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The Genetic Basis of Risk-Seeking
Dr. Marvin Zuckerman is Professor Emeritus at the University of Delaware. His research involves the sensation-seeking trait, affect assessment, and its role in risk-taking behaviors and its biological bases. A fellow of the American Psychological Society, a fellow of its Division of Personality and Social Psychology and a diplomate of the American Board of Examiners in Professional Psychology-Clinical Psychology, Zuckerman has served as president of the International Society for the Study of Individual Differences. He also is a board member of the Delaware Council on Gambling Problems and the Delaware Addictions Coalition.
He is the author of more than 200 articles and book chapters and several books, including Vulnerability to Psychopathology: A Biosocial Model, Psychobiology of Personality and Behavioral Expression and Biosocial Bases of Personality. He also serves on the editorial board of Personality and Individual Differences.
Zuckerman received his bachelor's and doctoral degrees from New York University.
Question: What is sensory deprivation?
Marvin Zuckerman: Sensory deprivation is where you put people in dark, sound-proof rooms, or water tanks. People were becoming aware that we needed sensation stimulation, variation stimulation almost as much as we need food and water and so forth. It’s a basic need. Deprivation of this kind of stimulation led to some very uncomfortable states.
So we asked, is there a personality trait that some people need more stimulation or more variety or intensity of stimulation than others? That’s when we developed our first sensation-seeking scale. Subsequently that expanded and became the main focus of my research. We were surprised by how many things were affected by this trait, sensation-seeking. Then we got interested in the biological basis, the genetic biological basis and here again, we had some very interesting findings pointing to the fact that this is a very fundamental trait with biological roots.
Question: How much of the sensation-seeking trait is determined genetically?
Marvin Zuckerman: Well this is determined from twin studies called Biometrics of Behavior Genetics actually. Using these twin studies we initially found that roughly 60% inheritability. In heritability is the proportion of the variance in a trait that is determined by genetics. We discovered there was 60% -- which is very high for a personality trait which generally runs between 30% and 50%. So, 60% is high for a personality trait. Well, it’s higher for intelligence and some other traits. This was established not only using twins raised together but twins raised apart showing that it wasn’t due to the fact of sharing a stimulating environment let’s say. There’s an environmental aspect of the remaining 40%, **** error of measurement, but some of it is due to environment. But it’s not the shared; what we called the shared environment, shared in the family. It’s due to the non-shared environment which means your friends, peers or your unique life experiences that you don’t share with other people in your family.
Question: Was sensation-seeking a factor in human evolution?
Marvin Zuckerman: Well we can surmise that particularly since a particular gene has been found to be related to sensation-seeking, a dopamine receptor gene. So that means it’s been there a long time. Well, actually they estimate though that it’s been – not all evolution maybe 50,000-100,000 years old in our species, this particular gene but there may be genes that are older even. But you see this in other – the point is, you see what I call emalogues of sensation-seeking behavior in other species. In fact, a lot of my work is compared sensation-seeking expressions exploration approach to novelty in other species. And I explored to the extent that do they have the same biological roots in humans and in other species. So, in that sense we look at evolution – we have a modern test of evolution when you can find something that exists in humans in earlier species, particularly primates ****, but also even in rats, when you can find this and it’s linked to the same biological indicators in both humans and other animals. That indicates it has an evolutionary history rather it’s more than merely an analogy. Well this looks like what we do. But it’s more than that, it’s the fact that it looks like sensation-seeking and has the same biological roots.
Question: Does the presence of this behavior vary across ages?
Marvin Zuckerman: I would say the age differences are somewhat larger if you’re looking at the extremes. I would say like of about sixty-sixty-five a male would have half the sensation-seeking score that he had when he was in his late-teens and early-twenties. So that's pretty much of a decline. The male-female differences are constant across age, but perhaps not as large. I want to talk about sex differences in traits. We’re always talking about a lot of overlap or talking about population differences. People always say, “I know someone who’s female, but has a very high sensation-seeking.” Of course, there’s variation within both genders. Just the overall population difference is different.
A clinical psychologist explains the biological basis of novelty-seeking behavior and its importance in evolutionary history.
Chronic irregular sleep in children was associated with psychotic experiences in adolescence, according to a recent study out of the University of Birmingham's School of Psychology.
A time for sleep<div class="rm-shortcode" data-media_id="Mt29uUqI" data-player_id="FvQKszTI" data-rm-shortcode-id="931343dee3c02121445e51e94ba22446"> <div id="botr_Mt29uUqI_FvQKszTI_div" class="jwplayer-media" data-jwplayer-video-src="https://content.jwplatform.com/players/Mt29uUqI-FvQKszTI.js"> <img src="https://cdn.jwplayer.com/thumbs/Mt29uUqI-1920.jpg" class="jwplayer-media-preview" /> </div> <script src="https://content.jwplatform.com/players/Mt29uUqI-FvQKszTI.js"></script> </div> <p>Previous studies had already suggested a link between persistent nightmares in childhood and psychosis and borderline personality disorder (BPD) by adolescence, but researchers at the University of Birmingham's School of Psychology wanted to see if a similar connection existed between these mental disorders and other childhood behavioral sleep problems.</p><p>To do this, they scoured data from the Avon Longitudinal Study of Parents and Children, a longitudinal cohort study that followed approximately 14,000 children born in Avon, England, in the early 1990s. The study followed the children for more than 13 years. During that time, mothers filled out questionnaires asking about the children's lives. Factors looked at included housing, parenting, nutrition, physical health, mental wellbeing, environmental exposures, and so on. </p><p>The cohort study inquired about sleep routines, sleep duration, and awakening frequency when the children were 6, 18, and 30 months old, and then again at 3.5, 4.8, and 5.8 years. It also assessed mental health in adolescence using semi-structured interviews, such as the Psychosis-Like Symptom Interview.</p><p>"We know that adolescence is a key developmental period to study the onset of many mental disorders, including psychosis or BPD. This is because of particular brain and hormonal changes which occur at this stage," <a href="https://www.birmingham.ac.uk/staff/profiles/psychology/marwaha-steven.aspx" target="_blank">Steven Marwaha</a>, professor of psychiatry at Birmingham and senior author on the study, <a href="https://www.sciencedaily.com/releases/2020/07/200701125431.htm" target="_blank">said in a release</a>. "Sleep may be one of the most important underlying factors—and it's one that we can influence with effective, early interventions, so it's important that we understand these links."</p><p>After compiling the data, the researchers discovered an association between children with irregular sleeping patterns and teenagers with <a href="https://www.mind.org.uk/information-support/types-of-mental-health-problems/psychosis/about-psychosis/" target="_blank">psychotic experiences</a>—that is, episodes when the person perceives reality differently than those around them. Even when depression at 10 years old was considered as a mediating factor, their findings still suggested "a specific pathway between these childhood sleep problems and adolescent psychotic experiences." </p><p>Toddlers with shorter nighttime sleep duration and late bedtimes were likewise associated with a <a href="https://www.nimh.nih.gov/health/topics/borderline-personality-disorder/index.shtml" target="_blank">borderline personality disorder</a>—a disorder marked by a pattern of varying moods, self-images, and behaviors—in their teenage years. Depression at age 10 did not mediate this particular association, suggesting a separate and more specific pathway. </p>
A more restful tomorrow<p>While the sample size was large and mental health was assessed with a validated interview, there nevertheless remain limitations to this data. For starters, sleep habits were based on mothers' reports. Because they came from memory, versus a more direct observation method such as actigraphy, these data may be prone to imperfect recollection and reporting error. There are also many confounders that could be secretly nudging the results, such as family conditions, prenatal medicines, and a host of environmental factors. Finally, <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024884/#:~:text=Sleep%20difficulties%20in%20youth%20with,fear%20of%20dark%20%5B13%5D." target="_blank">the relationship between sleep problems and mental disorders</a> is both complex and two-way.</p><p>As such, the study shows an association between poor childhood sleep later mental disorders but does not prove a causal link. Parents need not worry that a string of nightmares or the eternal struggle settle into bed will be the first ingredients in a witches' brew of debilitating mental disorders. The goal of the study, the researchers point out, is not to create undue worry but improve our ability to recognize the signs of at-risk children and deliver necessary interventions earlier.</p><p>"The results of this study could have important implications for helping practitioners identify children who might be at higher risk for psychotic experiences or BPD symptoms in adolescence, and potentially lead to the design of more effectively targeted sleep or psychological interventions to prevent the onset or attenuate these mental disorders," Isabel Morales-Muñoz, the study's lead researcher, <a href="https://www.healio.com/news/psychiatry/20200702/childhood-sleep-problems-linked-to-adolescent-psychosis-borderline-personality-disorder#:~:text=Sleep%20problems%20during%20early%20childhood,study%20published%20in%20JAMA%20Psychiatry." target="_blank">told Healio Psychiatry</a><u>.</u></p><p>If a parent reading this is worried that their child's sleep patterns are deleterious, the take away should not be despair over an unyielding fate. It should be to seek professional help as soon as possible to begin improving sleep duration and quality. Even if you aren't worried, it's worth remembering that childhood experiences lay the foundation for a lifetime of salubrious sleeping habits. It's so much more than beauty rest.</p>
Are we genetically inclined for superstition or just fearful of the truth?
