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What your morning coffee really does to your brain
Your morning coffee is good for you - if you drink it at the right time.

- Caffeine, the main stimulant found in coffee, works on a chemical level to give you energy by replacing the biochemical adenosine, which makes you tired.
- There are many health benefits to caffeine, such as a boost in metabolism and an increase in physical performance/muscle strength.
- To get the most positive impacts of your daily caffeine intake, drink coffee between 10 in the morning and 12 noon or between 2 in the afternoon and 5 in the evening.
According to the International Coffee Organization (ICO), the world pours about 1.4 billion cups of coffee per day. This might explain why you rely so heavily on your Keurig every morning or why you stop at Starbucks on the way to work even though you're already running late.
How does your morning coffee really impact your brain? Most importantly, are there certain times of the day where your latte-caffeine boost is better for your health?
Your brain on coffee
Caffeine, the main stimulant in coffee, works on a chemical level to give you a boost of energy. However, caffeine is structurally similar to another chemical naturally created in the body, called adenosine, which makes you tired.
Some substances imitate natural neurotransmitters and can take their place in receptors. For example, morphine can bind to the receptors in the brain meant for your endorphins (which is a natural kind of 'morphine' produced by your brain).
Caffeine replaces adenosine, which builds your adrenaline and causes dopamine to linger longer.
Similar to how morphine binds to endorphin receptors, the caffeine in your morning coffee binds to your brain's adenosine receptors, preventing the biochemical from making you tired.
Caffeine also builds your adrenaline supply which increases your heart rate and allows blood to pump faster. At the same time, caffeine prevents dopamine from being reabsorbed into your system, which allows it to linger in the brain for a longer amount of time, causing you to feel it's positive effects (such as happiness) for a longer amount of time.
This lingering of dopamine is what often triggers the brain to crave more caffeine. After all, while dopamine itself isn't inherently addictive, it does play a large role in many addictions.
More coffee means more adenosine receptors which means more coffee...
The brain is a complex and intricate system. The more coffee you drink, the more adenosine receptors are formed, meaning it can take more coffee to keep you awake now than it did when you started drinking coffee as a young adult.
According toresearch, caffeine has a half-life of around 6 hours.
Within the first 10 minutes, the caffeine enters your bloodstream and is pumped throughout your body, causing an increase in blood pressure and heart rate.
Up to 20 minutes after intake, caffeine binds to the adenosine receptors, neutralizing fatigue. Dopamine levels increase and linger, which provides the drinker with an alert and focused feeling.
Within 30 minutes, your adrenal glands shift into high gear and begin producing more hormones. During this time your vision may become sharper due to your pupils dilating.
Within 40 minutes, your body begins producing more serotonin, which improves the neuron function within your spinal cord - this leads to improved coordination and muscle strength.
After 4 hours, your metabolism increases, which is why you burn energy faster. Your body begins to break down stored fats during this time.
Within 6 hours, the liquid coffee has gone through your system and you will likely feel the urge to urinate, during which time approximately half the caffeine you consumed is expelled.
How to make your coffee habit benefit you
What time of day you drink your coffee can mean the difference between a good habit and a bad habit.
Photo by bluehand on Shutterstock
Of course, with anything caffeinated, moderation is key. When consumed in excess, caffeine can cause anxiety, heart palpitations, and sleeping problems.
According to Consumer Reports, up to 400mg of caffeine per day (which equals two to four 8 ounce cups) can be part of a healthy diet, however anything over 600mg per day is too much.
What are the health benefits of coffee?
Despite what you may have been told, there are several ways your daily caffeine intake is good for you. Not only can coffee improve your energy levels, but it can cause your brain to function at optimal levels, making you smarter.
Some other health benefits of coffee include:
- Boosting your metabolism
- Improving your physical performance
- Helping you with your nutrient intake (the vitamins B2, B3, B5, manganese, and potassium are all found in coffee)
- Lowering your risk of developing type 2 diabetes
- Helping fight depression symptoms and make you happier
- Providing a source of antioxidants
Consuming caffeine when cortisol levels are high decreases the health benefits.
