The Multiverse Has 11 Dimensions
Michio Kaku
Dr. Michio Kaku is the co-founder of string field theory, and is one of the most widely recognized scientists in the world today. He has written 4 New York Times Best Sellers, is the science correspondent for CBS This Morning and has hosted numerous science specials for BBC-TV, the Discovery/Science Channel. His radio show broadcasts to 100 radio stations every week. Dr. Kaku holds the Henry Semat Chair and Professorship in theoretical physics at the City College of New York (CUNY), where he has taught for over 25 years. He has also been a visiting professor at the Institute for Advanced Study as well as New York University (NYU).
Question: Are there only three dimensions in other universes or could there be more? (Submitted by Andre Lapiere)
Michio Kaku: Andre, we believe, though we cannot yet prove, that our multiverse of universes is 11-dimensional. So think of this 11-dimensional arena and in this arena there are bubbles, bubbles that float and the skin of the bubble represents an entire universe, so we’re like flies trapped on fly paper. We’re on the skin of a bubble. It’s a three dimensional bubble. The three dimensional bubble is expanding and that is called the Big Bang theory and sometimes these bubbles can bump into each other, sometimes they can split apart and that we think is the Big Bang. So we even have a theory of the Big Bang itself. Now you ask a question what about the dimensions of each bubble. Well in string theory—which is what I do for a living; that's my day job—in string theory we can have bubbles of different dimensions. The highest dimension is 11. You cannot go beyond 11 because universes become unstable beyond 11. If I write down the theory of a 13-, 15-dimensional universe it’s unstable and it collapses down to an 11-dimensional universe. But within 11 dimensions you can have bubbles that are 3 dimensional, 4-dimensional, 5-dimensional. These are membranes, so for short we call them branes. So these branes can exist in different dimensions and let’s say P represents the dimension of each bubble, so we call them p-branes. So a p-brane is a universe in different dimensions floating in a much larger arena, and this larger arena is the hyperspace that I talked about originally.
Also remember that each bubble vibrates, and each bubble vibrating creates music. The music of these membranes is the subatomic particles. Each subatomic particle represents a note on a vibrating string or vibrating membranes. So, believe it or not, we now have a candidate for the "Mind of God" that Albert Einstein wrote about for the last 30 years of his life. The "Mind of God" in this picture would be cosmic music resonating throughout 11-dimensional hyperspace.
Recorded September 29, 2010
Interviewed by Paul Hoffman
The physicist explains why other universes in the mulitverse could have many more dimensions—and could comprise Einstein's "Mind of God."
Big ideas.
Once a week.
Subscribe to our weekly newsletter.
How tiny bioelectronic implants may someday replace pharmaceutical drugs
Scientists are using bioelectronic medicine to treat inflammatory diseases, an approach that capitalizes on the ancient "hardwiring" of the nervous system.
24 February, 2021
Credit: Adobe Stock / SetPoint Medical
Sponsored by Northwell Health
- Bioelectronic medicine is an emerging field that focuses on manipulating the nervous system to treat diseases.
- Clinical studies show that using electronic devices to stimulate the vagus nerve is effective at treating inflammatory diseases like rheumatoid arthritis.
- Although it's not yet approved by the US Food and Drug Administration, vagus nerve stimulation may also prove effective at treating other diseases like cancer, diabetes and depression.
