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Active ingredient in Roundup found in 95% of studied beers and wines
The controversial herbicide is everywhere, apparently.
- U.S. PIRG tested 20 beers and wines, including organics, and found Roundup's active ingredient in almost all of them.
- A jury on August 2018 awarded a non-Hodgkin's lymphoma victim $289 million in Roundup damages.
- Bayer/Monsanto says Roundup is totally safe. Others disagree.
If there were a Hall of Fame for chemicals people worry about, it's likely that Monsanto's weedkiller Roundup would sit near or at the top of that dark pantheon.
It's been linked to cancers, diabetes, Alzheimer's, Parkinson's, liver disease, kidney disease, birth defects and more. On top of that, many believe it's what's been killing off the world's bees, vital participants in the human food chain.
Now, research just published in February by the education group U.S. PIRG, illumines that the active ingredient in Roundup, glyphosate, may be impacting humans routinely via our drinking habits. In the group's study, 20 beers and wines, including some organic beverages, were tested for the presence of glyphosate. It was found in 19 of them.
What are you drinking?
The only drink tested that contained no glyphosate was Peak Beer Organic IPA. The comestible with the highest amount of glyphosate? Sutter Home Merlot. The 19 are shown below with the parts per billion (ppb) of glyphosate they contained.
- Tsingtao Beer: 49.7 ppb
- Coors Light: 31.1 ppb
- Miller Lite: 29.8 ppb
- Budweiser: 27.0 ppb
- Corona Extra: 25.1 ppb
- Heineken: 20.9 ppb
- Guinness Draught: 20.3 ppb
- Stella Artois: 18.7 ppb
- Ace Perry Hard Cider: 14.5 ppb
- Sierra Nevada Pale Ale: 11.8 ppb
- New Belgium Fat Tire Amber Ale: 11.2 ppb
- Sam Adams New England IPA: 11.0 ppb
- Stella Artois Cidre: 9.1 ppb
- Samuel Smith's Organic Lager: 5.7 ppb
- Sutter Home Merlot: 51.4 ppb
- Beringer Founders Estates Moscato: 42.6 ppb
- Barefoot Cabernet Sauvignon: 36.3 ppb
- Inkarri Malbec, Certified Organic: 5.3 ppb
- Frey Organic Natural White: 4.8 ppb
Should such small amounts be of concern? Maybe. The report says:
"While these levels of glyphosate are below EPA risk tolerances for beverages, it is possible that even low levels of glyphosate can be problematic. For example, in one study, scientists found that 1 part per trillion of glyphosate has the potential to stimulate the growth of breast cancer cells and disrupt the endocrine system."
Roundup on trial
The EPA says glyphosate is safe up to 2 milligrams per kilogram of body weight per day, and Bayer, who now owns Monsanto, claims that its safety for consumption by humans has been proven by years of research. However, the World Health Organization's International Agency for Research on Cancer, among many others, disagrees, and considers glyphosate a potential human carcinogen. In addition, a new study finds that people exposed to glyphosate are 41 percent more likely to develop non-Hodgkin's lymphoma. France has banned Roundup's use, and other European nations are said to be considering their own bans on the weedkiller.
There's also a trial underway in federal court in San Francisco that consolidates 760 of the U.S.'s 9,300 Roundup cases into a single suit against Bayer by Edwin Hardeman, a California resident. It's viewed as a test case.
Hardeman is currently in remission from non-Hodgkin's after having used Roundup extensively beginning in the 1980s to control poison oak and weeds on his property. He was diagnosed with lymphoma at age 66 in 2015. Bayer asserts that Hardeman has other conditions — his age and history of Hepatitis C — that more likely led to his illness; in any event, their lawyers say, non-Hodgkin's is often idiopathic anyway.
The judge has divided the case into two phases. In the first, jurors are to determine whether Roundup caused Hardeman's illness based on scientific evidence presented in court. Unfortunately, the jurors are not scientists, and one may wonder just how reasonable an endeavor this really is — it's likely to come down to the persuasiveness of evidence that's inevitably cherry-picked by the opposing legal teams to support their case.
