From Sci-Fi to Sci-Fact: The New Frontier of Neuroscience
Question: What is the most exciting part of brain science for you?
Alfredo Quinones-Hinojosa: I think the most exciting part of what I do right now is exactly the fact that what we are doing is giving patients new hope; that we're looking at a disease, which is brain cancer, that people have looked at for hundreds of years and we have not been able to understand, and we're finally perhaps beginning to scratch the surface, we're beginning to look at an old disease with new eyes.
And what new eyes are those is the fact that within brain cancer there may be a small population of cells that have the ability to recreate the same type of cancer, which means that despite the fact that we can actually do a perfect surgical resection and we can take a lot of these tumors out, these patients eventually continue to progress, perhaps because we're leaving those small little cells back there that are able to recreate the whole tumor. So our role now is to understand those small cells. We're not looking at the whole tissue that we're leaving behind, but we're looking at a special subset of population of cells that we can potentially affect; that we can potentially damage their ability to recreate that cancer. And I think, to me, that's absolute dynamite, because it may actually change the paradigm and the way that we treat brain cancer currently.
Question: How will brain cancer be treated differently in the future?
Alfredo Quinones-Hinojosa: In the future the way that I vision-- my vision is that every patient will be treated slightly different, depending on their ability, depending on their markers, depending on the kind of cells they have in their brain. Right now the way that we are categorizing brain cancer is in different categories, and we lump all patients together in different categories, when in reality we are beginning to understand that every patient is different. Just like we're all human but we have different characteristics, different personality, tumors are probably the same way, and no one single treatment can be tailored for many patients.
You're probably going to individualize treatment, and that excites me. The other thing that excites me about what we do in the operating room, and in the laboratory, is the fact that we'll probably open doors for other fields to conceive the way to unleash the potential of the brain. If brain cancer is a disease that continuously has the ability to grow-- there are many other diseases in the human brain where we need that growth, like in multiple sclerosis, Huntington's disease, Parkinson's disease. So our role is to try to learn from that of normal growth so we can apply that knowledge to people who need growth in parts of the brain that are thirsty for new cells.
Recorded on: July 2, 2008
Image courtesy of Shutterstock.com
Tumors are as unique as people, says Dr. Q. In the future, every patient is going to a receive treatment for brain cancer that is as individual as the person themselves.
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A growing body of research shows promising signs that the keto diet might be able to improve mental health.
- The keto diet is known to be an effective tool for weight loss, however its effects on mental health remain largely unclear.
- Recent studies suggests that the keto diet might be an effective tool for treating depression, and clearing up so-called "brain fog," though scientists caution more research is necessary before it can be recommended as a treatment.
- Any experiments with the keto diet are best done in conjunction with a doctor, considering some people face problems when transitioning to the low-carb diet.
She met mere mortals with and without the Vatican's approval.
- For centuries, the Virgin Mary has appeared to the faithful, requesting devotion and promising comfort.
- These maps show the geography of Marian apparitions – the handful approved by the Vatican, and many others.
- Historically, Europe is where most apparitions have been reported, but the U.S. is pretty fertile ground too.
Thinking your life is worthwhile is correlated with a variety of positive outcomes.
- A new study finds that adults who feel their lives are meaningful have better health and life outcomes.
- Adults who felt their lives were worthwhile tended to be more social and had healthier habits.
- The findings could be used to help improve the health of older adults.
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