<p>Could a tiny electronic device treat some diseases more safely and effectively than pharmaceutical medicines?</p><p>For Kelly Owens, the answer was clear. She spent more than a decade suffering from Crohn's disease, a chronic inflammatory bowel disease that left her with severe arthritis in her joints. The pain forced her to use a cane, sometimes a wheelchair. She tried more than 20 medications and racked up more than $1 million in medical bills, but her condition didn't improve.</p><p>A physician told Owens and her husband that they shouldn't have children, and that she'd have to take steroids for life.</p><p>Then Owens turned to bioelectronic medicine. She reached out to Dr. Kevin Tracey, a pioneer in the field and president and CEO of the Feinstein Institutes for Medical Research in New York. Soon after, Owens and her husband moved to Amsterdam to participate in a clinical trial involving a relatively new bioelectronic approach to treat inflammation.</p><p>Doctors implanted a small electronic device in her chest that stimulated her vagus nerve, the body's longest cranial nerve. After two weeks, Owens didn't need the cane or wheelchair. Soon she was jogging on a treadmill.</p><p>A growing body of research within bioelectronic medicine shows it's possible to treat diseases by manipulating the nervous system. The field is essentially a fusion of neuroscience, molecular biology and neurotechnology. Dr. Tracey and his colleagues think the field may someday replace or supplement many pharmaceutical drugs used to treat major diseases, including cancer and Alzheimer's.</p><p>But how? The answer centers on how the nervous system controls molecular processes in the body.</p>
<blockquote>...the most revolutionary aspect of bioelectronic medicine, according to Dr. Tracey, is that approaches like vagus nerve stimulation wouldn't come with harmful and potentially deadly side effects, as many pharmaceutical drugs currently do.</blockquote>
The nervous system’s ancient reflexes
<p>You accidentally place your hand on a hot stove. Almost instantaneously, your hand withdraws.</p><p>What triggered your hand to move? The answer is <em>not</em> that you consciously decided the stove was hot and you should move your hand. Rather, it was a reflex: Skin receptors on your hand sent nerve impulses to the spinal cord, which ultimately sent back motor neurons that caused your hand to move away. This all occurred before your "conscious brain" realized what happened.</p><p>Similarly, the nervous system has reflexes that protect individual cells in the body.</p><p>"The nervous system evolved because we need to respond to stimuli in the environment," said Dr. Tracey. "Neural signals don't come from the brain down first. Instead, when something happens in the environment, our peripheral nervous system senses it and sends a signal to the central nervous system, which comprises the brain and spinal cord. And then the nervous system responds to correct the problem."</p><p>So, what if scientists could "hack" into the nervous system, manipulating the electrical activity in the nervous system to control molecular processes and produce desirable outcomes? That's the chief goal of bioelectronic medicine.</p><p>"There are billions of neurons in the body that interact with almost every cell in the body, and at each of those nerve endings, molecular signals control molecular mechanisms that can be defined and mapped, and potentially put under control," Dr. Tracey said in a <a href="https://www.youtube.com/watch?v=AJH9KsMKi5M" target="_blank">TED Talk</a>.</p><p>"Many of these mechanisms are also involved in important diseases, like cancer, Alzheimer's, diabetes, hypertension and shock. It's very plausible that finding neural signals to control those mechanisms will hold promises for devices replacing some of today's medication for those diseases."</p><p>How can scientists hack the nervous system? For years, researchers in the field of bioelectronic medicine have zeroed in on the longest cranial nerve in the body: the vagus nerve.</p><blockquote>What's more, clinical trials show that vagus nerve stimulation not only "shuts off" inflammation, but also triggers the production of cells that promote healing.</blockquote>
The vagus nerve
<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNTYyOTM5OC9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTY0NTIwNzk0NX0.UCy-3UNpomb3DQZMhyOw_SQG4ThwACXW_rMnc9mLAe8/img.jpg?width=1245&coordinates=0%2C0%2C0%2C0&height=700" id="09add" class="rm-shortcode" data-rm-shortcode-id="f38dbfbbfe470ad85a3b023dd5083557" data-rm-shortcode-name="rebelmouse-image" data-width="1245" data-height="700" />Electrical signals, seen here in a synapse, travel along the vagus nerve to trigger an inflammatory response.
