How Childhood Trauma Can Make You A Sick Adult
The Adverse Childhood Study found that survivors of childhood trauma are up to 5,000 percent more likely to attempt suicide, have eating disorders, or become IV drug users. Dr. Vincent Felitti, the study's founder, details this remarkable and powerful connection.
A renowned physician and researcher, Dr. Vincent J. Felitti is one of the world’s foremost experts on childhood trauma. Leading the charge in research into how adverse childhood experiences affect adults, he is co-principal investigator of the internationally recognized Adverse Childhood Experiences (ACE) Study, a long-term, in-depth, analysis of over 17,000 adults. Defying conventional belief, this study famously revealed a powerful relationship between our emotional experiences as children and our physical and mental health as adults. In fact, the ACE study shows that humans convert childhood traumatic emotional experiences into organic disease later in life. Revolutionary at its inception, Felitti’s groundbreaking research remains extremely relevant to today’s healthcare models.
Founder of the Department of Preventive Medicine for Kaiser Permanente, Felitti served as the chief of preventive medicine for over 25 years. Under Dr. Felitti's leadership, his department provided comprehensive medical evaluations to 1.1 million individuals, becoming the largest single-site medical evaluation facility in the western world. During this time, Felitti’s revolutionary health risk abatement programs incorporated weight loss, smoking cessation, stress management, and a wide range of cutting-edge efforts to reduce patient risk factors. Dr. Felitti also has served on advisory committees at the Institute of Medicine and the American Psychiatric Association. A noted expert on the genetic disease hemochromatosis, as well as obesity, he educates audiences around the country on these two very common, deadly maladies.
An engaging speaker, Felitti has traveled the world speaking with audiences and various policy leaders about his research. A well-versed medical expert, Felitti also uses his knowledge to speak out against domestic violence and other forms of childhood trauma. Drawing on his years of experience, he has become an important voice advocating for the wellbeing of children everywhere. While time may not heal all wounds, Felitti helps show audiences how we can understand these physical and mental traumas, and ultimately, prevent them.
Vincent Felitti: What we found in the ACE study involving seventeen-and-a-half thousand middle-class adults was that life experiences in childhood that are lost in time and then further protected by shame and by secrecy and by social taboos against inquiry into certain realms of human experience — that those life experiences play out powerfully and proportionately a half century later, in terms of emotional state, in terms of biomedical disease, in terms of life expectancy. In 1985, I first became interested in developmental life experiences in early childhood really by accident. In the major obesity program we were running, a young woman came into the program. She was 28 years old, and weighed 408 pounds, and asked us if we could help her with her problem. And in 51 weeks, we took her from 408 to 132. And we thought, well my god, we’ve got this problem licked. This is going to be a world-famous department here! She maintained her weight at 132 for several weeks, and then in one three-week period regained 37 pounds in three weeks, which I had not previously conceived as being physiologically possible. That was triggered by being sexually propositioned at work by a much older man, as she described him. And in short order, she was back over 400 pounds faster than she had lost the weight. I remember asking her why the extreme response. After initially claiming not to have any understanding of why the extreme response, ultimately she told me of a lengthy incest history with her grandfather, from age 10 to age 21. Ultimately it turned out that 55 percent of the people in our obesity program acknowledged a history of childhood sexual abuse. I mean, that obviously is not the only issue going on, but it was where we began. And as we went down that trail, then we discovered other forms of abuse, also growing up in massively dysfunctional households, et cetera. The ACE study was really designed to see whether these things existed at all in the general population, and if so, how did they play out over time?
We studied 10 categories of adverse life experience that were chosen because of their prevalence in the weight program: childhood sexual abuse; heavy-duty childhood physical abuse — I’m not talking spanking — um; major emotional abuse (recurrent humiliation); two categories of neglect; growing up in a home where one of the members of the household, uh, was chronically depressed, suicidal, mentally ill, or in the state hospital; growing up in a home without both biological parents; growing up in a home where, um, one of the members of your household was alcoholic or a drug user; growing up in a home where mother was beaten; growing up in a home where one of the members of your household was imprisoned during your childhood or adolescence. Those were the 10 categories. In a middle-class population, one in 11 people has experienced six or more of those adverse life experiences in childhood. So this is very common. Totally unrecognized. It was difficult for us to accept their commonness. But on the other hand, these are issues that most people never touch. And so who would know without routinely asking? But at a so-called ACE score of six, experiencing any six of the 10 categories that we studied, that person was 4,600 percent more likely to become an IV drug user than a person who had experienced none of those 10 categories. Okay? Now, you know, you think, you read the newspaper, the latest cancer scare of the week, prostate cancer or breast cancer increases 30 percent, and everyone goes nuts. I’m talking 4,600 percent increase. The same ACE score of six produces a likelihood of attempting suicide that is between 3,100 percent and 5,000 percent greater than the likelihood of suicide attempts in someone with none of those life experiences. So the power of this relationship is enormous.