- From secret societies to faked moon landings, one thing that humanity seems to have an endless supply of is conspiracy theories. In this compilation, physicist Michio Kaku, science communicator Bill Nye, psychologist Sarah Rose Cavanagh, skeptic Michael Shermer, and actor and playwright John Cameron Mitchell consider the nature of truth and why some groups believe the things they do.
- "I think there's a gene for superstition, a gene for hearsay, a gene for magic, a gene for magical thinking," argues Kaku. The theoretical physicist says that science goes against "natural thinking," and that the superstition gene persists because, one out of ten times, it actually worked and saved us.
- Other theories shared include the idea of cognitive dissonance, the dangerous power of fear to inhibit critical thinking, and Hollywood's romanticization of conspiracies. Because conspiracy theories are so diverse and multifaceted, combating them has not been an easy task for science.
Construction of the $500 billion dollar tech city-state of the future is moving ahead.
- The futuristic megacity Neom is being built in Saudi Arabia.
- The city will be fully automated, leading in health, education and quality of life.
- It will feature an artificial moon, cloud seeding, robotic gladiators and flying taxis.
The Red Sea area where Neom will be built:
Saudi Arabia Plans Futuristic City, "Neom" (Full Promotional Video)<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="c646d528d230c1bf66c75422bc4ccf6f"><iframe type="lazy-iframe" data-runner-src="https://www.youtube.com/embed/N53DzL3_BHA?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span>
A growing body of research suggests COVID-19 can cause serious neurological problems.
- The new study seeks to track the health of 50,000 people who have tested positive for COVID-19.
- The study aims to explore whether the disease causes cognitive impairment and other conditions.
- Recent research suggests that COVID-19 can, directly or indirectly, cause brain dysfunction, strokes, nerve damage and other neurological problems.
Brain images of a patient with acute demyelinating encephalomyelitis.
COVID-19 and the brain<p>A growing body of research reveals alarming neurological complications among COVID-19 patients. On Wednesday, for example, researchers from University College London published a <a href="https://academic.oup.com/brain/article/doi/10.1093/brain/awaa240/5868408" target="_blank">study</a> in the journal Brain that describes how some patients have suffered temporary brain dysfunction, strokes, nerve damage, and other neurological problems concurrent with COVID-19.</p><p>Some patients suffered brain inflammation as a result of a rare disease called acute disseminated encephalomyelitis, which can cause numbness, seizures, and confusion. One patient in the study even hallucinated monkeys and lions in her home.</p>
Photo by Mario Tama/Getty Images<p>A separate study published in the <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198407/" target="_blank">Journal of Clinical Neuroscience</a> notes that some COVID-19 patients have also suffered neurological complications like impaired consciousness and acute cerebrovascular disease. The study notes that past viruses like MERS and SARS also seemed to cause neurological problems.</p><p>A troubling finding among this growing body of research is that some patients seem to suffer neurological damage even when respiratory symptoms aren't obvious. Additionally, scientists aren't sure whether damage from the disease will be permanent.</p><p style="margin-left: 20px;">"Given that the disease has only been around for a matter of months, we might not yet know what long-term damage COVID-19 can cause," Dr. Ross Paterson, joint first author of the University College London study, said in a <a href="https://www.eurekalert.org/pub_releases/2020-07/ucl-iid070620.php" target="_blank">press release</a>. "Doctors needs to be aware of possible neurological effects, as early diagnosis can improve patient outcomes."</p><p>If you've been diagnosed with COVID-19 and want to enroll in the study, visit <a href="https://www.cambridgebrainsciences.com/studies/covid-brain-study" target="_blank">cambridgebrainsciences.com/studies/covid-brain-study</a>.</p>