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Hallucinogens: A Way to Soothe Mental Illness, Even Get Ahead
Psychedelics came en vogue in the 1960s and since then have been maligned as inducing psychosis. Today, some evidence suggests that tiny doses of these drugs may be useful for curing psychological disorders such as depression, PTSD, and social anxiety, among others. But more research is needed and there are hurdles to overcome.
Psychedelics have been with humans for over two millennia. Ethnobotanist Terence McKenna’s “stoned ape theory,” postulates that the development of language may have started with our ancient ancestors taking psychedelics, as they have the propensity to make one talkative and interested in sounds.
Shamans and medicine men of Africa and the America’s have used hallucinogens for thousands of years in religious practices—to divining prophecy, as a rite of passage, and more. These have been so paramount to certain cultures that Native Americans in the West have won court cases to be allowed to continue their use in rituals. Some anthropologists say these ancient cultures respect for such substances, within the confines of ritual, have safeguarded their users from addiction, and allowed for great insights. As for ancient civilizations, it is thought that the soma beverage of the Vedas, the sacred texts of Hinduism, contained psilocybin or “magic” mushrooms as an ingredient.
In Western society how hallucinogens were regarded has swung back and forth like a pendulum. Ergot is a parasitic fungus that grows on rye and rye bread which can cause hallucinations. During the Black Death and again in the 16th and 17th centuries, bouts of insanity, which were sometimes interpreted as witchery or demonic possession, was often caused by ergot poisoning. In Medieval times and during the Renaissance, ergot victims suffered from what was known as St. Vitus dance, or the Dance of Death. The latter can be found throughout medieval iconography. Some historians have linked certain weather conditions and the likelihood of ergot with the witch hunts of Europe and colonial America—most famously in Salem.
The Salem witch trials may have been from accidental ergot poisoning.
Fast forward to the 20th century, and we have Swiss chemist Albert Hoffman who in 1938 created a synthetic version of ergotamine that within a few decades would be all the rage with young hippies. He accidently discovered lysergic acid diethylamide (LSD), trying to find a drug that stimulated breathing and circulation. While experimenting on himself, he found that he experienced incredible and sometimes horrific hallucinations. Soon the U.S. government became interested. From 1953 to 1964 the CIA conducted a series of LSD experiments as part of Project MK Ultra. In this program, American citizens were given different biological and chemical agents, often without their knowledge. The documents surrounding this program were destroyed before a 1973 Senate investigation came underway.
The program included Secret LSD experiments which took place at 30 universities. Author Ken Kesey was one such subject. Later on, he experimented with mescaline while conducting his nighttime duties at a psychiatric institution, at which he worked, and wrote One Flew Over the Cuckoo’s Nest. As for the CIA experiments, many speculate that they were to see whether or not a person would be more susceptible to hypnosis, in order to brain-wash them into becoming a CIA assassin. Project MK Ultra became the basis of The Manchurian Candidate and George Clooney’s character in Men Who Stare at Goats.
The counterculture movement of the 1960’s gleaned onto psychedelics, and many artists over the years admit to being inspired by them. Two camps quickly formed. Those in the quite, contemplative Eastern aesthetic flocked to Dr. Timothy Leary, who took LSD with groups of followers to accentuate meditation. A more ecstatic group admired Ken Kesey and his merry pranksters, whose antics are laid bare in, The Electric Kool-Aid Acid Test. Concurrently, in the 1950’s thru the early 1970’s, medical experiments using psychedelics to treat addiction and mental illness were considered cutting-edge.
LSD and other psychedelics were thought mind-expanding in the 1960’s. That attitude may be back.
The 1980’s brought the War on Drugs and so the end of such research. Some say the baby boomers who embraced psychedelics in the 60’s, didn’t want their kids doing them. But now that they are older and have fond memories of their former years, public opinion on has once again shifted. In the last two decades or so, a resurgence of research in LSD and psilocybin—the active ingredient in magic mushrooms, has occurred.
A 2006 study out of the University of Arizona found that psilocybin helped reduce the symptoms of obsessive-compulsive disorder (OCD). Research at both UCLA and NYU have helped relieve the anxiety of cancer patients using psilocybin. A small 2014 study found that LSD reduced feelings of anxiety permanently from those suffering anxiety disorder. A British study last year found that psilocybin decreased depression symptoms without any serious side effects. Other studies have shown remarkable results.