So ultimately the question arises: How do life experiences in childhood end up with disease states a half century later? There are at least two big categories to account for that. One is through the use of various coping devices. One smokes to feel better; one overeats to feel better; one drinks to relax, et cetera. And those things carried out in heavy amounts have major destructive patterns, even though they may be immediately beneficial. The other broad category has to do with the effect of chronic major unrelieved stress on the workings of one’s brain and central nervous system. In recent years, this is relatively new; it’s become clear that chronic major unrelieved stress can produce the release of pro-inflammatory chemicals in a person’s body, and also can suppress immune system function. Of the 10 categories that we studied, any six of them produces a shortening in life expectancy of almost 20 years. The magnitude of this problem is so huge, and the complexity of dealing with it after the fact is so huge, that realistically, the only serious approach is going to have to involve primary prevention. No one knows how to do that, but it’s the right question to focus on.
The Adverse Childhood Study found that survivors of childhood trauma are up to 5,000 percent more likely to attempt suicide, have eating disorders, or become IV drug users. Dr. Vincent Felitti, the study's founder, details this remarkable and powerful connection.
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‘Designer baby’ book trilogy explores the moral dilemmas humans may soon create
How would the ability to genetically customize children change society? Sci-fi author Eugene Clark explores the future on our horizon in Volume I of the "Genetic Pressure" series.
- A new sci-fi book series called "Genetic Pressure" explores the scientific and moral implications of a world with a burgeoning designer baby industry.
- It's currently illegal to implant genetically edited human embryos in most nations, but designer babies may someday become widespread.
- While gene-editing technology could help humans eliminate genetic diseases, some in the scientific community fear it may also usher in a new era of eugenics.
Tribalism and discrimination
<p>One question the "Genetic Pressure" series explores: What would tribalism and discrimination look like in a world with designer babies? As designer babies grow up, they could be noticeably different from other people, potentially being smarter, more attractive and healthier. This could breed resentment between the groups—as it does in the series.</p><p>"[Designer babies] slowly find that 'everyone else,' and even their own parents, becomes less and less tolerable," author Eugene Clark told Big Think. "Meanwhile, everyone else slowly feels threatened by the designer babies."</p><p>For example, one character in the series who was born a designer baby faces discrimination and harassment from "normal people"—they call her "soulless" and say she was "made in a factory," a "consumer product." </p><p>Would such divisions emerge in the real world? The answer may depend on who's able to afford designer baby services. If it's only the ultra-wealthy, then it's easy to imagine how being a designer baby could be seen by society as a kind of hyper-privilege, which designer babies would have to reckon with. </p><p>Even if people from all socioeconomic backgrounds can someday afford designer babies, people born designer babies may struggle with tough existential questions: Can they ever take full credit for things they achieve, or were they born with an unfair advantage? To what extent should they spend their lives helping the less fortunate? </p>Sexuality dilemmas
<p>Sexuality presents another set of thorny questions. If a designer baby industry someday allows people to optimize humans for attractiveness, designer babies could grow up to find themselves surrounded by ultra-attractive people. That may not sound like a big problem.</p><p>But consider that, if designer babies someday become the standard way to have children, there'd necessarily be a years-long gap in which only some people are having designer babies. Meanwhile, the rest of society would be having children the old-fashioned way. So, in terms of attractiveness, society could see increasingly apparent disparities in physical appearances between the two groups. "Normal people" could begin to seem increasingly ugly.