Credit: Adobe Stock via solvod
<p>The vagus nerve ("vagus" meaning "wandering" in Latin) comprises two nerve branches that stretch from the brainstem down to the chest and abdomen, where nerve fibers connect to organs. Electrical signals constantly travel up and down the vagus nerve, facilitating communication between the brain and other parts of the body.</p><p>One aspect of this back-and-forth communication is inflammation. When the immune system detects injury or attack, it automatically triggers an inflammatory response, which helps heal injuries and fend off invaders. But when not deployed properly, inflammation can become excessive, exacerbating the original problem and potentially contributing to diseases.</p><p>In 2002, Dr. Tracey and his colleagues discovered that the nervous system plays a key role in monitoring and modifying inflammation. This occurs through a process called the <a href="https://www.nature.com/articles/nature01321" target="_blank" rel="noopener noreferrer">inflammatory reflex</a>. In simple terms, it works like this: When the nervous system detects inflammatory stimuli, it reflexively (and subconsciously) deploys electrical signals through the vagus nerve that trigger anti-inflammatory molecular processes.</p><p>In rodent experiments, Dr. Tracey and his colleagues observed that electrical signals traveling through the vagus nerve control TNF, a protein that, in excess, causes inflammation. These electrical signals travel through the vagus nerve to the spleen. There, electrical signals are converted to chemical signals, triggering a molecular process that ultimately makes TNF, which exacerbates conditions like rheumatoid arthritis.</p><p>The incredible chain reaction of the inflammatory reflex was observed by Dr. Tracey and his colleagues in greater detail through rodent experiments. When inflammatory stimuli are detected, the nervous system sends electrical signals that travel through the vagus nerve to the spleen. There, the electrical signals are converted to chemical signals, which trigger the spleen to create a white blood cell called a T cell, which then creates a neurotransmitter called acetylcholine. The acetylcholine interacts with macrophages, which are a specific type of white blood cell that creates TNF, a protein that, in excess, causes inflammation. At that point, the acetylcholine triggers the macrophages to stop overproducing TNF – or inflammation.</p><p>Experiments showed that when a specific part of the body is inflamed, specific fibers within the vagus nerve start firing. Dr. Tracey and his colleagues were able to map these relationships. More importantly, they were able to stimulate specific parts of the vagus nerve to "shut off" inflammation.</p><p>What's more, clinical trials show that vagus nerve stimulation not only "shuts off" inflammation, but also triggers the production of cells that promote healing.</p><p>"In animal experiments, we understand how this works," Dr. Tracey said. "And now we have clinical trials showing that the human response is what's predicted by the lab experiments. Many scientific thresholds have been crossed in the clinic and the lab. We're literally at the point of regulatory steps and stages, and then marketing and distribution before this idea takes off."<br></p>The future of bioelectronic medicine
<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNTYxMDYxMy9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYzNjQwOTExNH0.uBY1TnEs_kv9Dal7zmA_i9L7T0wnIuf9gGtdRXcNNxo/img.jpg?width=980" id="8b5b2" class="rm-shortcode" data-rm-shortcode-id="c005e615e5f23c2817483862354d2cc4" data-rm-shortcode-name="rebelmouse-image" data-width="2000" data-height="1125" />Vagus nerve stimulation can already treat Crohn's disease and other inflammatory diseases. In the future, it may also be used to treat cancer, diabetes, and depression.
Credit: Adobe Stock via Maridav
<p>Vagus nerve stimulation is currently awaiting approval by the US Food and Drug Administration, but so far, it's proven safe and effective in clinical trials on humans. Dr. Tracey said vagus nerve stimulation could become a common treatment for a wide range of diseases, including cancer, Alzheimer's, diabetes, hypertension, shock, depression and diabetes.</p><p>"To the extent that inflammation is the problem in the disease, then stopping inflammation or suppressing the inflammation with vagus nerve stimulation or bioelectronic approaches will be beneficial and therapeutic," he said.</p><p>Receiving vagus nerve stimulation would require having an electronic device, about the size of lima bean, surgically implanted in your neck during a 30-minute procedure. A couple of weeks later, you'd visit, say, your rheumatologist, who would activate the device and determine the right dosage. The stimulation would take a few minutes each day, and it'd likely be unnoticeable.</p><p>But the most revolutionary aspect of bioelectronic medicine, according to Dr. Tracey, is that approaches like vagus nerve stimulation wouldn't come with harmful and potentially deadly side effects, as many pharmaceutical drugs currently do.</p><p>"A device on a nerve is not going to have systemic side effects on the body like taking a steroid does," Dr. Tracey said. "It's a powerful concept that, frankly, scientists are quite accepting of—it's actually quite amazing. But the idea of adopting this into practice is going to take another 10 or 20 years, because it's hard for physicians, who've spent their lives writing prescriptions for pills or injections, that a computer chip can replace the drug."</p><p>But patients could also play a role in advancing bioelectronic medicine.</p><p>"There's a huge demand in this patient cohort for something better than they're taking now," Dr. Tracey said. "Patients don't want to take a drug with a black-box warning, costs $100,000 a year and works half the time."</p><p>Michael Dowling, president and CEO of Northwell Health, elaborated:</p><p>"Why would patients pursue a drug regimen when they could opt for a few electronic pulses? Is it possible that treatments like this, pulses through electronic devices, could replace some drugs in the coming years as preferred treatments? Tracey believes it is, and that is perhaps why the pharmaceutical industry closely follows his work."</p><p>Over the long term, bioelectronic approaches are unlikely to completely replace pharmaceutical drugs, but they could replace many, or at least be used as supplemental treatments.</p><p>Dr. Tracey is optimistic about the future of the field.</p><p>"It's going to spawn a huge new industry that will rival the pharmaceutical industry in the next 50 years," he said. "This is no longer just a startup industry. [...] It's going to be very interesting to see the explosive growth that's going to occur."</p>
Keep reading
Show less
Toward a disease-sniffing device that rivals a dog’s nose
Trained dogs can detect cancer and other diseases by smell. Could a device do the same?
