//Should be placed in the header of every page. This won't fire any events

In 20 Years, Couples Won't Have Sex to Reproduce, Says Genetics Expert

Will we be building a better world or a more homogeneous one?


The 1932 dystopian masterpiece Brave New World opens with a tour of the Central London Hatchery and Conditioning Centre, where genetically engineered humans are bred in five distinct categories, and brainwashed into accepting their fate, pigeonholed for the rest of their lives, in a caste system made possible by reproductive and genetic science.

Lay on top of this the succulent morsel of possibility, or perhaps the bait toward chaos. Such advances hold much promise. Imagine a world with fewer diseases. Not only could hereditary diseases be eliminated, but those genes which make conditions like Alzheimer’s, heart disease, diabetes, and cancer more likely could be erased as well. Our future world could be a place where people are more capable, healthier, better looking, and less prone to disease.

But in this same world, if we move too close to homogeny, we may eliminate the complex processes and random happenstances which produce a Mozart, a Da Vinci, or an Einstein, those outliers who change things for the better. So what is this technology, and how are we navigate the ethical and legal morass these capabilities create?

Henry T. Greely is both brave and informed enough to tackle this subject in a new book with a modest title, The End of Sex and the Future of Human Reproduction. As a professor of genetics, and the chair of the biomedical ethics committee at Stanford, Greely is an expert on such technologies, along with the ethical and legal challenges they pose. He argues that in as little as two to four decades, couples in developed countries will stop have sex for reproductive purposes and turn to science instead.

In vitro fertilization. Soon fertility science will be operating at a whole new level.

Greely contends that the process made to supplant natural conception will be free of charge—though that remains to be seen. Certain revolutionary techniques including stem cell research and genetics allow this to be possible. These and other new technologies and methods are poised to dramatically improve preimplantation genetic diagnosis (PGD), in vitro fertilization (IVF), and many more procedures. Really, this is about taking existing technology and scaling up.

We already use preimplantation genetic diagnosis (PGD) to detect a few disease-causing genes. Thousands of embryos undergo the procedure each year. Yet, it is expensive and cumbersome. But Greely sees a day where we will be able to sequence all of the 6.4 billion base pair genome of an embryo, quickly and inexpensively, what he calls “Easy PGD.”

Imagine a couple wanting to have a baby. They see the fertility specialist at a clinic, provide genetic material such as sperm or skin cells, and return sometime later. “The DNA of the resulting embryos will then be sequenced and carefully analyzed before decisions are made about which embryo or embryos to transfer to a womb for possible development,” Greely writes. “Prospective parents will be told as much as they wish to know about the genetic makeup of dozens of embryos, and they will pick one or two for implantation, gestation, and birth.” Besides the advantages of eliminating certain diseases, “It will be safe, lawful, and free.”

Preimplantation genetic diagnosis (PGD).

Greely describes the process like this, “Parents will get the embryos grouped by categories. One category will be very severe, untreatable, nasty diseases. This will affect one to two per cent of embryos. A second category would contain other diseases. The third will be a cosmetic category, including the person’s body shape, eye and hair color, whether the hair goes white early. We don’t know much about this yet, but we will.”

Behavioral characteristics come last. It won’t be possible to say, “This child is in the top one per cent of intelligence.” Yet, Greely believes it will be possible to say, “This child has a 60 per cent chance of being in the top half” of their graduating class. The cost savings on the healthcare system due to the decreased number of patients with hereditary diseases would be enormous. Some of these savings could be siphoned to widespread reproductive medicine, making the whole thing cost-effective and accessible.

Because of this, Greely predicts that those who make babies the old fashioned way, particularly in countries with socialized medicine may become stigmatized, since they would drive up the cost of healthcare. In a sense, it would also lead to more equality, as same sex couples could create a child that is genetically their own. It might also lead to some horrific results. “What if a woman decided to make eggs from herself and sperm from herself, and then transfer them to her own uterus?" posited Greely. Though it is unlikely, it could occur.

In vitro fertilization, along with “Easy PGD,” may replace sex as our method of reproduction.

Of course, people will still have sex for enjoyment, to grow closer to their partner, and for the health benefits. But Greely foresees the day when science makes sex for reproduction obsolete. And what about the moral and ethical quandaries? Greely in addition to being a scientist is a law expert. He says sometimes lawyers lay out the facts for the client and let them decide. He sees this book as that selfsame gesture. “I have some views about ways we might want to regulate Easy PGD, but they are tentative, based on glimpses and guesses of the future...”

This ability to steer human reproduction is becoming ever more possible. As this technology starts coming online, the future Huxley predicted comes ever closer to the realm of possibility. Of course, just like any new technology, it all depends on how it is being used. How can we develop the ethical and legal superstructure to ensure a better, more disease-free world, without being ensnared in a homogeneous or dystopian one? The truth is, no one really knows.

To learn more about designer babies click here: 

3D printing might save your life one day. It's transforming medicine and health care.

What can 3D printing do for medicine? The "sky is the limit," says Northwell Health researcher Dr. Todd Goldstein.

Northwell Health
Sponsored by Northwell Health
  • Medical professionals are currently using 3D printers to create prosthetics and patient-specific organ models that doctors can use to prepare for surgery.
  • Eventually, scientists hope to print patient-specific organs that can be transplanted safely into the human body.
  • Northwell Health, New York State's largest health care provider, is pioneering 3D printing in medicine in three key ways.
Keep reading Show less

Neuroprosthetics and deep brain stimulation: Two big neuroscience breakthroughs

Neuroscience is working to conquer some of the human body's cruelest conditions: Paralysis, brain disease, and schizophrenia.

  • Neuroscience and engineering are uniting in mind-blowing ways that will drastically improve the quality of life for people with conditions like epilepsy, paralysis or schizophrenia.
  • Researchers have developed a brain-computer interface the size of a baby aspirin that can restore mobility to people with paralysis or amputated limbs. It rewires neural messages from the brain's motor cortex to a robotic arm, or reroutes it to the person's own muscles.
  • Deep brain stimulation is another wonder of neuroscience that can effectively manage brain conditions like epilepsy, Parkinson's, and may one day mitigate schizophrenia so people can live normal, independent lives.
Keep reading Show less

Why the south of Westeros is the north of Ireland

As Game of Thrones ends, a revealing resolution to its perplexing geography.

Image: YouTube / Doosh
Strange Maps
  • The fantasy world of Game of Thrones was inspired by real places and events.
  • But the map of Westeros is a good example of the perplexing relation between fantasy and reality.
  • Like Britain, it has a Wall in the North, but the map only really clicks into place if you add Ireland.
Keep reading Show less

Why it’s hard to tell when high-class people are incompetent

A recent study gives new meaning to the saying "fake it 'til you make it."

Surprising Science
  • The study involves four experiments that measured individuals' socioeconomic status, overconfidence and actual performance.
  • Results consistently showed that high-class people tend to overestimate their abilities.
  • However, this overconfidence was misinterpreted as genuine competence in one study, suggesting overestimating your abilities can have social advantages.
Keep reading Show less
//This will actually fire event. Should be called after consent was verifed