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DIY electrical brain stimulation is a worrying new trend
There's still a lot even doctors don't know about it.
- Scientists are experimenting with applying electrical current to brains as a potential therapy and enhancement.
- A wave of DIY brain-shocking is worrying experts.
- Would you ever zap your own brain to see what happens? DIY and direct-to-consumer devices are available, but researchers have called for an open dialog with the DIY community about the risks.
Transcranial electrical stimulation, or "tES," involves applying mild, controlled electrical shocks non-invasively to a subject's brain. Scientists have been interested in learning if and how tES can address psychiatric problems and maybe enhance creativity and cognitive abilities.
Now, otherwise-normal people are performing tES experiments on themselves using transcranial direct current stimulation, or "tDCS," in which a mild, direct current is delivered to the brain via electrodes placed on the scalp. Doctors are concerned. A paper published in Creativity Research Journal by a team of Georgetown psychologists warns that this is dangerous territory to be playing in. The potential dangers are unclear, as are the possible benefits, and the procedure and hardware are unregulated. There are already direct-to-consumer products available, and there are build-your-own instructions online.
Why are scientists interested in tES?
Electrodes are applied to a test subject's head prior to performing cognitive tasks. Researchers are interested in studying how tES affects cognition, fatigue, mood, and other aspects of the mind.
The underlying idea
According to a 2017 article in Frontiers in Human Neuroscience, scientists are exploring these methods as a way to "establish an association between the application of weak electric currents to specified locations on the scalp and changes in a behavioral index of interest. An implicit assumption of this approach is that the electric currents modulate neural activity in the regions beneath the scalp locations and accordingly affect behaviors supported by these neural regions."
Why scientists care
It's not just curiosity. The above article also notes that such procedures "can modulate a wide-range of behavioral processes, and ameliorate deficits in several neuropsychiatric disorders." In particular, electrical stimulation has been shown to be useful in treating depression.
It's important to note that tES is not electro-convulsive (ECT), or "shock," therapy. Rather, tES involves much smaller charges of electricity than the more radical ECT.
Some tantalizing research, including earlier work at Georgetown, suggest that it's possible to boost one's creativity with the application of electrical current to the brain. Study co-author Adam Green—who also contributed to the new paper by warning of the dangers associated with home-brewed tES—made tES's potential clear in 2016: "The findings of this study offer the new suggestion that giving individuals a 'zap' of electrical stimulation can enhance the brain's natural thinking cap [and] creativity." Noting that this constitutes "a departure from traditional research that treats creativity as a static trait," Green explained, "we focused on creativity as a dynamic state that can change quickly within an individual when they 'put their thinking cap on.'"
That's not all. That study's other author, Peter Turkeltaub, pointed out electrical treatments' promise for resolving functional brain issues. As an example, he offered "People with speech and language difficulties often can't find or produce the words they need. Enhancing creative analogical reasoning might allow them to find alternate ways of expressing their ideas using different words, gestures, or other approaches to convey a similar meaning."
The concern about DIY tES
A homemade tDCS controller.
The new paper, "Neuroethical and Social Implications of Using Transcranial Electrical Stimulation to Augment Creative Cognition," by Adam B. Weinberger, Robert A. Cortes, James Giordano, and Green, says that home-use and direct-to-consumer products raise issues that are important to address when considering "the viability, safety, value, and provision of tES" particularly in regard to "clinical, occupational, and lifestyle applications."
Giordano told EurekAlert! that "DIY applications can pose certain challenges in that constraints may not be appreciated or adhered to, and in some cases, not regarded."
That this trend has emerged isn't that surprising, according to Green, who said, "There are multiple potential concerns with DIY-ers self-administering electric current to their brains, but this use of tES may be inevitable."
Part of the danger, though, lies in so much still being unknown about the way the brain works and the manner in which it interacts with electricity on a fine-grained level. One type of damage is especially worrisome to Green, who noted that "anytime there is risk of harm with a technology, the scariest risks are those associated with kids and the developing brain."
The trend is not totally out of control, and there may be an upside
The Brain Driver, a direct-to-consumer tDCS device.
Giordano recognizes that "the DIY community is certainly not cavalier or a proverbial 'wild west' environment. Many DIY individuals and groups employ independent institutional review boards, or establish self-regulating oversight committees to guide the scope and tenor of their work." And he admits a possible benefit to all this freelancing, saying "the nature of DIY engagement can also provide an environment of avant-garde iterations of science, technology, methods and applications. This is not necessarily a bad thing, per se, as it may, in fact 'push the envelope' to some extent."
"But there is what I feel to be justified concern that such attempts could incur safety issues," continued the neuroethicist. "In that light, we have called for an ongoing dialog with the DIY community to enable improved communication of techniques and effects so as to remain aware of what's being done, how, and the outcomes of such work that may be important to advancing the field and clinical care of any adverse manifestations."
