Is there a clash of civilizations?
Reza Aslan is an internationally renowned writer, commentator, professor, producer, and scholar of religions. His books, including his #1 New York Times Bestseller, Zealot: The Life and Times of Jesus of Nazareth, have been translated into dozens of languages around the world. He is also a recipient of the prestigious James Joyce Award. His newest book God: A Human History (2017) is out now.
Aslan’s first book, International Bestseller No god but God: The Origins, Evolution, and Future of Islam, has been translated into seventeen languages, and was named one of the 100 most important books of the last decade by Blackwell Publishers. He is also the author of Beyond Fundamentalism: Confronting Religious Extremism in a Globalized Age (originally titled How to Win a Cosmic War), as well as editor of two volumes: Tablet and Pen: Literary Landscapes from the Modern Middle East, and Muslims and Jews in America: Commonalties, Contentions, and Complexities.
In 2006, Aslan co-founded BoomGen Studios—the premiere entertainment brand for creative content from and about the Middle East—which has provided an array of targeted services ranging from strategic messaging to grassroots marketing to publicity and social media outreach, to producers, studios, and filmmakers—including Jon Stewart’s Rosewater, Netflix’s The Square, Disney’s Aladdin on Broadway and Prince of Persia: The Sands of Time, The Weinstein Company’s Miral, Discovery and TLC’s All American Muslim, and National Geographic’s Amreeka.
Aslan’s degrees include a Bachelor of Arts in Religious Studies from Santa Clara University (Major focus: New Testament; Minor: Greek), a Master of Theological Studies from Harvard University (Major focus: History of Religions), a PhD in the Sociology of Religions from the University of California, Santa Barbara, and a Master of Fine Arts from the University of Iowa, where he was named the Truman Capote Fellow in Fiction.
Aslan is a tenured Professor of Creative Writing at the University of California, Riverside and serves on the board of trustees for the Chicago Theological Seminary and The Yale Humanist Community, which supports atheists, agnostics, and humanists at home and abroad.
Reza Aslan: My question, I think, to not just the Muslim world but to the western world – in fact to everybody on every side of this so called clash of civilizations that we are supposed to be embroiled in right now – would be, “What is the civilization that you are talking about? What do you think of when you say western civilization or Islamic civilization? And how is it that your view of civilization is so drastically different from the other’s view of civilization, that there is this inevitable clash that we are supposed to be seeing?” This sort of inherent division between these two societies that for, you know, that have no choice but to be on this collision course with each other? “What is it that you think your civilization is that makes it so different from the civilization of the other?” And I think that in answering that question both people in the Muslim world and the west will come to realize how absurd the idea of this division is. Yes we have different ideas, different ethnicities, different traditions and social customs; but are we in a war between social customs? Are we in a war of identities? I hope not. I think the idea that civilization is something that is how we define ourselves as a people – which is I think quite common amongst most people – I think that idea has to be debummed. There is something that connects us to each other that is far more visceral and far more deep-seeded than civilization is, and that is just the human condition.
Recorded On: 7/5/07
Aslan challenges the West and Muslims to define this clash so that we can see that we are not all that different.
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- Researchers at the Yale School of Medicine successfully restored some functions to pig brains that had been dead for hours.
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- The research raises many ethical questions and puts to the test our current understanding of death.
The image of an undead brain coming back to live again is the stuff of science fiction. Not just any science fiction, specifically B-grade sci fi. What instantly springs to mind is the black-and-white horrors of films like Fiend Without a Face. Bad acting. Plastic monstrosities. Visible strings. And a spinal cord that, for some reason, is also a tentacle?
But like any good science fiction, it's only a matter of time before some manner of it seeps into our reality. This week's Nature published the findings of researchers who managed to restore function to pigs' brains that were clinically dead. At least, what we once thought of as dead.