25 February, 2021
JOEL SAGET/AFP via Getty Images
Technology & Innovation
Numerous studies have shown that trained dogs can detect many kinds of disease — including lung, breast, ovarian, bladder, and prostate cancers, and possibly Covid-19 — simply through smell. In some cases, involving prostate cancer for example, the dogs had a 99 percent success rate in detecting the disease by sniffing patients' urine samples.
<p>But it takes time to train such dogs, and their availability and time is limited. Scientists have been hunting for ways of automating the amazing olfactory capabilities of the canine nose and brain, in a compact device. Now, a team of researchers at MIT and other institutions has come up with a system that can detect the chemical and microbial content of an air sample with even greater sensitivity than a dog's nose. They coupled this to a machine-learning process that can identify the distinctive characteristics of the disease-bearing samples.</p><p>The findings, which the researchers say could someday lead to an automated odor-detection system small enough to be incorporated into a cellphone, are being published today in the journal PLOS One, in a paper by Claire Guest of Medical Detection Dogs in the U.K., Research Scientist Andreas Mershin of MIT, and 18 others at Johns Hopkins University, the Prostate Cancer Foundation, and several other universities and organizations.</p><p> “Dogs, for now 15 years or so, have been shown to be the earliest, most accurate disease detectors for anything that we've ever tried," Mershin says. And their performance in controlled tests has in some cases exceeded that of the best current lab tests, he says. “So far, many different types of cancer have been detected earlier by dogs than any other technology."</p><p>What's more, the dogs apparently pick up connections that have so far eluded human researchers: When trained to respond to samples from patients with one type of cancer, some dogs have then identified several other types of cancer — even though the similarities between the samples weren't evident to humans.</p>
<p>These dogs can identify "cancers that don't have any identical biomolecular signatures in common, nothing in the odorants," Mershin says. Using powerful analytical tools including gas chromatography mass spectrometry (GCMS) and microbial profiling, "if you analyze the samples from, let's say, skin cancer and bladder cancer and breast cancer and lung cancer — all things that the dog has been shown to be able to detect — they have nothing in common." Yet the dog can somehow generalize from one kind of cancer to be able to identify the others.</p><p>Mershin and the team over the last few years have developed, and continued to improve on, a miniaturized detector system that incorporates mammalian olfactory receptors stabilized to act as sensors, whose data streams can be handled in real-time by a typical smartphone's capabilities. He envisions a day when every phone will have a scent detector built in, just as cameras are now ubiquitous in phones. Such detectors, equipped with advanced algorithms developed through machine learning, could potentially pick up early signs of disease far sooner than typical screening regimes, he says — and could even warn of smoke or a gas leak as well.</p><p>In the latest tests, the team tested 50 samples of urine from confirmed cases of prostate cancer and controls known to be free of the disease, using both dogs trained and handled by Medical Detection Dogs in the U.K. and the miniaturized detection system. They then applied a machine-learning program to tease out any similarities and differences between the samples that could help the sensor-based system to identify the disease. In testing the same samples, the artificial system was able to match the success rates of the dogs, with both methods scoring more than 70 percent.</p><p>The miniaturized detection system, Mershin says, is actually 200 times more sensitive than a dog's nose in terms of being able to detect and identify tiny traces of different molecules, as confirmed through controlled tests mandated by DARPA. But in terms of interpreting those molecules, "it's 100 percent dumber." That's where the machine learning comes in, to try to find the elusive patterns that dogs can infer from the scent, but humans haven't been able to grasp from a chemical analysis.</p>