If the jurors find Roundup is the illness's cause, a second phase can commence to assess responsibility. The plaintiffs have called this bifurcation "unfair," specifically because they believe their scientific evidence involves Monsanto's repression of research damaging to claims of glyphosate's safety, and the judge is not allowing any such supposedly off-topic submissions.
In August 2018, a more conventional courtroom approach led to a finding that Monsanto was to blame for school groundskeeper Dewayne Johnson's non-Hodgkin's lymphoma because they failed to warn its users of Roundup's potential risk as a cancer-causing product. That jury awarded Johnson $289 million in damages. The amount was later reduced to $78 million.
There's enough Roundup sprayed every year to spray nearly half a pound of glyphosate on every cultivated acre of land in the world, says U.S. PIRG.
A little extra kick in your beverage
This isn't the first time glyphosate's been found to have made its way into adult beverages. In Germany in 2016, the Munich Environmental Institute found it in every single sample they tested, including beers from independent brewers. A study in Latvia found the same thing. Using glyphosate directly on barley — beer's primary ingredient — is illegal in Germany, so it's most likely that the soil in which the crop was grown had been previously exposed to Roundup.
It's unlikely nine laypeople in a San Francisco courtroom will definitely answer the question of glyphosate's safety. It's clear that questions surrounding this ubiquitous weedkiller remain, Bayer's assertions notwithstanding.
U.S. PIRG concludes its report with a recommendation:
"Based on our findings, glyphosate is found in most beers and wine sold in the U.S. Due to glyphosate's many health risks and its ubiquitous nature in our food, water and alcohol, the use of glyphosate in the U.S. should be banned unless and until it can be proven safe."
Scientists are using bioelectronic medicine to treat inflammatory diseases, an approach that capitalizes on the ancient "hardwiring" of the nervous system.
- Bioelectronic medicine is an emerging field that focuses on manipulating the nervous system to treat diseases.
- Clinical studies show that using electronic devices to stimulate the vagus nerve is effective at treating inflammatory diseases like rheumatoid arthritis.
- Although it's not yet approved by the US Food and Drug Administration, vagus nerve stimulation may also prove effective at treating other diseases like cancer, diabetes and depression.
The nervous system’s ancient reflexes<p>You accidentally place your hand on a hot stove. Almost instantaneously, your hand withdraws.</p><p>What triggered your hand to move? The answer is <em>not</em> that you consciously decided the stove was hot and you should move your hand. Rather, it was a reflex: Skin receptors on your hand sent nerve impulses to the spinal cord, which ultimately sent back motor neurons that caused your hand to move away. This all occurred before your "conscious brain" realized what happened.</p><p>Similarly, the nervous system has reflexes that protect individual cells in the body.</p><p>"The nervous system evolved because we need to respond to stimuli in the environment," said Dr. Tracey. "Neural signals don't come from the brain down first. Instead, when something happens in the environment, our peripheral nervous system senses it and sends a signal to the central nervous system, which comprises the brain and spinal cord. And then the nervous system responds to correct the problem."</p><p>So, what if scientists could "hack" into the nervous system, manipulating the electrical activity in the nervous system to control molecular processes and produce desirable outcomes? That's the chief goal of bioelectronic medicine.</p><p>"There are billions of neurons in the body that interact with almost every cell in the body, and at each of those nerve endings, molecular signals control molecular mechanisms that can be defined and mapped, and potentially put under control," Dr. Tracey said in a <a href="https://www.youtube.com/watch?v=AJH9KsMKi5M" target="_blank">TED Talk</a>.</p><p>"Many of these mechanisms are also involved in important diseases, like cancer, Alzheimer's, diabetes, hypertension and shock. It's very plausible that finding neural signals to control those mechanisms will hold promises for devices replacing some of today's medication for those diseases."</p><p>How can scientists hack the nervous system? For years, researchers in the field of bioelectronic medicine have zeroed in on the longest cranial nerve in the body: the vagus nerve.</p>
The vagus nerve<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNTYyOTM5OC9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTY0NTIwNzk0NX0.UCy-3UNpomb3DQZMhyOw_SQG4ThwACXW_rMnc9mLAe8/img.jpg?width=1245&coordinates=0%2C0%2C0%2C0&height=700" id="09add" class="rm-shortcode" data-rm-shortcode-id="f38dbfbbfe470ad85a3b023dd5083557" data-rm-shortcode-name="rebelmouse-image" data-width="1245" data-height="700" />
Electrical signals, seen here in a synapse, travel along the vagus nerve to trigger an inflammatory response.
