from the world's big
How diversity melts away our biases, and technology is the great equalizer
The most revelatory answers in life come from complex, diverse populations. Technology can open our eyes to what we're missing and destroy our subconscious biases in one fell swoop.
Beau Lotto is a professor of neuroscience, previously at University College London and now at the University of London, and a Visiting Scholar at New York University. His work focuses on the biological, computational and psychological mechanisms of perception. He has conducted and presented research on human and bumblebee perception and behavior for more than 25 years, and his interest in education, business and the arts has led him into entrepreneurship and engaging the public with science. In 2001, Beau founded the Lab of Misfits, a neuro-design studio that was resident for two years at London's Science Museum and most recently at Viacom in New York. The lab's experimental studio approach aims to deepen our understanding of human nature, advance personal and social well-being through research that places the public at the centre of the process of discovery, and create unique programmes of engagement that span the boundaries between people, disciplines and institutions. Originally from Seattle, with degrees from UC Berkeley and Edinburgh Medical School, he now lives in Oxford and New York.
Beau Lotto is a professor of neuroscience, previously at University College London and now at the University of London, and a Visiting Scholar at New York University.
His work focuses on the biological, computational and psychological mechanisms of perception. He has conducted and presented research on human and bumblebee perception and behavior for more than 25 years, and his interest in education, business and the arts has led him into entrepreneurship and engaging the public with science.
In 2001, Beau founded the Lab of Misfits, a neuro-design studio that was resident for two years at London's Science Museum and most recently at Viacom in New York. The lab's experimental studio approach aims to deepen our understanding of human nature, advance personal and social well-being through research that places the public at the centre of the process of discovery, and create unique programmes of engagement that span the boundaries between people, disciplines and institutions. Originally from Seattle, with degrees from UC Berkeley and Edinburgh Medical School, he now lives in Oxford and New York.
Beau Lotto: If the process of seeing differently is the process of first and foremost having awareness of the fact that everything you do has an assumption, figuring out what those are—and by the way, the best person to reveal your own assumptions to you is not yourself, it’s usually someone else, hence the power of diversity, the importance of diversity. Because not only does that diversity reveal your own assumptions to you, but it can also complex-ify your assumptions. Because we know from complex systems theory that the best solution is most likely to exist within a complex search space, not a simple search space, simply because of statistics. So whereas a simple search space is more adaptable, it’s more easy to adapt, it’s less likely to contain the best solution.
So what we really want is a diversity of possibilities, a diversity of assumptions—which diverse groups, for instance, enable. But also diverse experience. So one of the best ways to diversify, complex-ify your search space, your assumptions, is through experience. And one of the great ways to do that is actually through technology. So we think about technology, and most of our technologies are good technologies. But what defines a great technology? What is a transformative technology?
The good technologies are the ones that enable us to do what we can already do faster, easier, more efficiently. And that’s because so much of our society focuses on efficiency. It’s about maximizing performance. We’re great engineers but we’re crap philosophers. We’re very good at making things more efficient, but that’s only one side of innovation.We also need the other side of innovation, which is creativity. And so the best technologies are the ones—in my view—that make the invisible visible. They enable us to see things that we could never have seen before. They create assumptions. They expand our space of assumptions. We typically think, of course, of digital technologies, but we can also think of the telescope, the microscope. In fact we can even think of the sail.
So the sail was in one sense invented on the Nile, because the currents the wind go in opposite directions. So you could sail up current and then you could float back down. But what the sail enables us to do was to travel, which meant we could see different ecologies, different cultures. Which, when approached in an open way, enabled us to not only challenge but expand our assumptions, because we would have incorporated their biases into our own. So you could view it in a different way. The best transformative technologies enable us to travel. But not just travel physically. Travel in our minds. So a book, writing, this also leads onto things like augmented reality and even virtual reality. So in our case we’ve actually done experiments and created a whole platform in augmented reality to see if we can explore how the brain makes meaning by engaging with a new layer in the world. Not to replace the real world but to expand it.
Another example is the feelSpace belt. So what this was was a belt that was, in fact, a belt, right. It went around your waist, and effectively what it did is it vibrated in the direction of north, which effectively gave people the ability to see what they couldn’t see before. They made the invisible visible. And what happened is that people would consciously make reference—well initially they just felt a vibration—and then they started incorporating it into their movement and into their navigation consciously.But eventually it became unconscious to the point that when they actually removed the belt they felt insecure. So effectively they were almost turning people into birds, who are able to detect magnetic north in their migrations. And the brain was able to adapt and redefine normality based on this new information that it was getting. But not just the data, the meaning of the data by physically engaging with the world. Because only in that sense did it come to literally make sense.
