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‘No one should be doing the ketogenic diet,’ says top U.S. cardiologist

Ketosis is known to work wonders in terms of short-term weight loss. But what about the diet’s effects over the long term?

Maybe it's time to start eating bread again. (Image: Creative Commons/Big Think)

  • The ketogenic diet is one of the latest dietary fads to sweep the U.S., promising rapid weight loss, enhanced brain function and sustained energy throughout the day.
  • These effects are achieved by replacing high-carb foods with fatty, protein-rich foods that will eventually put the body in ketosis: a natural metabolic state in which the body burns fat for fuel instead of carbohydrates.
  • Ketosis is known to work wonders for short-term weight loss. But what about the diet's effects over the long term?

According to Dr. Kim Williams, former president of the American College of Cardiology, no one should adopt the ketogenic diet over the long term—unless weight loss is more important than lifespan.

“I like the idea, the basic concept: you change your dietary habits and you change something," Williams told Plant Based News. “Unfortunately, the science of it is wrong. If all you wanted was short-term weight loss—and short-term could be a year or two—if that's all you're looking for, great."

Williams' argument is based on a 2013 systematic review of 17 studies that found low-carbohydrate diets to be associated with an increased chance of death, with particularly increased risks to cardiovascular health.

“So I was talking about that and making sure everyone was hearing about that, and then there was one the Journal of the American Heart Association published a few years later that isolated the people who had had a heart attack in the past, the cardiology population that we're seeing, and they were doing a ketogenic diet," Williams told Plant Based News. “It was a 53 percent increase in mortality. No one should be doing this."

The authors of the 2013 systematic review offered similar advice:

“Given the facts that low-carbohydrate diets are likely unsafe and that calorie restriction has been demonstrated to be effective in weight loss regardless of nutritional composition, it would be prudent not to recommend low-carbohydrate diets for the time being. Further detailed studies to evaluate the effect of protein source are urgently needed."

The ketogenic diet can pose long-term health risks because “low-carbohydrate diets tend to result in reduced intake of fiber and fruits, and increased intake of protein from animal sources, cholesterol and saturated fat, all of which are risk factors for mortality" and cardiovascular disease, wrote the authors of the review.


What foods can you and can't you eat on the keto diet?

It's worth noting that the review focused on low-carbohydrate diets, which are not always ketogenic. To be sure, there are balanced ways to adopt the ketogenic diet, and it can beneficial to some. In addition to its proven weight-loss effects that can be especially helpful for obese people, the diet is also a proven treatment for children with epilepsy. That's because the state of ketosis produces a natural chemical called decanoic acid, which can reduce seizures.

But if you're looking for a safe diet that you can rely on over the long term, you might follow the advice given by Dr. Marcelo Campos in an article posted on the Harvard Health Blog:

“Instead of engaging in the next popular diet that would last only a few weeks to months (for most people that includes a ketogenic diet), try to embrace change that is sustainable over the long term. A balanced, unprocessed diet, rich in very colorful fruits and vegetables, lean meats, fish, whole grains, nuts, seeds, olive oil, and lots of water seems to have the best evidence for a long, healthier, vibrant life."

How accountability at work can transform your organization

If you don't practice accountability at work you're letting the formula for success slip right through your hands.

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  • What is accountability? It's a tool for improving performance and, once its potential is thoroughly understood, it can be leveraged at scale in any team or organization.
  • In this lesson for leaders, managers, and individuals, Shideh Sedgh Bina, a founding partner of Insigniam and the editor-in-chief of IQ Insigniam Quarterly, explains why it is so crucial to success.
  • Learn to recognize the mindset of accountable versus unaccountable people, then use Shideh's guided exercise as a template for your next post-project accountability analysis—whether that project was a success or it fell short, it's equally important to do the reckoning.

What if Middle-earth was in Pakistan?

Iranian Tolkien scholar finds intriguing parallels between subcontinental geography and famous map of Middle-earth

Could this former river island in the Indus have inspired Tolkien to create Cair Andros, the ship-shaped island in the Anduin river?

Image: Mohammad Reza Kamali, reproduced with kind permission
Strange Maps
  • J.R.R. Tolkien himself hinted that his stories are set in a really ancient version of Europe.
  • But a fantasy realm can be inspired by a variety of places; and perhaps so is Tolkien's world.
  • These intriguing similarities with Asian topography show that it may be time to 'decolonise' Middle-earth.
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Giant whale sharks have teeth on their eyeballs

The ocean's largest shark relies on vision more than previously believed.

An eight-metre-long Whale shark swims with other fish at the Okinawa Churaumi Aquarium on February 26, 2010 in Motobu, Okinawa, Japan.

Photo by Koichi Kamoshida/Getty Images
Surprising Science
  • Japanese researchers discovered that the whale shark has "tiny teeth"—dermal denticles—protecting its eyes from abrasion.
  • They also found the shark is able to retract its eyeball into the eye socket.
  • Their research confirms that this giant fish relies on vision more than previously believed.
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A massive star has mysteriously vanished, confusing astronomers

A gigantic star makes off during an eight-year gap in observations.

