from the world's big
New vaccine (for cats) nixes allergic reactions for humans
You want one. Now you may be able to survive one.
Photo credit: Jie Zhao / Getty contributor
- Cats live in a quarter of Western households.
- Allergies to them are common and can be dangerous.
- A new approach targets the primary trouble-causing allergen.
Many cat lovers struggle with cat allergies that range from sniffles and runny noses to more severe reaction reactions that can send a felinophile racing to the ER.
For some, anti-allergy medications suffice, though they're not without side effects — others just suffer the symptoms in exchange for the privilege of having a cat in their families. (Certainly their cats consider it a privilege.) Some people simply stay away from cats.
This is may all soon change, though. This month, researchers in Zürich published preclinical data in The Journal of Allergy and Clinical Immunology that offers a different type of solution: a vaccination. Not for you. For the cat.
Neutralizing Fel d 1
A cat playing in a yard in Beijing, China. Photo credit: Jie Zhao / Corbis via Getty Images
According to the paper, cats live in about 25 percent of households in Western countries, and allergies to them afflict about 10 percent of nearby humans. The most common cat allergen is called "Fel d 1," largely produced by a cat's sebaceous glands and found in feline saliva, anal glands, sebaceous glands, skin, and fur.
Fel-CuMVTT, to be marketed as HypoCat™ vaccine by Swiss company HypoPet, was developed through a collaboration between researchers at the Latvian Biomedical Research and Study Centre, in Riga, and the veterinary school at the University of Zürich — along with scientists at the Functional Genomics Center Zürich.
How the vaccine works
Image source: The Journal of Allergy and Clinical Immunology
The vaccine brings together recombinant Fel d 1 with a virus-like particle (or "VLP") derived from the cucumber mosaic virus. "We are very pleased to publish this data which shows our HypoCat™ vaccine is able to produce high levels of antibodies in cats and that these antibodies can bind and neutralize the Fel d 1 allergen produced by the animals," says Dr. Gary Jennings, HypoPet CEO.
Cats treated with the vaccine were found to be less likely to trigger allergic reactions in humans exposed to them. The vaccine is also reported to have been "well tolerated without any overt toxicity" for the feline test subjects. The published data is culled from four separate studies that involved 54 cats.
A double benefit
Image source: Mettus / Shutterstock
The benefits of an effective cat-allergy treatment are two-fold. First off, these allergies are not only annoying — and sometimes much more than that — but a cat allergy in kids living with felines is understood to be a strong factor in the development of childhood asthma. A simple three-dose course of vaccine — as administered in the testing — could alleviate cat-owners' suffering and the risk to young ones.
Households with allergy sufferers, especially children, often find themselves forced to evict a beloved family member, a traumatic experience for all concerned, and a leading cause of cat abandonment. According to HypoCat, U.S. shelters take in 3.4 million cats annually — 1.4 million of these are eventually euthanized.
Educators and administrators must build new supports for faculty and student success in a world where the classroom might become virtual in the blink of an eye.
- If you or someone you know is attending school remotely, you are more than likely learning through emergency remote instruction, which is not the same as online learning, write Rich DeMillo and Steve Harmon.
- Education institutions must properly define and understand the difference between a course that is designed from inception to be taught in an online format and a course that has been rapidly converted to be offered to remote students.
- In a future involving more online instruction than any of us ever imagined, it will be crucial to meticulously design factors like learner navigation, interactive recordings, feedback loops, exams and office hours in order to maximize learning potential within the virtual environment.
A leading British space scientist thinks there is life under the ice sheets of Europa.
- A British scientist named Professor Monica Grady recently came out in support of extraterrestrial life on Europa.
- Europa, the sixth largest moon in the solar system, may have favorable conditions for life under its miles of ice.
- The moon is one of Jupiter's 79.
Neil deGrasse Tyson wants to go ice fishing on Europa<div class="rm-shortcode" data-media_id="GLGsRX7e" data-player_id="FvQKszTI" data-rm-shortcode-id="f4790eb8f0515e036b24c4195299df28"> <div id="botr_GLGsRX7e_FvQKszTI_div" class="jwplayer-media" data-jwplayer-video-src="https://content.jwplatform.com/players/GLGsRX7e-FvQKszTI.js"> <img src="https://cdn.jwplayer.com/thumbs/GLGsRX7e-1920.jpg" class="jwplayer-media-preview" /> </div> <script src="https://content.jwplatform.com/players/GLGsRX7e-FvQKszTI.js"></script> </div>
Water Vapor Above Europa’s Surface Deteced for First Time<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="9c4abc8473e1b89170cc8941beeb1f2d"><iframe type="lazy-iframe" data-runner-src="https://www.youtube.com/embed/WQ-E1lnSOzc?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span>
New study shows white dwarf stars create an essential component of life.
- White dwarf stars create carbon atoms in the Milky Way galaxy, shows new study.
- Carbon is an essential component of life.
- White dwarfs make carbon in their hot insides before the stars die.
What Are White Dwarf Stars?<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="7b046e546ce994682b2553a8c978eb32"><iframe type="lazy-iframe" data-runner-src="https://www.youtube.com/embed/77a1KSxfaR0?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span>
The renowned magician recently joined Big Think CEO and cofounder Victoria Brown for a wide-ranging discussion.
- Penn Jillette is an American magician best known for his work as part of the magic duo Penn and Teller.
- Jillette has also written eight books, co-hosted the Showtime show "Bullshit," and produced the film "Tim's Vermeer."
- In the interview, Jillette talks about how libertarianism has been distorted in the U.S., and why the democratization of media hasn't produced a utopia.