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The shocking, forgotten history of cretinism
Now an insult, 'cretin' was the medical term for a debilitating disease endemic in the Alps until the early 20th century.
- Until about a century ago, 'cretinism' was endemic throughout large parts of the Alps.
- Sufferers often had a visibly enlarged thyroid gland, and in the worst cases were severely retarded.
- Although 'goiter belts' in North America and Europe have been eradicated, the disease remains common throughout the world.
Cretins with goiter, Styria (Austria), early 19th century.
Image: Oesterreichs Tibur (1819), public domain. Found here on Wikimedia Commons.
How do you make Captain Haddock swear like the drunken sailor he is, without R-rating the comic that stars his much milder-mannered friend Tintin?
Eventually Hergé, Tintin's spiritual father, found the answer. Whenever Haddock verbally exploded, his stream of invective was colorful rather than off-color. The captain merely shouted scientific and esoteric terms at the victims of his frequent displeasure.
So when Haddock let out "crétin des Alpes" ('Alpine cretin') in the original French-language version of The Seven Crystal Balls (serialised from 1943), the expression was sufficiently obscure to be inoffensive, its topographic specificity only adding to the humorous effect (1).
Yet the word 'cretin' has a very real, very shocking and at that time still very recent history, and indeed a link to the Alps. When Haddock used the term, the age-old blight of cretinism had been erased only a few decades earlier. But the relative isolation of the sufferers, and the pitiful nature of their suffering, had already wiped the disease from public memory.
Map of the geographic distribution of 'cretinism and idiocy in France'. White: less than 2 'cretins or idiots' per 1,000 inhabitants. Lightest grey: at least two. Middle shade: at least three. Darkest grey: at least five.
Image from p. 96 of the report on goiters and cretins by Dr Jules Baillarger (1873), public domain. Found here on the page Culture, Histoire et Patrimoine de Passy.
From the 18th century onwards, travellers exploring the then remote Alps for their natural beauty were often horrified by the region's human geography. Among the inhabitants of some secluded valleys, they found many who suffered from physical deformities and mental retardation.
In the Guide du Voyageur en Suisse (1788), Thomas Martyn observed: "These imbeciles, known as 'cretins', are plentiful (in the Valais region of Switzerland). Their body resembles that of a dwarf, they appear misshapen and sombre, their minds are devoid of all activity. Their smile only indicates that the cretin is merely a living animal."
The most prominent physical symptom was a so-called 'goiter' (2) – a greatly enlarged thyroid gland, bulging forward from the neck. Other physical symptoms included dwarfism (with adult sufferers as short as 1 meter (3 ft 3 in), loss of hair, thick skin, enlarged tongue and/or belly, and muscle impairment sometimes severe enough to prevent walking or even standing.
Additionally, cretinism could manifest as cognitive impairment, from slight to severe mental retardation. Some sufferers were so afflicted they couldn't speak or take basic care of themselves.
'Joseph le crétin': photograph by Eugene Trutat (1840-1910).
Image preserved by the Muséum de Toulouse public domain. Found here at Wikimedia Commons.
Although not yet by that name, 'cretinism' was known to the ancients and was described by Roman writers. However, because its most severe manifestations were limited to isolated mountainous regions, it was long underreported – and misdiagnosed. Early medical hypotheses blamed stagnant valley air, bad water, 'geological toxicity,' or inbreeding for the congenital disorder.
The actual cause of cretinism is iodine deficiency, which is why the current preferred term is 'congenital iodine deficiency syndrome' or CIDS. Iodine is a mineral that is needed for the production of thyroid hormones, without which the human body's metabolism can't properly function.
Iodine is most abundantly present in the oceans and is transported to land by rain. However, it is not uniformly present in soil. It is most notably absent from mountainous and other inland regions, especially those subject to frequent flooding.