Being close-minded is like being in handcuffs—you can't let yourself out, someone has to pop the lock for you. That's why diversity matters, says neuroscientist Beau Lotto. Meeting others unlocks our perception. We spend our lives in the cuffs of our own assumptions, but encountering people who think and act differently teaches us so much about ourselves, and what we may have been blind to up until that point. If creativity is the act of thinking differently, then surrounding ourselves with a diversity of people, with diverse life experiences, can radically expand our field of possibility. Technology is another way to do that, says Lotto, and if you leaf through history it's apparent that the most radical technological breakthroughs are the ones that have expanded our perceptions: the printing press gave us books, which let us see other people's stories; the telescope gave us the universe, which gave us curiosity (and humility); the ship gave us mobility, which gave us cultural and material trade. Technology enables us "to see things that we could never have seen before," and it makes the invisible visible, says Lotto. The more layers of meaning we can detect—whether through diversity or technology—the better we're able to think, innovate, and connect. Beau Lotto's new book is Deviate: The Science of Seeing Differently.
Sallie Krawcheck and Bob Kulhan will be talking money, jobs, and how the pandemic will disproportionally affect women's finances.
Vaccines find more success in development than any other kind of drug, but have been relatively neglected in recent decades.
Vaccines are more likely to get through clinical trials than any other type of drug — but have been given relatively little pharmaceutical industry support during the last two decades, according to a new study by MIT scholars.
An article in Journal of Bioethical Inquiry raises questions about the goal of these advocacy groups.
- Two-thirds of American consumer advocacy groups are funded by pharmaceutical companies.
- The authors of an article in Journal of Bioethical Inquiry say this compromises their advocacy.
- Groups like the National Alliance on Mental Illness act more like lobbyists than patient advocates.
The Corruption That Brought Prozac to Market — Robert Whitaker, Journalist<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="bea9cff2b25efc18b663a011a679ba16"><iframe type="lazy-iframe" data-runner-src="https://www.youtube.com/embed/UyaJExxFPAE?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span><p>Consumer-oriented groups gained steam over the ensuing decades. Their efforts helped inspire the 1938 Food, Drug, and Cosmetic Act after over 100 people (mostly children) died from a sanctioned drug, Sulfanilamide. If not for the hard work of these advocates, this case might have been overlooked.</p><p>Early efforts also focused on the food industry, which was increasingly using chemical preservatives. The origin of Consumer Reports can be found in the consumer advocacy movement. Both the food and drug industries were getting a free pass to experiment on citizens with few repercussions.</p><p>These movements provided a social foundation for important advocacy work in the second half of the century. Female-led groups evolved to focus on women's reproductive rights, AIDS, and mental health. As the authors write, these groups struck a balance between working <em>with</em> and <em>against</em> current trends. Sometimes you need to craft legislation with officials; at other times, you have to rage against the machine with everything you've got. </p><p>Advocacy marked an important turning point in public health (and culture in general). These groups were tired of placating to a medical model that treated the male body as the standard. This wasn't limited to anatomy. As I <a href="https://bigthink.com/coronavirus/pandemic-warnings-rp-eddy" target="_self">wrote about last week</a>, a high-profile 1970s-era conference about the role of women on Wall St featured no women on stage. You can imagine what reproductive health looked like during that time. </p><p>Advocacy groups made real impact in public health. Then the money began pouring in. </p><p style="margin-left: 20px;">"These groups were funded largely by individual donations with some foundation support, but in the late 1980s, newer women's health groups moved to professionalize, effectively splitting the women's health movement."</p><p>A number of groups resist corporate ties to this day, such as the National Women's Heath Network and Breast Cancer Action. Too often, however, groups argue that their existence depends on corporate funding. This can lead to uncomfortable compromises. </p><p>An estimated two-thirds of patient advocacy groups in America accept funds from the pharmaceutical industry. Pharma companies gave <a href="https://link.springer.com/content/pdf/10.1007/s11673-019-09956-8.pdf" target="_blank">at least $116 million</a> to such groups in 2015 alone.</p><p>For example, over a three-year period, the National Alliance on Mental Illness (NAMI), which was founded by two mothers whose sons suffered from schizophrenia, received nearly $12 million from 18 pharmaceutical companies. The largest donor was Prozac manufacturer, Eli Lilly. By 2008, three-quarters of NAMI's budget was funded by the pharmaceutical industry. It gets worse:</p><p style="margin-left: 20px;">"An Eli Lilly executive was even 'on loan' to NAMI, paid by Eli Lilly, while he worked out of the NAMI office on 'strategic planning.'"</p>
A customer waiting for his medication at the Headache Bar in a pharmacy in Sydney, Australia. Among the items on sale are 'Paigees with Chlorophyll' and Alka Seltzer on tap.