What's dead may never die, it seems
The researchers did not hail from House Greyjoy — "What is dead may never die" — but came largely from the Yale School of Medicine. They connected 32 pig brains to a system called BrainEx. BrainEx is an artificial perfusion system — that is, a system that takes over the functions normally regulated by the organ. The pigs had been killed four hours earlier at a U.S. Department of Agriculture slaughterhouse; their brains completely removed from the skulls.
BrainEx pumped an experiment solution into the brain that essentially mimic blood flow. It brought oxygen and nutrients to the tissues, giving brain cells the resources to begin many normal functions. The cells began consuming and metabolizing sugars. The brains' immune systems kicked in. Neuron samples could carry an electrical signal. Some brain cells even responded to drugs.
The researchers have managed to keep some brains alive for up to 36 hours, and currently do not know if BrainEx can have sustained the brains longer. "It is conceivable we are just preventing the inevitable, and the brain won't be able to recover," said Nenad Sestan, Yale neuroscientist and the lead researcher.
As a control, other brains received either a fake solution or no solution at all. None revived brain activity and deteriorated as normal.
The researchers hope the technology can enhance our ability to study the brain and its cellular functions. One of the main avenues of such studies would be brain disorders and diseases. This could point the way to developing new of treatments for the likes of brain injuries, Alzheimer's, Huntington's, and neurodegenerative conditions.
"This is an extraordinary and very promising breakthrough for neuroscience. It immediately offers a much better model for studying the human brain, which is extraordinarily important, given the vast amount of human suffering from diseases of the mind [and] brain," Nita Farahany, the bioethicists at the Duke University School of Law who wrote the study's commentary, told National Geographic.
An ethical gray matter
Before anyone gets an Island of Dr. Moreau vibe, it's worth noting that the brains did not approach neural activity anywhere near consciousness.
The BrainEx solution contained chemicals that prevented neurons from firing. To be extra cautious, the researchers also monitored the brains for any such activity and were prepared to administer an anesthetic should they have seen signs of consciousness.
Even so, the research signals a massive debate to come regarding medical ethics and our definition of death.
Most countries define death, clinically speaking, as the irreversible loss of brain or circulatory function. This definition was already at odds with some folk- and value-centric understandings, but where do we go if it becomes possible to reverse clinical death with artificial perfusion?
"This is wild," Jonathan Moreno, a bioethicist at the University of Pennsylvania, told the New York Times. "If ever there was an issue that merited big public deliberation on the ethics of science and medicine, this is one."
One possible consequence involves organ donations. Some European countries require emergency responders to use a process that preserves organs when they cannot resuscitate a person. They continue to pump blood throughout the body, but use a "thoracic aortic occlusion balloon" to prevent that blood from reaching the brain.
The system is already controversial because it raises concerns about what caused the patient's death. But what happens when brain death becomes readily reversible? Stuart Younger, a bioethicist at Case Western Reserve University, told Nature that if BrainEx were to become widely available, it could shrink the pool of eligible donors.
"There's a potential conflict here between the interests of potential donors — who might not even be donors — and people who are waiting for organs," he said.
It will be a while before such experiments go anywhere near human subjects. A more immediate ethical question relates to how such experiments harm animal subjects.
Ethical review boards evaluate research protocols and can reject any that causes undue pain, suffering, or distress. Since dead animals feel no pain, suffer no trauma, they are typically approved as subjects. But how do such boards make a judgement regarding the suffering of a "cellularly active" brain? The distress of a partially alive brain?
The dilemma is unprecedented.
Setting new boundaries
Another science fiction story that comes to mind when discussing this story is, of course, Frankenstein. As Farahany told National Geographic: "It is definitely has [sic] a good science-fiction element to it, and it is restoring cellular function where we previously thought impossible. But to have Frankenstein, you need some degree of consciousness, some 'there' there. [The researchers] did not recover any form of consciousness in this study, and it is still unclear if we ever could. But we are one step closer to that possibility."
She's right. The researchers undertook their research for the betterment of humanity, and we may one day reap some unimaginable medical benefits from it. The ethical questions, however, remain as unsettling as the stories they remind us of.
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