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Vaping-related lung damage resembles mustard gas injuries
The safest bet is to listen to health officials and avoid vaping products.
- American health officials have so far recorded more than 1,000 vaping-related hospitalizations, and at least 18 people have died.
- These cases seem to be linked to black-market vaping products, not mainstream ones available in stores.
- The results of the new report suggest that it's the chemical compounds within the vaping products — not the oil itself — that's causing hospitalizations.
Update Wednesday, November 20, 2019: Since March, vaping-related illness has landed over 2,000 individuals in hospitals nationwide, and at least 39 of those people have died.
Health officials have so far recorded about 1,080 cases of vaping-related lung injuries in the U.S., according to the Centers for Diseases Control and Prevention. At least 18 people have died across 15 states, and concern (and in some cases hysteria) continues to grow over the health effects of vaping. Still, it remains unclear exactly what part or chemical in vaping products is harming people, and no single product or ingredient has been linked to the hospitalizations (although some cases have been traced back to black-market vaping cartridges).
Last week, researchers at Mayo Clinic published a report in the New England Journal of Medicine describing the lung damage in some of these cases. The researchers — experts in lung pathology who examined lung tissue samples from 17 patients around the U.S. — said the tissue looked like it had suffered chemical burns, or even exposure to poisons like mustard gas, a chemical weapon from World War I.
"All 17 of our cases show a pattern of injury in the lung that looks like a toxic chemical exposure, a toxic chemical fume exposure, or a chemical burn injury," Dr. Brandon T. Larsen, a surgical pathologist at the Mayo Clinic in Scottsdale, Ariz., told The New York Times. "To be honest, they look like the kind of change you would expect to see in an unfortunate worker in an industrial accident where a big barrel of toxic chemicals spills, and that person is exposed to toxic fumes and there is a chemical burn in the airways."
Image source: Larsen et al., New England Journal of Medicine
Larsen and his colleagues reported finding cell death and tissue damage in the airways, and within the lungs. This damage causes tissues to swell as the body tries to repair itself, but that swelling makes it difficult or impossible to breathe.
"The lung is not very functional when it's been damaged and is trying to repair itself," Larsen said. "There's no reserve left while the body tries to heal itself, so people will be really sick, on a ventilator because they can't get enough oxygen in, or carbon dioxide out […] Some patients will not recover, and will end up dying."
The results suggest that it's the chemical compounds within vape juice — and not necessarily the oils (vitamin E acetate, for example) – that are damaging the lungs. Of the 17 patients examined, all had vaped, and 12 had vaped marijuana or cannabis oils.
"So maybe we need to look more closely at the chemical compounds, and not just oils, but the chemical constituents, to figure out which ones are injurious," Larsen told the Times.
The myriad of vaping products, both legal and illegal, makes it difficult to know what's going on.
"One of the problems with vaping is that there's so many products and materials and substances in the market," Larsen said in a video published by Mayo Clinic. "With tobacco, there was only one culprit, and so it was very easy to get a good sense of exactly what the acute and long-term changes were on the lung from doing that. [...] The same is true with marijuana smoking, in the traditional sense. It's a single substance, and the types of changes are relatively predictable over time. But the sky's the limit with vaping."
For now, the safest bet is to listen to health officials and avoid vaping products, the researchers said.
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Construction of the $500 billion dollar tech city-state of the future is moving ahead.
- The futuristic megacity Neom is being built in Saudi Arabia.
- The city will be fully automated, leading in health, education and quality of life.
- It will feature an artificial moon, cloud seeding, robotic gladiators and flying taxis.
The Red Sea area where Neom will be built:
Saudi Arabia Plans Futuristic City, "Neom" (Full Promotional Video)<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="c646d528d230c1bf66c75422bc4ccf6f"><iframe type="lazy-iframe" data-runner-src="https://www.youtube.com/embed/N53DzL3_BHA?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span>
Are we genetically inclined for superstition or just fearful of the truth?
- From secret societies to faked moon landings, one thing that humanity seems to have an endless supply of is conspiracy theories. In this compilation, physicist Michio Kaku, science communicator Bill Nye, psychologist Sarah Rose Cavanagh, skeptic Michael Shermer, and actor and playwright John Cameron Mitchell consider the nature of truth and why some groups believe the things they do.
- "I think there's a gene for superstition, a gene for hearsay, a gene for magic, a gene for magical thinking," argues Kaku. The theoretical physicist says that science goes against "natural thinking," and that the superstition gene persists because, one out of ten times, it actually worked and saved us.
- Other theories shared include the idea of cognitive dissonance, the dangerous power of fear to inhibit critical thinking, and Hollywood's romanticization of conspiracies. Because conspiracy theories are so diverse and multifaceted, combating them has not been an easy task for science.
A growing body of research suggests COVID-19 can cause serious neurological problems.
- The new study seeks to track the health of 50,000 people who have tested positive for COVID-19.
- The study aims to explore whether the disease causes cognitive impairment and other conditions.
- Recent research suggests that COVID-19 can, directly or indirectly, cause brain dysfunction, strokes, nerve damage and other neurological problems.
Brain images of a patient with acute demyelinating encephalomyelitis.
COVID-19 and the brain<p>A growing body of research reveals alarming neurological complications among COVID-19 patients. On Wednesday, for example, researchers from University College London published a <a href="https://academic.oup.com/brain/article/doi/10.1093/brain/awaa240/5868408" target="_blank">study</a> in the journal Brain that describes how some patients have suffered temporary brain dysfunction, strokes, nerve damage, and other neurological problems concurrent with COVID-19.</p><p>Some patients suffered brain inflammation as a result of a rare disease called acute disseminated encephalomyelitis, which can cause numbness, seizures, and confusion. One patient in the study even hallucinated monkeys and lions in her home.</p>
Photo by Mario Tama/Getty Images<p>A separate study published in the <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198407/" target="_blank">Journal of Clinical Neuroscience</a> notes that some COVID-19 patients have also suffered neurological complications like impaired consciousness and acute cerebrovascular disease. The study notes that past viruses like MERS and SARS also seemed to cause neurological problems.</p><p>A troubling finding among this growing body of research is that some patients seem to suffer neurological damage even when respiratory symptoms aren't obvious. Additionally, scientists aren't sure whether damage from the disease will be permanent.</p><p style="margin-left: 20px;">"Given that the disease has only been around for a matter of months, we might not yet know what long-term damage COVID-19 can cause," Dr. Ross Paterson, joint first author of the University College London study, said in a <a href="https://www.eurekalert.org/pub_releases/2020-07/ucl-iid070620.php" target="_blank">press release</a>. "Doctors needs to be aware of possible neurological effects, as early diagnosis can improve patient outcomes."</p><p>If you've been diagnosed with COVID-19 and want to enroll in the study, visit <a href="https://www.cambridgebrainsciences.com/studies/covid-brain-study" target="_blank">cambridgebrainsciences.com/studies/covid-brain-study</a>.</p>
Coronavirus layoffs are a glimpse into our automated future. We need to build better education opportunities now so Americans can find work in the economy of tomorrow.