Photo by Dennis Rowe/BIPs/Getty Images<p>This influx of cash skews public understanding of drugs. It also influences advocates to overlook real problems caused by pharmaceutical interventions, especially when it comes to mental health.<br></p><p>For a real-world example, consider how Xanax came to market. As journalist Robert Whitaker <a href="https://www.youtube.com/watch?v=2e829xdb4AA" target="_blank">explains</a>, an <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1463502/?page=1" target="_blank">initial study</a> was conducted to determine efficacy in treating panic attacks. After four weeks, Xanax was outperforming placebo, which is common with benzodiazepines over short-term usage. But it wasn't a four-week study; it was a 14-week study.</p><p>At the end of eight weeks, there was no difference in efficacy between Xanax and placebo.</p><p>At the conclusion of the study after 14 weeks, the placebo outperformed Xanax. By a lot.</p><p>Why is Xanax still prescribed for panic attacks? Because the pharmaceutical company, Upjohn, only published the four-week data. The 14-week data was not in its favor. Nearly forty years later, over <a href="https://www.statista.com/statistics/781816/alprazolam-sodium-prescriptions-number-in-the-us/" target="_blank">25 million</a> Americans receive a prescription despite its <a href="https://drugabuse.com/xanax/effects-use/" target="_blank">long list</a> of side effects and addictive profile. </p><p>As the authors note, many consumers are not aware of how advocacy groups are funded.</p><p style="margin-left: 20px;">"An international study of groups in the United States, United Kingdom, Australia, Canada, and South Africa found that the extent of relationships with industry was inadequately disclosed in websites that addressed ten health conditions: cancer, heart disease, diabetes, asthma, cystic fibrosis, epilepsy, depression, Parkinson's disease, osteoporosis, and rheumatoid arthritis."</p><p>That's a tangled web of relationships. Pharmaceutical industry funding negatively impacts the work advocacy groups should be focused on: protecting us. NAMI, for example, claims that as a "natural ally" to the pharmaceutical industry, it helps consumers access "all scientifically proven treatments." When the industry ignores evidence of long-term damage caused by its treatments, you have to wonder what's being advocated. </p><p>Although, as the authors conclude, that question is easy to answer. </p><p style="margin-left: 20px;">"Instead of drawing insights from patient experience to set organizational agendas and challenge industry agendas, today's groups are silent on high prices and drug harms, oppose efforts to regulate these basic rights, and demand access to drugs that challenge the safety and effectiveness."</p><p><span></span>--</p><p><em>Stay in touch with Derek on <a href="http://www.twitter.com/derekberes" target="_blank">Twitter</a>, <a href="https://www.facebook.com/DerekBeresdotcom" target="_blank">Facebook</a> and <a href="https://derekberes.substack.com/" target="_blank">Substack</a>. His next book is</em> "<em>Hero's Dose: The Case For Psychedelics in Ritual and Therapy."</em></p>
Health officials in China reported that a man was infected with bubonic plague, the infectious disease that caused the Black Death.
- The case was reported in the city of Bayannur, which has issued a level-three plague prevention warning.
- Modern antibiotics can effectively treat bubonic plague, which spreads mainly by fleas.
- Chinese health officials are also monitoring a newly discovered type of swine flu that has the potential to develop into a pandemic virus.
Bacteria under microscope
needpix.com<p>Today, bubonic plague can be treated effectively with antibiotics.</p><p style="margin-left: 20px;">"Unlike in the 14th century, we now have an understanding of how this disease is transmitted," Dr. Shanthi Kappagoda, an infectious disease physician at Stanford Health Care, told <a href="https://www.healthline.com/health-news/seriously-dont-worry-about-the-plague#Heres-how-the-plague-spreads" target="_blank">Healthline</a>. "We know how to prevent it — avoid handling sick or dead animals in areas where there is transmission. We are also able to treat patients who are infected with effective antibiotics, and can give antibiotics to people who may have been exposed to the bacteria [and] prevent them [from] getting sick."</p>
This plague patient is displaying a swollen, ruptured inguinal lymph node, or buboe.
Centers for Disease Control and Prevention<p>Still, hundreds of people develop bubonic plague every year. In the U.S., a handful of cases occur annually, particularly in New Mexico, Arizona and Colorado, <a href="https://www.cdc.gov/plague/faq/index.html" target="_blank">where habitats allow the bacteria to spread more easily among wild rodent populations</a>. But these cases are very rare, mainly because you need to be in close contact with rodents in order to get infected. And though plague can spread from human to human, this <a href="https://www.healthline.com/health-news/seriously-dont-worry-about-the-plague#Heres-how-the-plague-spreads" target="_blank">only occurs with pneumonic plague</a>, and transmission is also rare.</p>
A new swine flu in China<p>Last week, researchers in China also reported another public health concern: a new virus that has "all the essential hallmarks" of a pandemic virus.<br></p><p>In a paper published in the <a href="https://www.pnas.org/content/early/2020/06/23/1921186117" target="_blank">Proceedings of the National Academy of Sciences</a>, researchers say the virus was discovered in pigs in China, and it descended from the H1N1 virus, commonly called "swine flu." That virus was able to transmit from human to human, and it killed an estimated 151,700 to 575,400 people worldwide from 2009 to 2010, according to the Centers for Disease Control and Prevention.</p>There's no evidence showing that the new virus can spread from person to person. But the researchers did find that 10 percent of swine workers had been infected by the virus, called G4 reassortant EA H1N1. This level of infectivity raises concerns, because it "greatly enhances the opportunity for virus adaptation in humans and raises concerns for the possible generation of pandemic viruses," the researchers wrote.
Want help raising your kids? Spend more time at church, says new study.
- Religious people tend to have more children than secular people, but why remains unknown.
- A new study suggests that the social circles provided by regular church going make raising kids easier.
- Conversely, having a large secular social group made women less likely to have children.