How would the ability to genetically customize children change society? Sci-fi author Eugene Clark explores the future on our horizon in Volume I of the "Genetic Pressure" series.
- A new sci-fi book series called "Genetic Pressure" explores the scientific and moral implications of a world with a burgeoning designer baby industry.
- It's currently illegal to implant genetically edited human embryos in most nations, but designer babies may someday become widespread.
- While gene-editing technology could help humans eliminate genetic diseases, some in the scientific community fear it may also usher in a new era of eugenics.
Tribalism and discrimination<p>One question the "Genetic Pressure" series explores: What would tribalism and discrimination look like in a world with designer babies? As designer babies grow up, they could be noticeably different from other people, potentially being smarter, more attractive and healthier. This could breed resentment between the groups—as it does in the series.</p><p>"[Designer babies] slowly find that 'everyone else,' and even their own parents, becomes less and less tolerable," author Eugene Clark told Big Think. "Meanwhile, everyone else slowly feels threatened by the designer babies."</p><p>For example, one character in the series who was born a designer baby faces discrimination and harassment from "normal people"—they call her "soulless" and say she was "made in a factory," a "consumer product." </p><p>Would such divisions emerge in the real world? The answer may depend on who's able to afford designer baby services. If it's only the ultra-wealthy, then it's easy to imagine how being a designer baby could be seen by society as a kind of hyper-privilege, which designer babies would have to reckon with. </p><p>Even if people from all socioeconomic backgrounds can someday afford designer babies, people born designer babies may struggle with tough existential questions: Can they ever take full credit for things they achieve, or were they born with an unfair advantage? To what extent should they spend their lives helping the less fortunate? </p>
Sexuality dilemmas<p>Sexuality presents another set of thorny questions. If a designer baby industry someday allows people to optimize humans for attractiveness, designer babies could grow up to find themselves surrounded by ultra-attractive people. That may not sound like a big problem.</p><p>But consider that, if designer babies someday become the standard way to have children, there'd necessarily be a years-long gap in which only some people are having designer babies. Meanwhile, the rest of society would be having children the old-fashioned way. So, in terms of attractiveness, society could see increasingly apparent disparities in physical appearances between the two groups. "Normal people" could begin to seem increasingly ugly.</p><p>But ultra-attractive people who were born designer babies could face problems, too. One could be the loss of body image. </p><p>When designer babies grow up in the "Genetic Pressure" series, men look like all the other men, and women look like all the other women. This homogeneity of physical appearance occurs because parents of designer babies start following trends, all choosing similar traits for their children: tall, athletic build, olive skin, etc. </p><p>Sure, facial traits remain relatively unique, but everyone's more or less equally attractive. And this causes strange changes to sexual preferences.</p><p>"In a society of sexual equals, they start looking for other differentiators," he said, noting that violet-colored eyes become a rare trait that genetically engineered humans find especially attractive in the series.</p><p>But what about sexual relationships between genetically engineered humans and "normal" people? In the "Genetic Pressure" series, many "normal" people want to have kids with (or at least have sex with) genetically engineered humans. But a minority of engineered humans oppose breeding with "normal" people, and this leads to an ideology that considers engineered humans to be racially supreme. </p>
Regulating designer babies<p>On a policy level, there are many open questions about how governments might legislate a world with designer babies. But it's not totally new territory, considering the West's dark history of eugenics experiments.</p><p>In the 20th century, the U.S. conducted multiple eugenics programs, including immigration restrictions based on genetic inferiority and forced sterilizations. In 1927, for example, the Supreme Court ruled that forcibly sterilizing the mentally handicapped didn't violate the Constitution. Supreme Court Justice Oliver Wendall Holmes wrote, "… three generations of imbeciles are enough." </p><p>After the Holocaust, eugenics programs became increasingly taboo and regulated in the U.S. (though some states continued forced sterilizations <a href="https://www.uvm.edu/~lkaelber/eugenics/" target="_blank">into the 1970s</a>). In recent years, some policymakers and scientists have expressed concerns about how gene-editing technologies could reanimate the eugenics nightmares of the 20th century. </p><p>Currently, the U.S. doesn't explicitly ban human germline genetic editing on the federal level, but a combination of laws effectively render it <a href="https://academic.oup.com/jlb/advance-article/doi/10.1093/jlb/lsaa006/5841599#204481018" target="_blank" rel="noopener noreferrer">illegal to implant a genetically modified embryo</a>. Part of the reason is that scientists still aren't sure of the unintended consequences of new gene-editing technologies. </p><p>But there are also concerns that these technologies could usher in a new era of eugenics. After all, the function of a designer baby industry, like the one in the "Genetic Pressure" series, wouldn't necessarily be limited to eliminating genetic diseases; it could also work to increase the occurrence of "desirable" traits. </p><p>If the industry did that, it'd effectively signal that the <em>opposites of those traits are undesirable. </em>As the International Bioethics Committee <a href="https://academic.oup.com/jlb/advance-article/doi/10.1093/jlb/lsaa006/5841599#204481018" target="_blank" rel="noopener noreferrer">wrote</a>, this would "jeopardize the inherent and therefore equal dignity of all human beings and renew eugenics, disguised as the fulfillment of the wish for a better, improved life."</p><p><em>"Genetic Pressure Volume I: Baby Steps"</em><em> by Eugene Clark is <a href="http://bigth.ink/38VhJn3" target="_blank">available now.</a></em></p>
It's hard to stop looking back and forth between these faces and the busts they came from.