<p>"The dogs don't know any chemistry," Mershin says. "They don't see a list of molecules appear in their head. When you smell a cup of coffee, you don't see a list of names and concentrations, you feel an integrated sensation. That sensation of scent character is what the dogs can mine."</p><p>While the physical apparatus for detecting and analyzing the molecules in air has been under development for several years, with much of the focus on reducing its size, until now the analysis was lacking. "We knew that the sensors are already better than what the dogs can do in terms of the limit of detection, but what we haven't shown before is that we can train an artificial intelligence to mimic the dogs," he says. "And now we've shown that we can do this. We've shown that what the dog does can be replicated to a certain extent."</p><p>This achievement, the researchers say, provides a solid framework for further research to develop the technology to a level suitable for clinical use. Mershin hopes to be able to test a far larger set of samples, perhaps 5,000, to pinpoint in greater detail the significant indicators of disease. But such testing doesn't come cheap: It costs about $1,000 per sample for clinically tested and certified samples of disease-carrying and disease-free urine to be collected, documented, shipped, and analyzed he says.</p><p>Reflecting on how he became involved in this research, Mershin recalled a study of bladder cancer detection, in which a dog kept misidentifying one member of the control group as being positive for the disease, even though he had been specifically selected based on hospital tests as being disease free. The patient, who knew about the dog's test, opted to have further tests, and a few months later was found to have the disease at a very early stage. "Even though it's just one case, I have to admit that did sway me," Mershin says.</p><p>The team included researchers at MIT, Johns Hopkins University in Maryland, Medical Detection Dogs in Milton Keynes, U.K., the Cambridge Polymer Group, the Prostate Cancer Foundation, the University of Texas at El Paso, Imagination Engines, and Harvard University. The research was supported by the Prostate Cancer Foundation, the National Cancer Institute, and the National Institutes of Health.</p><p>Reprinted with permission of <a target="_blank" href="http://news.mit.edu/">MIT News</a>. Read the <a target="_blank" href="https://news.mit.edu/2021/disease-detection-device-dogs-0217" rel="noopener noreferrer">original article</a>.</p>
Keep reading
Show less
New research shows that bullies are often friends
Remedies must honor the complex social dynamics of adolescence.
25 February, 2021
Photo: rawpixel / Adobe Stock
Surprising Science
- Bullies are likely to be friends according to new research published in the American Journal of Sociology.
- The researchers write that complex social dynamics among adolescents allow the conditions for intragroup dominance.
- The team uses the concept of "frenemies" to describe the relationship between many bullies and victims.
<p>Where do your enemies come from? That's the topic of a <a href="https://www.journals.uchicago.edu/doi/10.1086/712972" target="_blank" rel="noopener noreferrer">new article</a> published in the American Journal of Sociology, which investigates school bullying, a social phenomenon that affects millions of children every year. Despite the belief that bullies are existential foes, it turns out that the bully and bullied are likely to be friends—at least, "frenemies."</p><p>Looking at 14 middle and high schools at two points in the year, the research team of Robert Faris, Diane Felmlee, and Cassie McMillan concluded that social proximity is not enough of a reason to abandon status elevation. Kids often climb over those closest to them in order to acquire greater standing in their networks—a power play that has adverse mental health effects on the bullied. </p><p>Their analysis began by comparing two parallel cohorts that create linear dominance hierarchies: chickens and summer campers. This game of dominance and ritualized submission is apparent in the barnyard and by the forest lake, as well as in high school, places where "overt aggression is not the only means by which status is attained." Prom queens, they note, "do not fight their way to their thrones." Subtler forms of bullying are often recruited. </p><p>Common wisdom has it that balance theory—the idea that enemies and friends share distinct social spaces—defines much of adolescent posturing. Not so, says this team: positive and negative ties are not as far apart as you might imagine. That's where the concept of "frenemies" comes in. Cruelty is a strange bonding tool that serves the purpose of status elevation, at least for the bully. </p><p style="margin-left: 20px;">"In contrast to both balance theory and much of the empirical literature on bullying, which concludes that victims are isolated or marginal and thus sit at relatively large social distances from their tormentors, we extend the logic of instrumental aggression to anticipate higher rates of aggression at low social distances, between friends and among structurally equivalent schoolmates."</p>
School Bullying: Are We Taking the Wrong Approach?
