video do not necessarily reflect the views of the Charles Koch Foundation, which encourages the expression of diverse viewpoints within a culture of civil discourse and mutual respect.
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