- A quarantine project gone wild produces the possibly realistic faces of ancient Roman rulers.
- A designer worked with a machine learning app to produce the images.
- It's impossible to know if they're accurate, but they sure look plausible.
How the Roman emperors got faced<a href="https://payload.cargocollective.com/1/6/201108/14127595/2K-ENGLISH-24x36-Educational_v8_WATERMARKED_2000.jpg" ><img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNDQ2NDk2MS9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYyOTUzMzIxMX0.OwHMrgKu4pzu0eCsmOUjybdkTcSlJpL_uWDCF2djRfc/img.jpg?width=980" id="775ca" class="rm-shortcode" data-rm-shortcode-id="436000b6976931b8320313478c624c82" data-rm-shortcode-name="rebelmouse-image" alt="lineup of emperor faces" data-width="1440" data-height="963" /></a>
Credit: Daniel Voshart<p>Voshart's imaginings began with an AI/neural-net program called <a href="https://www.artbreeder.com" target="_blank">Artbreeder</a>. The freemium online app intelligently generates new images from existing ones and can combine multiple images into…well, who knows. It's addictive — people have so far used it to generate nearly 72.7 million images, says the site — and it's easy to see how Voshart fell down the rabbit hole.</p><p>The Roman emperor project began with Voshart feeding Artbreeder images of 800 busts. Obviously, not all busts have weathered the centuries equally. Voshart told <a href="https://www.livescience.com/ai-roman-emperor-portraits.html" target="_blank" rel="noopener noreferrer">Live Science</a>, "There is a rule of thumb in computer programming called 'garbage in garbage out,' and it applies to Artbreeder. A well-lit, well-sculpted bust with little damage and standard face features is going to be quite easy to get a result." Fortunately, there were multiple busts for some of the emperors, and different angles of busts captured in different photographs.</p><p>For the renderings Artbreeder produced, each face required some 15-16 hours of additional input from Voshart, who was left to deduce/guess such details as hair and skin coloring, though in many cases, an individual's features suggested likely pigmentations. Voshart was also aided by written descriptions of some of the rulers.</p><p>There's no way to know for sure how frequently Voshart's guesses hit their marks. It is obviously the case, though, that his interpretations look incredibly plausible when you compare one of his emperors to the sculpture(s) from which it was derived.</p><p>For an in-depth description of Voshart's process, check out his posts on <a href="https://medium.com/@voshart/photoreal-roman-emperor-project-236be7f06c8f" target="_blank">Medium</a> or on his <a href="https://voshart.com/ROMAN-EMPEROR-PROJECT" target="_blank" rel="noopener noreferrer">website</a>.</p><p>It's fascinating to feel like you're face-to-face with these ancient and sometimes notorious figures. Here are two examples, along with some of what we think we know about the men behind the faces.</p>
Caligula<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNDQ2NDk4Mi9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTY3MzQ1NTE5NX0.LiTmhPQlygl9Fa9lxay8PFPCSqShv4ELxbBRFkOW_qM/img.jpg?width=980" id="7bae0" class="rm-shortcode" data-rm-shortcode-id="ce795c554490fe0a36a8714b86f55b16" data-rm-shortcode-name="rebelmouse-image" data-width="992" data-height="558" />
One of numerous sculptures of Caligula, left
Nero<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNDQ2NTAwMC9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTY1NTQ2ODU0NX0.AgYuQZzRQCanqehSI5UeakpxU8fwLagMc_POH7xB3-M/img.jpg?width=980" id="a8825" class="rm-shortcode" data-rm-shortcode-id="9e0593d79c591c97af4bd70f3423885e" data-rm-shortcode-name="rebelmouse-image" data-width="992" data-height="558" />
One of numerous sculptures of Nero, left
A popular and longstanding wave of thought in psychology and psychotherapy is that diagnosis is not relevant for practitioners in those fields.
Scientists regenerate damaged spinal cord nerve fibers with designer protein, helping paralyzed mice walk again.
- Researchers from Germany use a designer protein to treat spinal cord damage in mice.
- The procedure employs gene therapy to regenerate damaged nerve fibers that carry signals to and from the brain.
- The scientists aim to eventually apply the technique to humans.