In one, published in the Journal of Psychopharmacology, 10 alcoholics given psilocybin. It reduced cravings even months after treatment. In a 2014 Johns Hopkins study 15 smokers were given psilocybin. 12 out of 15 remained smoke free at the six month follow-up. There is some evidence that the hallucinogenic drink Ayahuasca can help with anxiety and depression, according to Evan Wood. He is a psychiatric researcher at the University of British Columbia. Also MDMA, the active ingredient in Ecstasy, may help ease the symptoms of PTSD.
Wood says psychedelics allow an individual to feel a spiritual or mystical experience. They often have profound realizations about themselves, and it is through this that they are able to transform, and drastically change their behavior. Wood says the standard procedure for conditions like depression or anxiety, or even addiction is certain prescription drugs. These are considered lifelong chronic conditions. With psychedelics however, one dose is effective long-term. Though Drug War propaganda would have you believe that such drugs induce permanent insanity, a recent review in the Canadian Medical Association Journal found no lasting effects.
Dr. Timothy Leary proponent of LSD in the 1960’s.
Some patients today, who struggle with anxiety, depression, or even things like migraines, are taking matters into their own hands and microdosing. This is not “tripping” but taking a tiny sliver of the recommended dose in order to get an uplifting effect, without any significant side effects. No hallucinations are induced. Psychologist James Fadiman is a pioneering researcher in psychedelics who came up with microdosing. To do it with LSD for instance, one would take one-tenth of a normal dose, around 10-20 micrograms, rather than the 100-200 micrograms needed to “trip.” The microdose would be ingested once every four days in the morning. Just take it and go about your day.
Some patients are doing it to alleviate anxiety or depression. They believe this type of treatment is better than the current pharmacological approaches. A writer for the website Refinery 29 recently wrote about microdosing psilocybin mushrooms for migraines. She takes 1/100t of a dose, about 0.2-0.5 grams. A growing number of psychedelic enthusiasts are even microdosing to get creative ideas or solve problems in the work space. Wouldn’t the hippies be horrified? Rolling Stone recently uncovered this trend among young professionals in Silicon Valley.
Still, one must understand that currently there is limited research and most of the studies have been small. Another problem studying such things as LSD, such a low dose in the system is hard to detect, and so it’s effects difficult to objectively deduce. According to Fadiman, when coupled with yoga or meditation, troubled patients say with depression or anxiety sleep better, eat better, and generally feel better after taking psychedelics. Fadiman has gathered hundreds of testimonials, and is aiming for an FDA approved study. Even with some promising data in hand, most medical professionals say that hallucinogenics are dangerous and highly illegal.
Even so, with the opioid addiction epidemic raging, and the prevalence of depression and other serious disorders, many believe that microdosing psychedelics may be the future of mental health and addiction remediation, and the medical community need only shed their prejudices and catch up.
To learn more about the so-called psychedelic renaissance click here:
Northwell Health is using insights from website traffic to forecast COVID-19 hospitalizations two weeks in the future.
- The machine-learning algorithm works by analyzing the online behavior of visitors to the Northwell Health website and comparing that data to future COVID-19 hospitalizations.
- The tool, which uses anonymized data, has so far predicted hospitalizations with an accuracy rate of 80 percent.
- Machine-learning tools are helping health-care professionals worldwide better constrain and treat COVID-19.
The value of forecasting<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNTA0Njk2OC9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYyMzM2NDQzOH0.rid9regiDaKczCCKBsu7wrHkNQ64Vz_XcOEZIzAhzgM/img.jpg?width=980" id="2bb93" class="rm-shortcode" data-rm-shortcode-id="31345afbdf2bd408fd3e9f31520c445a" data-rm-shortcode-name="rebelmouse-image" data-width="1546" data-height="1056" />
Northwell emergency departments use the dashboard to monitor in real time.
