Robert F. Kennedy
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John F. Kennedy appointed his brother Attorney General in 1961. 

Nicolas Cage
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The nephew of Francis Ford Coppola changed his name to avoid charges of nepotism. 

Two Presidents "for the Price of One"
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Opponents derisively referred to the Clintons as "co-presidents."

Tori Spelling
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The actress's father was also the producer of Beverly Hills 90210. 

Michael Powell, et al in George W. Bush's Administration
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Helen Thomas called the administration "a family affair, reeking of nepotism."