Cortisol, a naturally-occurring stress hormone, has a very distinct circadian rhythm that is regulated by the brain's central pacemaker. Interrupting this rhythm can lead to metabolic abnormalities, fatigue, and poor quality of life, according to a 2009 study published in the Journal of Clinical Endocrinology and Metabolism.
Consuming caffeine when your cortisol levels are at a natural peak can lead to interference in the production of cortisol and an increase in your tolerance, which can impact your response to stress and will cause to you need more and more caffeine as time goes on.
When is the best time to drink coffee?
The cortisol levels in your body are at a natural peak three times per day, one of which is in the early morning. According to this article in Time Magazine, the best times to drink coffee (or ingest caffeine) are between 10 in the morning and 12 noon, and then again between 2 in the afternoon and 5 in the evening.
This will allow your brain to make the most of your caffeine surge, as it's not replacing any other important functions, such as the cortisol release that naturally happens several times per day.
- Study: hot coffee is better for you than cold brew - Big Think ›
- Daily Coffee Prevents Disease, Helps You Live Longer - Big Think ›
- Tea's health benefits can boost your mood and productivity - Big Think ›
- Study finds coffee during pregnancy may be a bad idea - Big Think ›
Iron Age discoveries uncovered outside London, including a ‘murder’ victim
A man's skeleton, found facedown with his hands bound, was unearthed near an ancient ceremonial circle during a high speed rail excavation project.
- A skeleton representing a man who was tossed face down into a ditch nearly 2,500 years ago with his hands bound in front of his hips was dug up during an excavation outside of London.
- The discovery was made during a high speed rail project that has been a bonanza for archaeology, as the area is home to more than 60 ancient sites along the planned route.
- An ornate grave of a high status individual from the Roman period and an ancient ceremonial circle were also discovered during the excavations.
Foul play?
<p>A skeleton representing a man who was tossed face down into a ditch nearly 2,500 years ago with his hands bound in front of his hips was dug up during a high speed rail excavation.</p><p>The positioning of the remains have led archaeologists to suspect that the man may have been a victim of an ancient murder or execution. Though any bindings have since decomposed, his hands were positioned together and pinned under his pelvis. There was also no sign of a grave or coffin. </p><p>"He seems to have had his hands tied, and he was face-down in the bottom of the ditch," <a href="https://www.livescience.com/iron-age-murder-victim-england.html" target="_blank">said archaeologist Rachel Wood</a>, who led the excavation. "There are not many ways that you end up that way."</p><p>Currently, archaeologists are examining the skeleton to uncover more information about the circumstances of the man's death. Fragments of pottery found in the ditch may offer some clues as to exactly when the man died. </p><p>"If he was struck across the head with a heavy object, you could find a mark of that on the back of the skull," Wood said to <a href="https://www.livescience.com/iron-age-murder-victim-england.html" target="_blank">Live Science</a>. "If he was stabbed, you could find blade marks on the ribs. So we're hoping to find something like that, to tell us how he died."</p>Other discoveries at Wellwick Farm
<p>The grim discovery was made at Wellwick Farm near Wendover. That is about 15 miles north-west of the outskirts of London, where <a href="https://www.hs2.org.uk/building-hs2/hs2-green-corridor/" target="_blank">a tunnel</a> is going to be built as part of a HS2 high-speed rail project due to open between London and several northern cities sometime after 2028. The infrastructure project has been something of a bonanza for archaeology as the area is home to more than 60 ancient sites along the planned route that are now being excavated before construction begins. </p><p>The farm sits less than a mile away from the ancient highway <a href="http://web.stanford.edu/group/texttechnologies/cgi-bin/stanfordnottingham/places/?icknield" target="_blank">Icknield Way</a> that runs along the tops of the Chiltern Hills. The route (now mostly trails) has been used since prehistoric times. Evidence at Wellwick Farm indicates that from the Neolithic to the Medieval eras, humans have occupied the region for more than 4,000 years, making it a rich area for archaeological finds. </p><p>Wood and her colleagues found some evidence of an ancient village occupied from the late Bronze Age (more than 3,000 years ago) until the Roman Empire's invasion of southern England about 2,000 years ago. At the site were the remains of animal pens, pits for disposing food, and a roundhouse — a standard British dwelling during the Bronze Age constructed with a circular plan made of stone or wood topped with a conical thatched roof.</p>Ceremonial burial site
<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yMzUzMTk0Ni9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTY0NDgwNTIyMX0.I49n1-j8WVhKjIZS_wVWZissnk3W1583yYXB7qaGtN8/img.jpg?width=1245&coordinates=0%2C82%2C0%2C83&height=700" id="44da7" class="rm-shortcode" data-rm-shortcode-id="46cfc8ca1c64fc404b32014542221275" data-rm-shortcode-name="rebelmouse-image" alt="top down view of coffin" data-width="1245" data-height="700" />A high status burial in a lead-lined coffin dating back to Roman times.