</p><p>But ultra-attractive people who were born designer babies could face problems, too. One could be the loss of body image. </p><p>When designer babies grow up in the "Genetic Pressure" series, men look like all the other men, and women look like all the other women. This homogeneity of physical appearance occurs because parents of designer babies start following trends, all choosing similar traits for their children: tall, athletic build, olive skin, etc. </p><p>Sure, facial traits remain relatively unique, but everyone's more or less equally attractive. And this causes strange changes to sexual preferences.</p><p>"In a society of sexual equals, they start looking for other differentiators," he said, noting that violet-colored eyes become a rare trait that genetically engineered humans find especially attractive in the series.</p><p>But what about sexual relationships between genetically engineered humans and "normal" people? In the "Genetic Pressure" series, many "normal" people want to have kids with (or at least have sex with) genetically engineered humans. But a minority of engineered humans oppose breeding with "normal" people, and this leads to an ideology that considers engineered humans to be racially supreme. </p>Regulating designer babies
<p>On a policy level, there are many open questions about how governments might legislate a world with designer babies. But it's not totally new territory, considering the West's dark history of eugenics experiments.</p><p>In the 20th century, the U.S. conducted multiple eugenics programs, including immigration restrictions based on genetic inferiority and forced sterilizations. In 1927, for example, the Supreme Court ruled that forcibly sterilizing the mentally handicapped didn't violate the Constitution. Supreme Court Justice Oliver Wendall Holmes wrote, "… three generations of imbeciles are enough." </p><p>After the Holocaust, eugenics programs became increasingly taboo and regulated in the U.S. (though some states continued forced sterilizations <a href="https://www.uvm.edu/~lkaelber/eugenics/" target="_blank">into the 1970s</a>). In recent years, some policymakers and scientists have expressed concerns about how gene-editing technologies could reanimate the eugenics nightmares of the 20th century. </p><p>Currently, the U.S. doesn't explicitly ban human germline genetic editing on the federal level, but a combination of laws effectively render it <a href="https://academic.oup.com/jlb/advance-article/doi/10.1093/jlb/lsaa006/5841599#204481018" target="_blank" rel="noopener noreferrer">illegal to implant a genetically modified embryo</a>. Part of the reason is that scientists still aren't sure of the unintended consequences of new gene-editing technologies. </p><p>But there are also concerns that these technologies could usher in a new era of eugenics. After all, the function of a designer baby industry, like the one in the "Genetic Pressure" series, wouldn't necessarily be limited to eliminating genetic diseases; it could also work to increase the occurrence of "desirable" traits. </p><p>If the industry did that, it'd effectively signal that the <em>opposites of those traits are undesirable. </em>As the International Bioethics Committee <a href="https://academic.oup.com/jlb/advance-article/doi/10.1093/jlb/lsaa006/5841599#204481018" target="_blank" rel="noopener noreferrer">wrote</a>, this would "jeopardize the inherent and therefore equal dignity of all human beings and renew eugenics, disguised as the fulfillment of the wish for a better, improved life."</p><p><em>"Genetic Pressure Volume I: Baby Steps"</em><em> by Eugene Clark is <a href="http://bigth.ink/38VhJn3" target="_blank">available now.</a></em></p>Archaeologists identify contents of ancient Mayan drug containers
Scientists use new methods to discover what's inside drug containers used by ancient Mayan people.
- Archaeologists used new methods to identify contents of Mayan drug containers.
- They were able to discover a non-tobacco plant that was mixed in by the smoking Mayans.
- The approach promises to open up new frontiers in the knowledge of substances ancient people consumed.
PARME staff archaeologists excavating a burial site at the Tamanache site, Mérida, Yucatan.
Credit: WSU
Ten “keys to reality” from a Nobel-winning physicist
To understand ourselves and our place in the universe, "we should have humility but also self-respect," Frank Wilczek writes in a new book.
Designer uses AI to bring 54 Roman emperors to life
It's hard to stop looking back and forth between these faces and the busts they came from.
- A quarantine project gone wild produces the possibly realistic faces of ancient Roman rulers.
- A designer worked with a machine learning app to produce the images.
- It's impossible to know if they're accurate, but they sure look plausible.