<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="dfd7e31a97e8a049081d3cf6b978714f"><iframe type="lazy-iframe" data-runner-src="https://www.youtube.com/embed/E3U38uZBW6w?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span><p>Femlee, a sociology professor at Penn State, says her study offers important insights into why bullying occurs—and, potentially, leaves clues for how to combat it. Her team found peer aggression to be much higher among students that are proximal to one another, either through friendship or social circles. Bullying does not end friendships, she says; they persist over the long-term, with the bullied maintaining ties to their tormentors. </p><p>Looking at a data set of over 3,000 students—at least half were either bullier or victim—the researchers asked students to choose five classmates that had been mean to them, then analyzed these networks while racking levels of anxiety, depression, and suicidal ideation. As one student remarked, "Sometimes your own friends bully you. I don't understand why, why my friends do this to me."</p><p>Femlee <a href="https://news.psu.edu/story/648500/2021/02/22/research/et-tu-brute-teens-may-be-more-likely-be-bullied-social-climbing" target="_blank" rel="noopener noreferrer">elaborates on the complex dynamics</a> of adolescence:</p><p style="margin-left: 20px;">"These conflicts likely arise between young people who are eyeing the same spot on the team, club, or vying for the same best friend or romantic partner. Those who are closely linked in the school social network are apt to encounter situations in which they are rivals for identical positions and social ties."</p><img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNTY4NzI0NS9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYzMzEzNzk3NH0.rj3oz_O5iObmxGMvYrqLXUlTXC9ReBqcMToEX75pBhM/img.jpg?width=1245&coordinates=0%2C0%2C0%2C0&height=700" id="4813c" class="rm-shortcode" data-rm-shortcode-id="658087c5920ae5126bfee8445e6977c6" data-rm-shortcode-name="rebelmouse-image" data-width="1245" data-height="700" />
Photo: motortion / Adobe Stock
<p>They note that strained friendships are more likely to produce dominance behavior and power differentials than close ties. Punching down is common, especially between students of the same gender, race, and grade. The race for recognition seems to necessitate close racial and gender ties. "Frenemies" usually result from one member of a group victimizing another in an attempt at clawing their way to the top of the network.</p><p>This competition can have lifelong effects, such as reducing the bullied's chances of developing intimate relationships. The authors note that most bullying prevention programs fail becuase, in part, "aggressive behavior accrues social rewards and does so to a degree that leads some to betray their closest friends."</p><p>Such programs tend to focus on a fraction of bullying dynamics, such as empathy deficits and emotional dysregulation. They fail to take into account the complex social dynamics of being a teenager. The authors believe coopting status contents and changing the behavior of high-status youths could have downline effects. Instead of dismantling hierarchies, they recommend recognizing status is intrinsic to group fitness instead of pretending the struggle to the top is an aberration. Only then can you create structural change. </p><p>Friends, they conclude, can be the problem but also offer the solution. Aiming for enduring friendships instead of backstabbing frenemies is a tall order but it could impact the tragedy of bullying—and the emotional carnage it leaves in its wake. </p><p>--</p><p><em>Stay in touch with Derek on <a href="http://www.twitter.com/derekberes" target="_blank">Twitter</a> and <a href="https://www.facebook.com/DerekBeresdotcom" target="_blank" rel="noopener noreferrer">Facebook</a>. His most recent book is</em> "<em><a href="https://www.amazon.com/gp/product/B08KRVMP2M?pf_rd_r=MDJW43337675SZ0X00FH&pf_rd_p=edaba0ee-c2fe-4124-9f5d-b31d6b1bfbee" target="_blank" rel="noopener noreferrer">Hero's Dose: The Case For Psychedelics in Ritual and Therapy</a>."</em></p>
Keep reading
Show less
Archaeologists identify contents of ancient Mayan drug containers
Scientists use new methods to discover what's inside drug containers used by ancient Mayan people.
18 January, 2021
Credit: WSU
Surprising Science
- Archaeologists used new methods to identify contents of Mayan drug containers.
- They were able to discover a non-tobacco plant that was mixed in by the smoking Mayans.
- The approach promises to open up new frontiers in the knowledge of substances ancient people consumed.