Plants grown in these regions will also be iodine-deficient, and will locals eating only locally-sourced foods. The soil in some Alpine regions is severely iodine deficient. In combination with dietary monoculture, this explains the abundance of cretinism in the region.
Geographic distribution of goiters throughout Europe in 1883: not just in the Alps or Pyrenees, but also notably throughout western Germany, northern Italy, Austria and Britain.
Image: Bircher (1883), public domain. Found here on the page Culture, Histoire et Patrimoine de Passy.
From the 18th century, 'cretinism' became the common term for the disease in French medical texts. The word's origin is uncertain but may derive from the French 'chrétien' ('Christian'), a common greeting in the French Alps – or perhaps a term used as a reminder of the basic humanity of the sufferers. Other possible etymologies:
- 'creta', Latin for 'chalk', because of the sufferers' pale appearance;
- 'cretira', a local word for 'creature'; or
- 'cretine', a French word for soil deposited by flowing water, based on the assumption that poor soil caused the disease.
Around 1850, the French state identified around 20,000 of its citizens as 'cretins' and around 100,000 as sufferers from the goiter, in 24 of its around 90 departments – especially in its mountainous regions, in both the Alps and Pyrenees.
In the 19th century, so-called 'goiter belts' were identified in Europe and North America: regions where the most visible symptom of cretinism was relatively common – even if the severity of the illness was usually much less than in the worst-afflicted parts of the Alps.
Originally a neutral term, 'cretin' fell out of use as an official medical term (in both English and French) in the early 20th century due to pejoration, i.e. the downgrading of a word's meaning (3), and its use is now shunned.
Map showing the relationship between iodine deficiencies (grey) and goiter occurrence (shaded) in the United States. Date unknown - probably early 20th century.
Image: Armed Forces Institute of Pathology, public domain. Found here at JC Durbant.
With the growth of trade in the 19th century, the dependence on locally grown produce throughout Europe diminished, greatly reducing the occurrence of the disease. Around that time, Swiss doctors were the first to propose iodine deficiency as the genuine cause of cretinism. However, it took three generations for this theory to be proven – if action had been taken immediately, about 50,000 sufferers would have been saved the disorder's debilitating effects.
From 1922, Switzerland began to distribute iodised cooking salt, as well as iodised lozenges for children. Almost immediately, new cases of cretinism ceased to occur. At present, more than 120 countries have mandatory programs for adding iodine to food staples (typically salt, but also flour, rice or oil).
In developed countries, cretinism has almost completely been wiped out, thanks to standard screening for thyroid function on newborn babies. Iodine deficiency is still a sufficiently serious problem to remain the most common preventable cause of brain damage in new-borns and young children today. If the condition is found, its symptoms can be suppressed by lifelong administration of thyroxine.
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(1) Haddock later recycles the insult in other geographic contexts: "crétin de l'Himalaya" (Tintin in Tibet) and "crétin des Balkans" (The Calculus Affair).
(2) Derived via Provençal and French from the Latin gutturus, 'throat'.
(3) A similar process occurred with 'lunatic' and 'spastic', no longer neutral descriptors, now adjectives with a decidedly negative connotation.
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Evolution doesn't clean up after itself very well.
- An evolutionary biologist got people swapping ideas about our lingering vestigia.
- Basically, this is the stuff that served some evolutionary purpose at some point, but now is kind of, well, extra.
- Here are the six traits that inaugurated the fun.
