Exploring the Future Frontiers of Human Health, with Francois Nader
The President & CEO of NPS Pharmaceuticals predicts tremendous growth for the pharmaceutical industry in the coming years as new cures and treatments are developed.
Francois Nader, MD, has been President, Chief Executive Officer and a member of the Board of Directors of NPS Pharma since 2008. During his tenure, Dr. Nader transformed NPS Pharma into a leading global biotechnology company focused on pioneering and delivering innovative therapies that transform the lives of patients with rare diseases worldwide.
Dr. Nader is a 30-year veteran of the healthcare industry. He joined NPS Pharma in 2006 as chief medical and commercial officer and was promoted to chief operating officer in 2007. Previously, he was a venture partner at Care Capital. Dr. Nader served on the North America Leadership Team of Aventis and its predecessor companies and held a number of executive positions including senior vice-president, integrated healthcare markets and North America medical and regulatory affairs. Prior, Dr. Nader led the global commercial operations at the Pasteur Vaccines division of Rhone-Poulenc.
Dr. Nader earned his French Doctorate in Medicine from St. Joseph University (Lebanon) and his Physician Executive MBA from the University of Tennessee. Dr. Nader is the immediate past chair of the Board of Trustees for BioNJ, New Jersey’s trade organization representing the biotechnology industry. He is also a Board member of the Biotechnology Industry Organization (BIO), the New Jersey Chamber of Commerce, Trevena, Inc., Clementia Pharmaceuticals, Inc. and Acceleron Pharma Inc. In 2013, Dr. Nader was recognized as the Ernst and Young National Life Science Entrepreneur of the Year.
Francois Nader: I think we have tremendous, tremendous growth, tremendous potential in exploring the frontier of human beings. We are just at the very, very beginning of a very exciting adventure. And think of diseases as common cold, right. There is nothing terribly unusual about common cold, right. Yet we don’t have a cure for common cold yet, okay. Which is kind of ironic, right. Which means that innovation could be very small for small things like common cold or big things like Alzheimer’s and diabetes. We have multiple products for the diabetes today. We don’t have a cure for diabetes yet. Actually if you add Alzheimer’s and diabetes it could bankrupt our healthcare system. Yet we don’t have a cure for diabetes and we don’t know how to deal with Alzheimer’s yet. So if I look at the future a couple of things will happen.
One, we have phenomenal tools that will enable us to diagnose and to be more specific in better understanding the mechanism of virtually any disease. And the second aspect would be based on that we can start now, charter the road to better understanding the brain which will be a huge advancement.
We don’t know much about the brain. We know a few things here and there. But the brain is a huge unknown scientifically still. We don’t have a lot of tools yet to better understand how we think, the memory and everything related to our behavior. So the brain will be probably the next frontier.
But we should not forget that we have still about 6,000 rare diseases that do not have a treatment so we have a lot of work to do. And we cannot do it alone. I mean money and investment is one thing but we need to continue working on the framework of the regulatory agencies and how we can partner with the regulators to have a clearer path forward to having the new drugs approved.
The biggest challenge we face is science is moving so fast that the regulators have to catch up. They have to catch up to understand and catch up even more to regulate us which is a very daunting challenge and I really believe that the regulators are doing the right things in most of the cases. But at the same time I can only see the challenges that they have to better understand how the science is progressing. And you hear every day about the genomes and our understanding of the genomes. I mean this is absolutely flabbergasting the progress we’ve made over the last 15 years in better understanding the inner mechanics of how we work. And from there will come new medications, will come new cures, new treatments.
The President & CEO of NPS Pharmaceuticals predicts tremendous growth for the pharmaceutical industry in the coming years as new cures and treatments are developed. He also speaks about the broad scope of pharmaceutical research. The coming decades will see advances in treating minor issues such as the common cold, as well as broad steps forward in the fight against the frightening destruction of Alzheimer's disease.
The biggest challenge moving forward, says Nader, is for regulators to keep up with the radical growth and achievements sure to come. Policy and science need to remain on the same page in order to maximize the positive effects of research.
Here's the science of black holes, from supermassive monsters to ones the size of ping-pong balls.
- There's more than one way to make a black hole, says NASA's Michelle Thaller. They're not always formed from dead stars. For example, there are teeny tiny black holes all around us, the result of high-energy cosmic rays slamming into our atmosphere with enough force to cram matter together so densely that no light can escape.
- CERN is trying to create artificial black holes right now, but don't worry, it's not dangerous. Scientists there are attempting to smash two particles together with such intensity that it creates a black hole that would live for just a millionth of a second.
- Thaller uses a brilliant analogy involving a rubber sheet, a marble, and an elephant to explain why different black holes have varying densities. Watch and learn!
- Bonus fact: If the Earth became a black hole, it would be crushed to the size of a ping-pong ball.
From time-traveling billiard balls to information-destroying black holes, the world's got plenty of puzzles that are hard to wrap your head around.
- While it's one of the best on Earth, the human brain has a lot of trouble accounting for certain problems.
- We've evolved to think of reality in a very specific way, but there are plenty of paradoxes out there to suggest that reality doesn't work quite the way we think it does.
- Considering these paradoxes is a great way to come to grips with how incomplete our understanding of the universe really is.
In a breakthrough for nuclear fusion research, scientists at China's Experimental Advanced Superconducting Tokamak (EAST) reactor have produced temperatures necessary for nuclear fusion on Earth.
- The EAST reactor was able to heat hydrogen to temperatures exceeding 100 million degrees Celsius.
- Nuclear fusion could someday provide the planet with a virtually limitless supply of clean energy.
- Still, scientists have many other obstacles to pass before fusion technology becomes a viable energy source.
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