How the Roman emperors got faced
<a href="https://payload.cargocollective.com/1/6/201108/14127595/2K-ENGLISH-24x36-Educational_v8_WATERMARKED_2000.jpg" ><img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNDQ2NDk2MS9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYyOTUzMzIxMX0.OwHMrgKu4pzu0eCsmOUjybdkTcSlJpL_uWDCF2djRfc/img.jpg?width=980" id="775ca" class="rm-shortcode" data-rm-shortcode-id="436000b6976931b8320313478c624c82" data-rm-shortcode-name="rebelmouse-image" alt="lineup of emperor faces" data-width="1440" data-height="963" /></a>Credit: Daniel Voshart
<p>Voshart's imaginings began with an AI/neural-net program called <a href="https://www.artbreeder.com" target="_blank">Artbreeder</a>. The freemium online app intelligently generates new images from existing ones and can combine multiple images into…well, who knows. It's addictive — people have so far used it to generate nearly 72.7 million images, says the site — and it's easy to see how Voshart fell down the rabbit hole.</p><p>The Roman emperor project began with Voshart feeding Artbreeder images of 800 busts. Obviously, not all busts have weathered the centuries equally. Voshart told <a href="https://www.livescience.com/ai-roman-emperor-portraits.html" target="_blank" rel="noopener noreferrer">Live Science</a>, "There is a rule of thumb in computer programming called 'garbage in garbage out,' and it applies to Artbreeder. A well-lit, well-sculpted bust with little damage and standard face features is going to be quite easy to get a result." Fortunately, there were multiple busts for some of the emperors, and different angles of busts captured in different photographs.</p><p>For the renderings Artbreeder produced, each face required some 15-16 hours of additional input from Voshart, who was left to deduce/guess such details as hair and skin coloring, though in many cases, an individual's features suggested likely pigmentations. Voshart was also aided by written descriptions of some of the rulers.</p><p>There's no way to know for sure how frequently Voshart's guesses hit their marks. It is obviously the case, though, that his interpretations look incredibly plausible when you compare one of his emperors to the sculpture(s) from which it was derived.</p><p>For an in-depth description of Voshart's process, check out his posts on <a href="https://medium.com/@voshart/photoreal-roman-emperor-project-236be7f06c8f" target="_blank">Medium</a> or on his <a href="https://voshart.com/ROMAN-EMPEROR-PROJECT" target="_blank" rel="noopener noreferrer">website</a>.</p><p>It's fascinating to feel like you're face-to-face with these ancient and sometimes notorious figures. Here are two examples, along with some of what we think we know about the men behind the faces.</p>Caligula
<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNDQ2NDk4Mi9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTY3MzQ1NTE5NX0.LiTmhPQlygl9Fa9lxay8PFPCSqShv4ELxbBRFkOW_qM/img.jpg?width=980" id="7bae0" class="rm-shortcode" data-rm-shortcode-id="ce795c554490fe0a36a8714b86f55b16" data-rm-shortcode-name="rebelmouse-image" data-width="992" data-height="558" />One of numerous sculptures of Caligula, left
Credit: Rogers Fund, 1914/Wikimedia Commons/Daniel Voshart
<p><span style="background-color: initial;"><a href="https://en.wikipedia.org/wiki/Caligula" target="_blank">Caligula</a></span> was the third Roman Emperor, ruling the city-state from AD 37 to 41. His name was actually Gaius Caesar Augustus Germanicus — Caligula is a nickname meaning "Little Boot."</p><p>One of the reputed great madmen of history, he was said to have made a horse his consul, had conversations with the moon, and to have ravaged his way through his kingdom, including his three sisters. Caligula is known for extreme cruelty, terrorizing his subjects, and accounts suggest he would deliberately distort his face to surprise and frighten people he wished to intimidate.</p><p>It's <a href="https://www.history.com/news/7-things-you-may-not-know-about-caligula" target="_blank">not totally clear</a> if Caligula was as over-the-top as history paints him, but that hasn't stopped Hollywood from churning out some <a href="https://www.imdb.com/title/tt0080491/" target="_blank" rel="noopener noreferrer">howlers</a> in his name.</p><p>A 1928 journal, <a href="https://www.jstor.org/stable/4172009" target="_blank">Studies in Philology</a>, noted that contemporary descriptions of Caligula depicted him as having a "head misshapen, eyes and temples sunken," and "eyes staring and with a glare savage enough to torture." In some sculptures not shown above, his head <em>is</em> a bit acorn-shaped. </p>Nero
<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNDQ2NTAwMC9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTY1NTQ2ODU0NX0.AgYuQZzRQCanqehSI5UeakpxU8fwLagMc_POH7xB3-M/img.jpg?width=980" id="a8825" class="rm-shortcode" data-rm-shortcode-id="9e0593d79c591c97af4bd70f3423885e" data-rm-shortcode-name="rebelmouse-image" data-width="992" data-height="558" />One of numerous sculptures of Nero, left
Credit: Bibi_Saint-Pol/Wikimedia Commons/Daniel Voshart
<p>There's a good German word for the face of <a href="https://en.wikipedia.org/wiki/Nero" target="_blank" rel="noopener noreferrer">Nero</a>, that guy famous for fiddling as Rome burned. It's "<a href="https://www.urbandictionary.com/define.php?term=Backpfeifengesicht" target="_blank">backpfeifengesicht</a>." Properly named Nero Claudius Caesar Augustus Germanicus, he was Rome's fifth emperor. He ruled from AD 54 until his suicide in AD 68.</p><p>Another Germanicus-family gem, Nero's said to have murdered his own mother, Agrippa, as well as (maybe) his second wife. As for the fiddling, he <em>was</em> a lover of music and the arts, and there are stories of his charitability. And, oh yeah, he may have set the fire as an excuse to rebuild the city center, making it his own.</p><p>While it may not be the most historically sound means of assessing an historical personage, Voshart's imagining of Nero does suggest an over-indulged, entitled young man. Backpfeifengesicht.</p>This is your brain on political arguments
Debating is cognitively taxing but also important for the health of a democracy—provided it's face-to-face.