Credit: Adobe Stock via solvod<p>The vagus nerve ("vagus" meaning "wandering" in Latin) comprises two nerve branches that stretch from the brainstem down to the chest and abdomen, where nerve fibers connect to organs. Electrical signals constantly travel up and down the vagus nerve, facilitating communication between the brain and other parts of the body.</p><p>One aspect of this back-and-forth communication is inflammation. When the immune system detects injury or attack, it automatically triggers an inflammatory response, which helps heal injuries and fend off invaders. But when not deployed properly, inflammation can become excessive, exacerbating the original problem and potentially contributing to diseases.</p><p>In 2002, Dr. Tracey and his colleagues discovered that the nervous system plays a key role in monitoring and modifying inflammation. This occurs through a process called the <a href="https://www.nature.com/articles/nature01321" target="_blank" rel="noopener noreferrer">inflammatory reflex</a>. In simple terms, it works like this: When the nervous system detects inflammatory stimuli, it reflexively (and subconsciously) deploys electrical signals through the vagus nerve that trigger anti-inflammatory molecular processes.</p><p>In rodent experiments, Dr. Tracey and his colleagues observed that electrical signals traveling through the vagus nerve control TNF, a protein that, in excess, causes inflammation. These electrical signals travel through the vagus nerve to the spleen. There, electrical signals are converted to chemical signals, triggering a molecular process that ultimately makes TNF, which exacerbates conditions like rheumatoid arthritis.</p><p>The incredible chain reaction of the inflammatory reflex was observed by Dr. Tracey and his colleagues in greater detail through rodent experiments. When inflammatory stimuli are detected, the nervous system sends electrical signals that travel through the vagus nerve to the spleen. There, the electrical signals are converted to chemical signals, which trigger the spleen to create a white blood cell called a T cell, which then creates a neurotransmitter called acetylcholine. The acetylcholine interacts with macrophages, which are a specific type of white blood cell that creates TNF, a protein that, in excess, causes inflammation. At that point, the acetylcholine triggers the macrophages to stop overproducing TNF – or inflammation.</p><p>Experiments showed that when a specific part of the body is inflamed, specific fibers within the vagus nerve start firing. Dr. Tracey and his colleagues were able to map these relationships. More importantly, they were able to stimulate specific parts of the vagus nerve to "shut off" inflammation.</p><p>What's more, clinical trials show that vagus nerve stimulation not only "shuts off" inflammation, but also triggers the production of cells that promote healing.</p><p>"In animal experiments, we understand how this works," Dr. Tracey said. "And now we have clinical trials showing that the human response is what's predicted by the lab experiments. Many scientific thresholds have been crossed in the clinic and the lab. We're literally at the point of regulatory steps and stages, and then marketing and distribution before this idea takes off."<br></p>
The future of bioelectronic medicine<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNTYxMDYxMy9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYzNjQwOTExNH0.uBY1TnEs_kv9Dal7zmA_i9L7T0wnIuf9gGtdRXcNNxo/img.jpg?width=980" id="8b5b2" class="rm-shortcode" data-rm-shortcode-id="c005e615e5f23c2817483862354d2cc4" data-rm-shortcode-name="rebelmouse-image" data-width="2000" data-height="1125" />
Vagus nerve stimulation can already treat Crohn's disease and other inflammatory diseases. In the future, it may also be used to treat cancer, diabetes, and depression.