Photo Credit: HS2
<p>While these ancient people moved away from Wellwick Farm before the Romans invaded, a large portion of the area was still used for ritual burials for high-status members of society, Wood told Live Science. The ceremonial burial site included a circular ditch (about 60 feet across) at the center, and was a bit of a distance away from the ditch where the (suspected) murder victim was uncovered. Additionally, archaeologists found an ornately detailed grave near the sacred burial site that dates back to the Roman period, hundreds of years later when the original Bronze Age burial site would have been overgrown.</p><p>The newer grave from the Roman period encapsulated an adult skeleton contained in a lead-lined coffin. It's likely that the outer coffin had been made of wood that rotted away. Since it was clearly an ornate burial, the occupant of the grave was probably a person of high status who could afford such a lavish burial. However, according to Wood, no treasures or tokens had been discovered. </p>Sacred timber circle
<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yMzUzMTk0Ny9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTY2MDAwOTQ4Mn0.eVJAUcD0uBUkVMFuMOPSgH8EssGkfLf_MjwUv0zGCI8/img.jpg?width=1245&coordinates=0%2C149%2C0%2C149&height=700" id="9de6a" class="rm-shortcode" data-rm-shortcode-id="ee66520d470b26f5c055eaef0b95ec06" data-rm-shortcode-name="rebelmouse-image" alt="An aerial view of the sacred circular monument." data-width="1245" data-height="700" />An aerial view of the sacred circular monument.
Photo Credit: HS2
<p>One of the most compelling archaeological discoveries at Wellwick Farm are the indications of a huge ceremonial circle once circumscribed by timber posts lying south of the Bronze Age burial site. Though the wooden posts have rotted away, signs of the post holes remain. It's thought to date from the Neolithic period to 5,000 years ago, according to Wood.</p><p>This circle would have had a diameter stretching 210 feet across and consisted of two rings of hundreds of posts. There would have been an entry gap to the south-west. Five posts in the very center of the circle aligned with that same gap, which, according to Wood, appeared to have been in the direction of the rising sun on the day of the midwinter solstice. </p><p>Similar Neolithic timber circles have been discovered around Great Britain, such as one near <a href="https://bigthink.com/culture-religion/stonehenge-sarsens" target="_blank">Stonehenge</a> that is considered to date back to around the same time. </p>Skepticism: Why critical thinking makes you smarter
Being skeptical isn't just about being contrarian. It's about asking the right questions of ourselves and others to gain understanding.
- It's not always easy to tell the difference between objective truth and what we believe to be true. Separating facts from opinions, according to skeptic Michael Shermer, theoretical physicist Lawrence Krauss, and others, requires research, self-reflection, and time.
- Recognizing your own biases and those of others, avoiding echo chambers, actively seeking out opposing voices, and asking smart, testable questions are a few of the ways that skepticism can be a useful tool for learning and growth.
- As Derren Brown points out, being "skeptical of skepticism" can also lead to interesting revelations and teach us new things about ourselves and our psychology.
New study suggests placebo might be as powerful as psychedelics
New study suggests the placebo effect can be as powerful as microdosing LSD.
- New research from Imperial College London investigated the psychological effects of microdosing LSD in 191 volunteers.
- While microdosers experienced beneficial mental health effects, the placebo group performed statistically similar to those who took LSD.
- Researchers believe the expectation of a trip could produce some of the same sensations as actually ingesting psychedelics.