The plica semilunaris<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8xOTA5NjgwMS9vcmlnaW4ucG5nIiwiZXhwaXJlc19hdCI6MTYxMTgyMzg1NX0.ZY8qmhtoZfbRMAqrNnmbgyk7GLabglx_9lBq3PKcy7g/img.png?width=980" id="99882" class="rm-shortcode" data-rm-shortcode-id="68e8758894b0359c6ef61b2c158832b2" data-rm-shortcode-name="rebelmouse-image" />
The human eye in alarming detail. Image source: Henry Gray / Wikimedia commons<p>At the inner corner of our eyes, closest to the nasal ridge, is that little pink thing, which is probably what most of us call it, called the caruncula. Next to it is the plica semilunairs, and it's what's left of a third eyelid that used to — ready for this? — blink horizontally. It's supposed to have offered protection for our eyes, and some birds, reptiles, and fish have such a thing.</p>
Palmaris longus<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8xOTA5NjgwNy9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYzMzQ1NjUwMn0.dVor41tO_NeLkGY9Tx46SwqhSVaA8HZQmQAp532xLxA/img.jpg?width=980" id="879be" class="rm-shortcode" data-rm-shortcode-id="970e9c15f3c3d846dde05e2b2c6ebf12" data-rm-shortcode-name="rebelmouse-image" />
Palmaris longus muscle. Image source: Wikimedia commons<p> We don't have much need these days, at least most of us, to navigate from tree branch to tree branch. Still, about 86 percent of us still have the wrist muscle that used to help us do it. To see if you have it, place the back of you hand on a flat surface and touch your thumb to your pinkie. If you have a muscle that becomes visible in your wrist, that's the palmaris longus. If you don't, consider yourself more evolved (just joking).</p>
Darwin's tubercle<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8xOTA5NjgxMi9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTY0ODUyNjA1MX0.8RuU-OSRf92wQpaPPJtvFreOVvicEwn39_jnbegiUOk/img.jpg?width=980" id="687a0" class="rm-shortcode" data-rm-shortcode-id="b38a957408940673ccc744f0f6828d18" data-rm-shortcode-name="rebelmouse-image" />
Darwin's tubercle. Image source: Wikimedia commons<p> Yes, maybe the shell of you ear does feel like a dried apricot. Maybe not. But there's a ridge in that swirly structure that's a muscle which allowed us, at one point, to move our ears in the direction of interesting sounds. These days, we just turn our heads, but there it is.</p>
Goosebumps<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8xOTA5NzMxNC9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYyNzEyNTc2Nn0.aVMa5fsKgiabW5vkr7BOvm2pmNKbLJF_50bwvd4aRo4/img.jpg?width=980" id="d8420" class="rm-shortcode" data-rm-shortcode-id="f735418322b34382dcd882299c9ccc48" data-rm-shortcode-name="rebelmouse-image" />
Goosebumps. Photo credit: Tyler Olson via Shutterstock<p>It's not entirely clear what purpose made goosebumps worth retaining evolutionarily, but there are two circumstances in which they appear: fear and cold. For fear, they may have been a way of making body hair stand up so we'd appear larger to predators, much the way a cat's tail puffs up — numerous creatures exaggerate their size when threatened. In the cold, they may have trapped additional heat for warmth.</p>
Tailbone<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8xOTA5NzMxNi9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYxMDMzMDc3N30.p9BEtkf3-PV3EtDSQMUGUeopsimiCHUagx97P4f8IBw/img.jpg?width=980" id="e8ab8" class="rm-shortcode" data-rm-shortcode-id="0063ce99bdd22fbebe1279244b87935c" data-rm-shortcode-name="rebelmouse-image" />
Coccyx. Image source: decade3d-anatomy online via Shutterstock<p>Way back, we had tails that probably helped us balance upright, and was useful moving through trees. We still have the stump of one when we're embryos, from 4–6 weeks, and then the body mostly dissolves it during Weeks 6–8. What's left is the coccyx.</p>
The palmar grasp reflex<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8xOTA5NzMyMC9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYzNjY0MDY5NX0.OSwReKLmNZkbAS12-AvRaxgCM7zyukjQUaG4vmhxTtM/img.jpg?width=980" id="8804c" class="rm-shortcode" data-rm-shortcode-id="45469ca5ee5f43433a782f7d4ac0a440" data-rm-shortcode-name="rebelmouse-image" />