Credit: Northwell Health<p>One unique benefit of forecasting COVID-19 hospitalizations is that it allows health systems to better prepare, manage and allocate resources. For example, if the tool forecasted a surge in COVID-19 hospitalizations in two weeks, Northwell Health could begin:</p><ul><li>Making space for an influx of patients</li><li>Moving personal protective equipment to where it's most needed</li><li>Strategically allocating staff during the predicted surge</li><li>Increasing the number of tests offered to asymptomatic patients</li></ul><p>The health-care field is increasingly using machine learning. It's already helping doctors develop <a href="https://care.diabetesjournals.org/content/early/2020/06/09/dc19-1870" target="_blank">personalized care plans for diabetes patients</a>, improving cancer screening techniques, and enabling mental health professionals to better predict which patients are at <a href="https://healthitanalytics.com/news/ehr-data-fuels-accurate-predictive-analytics-for-suicide-risk" target="_blank" rel="noopener noreferrer">elevated risk of suicide</a>, to name a few applications.</p><p>Health systems around the world have already begun exploring how <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315944/" target="_blank" rel="noopener noreferrer">machine learning can help battle the pandemic</a>, including better COVID-19 screening, diagnosis, contact tracing, and drug and vaccine development.</p><p>Cruzen said these kinds of tools represent a shift in how health systems can tackle a wide variety of problems.</p><p>"Health care has always used the past to predict the future, but not in this mathematical way," Cruzen said. "I think [Northwell Health's new predictive tool] really is a great first example of how we should be attacking a lot of things as we go forward."</p>
Making machine-learning tools openly accessible<p>Northwell Health has made its predictive tool <a href="https://github.com/northwell-health/covid-web-data-predictor" target="_blank">available for free</a> to any health system that wishes to utilize it.</p><p>"COVID is everybody's problem, and I think developing tools that can be used to help others is sort of why people go into health care," Dr. Cruzen said. "It was really consistent with our mission."</p><p>Open collaboration is something the world's governments and health systems should be striving for during the pandemic, said Michael Dowling, Northwell Health's president and CEO.</p><p>"Whenever you develop anything and somebody else gets it, they improve it and they continue to make it better," Dowling said. "As a country, we lack data. I believe very, very strongly that we should have been and should be now working with other countries, including China, including the European Union, including England and others to figure out how to develop a health surveillance system so you can anticipate way in advance when these things are going to occur."</p><p>In all, Northwell Health has treated more than 112,000 COVID patients. During the pandemic, Dowling said he's seen an outpouring of goodwill, collaboration, and sacrifice from the community and the tens of thousands of staff who work across Northwell.</p><p>"COVID has changed our perspective on everything—and not just those of us in health care, because it has disrupted everybody's life," Dowling said. "It has demonstrated the value of community, how we help one another."</p>
Scientists used CT scanning and 3D-printing technology to re-create the voice of Nesyamun, an ancient Egyptian priest.
- Scientists printed a 3D replica of the vocal tract of Nesyamun, an Egyptian priest whose mummified corpse has been on display in the UK for two centuries.
- With the help of an electronic device, the reproduced voice is able to "speak" a vowel noise.
- The team behind the "Voices of the Past" project suggest reproducing ancient voices could make museum experiences more dynamic.
Howard et al.<p style="margin-left: 20px;">"While this approach has wide implications for heritage management/museum display, its relevance conforms exactly to the ancient Egyptians' fundamental belief that 'to speak the name of the dead is to make them live again'," they wrote in a <a href="https://www.nature.com/articles/s41598-019-56316-y#Fig3" target="_blank">paper</a> published in Nature Scientific Reports. "Given Nesyamun's stated desire to have his voice heard in the afterlife in order to live forever, the fulfilment of his beliefs through the synthesis of his vocal function allows us to make direct contact with ancient Egypt by listening to a sound from a vocal tract that has not been heard for over 3000 years, preserved through mummification and now restored through this new technique."</p>
Connecting modern people with history<p>It's not the first time scientists have "re-created" an ancient human's voice. In 2016, for example, Italian researchers used software to <a href="https://www.smithsonianmag.com/smart-news/hear-recreated-voice-otzi-iceman-180960570/" target="_blank">reconstruct the voice of Ötzi,</a> an iceman who was discovered in 1991 and is thought to have died more than 5,000 years ago. But the "Voices of the Past" project is different, the researchers note, because Nesyamun's mummified corpse is especially well preserved.</p><p style="margin-left: 20px;">"It was particularly suited, given its age and preservation [of its soft tissues], which is unusual," Howard told <em><a href="https://www.livescience.com/amp/ancient-egypt-mummy-voice-reconstructed.html" target="_blank">Live Science</a>.</em></p><p>As to whether Nesyamun's reconstructed voice will ever be able to speak complete sentences, Howard told <em><a href="https://abcnews.go.com/Weird/wireStory/ancient-voice-scientists-recreate-sound-egyptian-mummy-68482015" target="_blank">The Associated Press</a>, </em>that it's "something that is being worked on, so it will be possible one day."</p><p>John Schofield, an archaeologist at the University of York, said that reproducing voices from history can make museum experiences "more multidimensional."</p><p style="margin-left: 20px;">"There is nothing more personal than someone's voice," he told <em>The Associated Press.</em> "So we think that hearing a voice from so long ago will be an unforgettable experience, making heritage places like Karnak, Nesyamun's temple, come alive."</p>
A new study proposes mysterious axions may be found in X-rays coming from a cluster of neutron stars.