Psychedelics: The scientific renaissance of mind-altering drugs
<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="92360c805fe66c11de38a75b0967f417"><iframe type="lazy-iframe" data-runner-src="https://www.youtube.com/embed/5T0LmbWROKY?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span><p>For the study published in eLife, the team recruited 191 citizen cosmonauts to microdose either LSD or a placebo over the course of several weeks and note the psychological effects. Volunteers were already microdosing LSD, so there was no true control. Each volunteer was given instructions on creating their own low-dose gel capsules, some containing LSD, others not. Then they mixed the capsules in envelopes so they didn't know if they were taking the real thing or not.</p><p>The trial design was ingenious: each capsule featured a QR code that was scanned after the addition of ingredients but before they were placed in the envelope so that researchers knew what they were ingesting.</p><p>The problem: volunteers sourced their own LSD. Lack of quality control could have had a profound effect on the results. </p><p>The results: LSD microdosers reported feeling more mindful, satisfied with life, and better overall; they also noticed a reduction in feelings of paranoia. </p><p>The catch: the control group felt the same thing, with no statistical difference between the groups. </p><p>Lead author Balázs Szigeti comments on the findings: "This suggests that the improvements may not be due to the pharmacological action of the drug but can instead be explained by the placebo effect." </p>Credit: Alexander / Adobe Stock
<p>Psychedelics are notoriously difficult to control for given the intensity of the experience. Yet there is precedent for the above findings. A <a href="https://link.springer.com/article/10.1007/s00213-020-05464-5" target="_blank">2019 study</a> found that 61 percent of volunteers that took a placebo instead of psilocybin felt some psychedelic effects, with a few volunteers experiencing full-on trips.</p><p style="margin-left: 20px;">"Several stated that they saw the paintings on the walls 'move' or 'reshape' themselves, others felt 'heavy. . . as if gravity [had] a stronger hold', and one had a 'come down' before another 'wave' hit her."</p><p>The Imperial team believes the expectation of a trip might have been enough to produce similar results. Senior author David Erritzoe is excited for future studies on the topic, believing they tapped into a new wave of citizen science that could push forward our knowledge of psychedelic substances.</p><p style="margin-left: 20px;">"Accounting for the placebo effect is important when assessing trends such as the use of cannabidiol oils, fad diets or supplements where social pressure or users' expectations can lead to a strong placebo response. Self-blinding citizen science initiatives could be used as an inexpensive, initial screening tool before launching expensive clinical studies."</p><p>As investments into the psychedelics market explode, with one company <a href="https://www.bloomberg.com/news/articles/2021-03-03/thiel-backed-magic-mushroom-firm-atai-hits-2-billion-valuation" target="_blank">reaching a $2 billion valuation</a>, a recurring irony appears in the long arc of psychedelics and research: the power of our minds might be enough to feel greater life satisfaction and a deeper sense of mindfulness. If that's possible with a placebo, we have to question why the rush to create more pharmacology is necessary. </p><p>This is, mind you, a separate conversation over the role of psychedelics and rituals for group bonding. The function of group cohesion around consciousness-altering substances will continue to play an important role in many communities. </p><p>Of course, we should continue to explore the efficacy of psychedelics on anxiety, depression, suicidal ideation, PTSD, and addiction. <a href="https://bigthink.com/surprising-science/antidepressant-effects" target="_self">Pharmacological dependence</a> is a stain on the psychiatry industry. Whether or not psychedelics can be prescribed for daily use remains to be seen, but we know a moneyed interest is expecting a return on investment—the above company, ATAI Life Sciences, raised $157 million in its Series D round. </p><p>When it comes to wellbeing, some things money just can't buy. How we navigate the tricky terrain of mainstreaming psychedelics remains to be seen. </p><p>--</p><p><em>Stay in touch with Derek on <a href="http://www.twitter.com/derekberes" target="_blank">Twitter</a> and <a href="https://www.facebook.com/DerekBeresdotcom" target="_blank" rel="noopener noreferrer">Facebook</a>. His most recent book is</em> "<em><a href="https://www.amazon.com/gp/product/B08KRVMP2M?pf_rd_r=MDJW43337675SZ0X00FH&pf_rd_p=edaba0ee-c2fe-4124-9f5d-b31d6b1bfbee" target="_blank" rel="noopener noreferrer">Hero's Dose: The Case For Psychedelics in Ritual and Therapy</a>."</em></p>Your genetics influence how resilient you are to the cold
What makes some people more likely to shiver than others?