Palmar reflex activated! Photo credit: Raul Luna on Flickr<p> You've probably seen how non-human primate babies grab onto their parents' hands to be carried around. We used to do this, too. So still, if you touch your finger to a baby's palm, or if you touch the sole of their foot, the palmar grasp reflex will cause the hand or foot to try and close around your finger.</p>
Other people's suggestions<p>Amir's followers dove right in, offering both cool and questionable additions to her list. </p>
Fangs?<blockquote class="twitter-tweet" data-conversation="none" data-lang="en"><p lang="en" dir="ltr">Lower mouth plate behind your teeth. Some have protruding bone under the skin which is a throw back to large fangs. Almost like an upsidedown Sabre Tooth.</p>— neil crud (@neilcrud66) <a href="https://twitter.com/neilcrud66/status/1085606005000601600?ref_src=twsrc%5Etfw">January 16, 2019</a></blockquote> <script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>
Hiccups<blockquote class="twitter-tweet" data-conversation="none" data-lang="en"><p lang="en" dir="ltr">Sure: <a href="https://t.co/DjMZB1XidG">https://t.co/DjMZB1XidG</a></p>— Stephen Roughley (@SteBobRoughley) <a href="https://twitter.com/SteBobRoughley/status/1085529239556968448?ref_src=twsrc%5Etfw">January 16, 2019</a></blockquote> <script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>
Hypnic jerk as you fall asleep<blockquote class="twitter-tweet" data-conversation="none" data-lang="en"><p lang="en" dir="ltr">What about when you “jump” just as you’re drifting off to sleep, I heard that was a reflex to prevent falling from heights.</p>— Bann face (@thebanns) <a href="https://twitter.com/thebanns/status/1085554171879788545?ref_src=twsrc%5Etfw">January 16, 2019</a></blockquote> <script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script> <p> This thing, often called the "alpha jerk" as you drop into alpha sleep, is properly called the hypnic jerk,. It may actually be a carryover from our arboreal days. The <a href="https://www.livescience.com/39225-why-people-twitch-falling-asleep.html" target="_blank" data-vivaldi-spatnav-clickable="1">hypothesis</a> is that you suddenly jerk awake to avoid falling out of your tree.</p>
Nails screeching on a blackboard response?<blockquote class="twitter-tweet" data-conversation="none" data-lang="en"><p lang="en" dir="ltr">Everyone hate the sound of fingernails on a blackboard. It's _speculated_ that this is a vestigial wiring in our head, because the sound is similar to the shrill warning call of a chimp. <a href="https://t.co/ReyZBy6XNN">https://t.co/ReyZBy6XNN</a></p>— Pet Rock (@eclogiter) <a href="https://twitter.com/eclogiter/status/1085587006258888706?ref_src=twsrc%5Etfw">January 16, 2019</a></blockquote> <script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>
Ear hair<blockquote class="twitter-tweet" data-conversation="none" data-lang="en"><p lang="en" dir="ltr">Ok what is Hair in the ears for? I think cuz as we get older it filters out the BS.</p>— Sarah21 (@mimix3) <a href="https://twitter.com/mimix3/status/1085684393593561088?ref_src=twsrc%5Etfw">January 16, 2019</a></blockquote> <script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>
Nervous laughter<blockquote class="twitter-tweet" data-lang="en"><p lang="en" dir="ltr">You may be onto something. Tooth-bearing with the jaw clenched is generally recognized as a signal of submission or non-threatening in primates. Involuntary smiling or laughing in tense situations might have signaled that you weren’t a threat.</p>— Jager Tusk (@JagerTusk) <a href="https://twitter.com/JagerTusk/status/1085316201104912384?ref_src=twsrc%5Etfw">January 15, 2019</a></blockquote> <script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>
Um, yipes.<blockquote class="twitter-tweet" data-conversation="none" data-lang="en"><p lang="en" dir="ltr">Sometimes it feels like my big toe should be on the side of my foot, was that ever a thing?</p>— B033? K@($ (@whimbrel17) <a href="https://twitter.com/whimbrel17/status/1085559016011563009?ref_src=twsrc%5Etfw">January 16, 2019</a></blockquote> <script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>
A clever new study definitively measures how long it takes for quantum particles to pass through a barrier.