Image source: ESO/L. Calçada
Surprising Science
  • The massive star in the Kinsman Dwarf Galaxy seems to have disappeared between 2011 and 2019.
  • It's likely that it erupted, but could it have collapsed into a black hole without a supernova?
  • Maybe it's still there, but much less luminous and/or covered by dust.

A "very massive star" in the Kinman Dwarf galaxy caught the attention of astronomers in the early years of the 2000s: It seemed to be reaching a late-ish chapter in its life story and offered a rare chance to observe the death of a large star in a region low in metallicity. However, by the time scientists had the chance to turn the European Southern Observatory's (ESO) Very Large Telescope (VLT) in Paranal, Chile back around to it in 2019 — it's not a slow-turner, just an in-demand device — it was utterly gone without a trace. But how?

The two leading theories about what happened are that either it's still there, still erupting its way through its death throes, with less luminosity and perhaps obscured by dust, or it just up and collapsed into a black hole without going through a supernova stage. "If true, this would be the first direct detection of such a monster star ending its life in this manner," says Andrew Allan of Trinity College Dublin, Ireland, leader of the observation team whose study is published in Monthly Notices of the Royal Astronomical Society.

So, em...

Between astronomers' last look in 2011 and 2019 is a large enough interval of time for something to happen. Not that 2001 (when it was first observed) or 2019 have much meaning, since we're always watching the past out there and the Kinman Dwarf Galaxy is 75 million light years away. We often think of cosmic events as slow-moving phenomena because so often their follow-on effects are massive and unfold to us over time. But things happen just as fast big as small. The number of things that happened in the first 10 millionth of a trillionth of a trillionth of a trillionth of a second after the Big Bang, for example, is insane.

In any event, the Kinsman Dwarf Galaxy, or PHL 293B, is far way, too far for astronomers to directly observe its stars. Their presence can be inferred from spectroscopic signatures — specifically, PHL 293B between 2001 and 2011 consistently featured strong signatures of hydrogen that indicated the presence of a massive "luminous blue variable" (LBV) star about 2.5 times more brilliant than our Sun. Astronomers suspect that some very large stars may spend their final years as LBVs.

Though LBVs are known to experience radical shifts in spectra and brightness, they reliably leave specific traces that help confirm their ongoing presence. In 2019 the hydrogen signatures, and such traces, were gone. Allan says, "It would be highly unusual for such a massive star to disappear without producing a bright supernova explosion."

The Kinsman Dwarf Galaxy, or PHL 293B, is one of the most metal-poor galaxies known. Explosive, massive, Wolf-Rayet stars are seldom seen in such environments — NASA refers to such stars as those that "live fast, die hard." Red supergiants are also rare to low Z environments. The now-missing star was looked to as a rare opportunity to observe a massive star's late stages in such an environment.

Celestial sleuthing

In August 2019, the team pointed the four eight-meter telescopes of ESO's ESPRESSO array simultaneously toward the LBV's former location: nothing. They also gave the VLT's X-shooter instrument a shot a few months later: also nothing.

Still pursuing the missing star, the scientists acquired access to older data for comparison to what they already felt they knew. "The ESO Science Archive Facility enabled us to find and use data of the same object obtained in 2002 and 2009," says Andrea Mehner, an ESO staff member who worked on the study. "The comparison of the 2002 high-resolution UVES spectra with our observations obtained in 2019 with ESO's newest high-resolution spectrograph ESPRESSO was especially revealing, from both an astronomical and an instrumentation point of view."

Examination of this data suggested that the LBV may have indeed been winding up to a grand final sometime after 2011.

Team member Jose Groh, also of Trinity College, says "We may have detected one of the most massive stars of the local Universe going gently into the night. Our discovery would not have been made without using the powerful ESO 8-meter telescopes, their unique instrumentation, and the prompt access to those capabilities following the recent agreement of Ireland to join ESO."

Combining the 2019 data with contemporaneous Hubble Space Telescope (HST) imagery leaves the authors of the reports with the sense that "the LBV was in an eruptive state at least between 2001 and 2011, which then ended, and may have been followed by a collapse into a massive BH without the production of an SN. This scenario is consistent with the available HST and ground-based photometry."

Or...

A star collapsing into a black hole without a supernova would be a rare event, and that argues against the idea. The paper also notes that we may simply have missed the star's supernova during the eight-year observation gap.

LBVs are known to be highly unstable, so the star dropping to a state of less luminosity or producing a dust cover would be much more in the realm of expected behavior.

Says the paper: "A combination of a slightly reduced luminosity and a thick dusty shell could result in the star being obscured. While the lack of variability between the 2009 and 2019 near-infrared continuum from our X-shooter spectra eliminates the possibility of formation of hot dust (⪆1500 K), mid-infrared observations are necessary to rule out a slowly expanding cooler dust shell."

The authors of the report are pretty confident the star experienced a dramatic eruption after 2011. Beyond that, though:

"Based on our observations and models, we suggest that PHL 293B hosted an LBV with an eruption that ended sometime after 2011. This could have been followed by
(1) a surviving star or
(2) a collapse of the LBV to a BH [black hole] without the production of a bright SN, but possibly with a weak transient."

Future of Learning

Changing the way we grade students could trigger a wave of innovation

How students apply what they've learned is more important than a letter or number grade.

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