Credit: Adobe Stock via Maridav<p>Vagus nerve stimulation is currently awaiting approval by the US Food and Drug Administration, but so far, it's proven safe and effective in clinical trials on humans. Dr. Tracey said vagus nerve stimulation could become a common treatment for a wide range of diseases, including cancer, Alzheimer's, diabetes, hypertension, shock, depression and diabetes.</p><p>"To the extent that inflammation is the problem in the disease, then stopping inflammation or suppressing the inflammation with vagus nerve stimulation or bioelectronic approaches will be beneficial and therapeutic," he said.</p><p>Receiving vagus nerve stimulation would require having an electronic device, about the size of lima bean, surgically implanted in your neck during a 30-minute procedure. A couple of weeks later, you'd visit, say, your rheumatologist, who would activate the device and determine the right dosage. The stimulation would take a few minutes each day, and it'd likely be unnoticeable.</p><p>But the most revolutionary aspect of bioelectronic medicine, according to Dr. Tracey, is that approaches like vagus nerve stimulation wouldn't come with harmful and potentially deadly side effects, as many pharmaceutical drugs currently do.</p><p>"A device on a nerve is not going to have systemic side effects on the body like taking a steroid does," Dr. Tracey said. "It's a powerful concept that, frankly, scientists are quite accepting of—it's actually quite amazing. But the idea of adopting this into practice is going to take another 10 or 20 years, because it's hard for physicians, who've spent their lives writing prescriptions for pills or injections, that a computer chip can replace the drug."</p><p>But patients could also play a role in advancing bioelectronic medicine.</p><p>"There's a huge demand in this patient cohort for something better than they're taking now," Dr. Tracey said. "Patients don't want to take a drug with a black-box warning, costs $100,000 a year and works half the time."</p><p>Michael Dowling, president and CEO of Northwell Health, elaborated:</p><p>"Why would patients pursue a drug regimen when they could opt for a few electronic pulses? Is it possible that treatments like this, pulses through electronic devices, could replace some drugs in the coming years as preferred treatments? Tracey believes it is, and that is perhaps why the pharmaceutical industry closely follows his work."</p><p>Over the long term, bioelectronic approaches are unlikely to completely replace pharmaceutical drugs, but they could replace many, or at least be used as supplemental treatments.</p><p>Dr. Tracey is optimistic about the future of the field.</p><p>"It's going to spawn a huge new industry that will rival the pharmaceutical industry in the next 50 years," he said. "This is no longer just a startup industry. [...] It's going to be very interesting to see the explosive growth that's going to occur."</p>
The first rule of Vulture Club: stay out of Portugal.
So you're a vulture, riding the thermals that rise up over Iberia. Your way of life is ancient, ruled by needs and instincts that are way older than the human civilization that has overtaken the peninsula below, and the entire planet.
"The Expanse" is the best vision I've ever seen of a space-faring future that may be just a few generations away.
- Want three reasons why that headline is justified? Characters and acting, universe building, and science.
- For those who don't know, "The Expanse" is a series that's run on SyFy and Amazon Prime set about 200 years in the future in a mostly settled solar system with three waring factions: Earth, Mars, and Belters.
- No other show I know of manages to use real science so adeptly in the service of its story and its grand universe building.
Credit: "The Expanse" / Syfy<p>Now, I get it if you don't agree with me. I love "Star Trek" and I thought "Battlestar Galactica" (the new one) was amazing and I do adore "The Mandalorian". They are all fun and important and worth watching and thinking about. And maybe you love them more than anything else. But when you sum up the acting, the universe building, and the use of real science where it matters, I think nothing can beat "The Expanse". And with a <a href="https://www.rottentomatoes.com/tv/the_expanse" target="_blank">Rotten Tomato</a> average rating of 93%, I'm clearly not the only one who feels this way.</p><p>Best.</p><p>Show.</p><p>Ever. </p>
Contrary to what some might think, the brain is a very plastic organ.
As with many other physicians, recommending physical activity to patients was just a doctor chore for me – until a few years ago. That was because I myself was not very active.