- Quantum particles can tunnel through seemingly impassable barriers, popping up on the other side.
- Quantum tunneling is not a new discovery, but there's a lot that's unknown about it.
- By super-cooling rubidium particles, researchers use their spinning as a magnetic timer.
When it comes to weird behavior, there's nothing quite like the quantum world. On top of that world-class head scratcher entanglement, there's also quantum tunneling — the mysterious process in which particles somehow find their way through what should be impenetrable barriers.
Exactly why or even how quantum tunneling happens is unknown: Do particles just pop over to the other side instantaneously in the same way entangled particles interact? Or do they progressively tunnel through? Previous research has been conflicting.
That quantum tunneling occurs has not been a matter of debate since it was discovered in the 1920s. When IBM famously wrote their name on a nickel substrate using 35 xenon atoms, they used a scanning tunneling microscope to see what they were doing. And tunnel diodes are fast-switching semiconductors that derive their negative resistance from quantum tunneling.
Nonetheless, "Quantum tunneling is one of the most puzzling of quantum phenomena," says Aephraim Steinberg of the Quantum Information Science Program at Canadian Institute for Advanced Research in Toronto to Live Science. Speaking with Scientific American he explains, "It's as though the particle dug a tunnel under the hill and appeared on the other."
Steinberg is a co-author of a study just published in the journal Nature that presents a series of clever experiments that allowed researchers to measure the amount of time it takes tunneling particles to find their way through a barrier. "And it is fantastic that we're now able to actually study it in this way."
Frozen rubidium atoms
Image source: Viktoriia Debopre/Shutterstock/Big Think
One of the difficulties in ascertaining the time it takes for tunneling to occur is knowing precisely when it's begun and when it's finished. The authors of the new study solved this by devising a system based on particles' precession.
Subatomic particles all have magnetic qualities, and they spin, or "precess," like a top when they encounter an external magnetic field. With this in mind, the authors of the study decided to construct a barrier with a magnetic field, causing any particles passing through it to precess as they did so. They wouldn't precess before entering the field or after, so by observing and timing the duration of the particles' precession, the researchers could definitively identify the length of time it took them to tunnel through the barrier.
To construct their barrier, the scientists cooled about 8,000 rubidium atoms to a billionth of a degree above absolute zero. In this state, they form a Bose-Einstein condensate, AKA the fifth-known form of matter. When in this state, atoms slow down and can be clumped together rather than flying around independently at high speeds. (We've written before about a Bose-Einstein experiment in space.)
Using a laser, the researchers pusehd about 2,000 rubidium atoms together in a barrier about 1.3 micrometers thick, endowing it with a pseudo-magnetic field. Compared to a single rubidium atom, this is a very thick wall, comparable to a half a mile deep if you yourself were a foot thick.
With the wall prepared, a second laser nudged individual rubidium atoms toward it. Most of the atoms simply bounced off the barrier, but about 3% of them went right through as hoped. Precise measurement of their precession produced the result: It took them 0.61 milliseconds to get through.
Reactions to the study
Scientists not involved in the research find its results compelling.
"This is a beautiful experiment," according to Igor Litvinyuk of Griffith University in Australia. "Just to do it is a heroic effort." Drew Alton of Augustana University, in South Dakota tells Live Science, "The experiment is a breathtaking technical achievement."
What makes the researchers' results so exceptional is their unambiguity. Says Chad Orzel at Union College in New York, "Their experiment is ingeniously constructed to make it difficult to interpret as anything other than what they say." He calls the research, "one of the best examples you'll see of a thought experiment made real." Litvinyuk agrees: "I see no holes in this."
