What is Big Think?  

We are Big Idea Hunters…

We live in a time of information abundance, which far too many of us see as information overload. With the sum total of human knowledge, past and present, at our fingertips, we’re faced with a crisis of attention: which ideas should we engage with, and why? Big Think is an evolving roadmap to the best thinking on the planet — the ideas that can help you think flexibly and act decisively in a multivariate world.

A word about Big Ideas and Themes — The architecture of Big Think

Big ideas are lenses for envisioning the future. Every article and video on bigthink.com and on our learning platforms is based on an emerging “big idea” that is significant, widely relevant, and actionable. We’re sifting the noise for the questions and insights that have the power to change all of our lives, for decades to come. For example, reverse-engineering is a big idea in that the concept is increasingly useful across multiple disciplines, from education to nanotechnology.

Themes are the seven broad umbrellas under which we organize the hundreds of big ideas that populate Big Think. They include New World Order, Earth and Beyond, 21st Century Living, Going Mental, Extreme Biology, Power and Influence, and Inventing the Future.

Big Think Features:

12,000+ Expert Videos

1

Browse videos featuring experts across a wide range of disciplines, from personal health to business leadership to neuroscience.

Watch videos

World Renowned Bloggers

2

Big Think’s contributors offer expert analysis of the big ideas behind the news.

Go to blogs

Big Think Edge

3

Big Think’s Edge learning platform for career mentorship and professional development provides engaging and actionable courses delivered by the people who are shaping our future.

Find out more
Close

Scientists Remove Extra Chromosome From Down Syndrome Line

November 10, 2012, 6:30 PM
Chromosomes%202

What's the Latest Development?

Researchers at the University of Washington have used a new medical procedure to remove the extra copy of chromosome 21 in cell cultures derived from a person affected by Down syndrome. The new technique is remarkable in its ability to completely remove the chromosome without affecting portions of the genetic code. "Gene therapy researchers have to be careful that their approaches do not cause gene toxicity," said Dr. David W. Russell. "This means, for example, that removal of a chromosome must not break or rearrange the remaining genetic code. This method shouldn't do that." 

What's the Big Idea?

Down syndrome is a genetic abnormality caused by a trisomy, or the triplication of a chromosome. Researchers hope that by removing the extra copy of chromosome 21 from cell cultures, new cell therapies will emerge for some of the blood-forming disorders that accompany Down syndrome. "Researcher could [also] contrast, for example, how the two cell lines formed brain nerve cells, to learn the effects of trisomy 21 on neuron development, which might offer insights into the lifelong cognitive impairments and adulthood mental decline of Down syndrome."

Photo credit: Shutterstock.com

 

 

Scientists Remove Extra Chr...

Newsletter: Share: