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What Keeps Aubrey de Grey Up At Night
Aubrey de Grey, PhD, is Chairman and Chief Science Officer of the Methuselah Foundation. The core of his research is the identification of all forms of cellular and molecular damage whose accumulation contributes to human aging, and the design of interventions to remove, repair, replace, or render harmless all such damage so as to arrest or even reverse the biological aging process. He has published extensively on these and other areas of gerontology in the scientific literature, and is also Editor-in-Chief of the high-impact journal Rejuvenation Research, the only peer-reviewed academic journal focusing on intervention in aging.
Question: What keeps you up at night?
Aubrey de Grey: I’m not a worrier actually. I figure I’ve got an extraordinarily privileged life. I’ve been able to get into a position of making a very substantial difference to the world’s biggest problem, and you know as a scientist as someone who likes working on hard problems you can’t get much better than that, so I’m pretty content with my life.
Question: Are you worried about dying?
Aubrey de Grey: I don’t really think about my personal fate except in so far I don’t want to anytime soon because I want to carry on making a big difference to the world and also because I’m enjoying my life, but my own life span, my own mortality, doesn’t really figure in my calculations. I mainly think about the effect that I’m having on the world in general, and that’s really for mathematical reasons because, let’s face it, the therapies that I’m working to hasten are gonna happen sometime anyway. What I’m doing is getting them to happen sooner, and if we ask how much difference am I personally making, then you know even in extraordinarily optimistic scenario I’m certainly not making more than 10 years difference to the date at which these therapies are going to emerge, so that means that I’m not making more than 10 or 15 percent difference to my probability of making the cut right.
Now it’s very easy to get worked up about 10 or 15 percent, and I could say the same if I were thinking about my wife for example or my mother or whatever, but if I’m thinking about people in general, then I can think about the fact that 100,000 a day are dying in a horrible way from the thing called aging. And if I were to bring forward the defeat of aging even by one day, that would be 30 World Trade Centers of lives that I’m saving, and it’s very easy to get worked up about that.
Recorded on: October 2, 2009
Aubrey de Grey is not a worrier—he is content to try to make a difference with his life.
Sallie Krawcheck and Bob Kulhan will be talking money, jobs, and how the pandemic will disproportionally affect women's finances.
Health officials in China reported that a man was infected with bubonic plague, the infectious disease that caused the Black Death.
- The case was reported in the city of Bayannur, which has issued a level-three plague prevention warning.
- Modern antibiotics can effectively treat bubonic plague, which spreads mainly by fleas.
- Chinese health officials are also monitoring a newly discovered type of swine flu that has the potential to develop into a pandemic virus.
Bacteria under microscope
needpix.com<p>Today, bubonic plague can be treated effectively with antibiotics.</p><p style="margin-left: 20px;">"Unlike in the 14th century, we now have an understanding of how this disease is transmitted," Dr. Shanthi Kappagoda, an infectious disease physician at Stanford Health Care, told <a href="https://www.healthline.com/health-news/seriously-dont-worry-about-the-plague#Heres-how-the-plague-spreads" target="_blank">Healthline</a>. "We know how to prevent it — avoid handling sick or dead animals in areas where there is transmission. We are also able to treat patients who are infected with effective antibiotics, and can give antibiotics to people who may have been exposed to the bacteria [and] prevent them [from] getting sick."</p>
This plague patient is displaying a swollen, ruptured inguinal lymph node, or buboe.
Centers for Disease Control and Prevention<p>Still, hundreds of people develop bubonic plague every year. In the U.S., a handful of cases occur annually, particularly in New Mexico, Arizona and Colorado, <a href="https://www.cdc.gov/plague/faq/index.html" target="_blank">where habitats allow the bacteria to spread more easily among wild rodent populations</a>. But these cases are very rare, mainly because you need to be in close contact with rodents in order to get infected. And though plague can spread from human to human, this <a href="https://www.healthline.com/health-news/seriously-dont-worry-about-the-plague#Heres-how-the-plague-spreads" target="_blank">only occurs with pneumonic plague</a>, and transmission is also rare.</p>
A new swine flu in China<p>Last week, researchers in China also reported another public health concern: a new virus that has "all the essential hallmarks" of a pandemic virus.<br></p><p>In a paper published in the <a href="https://www.pnas.org/content/early/2020/06/23/1921186117" target="_blank">Proceedings of the National Academy of Sciences</a>, researchers say the virus was discovered in pigs in China, and it descended from the H1N1 virus, commonly called "swine flu." That virus was able to transmit from human to human, and it killed an estimated 151,700 to 575,400 people worldwide from 2009 to 2010, according to the Centers for Disease Control and Prevention.</p>There's no evidence showing that the new virus can spread from person to person. But the researchers did find that 10 percent of swine workers had been infected by the virus, called G4 reassortant EA H1N1. This level of infectivity raises concerns, because it "greatly enhances the opportunity for virus adaptation in humans and raises concerns for the possible generation of pandemic viruses," the researchers wrote.
The word "learning" opens up space for more people, places, and ideas.
- The terms 'education' and 'learning' are often used interchangeably, but there is a cultural connotation to the former that can be limiting. Education naturally links to schooling, which is only one form of learning.
- Gregg Behr, founder and co-chair of Remake Learning, believes that this small word shift opens up the possibilities in terms of how and where learning can happen. It also becomes a more inclusive practice, welcoming in a larger, more diverse group of thinkers.
- Post-COVID, the way we think about what learning looks like will inevitably change, so it's crucial to adjust and begin building the necessary support systems today.
Scientists uncovered the secrets of what drove some of the world's last remaining woolly mammoths to extinction.
Every summer, children on the Alaskan island of St Paul cool down in Lake Hill, a crater lake in an extinct volcano – unaware of the mysteries that lie beneath.
The coronavirus pandemic has brought out the perception of selfishness among many.
- Selfish behavior has been analyzed by philosophers and psychologists for centuries.
- New research shows people may be wired for altruistic behavior and get more benefits from it.
- Times of crisis tend to increase self-centered acts.