<p>Ancient Mayans have been a continuing source of inspiration for their monuments, knowledge, and mysterious demise. Now a new study discovers some of the drugs they used. <a href="https://www.nature.com/articles/s41598-021-81158-y" target="_blank">For the first time</a>, scientists found remnants of a non-tobacco plant in Mayan drug containers. They believe their analysis methods can allow them exciting new ways of investigating the different types of psychoactive and non-psychoactive plants used by the Maya and other pre-Colombian societies.</p><p>The research was carried out by a team from Washington State University, led by anthropology postdoc <a href="https://wsu.academia.edu/MarioZimmermann" target="_blank">Mario Zimmermann</a>. They spotted residue of the Mexican marigold (Tagetes lucida) in 14 tiny ceramic vessels that were buried over a 1,000 years ago on Mexico's Yucatan peninsula. The containers also exhibited chemical traces of two types of tobacco: Nicotiana tabacum and N. rustica. Scientists think the marigold was mixed in with the tobacco to make the experience more pleasant.</p>
<blockquote>"While it has been established that tobacco was commonly used throughout the Americas before and after contact, evidence of other plants used for medicinal or religious purposes has remained largely unexplored," said Zimmermann. "The analysis methods developed in collaboration between the Department of Anthropology and the Institute of Biological Chemistry give us the ability to investigate drug use in the ancient world like never before."</blockquote><p>The scientists used a new method based on <a href="https://www.future-science.com/doi/full/10.2144/000113133" target="_blank">metabolomics</a> that is able to pinpoint thousands of plant compounds, or metabolites, in residue of archaeological artifacts like containers and pipes. This allows the researchers to figure out which specific plants were utilized. The way plant residue was identified before employed looking for specific biomarkers from nicotine, caffeine, and other such substances. That approach would not be able to spot what else was consumed outside of what biomarker was found. The new way gives much more information, showing the researchers a fuller picture of what the ancient people ingested. </p>
<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNTQ5ODA2OS9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYyMTU5NjU3MH0.yulUX2V5W_S-eR5JE89cKODfRv3numTn_cjeBqbcYAk/img.jpg?width=980" id="023b8" class="rm-shortcode" data-rm-shortcode-id="0a4f30654bf0f0c2b8463aaaae455714" data-rm-shortcode-name="rebelmouse-image" data-width="640" data-height="480" />
PARME staff archaeologists excavating a burial site at the Tamanache site, Mérida, Yucatan.
Credit: WSU
<p>The containers in the study were found by Zimmerman and a team of archaeologists in 2012.</p><p style="margin-left: 20px;">"When you find something really interesting like an intact container it gives you a sense of joy," <a href="https://phys.org/news/2021-01-scientists-contents-ancient-maya-drug.html" target="_blank">shared</a> Zimmermann. "Normally, you are lucky if you find a jade bead. There are literally tons of pottery sherds but complete vessels are scarce and offer a lot of interesting research potential."</p><p>The researchers are negotiating with various Mexican institutions to be able to study more ancient containers for plant residues. They also aim to look at organic materials possibly preserved in the dental plaque of ancient remains. </p><p>Check out the study published in <a href="https://www.nature.com/articles/s41598-021-81158-y" target="_blank">Scientific Reports. </a></p>
Keep reading
Show less
Why cities are critical to achieving a carbon-neutral world
In May 2018, the city of Paris set an ambition to be carbon-neutral by 2050.
25 February, 2021
Photo by Rodrigo Kugnharski on Unsplash
Technology & Innovation
- Countries, governments and companies are aligning on a need for net-zero - and this is an opportunity to rethink decarbonizing our cities.
- There is no "one-size-fits-all" solution – each city's needs must be at the heart of developing integrated energy solutions.
- A city can only decarbonize through collaboration between government, the private sector, and local communities.
