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This Project Aims To Create Virtual Avatars Of Us All
It's for our health: The Virtual Physiological Human project seeks to create an accurate computer-simulated replica of a patient so that doctors can better predict how certain procedures and medications will work.
What's the Latest Development?
A large, multinational project involving over 100 researchers has as its ultimate goal the ability to create an accurate computer simulation of an individual patient's body on which doctors can test treatments and predict events such as childbirth. The University of Sheffield's year-old Insigneo Institute is spearheading the Virtual Physiological Human project, which has already received over £20 million (about US$33.7 million) in funding. A recent researchers' meeting revealed how each of them are progressing within their particular specialty. For example, British Heart Foundation fellow Dr. Paul Morris described his work with personalized virtual heart arteries.
What's the Big Idea?
The challenge of recreating an entire human body in silico is huge, and the goal won't be reached for some time to come, but rapid advances in technology could bring us predictive healthcare sooner than we think. Insigneo scientific director Marco Viceconti says, "Computers are nothing special – they know what we know, and sometimes not even that. But they can stitch things together and they’re not scared by sheer size. If we could know in advance which patient would respond to which treatment, we would just quantum leap our efficacy – without inventing anything. The opportunities are enormous."
Photo Credit: Shutterstock.com
What is human dignity? Here's a primer, told through 200 years of great essays, lectures, and novels.
- Human dignity means that each of our lives have an unimpeachable value simply because we are human, and therefore we are deserving of a baseline level of respect.
- That baseline requires more than the absence of violence, discrimination, and authoritarianism. It means giving individuals the freedom to pursue their own happiness and purpose.
- We look at incredible writings from the last 200 years that illustrate the push for human dignity in regards to slavery, equality, communism, free speech and education.
The inherent worth of all human beings<p>Human dignity is the inherent worth of each individual human being. Recognizing human dignity means respecting human beings' special value—value that sets us apart from other animals; value that is intrinsic and cannot be lost.</p> <p>Liberalism—the broad political philosophy that organizes society around liberty, justice, and equality—is rooted in the idea of human dignity. Liberalism assumes each of our lives, plans, and preferences have some unimpeachable value, not because of any objective evaluation or contribution to a greater good, but simply because they belong to a human being. We are human, and therefore deserving of a baseline level of respect. </p> <p>Because so many of us take human dignity for granted—just a fact of our humanness—it's usually only when someone's dignity is ignored or violated that we feel compelled to talk about it. </p> <p>But human dignity means more than the absence of violence, discrimination, and authoritarianism. It means giving individuals the freedom to pursue their own happiness and purpose—a freedom that can be hampered by restrictive social institutions or the tyranny of the majority. The liberal ideal of the good society is not just peaceful but also pluralistic: It is a society in which we respect others' right to think and live differently than we do.</p>
From the 19th century to today<p>With <a href="https://books.google.com/ngrams/graph?year_start=1800&year_end=2019&content=human+dignity&corpus=26&smoothing=3&direct_url=t1%3B%2Chuman%20dignity%3B%2Cc0" target="_blank" rel="noopener noreferrer">Google Books Ngram Viewer</a>, we can chart mentions of human dignity from 1800-2019.</p><img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNDg0ODU0My9vcmlnaW4ucG5nIiwiZXhwaXJlc19hdCI6MTY1MTUwMzE4MX0.bu0D_0uQuyNLyJjfRESNhu7twkJ5nxu8pQtfa1w3hZs/img.png?width=980" id="7ef38" class="rm-shortcode" data-rm-shortcode-id="9974c7bef3812fcb36858f325889e3c6" data-rm-shortcode-name="rebelmouse-image" />
American novelist, writer, playwright, poet, essayist and civil rights activist James Baldwin at his home in Saint-Paul-de-Vence, southern France, on November 6, 1979.
Credit: Ralph Gatti/AFP via Getty Images
The future of dignity<p>Around the world, people are still working toward the full and equal recognition of human dignity. Every year, new speeches and writings help us understand what dignity is—not only what it looks like when dignity is violated but also what it looks like when dignity is honored. In his posthumous essay, Congressman Lewis wrote, "When historians pick up their pens to write the story of the 21st century, let them say that it was your generation who laid down the heavy burdens of hate at last and that peace finally triumphed over violence, aggression and war."</p> <p>The more we talk about human dignity, the better we understand it. And the sooner we can make progress toward a shared vision of peace, freedom, and mutual respect for all. </p>
Scientists find that bursts of gamma rays may exceed the speed of light and cause time-reversibility.