Are Axions Dark Matter?<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="5e35ce24a5b17102bfce5ae6aecc7c14"><iframe type="lazy-iframe" data-runner-src="https://www.youtube.com/embed/e7yXqF32Yvw?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span>
New research suggests you can't fake your emotional state to improve your work life — you have to feel it.
What is deep acting?<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNTQ1NDk2OS9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYxNTY5MzA0Nn0._s7aP25Es1CInq51pbzGrUj3GtOIRWBHZxCBFnbyXY8/img.jpg?width=1245&coordinates=333%2C-1%2C333%2C-1&height=700" id="ddf09" class="rm-shortcode" data-rm-shortcode-id="9dc42c4d6a8e372ad7b72907b46ecd3f" data-rm-shortcode-name="rebelmouse-image" data-width="1245" data-height="700" />
Arlie Russell Hochschild (pictured) laid out the concept of emotional labor in her 1983 book, "The Managed Heart."
Credit: Wikimedia Commons<p>Deep and surface acting are the principal components of emotional labor, a buzz phrase you have likely seen flitting about the Twittersphere. Today, "<a href="https://www.bbc.co.uk/bbcthree/article/5ea9f140-f722-4214-bb57-8b84f9418a7e" target="_blank">emotional labor</a>" has been adopted by groups as diverse as family counselors, academic feminists, and corporate CEOs, and each has redefined it with a patented spin. But while the phrase has splintered into a smorgasbord of pop-psychological arguments, its initial usage was more specific.</p><p>First coined by sociologist Arlie Russell Hochschild in her 1983 book, "<a href="https://www.ucpress.edu/book/9780520272941/the-managed-heart" target="_blank">The Managed Heart</a>," emotional labor describes the work we do to regulate our emotions on the job. Hochschild's go-to example is the flight attendant, who is tasked with being "nicer than natural" to enhance the customer experience. While at work, flight attendants are expected to smile and be exceedingly helpful even if they are wrestling with personal issues, the passengers are rude, and that one kid just upchucked down the center aisle. Hochschild's counterpart to the flight attendant is the bill collector, who must instead be "nastier than natural."</p><p>Such personas may serve an organization's mission or commercial interests, but if they cause emotional dissonance, they can potentially lead to high emotional costs for the employee—bringing us back to deep and surface acting.</p><p>Deep acting is the process by which people modify their emotions to match their expected role. Deep actors still encounter the negative emotions, but they devise ways to <a href="http://www.selfinjury.bctr.cornell.edu/perch/resources/what-is-emotion-regulationsinfo-brief.pdf" target="_blank">regulate those emotions</a> and return to the desired state. Flight attendants may modify their internal state by talking through harsh emotions (say, with a coworker), focusing on life's benefits (next stop Paris!), physically expressing their desired emotion (smiling and deep breaths), or recontextualizing an inauspicious situation (not the kid's fault he got sick).</p><p>Conversely, surface acting occurs when employees display ersatz emotions to match those expected by their role. These actors are the waiters who smile despite being crushed by the stress of a dinner rush. They are the CEOs who wear a confident swagger despite feelings of inauthenticity. And they are the bouncers who must maintain a steely edge despite humming show tunes in their heart of hearts.</p><p>As we'll see in the research, surface acting can degrade our mental well-being. This deterioration can be especially true of people who must contend with negative emotions or situations inside while displaying an elated mood outside. Hochschild argues such emotional labor can lead to exhaustion and self-estrangement—that is, surface actors erect a bulwark against anger, fear, and stress, but that disconnect estranges them from the emotions that allow them to connect with others and live fulfilling lives.</p>
Don't fake it till you make it<p>Most studies on emotional labor have focused on customer service for the obvious reason that such jobs prescribe emotional states—service with a smile or, if you're in the bouncing business, a scowl. But <a href="https://eller.arizona.edu/people/allison-s-gabriel" target="_blank">Allison Gabriel</a>, associate professor of management and organizations at the University of Arizona's Eller College of Management, wanted to explore how employees used emotional labor strategies in their intra-office interactions and which strategies proved most beneficial.</p><p>"What we wanted to know is whether people choose to engage in emotion regulation when interacting with their co-workers, why they choose to regulate their emotions if there is no formal rule requiring them to do so, and what benefits, if any, they get out of this effort," Gabriel said in <a href="https://www.sciencedaily.com/releases/2020/01/200117162703.htm" target="_blank">a press release</a>.