Self-Motivation
David Goggins
Former Navy Seal
Career Development
Bryan Cranston
Actor
Critical Thinking
Liv Boeree
International Poker Champion
Emotional Intelligence
Amaryllis Fox
Former CIA Clandestine Operative
Management
Chris Hadfield
Retired Canadian Astronaut & Author
Learn
from the world's big
thinkers
Start Learning

How Did Micro Medical Technology Get So Small?

Question: What was your first medical invention?

 

Dean Kamen: When I was still in my parents’ basement, busily making money doing our audio visual stuff, I had an older brother at the time who was off in medical school and he’s an extremely bright guy, doing both an MD and a PhD program, and his PhD work was in developing therapies for pediatrics, in fact neonatal cancer patients, babies with leukemia. And he was developing the drug therapy for this neonatal but they are so small. They weigh a couple of pounds. There was no practical equipment out there for him to deliver his therapy.

So, he dropped in the basement on a trip home from med school and whinning and complaining about his lack of equipment designed for babies. It wasn’t surprising to me that there is not a lot of equipment for babies because fortunately, they are not a very large piece of the medical population. Fortunately, old people get sick; babies don’t normally have that problem. But I get sit on the basement and imagine that I could build tiny, tiny, little drug delivery systems essentially using a syringe, for instance, as a whole base of drugs instead of an IV bottle.

So, I built for my brother some little devices that used the syringe as the reservoir and built some electronics in control systems that would allow him to program those things for drug delivery, for his research.

I think he was very proud of my stuff. I certainly wasn’t doing that as business. I was helping my brother. But he would take it to med school with him, and he ended up doing a little time at Harvard, where there are a lot of doctors up in Boston. And he ended up doing a residency in Yale where he met a lot of the adult docs. And one of these docs, at one point said, that little thing is so small it’s great that it sits in a nice set moving around with babies. But it’s so small, you could slap it on a belt or put it on a pocket of an adult who can work around getting chronic therapy for things that might dramatically improve their outcome. Like what? How about insulin for diabetics?

So, suddenly I took this core technology that I develop for this very rare disease--lots of people will never have to deal with pediatric cancer--and it would serve a very, very broad population of people walking around needing high insulin to deal with diabetes.

So we modified the pumps, we moved out of the basement. We started making lots of different pharmaceutical delivery systems. And we ended up building a nice company around that and until this day, we continue to build stuff for home dialysis, diabetes cares. He build lots of products related to helping people get both better therapy and live better lives simultaneously.

 

Conducted on: June 9, 2009.

 

 

Dean Kamen shares how he adapted one of his inventions, a tiny drug delivery system for neonatal cancer patients, for adults with other conditions.

The “new normal” paradox: What COVID-19 has revealed about higher education

Higher education faces challenges that are unlike any other industry. What path will ASU, and universities like ASU, take in a post-COVID world?

Photo: Luis Robayo/AFP via Getty Images
Sponsored by Charles Koch Foundation
  • Everywhere you turn, the idea that coronavirus has brought on a "new normal" is present and true. But for higher education, COVID-19 exposes a long list of pernicious old problems more than it presents new problems.
  • It was widely known, yet ignored, that digital instruction must be embraced. When combined with traditional, in-person teaching, it can enhance student learning outcomes at scale.
  • COVID-19 has forced institutions to understand that far too many higher education outcomes are determined by a student's family income, and in the context of COVID-19 this means that lower-income students, first-generation students and students of color will be disproportionately afflicted.
Keep reading Show less

Creativity: The science behind the madness

Human brains evolved for creativity. We just have to learn how to access it.

Videos
  • An all-star cast of Big Thinkers—actors Rainn Wilson and Ethan Hawke; composer Anthony Brandt; neuroscientists David Eagleman, Wendy Suzuki, and Beau Lotto; and psychologist Scott Barry Kaufman—share how they define creativity and explain how our brains uniquely evolved for the phenomenon.
  • According to Eagleman, during evolution there was an increase in space between our brain's input and output that allows information more time to percolate. We also grew a larger prefrontal cortex which "allows us to simulate what ifs, to separate ourselves from our location in space and time and think about possibilities."
  • Scott Barry Kaufman details 3 brain networks involved in creative thinking, and Wendy Suzuki busts the famous left-brain, right-brain myth.

Dinosaur bone? Meteorite? These men's wedding bands are a real break from boredom.

Manly Bands wanted to improve on mens' wedding bands. Mission accomplished.

Sex & Relationships
  • Manly Bands was founded in 2016 to provide better options and customer service in men's wedding bands.
  • Unique materials include antler, dinosaur bones, meteorite, tungsten, and whiskey barrels.
  • The company donates a portion of profits to charity every month.
Keep reading Show less

What if Middle-earth was in Pakistan?

Iranian Tolkien scholar finds intriguing parallels between subcontinental geography and famous map of Middle-earth.

Image: Mohammad Reza Kamali, reproduced with kind permission
Strange Maps
  • J.R.R. Tolkien hinted that his stories are set in a really ancient version of Europe.
  • But a fantasy realm can be inspired by a variety of places; and perhaps so is Tolkien's world.
  • These intriguing similarities with Asian topography show that it may be time to 'decolonise' Middle-earth.
Keep reading Show less

How #Unity2020 plans to end the two-party system, bring back Andrew Yang

The proposal calls for the American public to draft two candidates to lead the executive branch: one from the center-left, the other from the center-right.

Photo by David Becker/Getty Images
Politics & Current Affairs
  • The #Unity2020 plan was recently outlined by Bret Weinstein, a former biology professor, on the Joe Rogan Experience.
  • Weinstein suggested an independent ticket for the 2020 presidential election: Andrew Yang and former U.S. Navy Admiral William McRaven.
  • Although details of the proposal are sparse, surveys suggest that many Americans are cynical and frustrated with the two-party system.
Keep reading Show less
Quantcast