- Astrophysicists propose that gamma-ray bursts may exceed the speed of light.
- The superluminal jets may also be responsible for time-reversibility.
- The finding doesn't go against Einstein's theory because this effect happens in the jet medium not a vacuum.
Jet bursting out of a blazar. Black-hole-powered galaxies called blazars are the most common sources detected by NASA's Fermi Gamma-ray Space Telescope.
Cosmic death beams: Understanding gamma ray bursts<div class="rm-shortcode" data-media_id="cu2knVEk" data-player_id="FvQKszTI" data-rm-shortcode-id="c6cfd20fdf31c82cb206ade8ce21ba3f"> <div id="botr_cu2knVEk_FvQKszTI_div" class="jwplayer-media" data-jwplayer-video-src="https://content.jwplatform.com/players/cu2knVEk-FvQKszTI.js"> <img src="https://cdn.jwplayer.com/thumbs/cu2knVEk-1920.jpg" class="jwplayer-media-preview" /> </div> <script src="https://content.jwplatform.com/players/cu2knVEk-FvQKszTI.js"></script> </div>
Britons could start receiving the vaccine within days.
- The U.K. issued emergency authorization Wednesday for the Pfizer/BioNTech COVID-19 vaccine, becoming the first nation in the West to approve a rigorously tested vaccine.
- The U.S. will meet on December 10 to decide whether to approve Pfizer's vaccine, which achieved an efficacy rate of 90 percent in clinical trials.
- Moderna has also produced a vaccine that could be approved in the U.S. later in December.
Credit: Lubo Ivanko via Adobe Stock<p style="margin-left: 20px;">"The government has today accepted the recommendation from the independent <a href="https://www.gov.uk/government/organisations/medicines-and-healthcare-products-regulatory-agency" target="_blank" rel="noopener noreferrer">Medicines and Healthcare products Regulatory Agency (MHRA)</a> to approve Pfizer/BioNTech's COVID-19 vaccine for use," said a spokesperson for the Department of Health and Social Care. "This follows months of rigorous clinical trials and a thorough analysis of the data by experts at the MHRA who have concluded that the vaccine has met its strict standards of safety, quality and effectiveness."</p><p>Why did the U.K. beat the U.S. and other Western nations to approving the vaccine? The reason lies in the rigorousness of testing on which nations are basing their decisions: The U.K. chose to rely on findings reported by Pfizer itself. Meanwhile, the U.S. is having regulators independently examine raw data behind tests on Pfizer's vaccine.</p><p>F.D.A Commissioner Steve Hahn defended the administration's slower pace on Wednesday during a Facebook live stream.</p><p style="margin-left: 20px;">"We have to go through it very carefully," he said, declining to announce a concrete timeline for the potential distribution of the Pfizer vaccine. "All I can tell you is not knowing the data, [it will be] very soon after those meetings. I don't want to get ahead of the data … it wouldn't be the first time that the FDA and Advisory committee has found surprises."</p>
Credit: Pixabay<p>On December 10, the F.D.A. will decide whether to issue emergency approval of the vaccine. If authorized, health systems in the U.S. could receive the first rounds of vaccines on Dec. 15, according to an Operation Warp Speed document obtained by CNN. The document estimated that 22.5 million doses of Pfizer's vaccine will be produced in December.</p><p>Moderna has also produced a COVID-19 vaccine with a high efficacy rate. The F.D.A. will meet Dec. 17 to discuss approving that vaccine, which, like Pfizer's, uses messenger RNA to trigger an immune response. Moderna says its <a href="https://www.sciencemag.org/news/2020/11/absolutely-remarkable-no-one-who-got-modernas-vaccine-trial-developed-severe-covid-19" target="_blank">vaccine has an efficacy rate of about 94 percent</a>; Pfizer reported a rate of 90 percent. Similar to the U.K., the first Americans to receive COVID-19 vaccines will be the elderly, healthcare workers, and people at risk due to preexisting conditions.</p>
Philosophers have been asking the question for hundreds of years. Now neuroscientists are joining the quest to find out.
- The debate over whether or not humans have free will is centuries old and ongoing. While studies have confirmed that our brains perform many tasks without conscious effort, there remains the question of how much we control and when it matters.
- According to Dr. Uri Maoz, it comes down to what your definition of free will is and to learning more about how we make decisions versus when it is ok for our brain to subconsciously control our actions and movements.
- "If we understand the interplay between conscious and unconscious," says Maoz, "it might help us realize what we can control and what we can't."
Puerto Rico's iconic telescope facilitated important scientific discoveries while inspiring young scientists and the public imagination.