- New research at Yale identifies the brain regions that are affected when you're in disagreeable conversations.
- Talking with someone you agree with harmonizes brain regions and is less energetically taxing.
- The research involves face-to-face dialogues, not conversations on social media.
There are two kinds of identity politics. One is good. The other, very bad. | Jonathan Haidt
<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="6f0e52833af5d35adab591bb92d79f8e"><iframe type="lazy-iframe" data-runner-src="https://www.youtube.com/embed/l-_yIhW9Ias?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span><p>Unsurprisingly, harmonious synchronization of brain states occurred when volunteers agreed, similar to <a href="https://www.researchgate.net/publication/322764116_Creativity_and_Flow_in_Surgery_Music_and_Cooking_An_Interview_with_Neuroscientist_Charles_Limb" target="_blank">group flow</a>—the coordination of brain waves that hip-hop and jazz musicians (among others) experience when performing together. Coordination exceeds the social, into the neurological. As the team writes, "talking during agreement was characterized by increased activity in a social and attention network including right supramarginal gyrus, bilateral frontal eye-fields, and left frontopolar regions."</p><p>This contrasts with argumentative behavior, in which "the frontoparietal system including bilateral dorsolateral prefrontal cortex, left supramarginal gyrus, angular gyrus, and superior temporal gyrus showed increased activity while talking during disagreement."</p><p>Senior author Joy Hirsch notes that our brain is essentially a social processing network. The evolutionary success of humans is thanks to our ability to coordinate. Dissonance is exhausting. Overall, <a href="https://www.sciencedaily.com/releases/2021/01/210113090938.htm" target="_blank">she says</a>, "it just takes a lot more brain real estate to disagree than to agree," comparing arguments to a symphony orchestra playing different music. </p><p>As the team notes, language, visual, and social systems are all dynamically intertwined inside of our brain. For most of history, yelling at one another in comment sections was impossible. Arguments had to occur the old-fashioned way: while staring at the source of your discontent. </p>People of the "left-wing" side yell at a Trump supporter during a "Demand Free Speech" rally on Freedom Plaza on July 6, 2019 in Washington, DC.
Credit: Stephanie Keith/Getty Images
<p>Leading us to an interesting question: do the same brain regions fire when you're screaming with your fingers on your Facebook feed? Given the lack of visual feedback from the person on the other side of the argument, likely not—as it is unlikely that many people would argue in the same manner when face-to-face with a person on the other side of a debate. We are generally more civil in real life than on a screen.</p><p>The researchers point out that seeing faces causes complex neurological reactions that must be interpreted in real-time. For example, gazing into someone's eyes requires higher-order processing that must be dealt with during the moment. Your brain coordinates to make sense of the words being spoken <em>and</em> pantomimes being witnessed. This combination of verbal and visual processes are "generally associated with high-level cognitive and linguistic functions."</p><p>While arguing is more exhausting, it also sharpens your senses—when a person is present, at least. Debating is a healthy function of society. Arguments force you to consider other viewpoints and potentially come to different conclusions. As with physical exercise, which makes you stronger even though it's energetically taxing, disagreement propels societies forward.</p>In this study, every participant was forced to <em>listen</em> to the other person. As this research was focused on live interactions, it adds to the literature of cognitive processing during live interactions and offers insights into the cognitive tax of anger. Even anger is a net positive when it forces both sides to think through their thoughts and feelings on a matter. As social animals, we need that tension in our lives in order to grow. Yelling into the void of a comments section? Not so helpful. <p>--</p><p><em>Stay in touch with Derek on <a href="http://www.twitter.com/derekberes" target="_blank">Twitter</a> and <a href="https://www.facebook.com/DerekBeresdotcom" target="_blank">Facebook</a>. His most recent book is</em> "<em><a href="https://www.amazon.com/gp/product/B08KRVMP2M?pf_rd_r=MDJW43337675SZ0X00FH&pf_rd_p=edaba0ee-c2fe-4124-9f5d-b31d6b1bfbee" target="_blank" rel="noopener noreferrer">Hero's Dose: The Case For Psychedelics in Ritual and Therapy</a>."</em></p>