<p>The world is at a critical juncture. Never has there been a moment where businesses, energy consumers and governments – from Canada to China – are aligning on a common vision like this: a road to net-zero emissions.</p><p>In the years ahead the role played by cities will be under greater scrutiny than ever before. Cities are, after all, the beating heart of business, commerce, trade and society. They cover 3% of the earth's land surface yet they are responsible for <a href="https://www.un.org/sustainabledevelopment/cities/" rel="noopener noreferrer" target="_blank">more than 70%</a> of all carbon emissions. Cities are where the need for integrated energy solutions, backed up by ambitious policy and urban planning, will be critical if the world is to move towards net-zero emissions in the years ahead.</p><ul class="ee-ul"></ul><p>The private sector has a role to play. Over the past few years, companies and industries have begun to ask how they can play their part. Many in the energy sector are on a mission to help customers decarbonize within their own sectors, businesses, communities and homes. But how could that work for cities?</p>
<h3>Co-visioning</h3><p>While every city has unique needs, five are common to building sustainable and smarter cities of the future. These are mobility, energy, environment, urban planning and living. And it is a mix of these elements that is required to develop integrated solutions. To better understand the different needs, convening a diverse set of city stakeholders is key. This I would like to describe as co-visioning.</p><p>For example, in May 2018 the city of Paris set an ambition to be carbon-neutral by 2050. This ambition is not without challenges. Rising levels of income and wealth inequality, transport emissions and older and energy-inefficient building stock are among the challenges standing in the way of that goal.</p><p>In 2019, Shell, alongside <a href="https://leonard.vinci.com/en/" target="_blank">Leonard</a> (a foresight and innovation platform) and the Organisation for Economic Co-operation and Development (<a href="https://www.oecd.org/" target="_blank">OECD</a>), hosted a City Scenarios workshop in Paris. This event brought together 45 key stakeholders from across both public and private sectors and the wider community, who discussed how to collectively address and meet the objectives of the Paris Climate Action Plan, which aims to make Paris a carbon-neutral city by 2050.</p><p>The outcomes of this workshop led to a <a href="http://www.shell.com/parissketch" target="_blank">sketch that explores three scenarios</a>. Each describes different visions of the future for the Paris Metropole, while illustrating a pathway to 2050 and describes progress, or lack thereof, towards the goals of the Paris Climate Action Plan. A short description of each scenario is described in the visual below.</p>
<p><a href="https://www.shell.com/energy-and-innovation/the-energy-future/scenarios/scenario-sketches/sketch-paris-metropole-becoming-carbon-neutral.html#vanity-aHR0cHM6Ly93d3cuc2hlbGwuY29tL3Bhcmlzc2tldGNoLmh0bWw" target="_blank" rel="noopener noreferrer"><img alt="Three scenarios for the future of Paris" src="https://assets.weforum.org/editor/fikEqXUoihJyeI5QAOk5cFJ_lIVcKVXWz-21d0r2SJQ.png"></a>Three scenarios for the future of Paris (Image: Shell)</p><p>The purpose of this exploration was to guide the wisest possible choices and actions that should be taken now, to achieve the shared ambitions for the Paris region. Far from being a regular commercial opportunity, this instead looked to envision future scenarios and what customers' needs in the future could look like. This work has enabled us to better integrate solutions in the years ahead.</p>
<h3>Integrated solutions</h3><p>After understanding the needs, one approach to co-innovate solutions is to adopt a 'Living Lab' concept. In Singapore, we launched a <a href="https://www.shell.com/energy-and-innovation/the-energy-future/future-cities/shell-city-solutions.html#vanity-aHR0cHM6Ly93d3cuc2hlbGwuY29tL2NpdHlzb2x1dGlvbnMuaHRtbA" target="_blank" rel="noopener noreferrer">City Solutions Living Lab</a> to co-create and experiment with city stakeholders' innovative concepts, scenarios, technologies and business models in actual living environments.</p><p>The island city-state is forward thinking in its approach to energy transition. It has set ambitious targets to increase renewables, and announced that it plans to phase out petrol and diesel vehicles by 2040. With this shared vision, Shell partnered Singapore's Energy Market Authority (EMA) to jointly work on spurring the adoption of energy storage systems to support the deployment of more solar in Singapore. One ongoing project is to work with local enterprises to develop smart energy-management system solutions that integrate solar and storage to provide fast charging for electric vehicles at Shell service stations.</p><p>There is no one-size fits all solution. Starting from each city's needs, integrated solutions need to be innovated and delivered. This will require unprecedented collaboration between government, industry and society. But the urgency has never been greater. After all, making cities sustainable places to live and work for future generations will be imperative if the world is to meet the broader goals of the Paris Agreement and move closer to a net-zero emissions world.</p><p><em>To learn more, please visit the <a href="https://www.weforum.org/projects/systemic-efficiency" target="_blank" rel="noopener noreferrer">programme webpage</a> and see the recent report <a href="http://www3.weforum.org/docs/WEF_Net_Zero_Carbon_Cities_An_Integrated_Approach_2021.pdf" target="_blank" rel="noopener noreferrer">Net Zero Carbon Cities: An Integrated Approach</a>.</em></p><p>Reprinted with permission of the <a target="_blank" href="https://www.weforum.org/" rel="noopener noreferrer" style="">World Economic Forum</a>. Read the <a target="_blank" href="https://www.weforum.org/agenda/2021/02/cities-are-at-the-heart-of-our-journey-to-net-zero/" rel="noopener noreferrer" style="">original article</a>.</p>
Keep reading
Show less
Popular
