Study finds the real reason you get goosebumps

A hair-raising study 

In animals, many organs are made of three kinds of tissue: epithelium, mesenchyme, and nerve. In the skin, which is an organ, a nerve connects to muscle in the mesenchyme. This nerve is part of the sympathetic nervous system and helps maintain homeostasis. The muscle itself is connected to stem cells in the epithelium that heal wounds and regenerate hair follicles.

The researchers focused on mice, as is typical in these studies, but suggest that the findings are also applicable to humans given the similarity between our skin and hair cells.

The researchers examined the behavior and structure of the nerve under an electron microscope. To their surprise, the nerve was not only attached to the previously mentioned muscle tissue but also wrapped around hair follicle stem cells.

In normal conditions, the sympathetic nervous system is always operating at a low level. This keeps the body functioning normally. When the researchers observed this behavior, they noticed signals being sent by the nervous system to the stem cells in the hair follicles. These signals seem to keep the stem cells at the ready for potential use.

However, when the researchers exposed the tissues to the cold, the activity ramped up. A flood of neurotransmitters was released, and the stem cells activated. This prompted new hair growth to begin.

Another experiment dove into how the nerve reached the stem cells in the first place. Co-Author Yulia Shwartz explained the findings in a press release:

"We discovered that the signal comes from the developing hair follicle itself. It secretes a protein that regulates the formation of the smooth muscle, which then attracts the sympathetic nerve. Then in the adult, the interaction turns around, with the nerve and muscle together regulating the hair follicle stem cells to regenerate the new hair follicle. It's closing the whole circle -- the developing hair follicle is establishing its own niche."

Putting this together, it appears that goosebumps are part of a two-phased response to cold. In the first, the muscle below the skin is stimulated to form goosebumps. If this stimulation lasts long enough, the second phase kicks in, with the sympathetic nervous system calling for new hair growth and repairs for the old ones to be made in response to the cold.

This is interesting and all, but what possible application could this information have?

In their press release, the authors suggest that further research can focus on how the body repairs itself in response to environmental stimuli in various situations. The findings also imply that other currently unsuspected connections between the sympathetic nervous system and other parts of the body exist. These potential interactions will undoubtedly be searched for and examined.

Everybody gets goosebumps now and then. We've always assumed we knew why we still get them, even though the hypothesis had some holes. This study's findings show that the benefits of getting goosebumps are more complex than initially thought. It just goes to remind us that we still have much to learn about even the most mundane things.