As for the researchers themselves, enhancements to their experimental apparatus are underway to help them learn more. "We're working on a new measurement where we make the barrier thicker," Steinberg said. In addition, there's also the interesting question of whether or not that 0.61-millisecond trip occurs at a steady rate: "It will be very interesting to see if the atoms' speed is constant or not."
So far, 30 student teams have entered the Indy Autonomous Challenge, scheduled for October 2021.
- The Indy Autonomous Challenge will task student teams with developing self-driving software for race cars.
- The competition requires cars to complete 20 laps within 25 minutes, meaning cars would need to average about 110 mph.
- The organizers say they hope to advance the field of driverless cars and "inspire the next generation of STEM talent."
Indy Autonomous Challenge<p>Completing the race in 25 minutes means the cars will need to average about 110 miles per hour. So, while the race may end up being a bit slower than a typical Indy 500 competition, in which winners average speeds of over 160 mph, it's still set to be the fastest autonomous race featuring full-size cars.</p><p style="margin-left: 20px;">"There is no human redundancy there," Matt Peak, managing director for Energy Systems Network, a nonprofit that develops technology for the automation and energy sectors, told the <a href="https://www.post-gazette.com/business/tech-news/2020/06/01/Indy-Autonomous-Challenge-Indy-500-Indianapolis-Motor-Speedway-Ansys-Aptiv-self-driving-cars/stories/202005280137" target="_blank">Pittsburgh Post-Gazette</a>. "Either your car makes this happen or smash into the wall you go."</p>
Illustration of the Indy Autonomous Challenge
Indy Autonomous Challenge<p>The Indy Autonomous Challenge <a href="https://www.indyautonomouschallenge.com/rules" target="_blank">describes</a> itself as a "past-the-post" competition, which "refers to a binary, objective, measurable performance rather than a subjective evaluation, judgement, or recognition."</p><p>This competition design was inspired by the 2004 DARPA Grand Challenge, which tasked teams with developing driverless cars and sending them along a 150-mile route in Southern California for a chance to win $1 million. But that prize went unclaimed, because within a few hours after starting, all the vehicles had suffered some kind of critical failure.</p>
Indianapolis Motor Speedway
Indy Autonomous Challenge<p>One factor that could prevent a similar outcome in the upcoming race is the ability to test-run cars on a virtual racetrack. The simulation software company Ansys Inc. has already developed a model of the Indianapolis Motor Speedway on which teams will test their algorithms as part of a series of qualifying rounds.</p><p style="margin-left: 20px;">"We can create, with physics, multiple real-life scenarios that are reflective of the real world," Ansys President Ajei Gopal told <a href="https://www.wsj.com/articles/autonomous-vehicles-to-race-at-indianapolis-motor-speedway-11595237401?mod=e2tw" target="_blank">The Wall Street Journal</a>. "We can use that to train the AI, so it starts to come up to speed."</p><p>Still, the race could reveal that self-driving cars aren't quite ready to race at speeds of over 110 mph. After all, regular self-driving cars already face enough logistical and technical roadblocks, including <a href="https://www.bbc.com/news/technology-53349313#:~:text=Tesla%20will%20be%20able%20to,no%20driver%20input%2C%20he%20said." target="_blank">crumbling infrastructure, communication issues</a> and the <a href="https://bigthink.com/paul-ratner/would-you-ride-in-a-car-thats-programmed-to-kill-you" target="_self">fateful moral decisions driverless cars will have to make in split seconds</a>.</p>But the Indy Autonomous Challenge <a href="https://static1.squarespace.com/static/5da73021d0636f4ec706fa0a/t/5dc0680c41954d4ef41ec2b2/1572890638793/Indy+Autonomous+Challenge+Ruleset+-+v5NOV2019+%282%29.pdf" target="_blank">says</a> its main goal is to advance the industry, by challenging "students around the world to imagine, invent, and prove a new generation of automated vehicle (AV) software and inspire the next generation of STEM talent."