</p><p>Across three studies, she and her colleagues surveyed more than 2,500 full-time employees on their emotional regulation with coworkers. The survey asked participants to agree or disagree with statements such as "I try to experience the emotions that I show to my coworkers" or "I fake a good mood when interacting with my coworkers." Other statements gauged the outcomes of such strategies—for example, "I feel emotionally drained at work." Participants were drawn from industries as varied as education, engineering, and financial services.</p><p>The results, <a href="https://psycnet.apa.org/doiLanding?doi=10.1037%2Fapl0000473" target="_blank" rel="noopener noreferrer">published in the Journal of Applied Psychology</a>, revealed four different emotional strategies. "Deep actors" engaged in high levels of deep acting; "low actors" leaned more heavily on surface acting. Meanwhile, "non-actors" engaged in negligible amounts of emotional labor, while "regulators" switched between both. The survey also revealed two drivers for such strategies: prosocial and impression management motives. The former aimed to cultivate positive relationships, the latter to present a positive front.</p><p>The researchers found deep actors were driven by prosocial motives and enjoyed advantages from their strategy of choice. These actors reported lower levels of fatigue, fewer feelings of inauthenticity, improved coworker trust, and advanced progress toward career goals. </p><p>As Gabriel told <a href="https://www.psypost.org/2021/01/new-psychology-research-suggests-deep-acting-can-reduce-fatigue-and-improve-your-work-life-59081" target="_blank" rel="noopener noreferrer">PsyPost in an interview</a>: "So, it's a win-win-win in terms of feeling good, performing well, and having positive coworker interactions."</p><p>Non-actors did not report the emotional exhaustion of their low-actor peers, but they also didn't enjoy the social gains of the deep actors. Finally, the regulators showed that the flip-flopping between surface and deep acting drained emotional reserves and strained office relationships.</p><p>"I think the 'fake it until you make it' idea suggests a survival tactic at work," Gabriel noted. "Maybe plastering on a smile to simply get out of an interaction is easier in the short run, but long term, it will undermine efforts to improve your health and the relationships you have at work. </p><p>"It all boils down to, 'Let's be nice to each other.' Not only will people feel better, but people's performance and social relationships can also improve."</p>
You'll be glad ya' decided to smile<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="88a0a6a8d1c1abfcf7b1aca8e71247c6"><iframe type="lazy-iframe" data-runner-src="https://www.youtube.com/embed/QOSgpq9EGSw?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span><p>But as with any research that relies on self-reported data, there are confounders here to untangle. Even during anonymous studies, participants may select socially acceptable answers over honest ones. They may further interpret their goal progress and coworker interactions more favorably than is accurate. And certain work conditions may not produce the same effects, such as toxic work environments or those that require employees to project negative emotions.</p><p>There also remains the question of the causal mechanism. If surface acting—or switching between surface and deep acting—is more mentally taxing than genuinely feeling an emotion, then what physiological process causes this fatigue? <a href="https://www.frontiersin.org/articles/10.3389/fnhum.2019.00151/full" target="_blank">One study published in the <em>Frontiers in Human Neuroscience</em></a><em> </em>measured hemoglobin density in participants' brains using an fNIRS while they expressed emotions facially. The researchers found no significant difference in energy consumed in the prefrontal cortex by those asked to deep act or surface act (though, this study too is limited by a lack of real-life task).<br></p><p>With that said, Gabriel's studies reinforce much of the current research on emotional labor. <a href="https://journals.sagepub.com/doi/abs/10.1177/2041386611417746" target="_blank">A 2011 meta-analysis</a> found that "discordant emotional labor states" (read: surface acting) were associated with harmful effects on well-being and performance. The analysis found no such consequences for deep acting. <a href="https://doi.apa.org/doiLanding?doi=10.1037%2Fa0022876" target="_blank" rel="noopener noreferrer">Another meta-analysis</a> found an association between surface acting and impaired well-being, job attitudes, and performance outcomes. Conversely, deep acting was associated with improved emotional performance.</p><p>So, although there's still much to learn on the emotional labor front, it seems Van Dyke's advice to a Leigh was half correct. We should put on a happy face, but it will <a href="https://bigthink.com/design-for-good/everything-you-should-know-about-happiness-in-one-infographic" target="_self">only help if we can feel it</a>.</p>
Archaeologists discover a cave painting of a wild pig that is now the world's oldest dated work of representational art.