from the world's big
How to vaccinate the world’s most vulnerable? Build global partnerships.
Pfizer's partnerships strengthen their ability to deliver vaccines in developing countries.
Pfizer Corporate Responsibility develops programs that help expand global access to medicines by providing direct assistance to underserved populations. Our initiatives include providing product donations and steep discounts that help patients access the medicine they need. We also collaborate with Pfizer business teams and nonprofit organizations to help shape sustainable business models that address affordability and the vast differences in economies around the world.
- Community healthcare workers face many challenges in their work, including often traveling far distances to see their clients
- Pfizer is helping to drive the UN's sustainable development goals through partnerships.
- Pfizer partnered with AMP and the World Health Organization to develop a training program for healthcare workers.
Community healthcare workers are often the only point of contact with the health system in many underserved areas in the developing world. These noble public servants work within the community to bring health coverage closer to people who need it. Millions of babies around the world are at risk every day from vaccine preventable diseases and many of them live in very remote communities. This means that health care workers must sometimes travel long distances over mountains, across desserts and through rivers while carrying vaccine coolers.
These are some of the reasons why Pfizer is proud to partner with organizations that share a vision of increasing the health and well-being of children around the world. Susan Silbermann, Global President of Pfizer Vaccines, recently sat down with Big Think to discuss how the company is helping to improve vaccine access in developing countries.
Pfizer is helping to improve vaccine access
The constraints people face in other countries requires companies to develop more novel and innovative approaches to help improve vaccine access.
So the question for Pfizer was: Tell us what innovating a vaccine means to you?
Silbermann brought a vial to show Big Think what innovation looks like.
"This tiny vial is an incredible testament to scientific innovation. Until 2017, it provided one dose to vaccinate one child. But now it provides four doses and can vaccinate four children. By combining multiple doses into one vial we have reduced the storage space and the shipping requirements."
Innovations like this multi-dose vial are just the beginning of making it easier to get vaccines to children. Here are a few facts that Pfizer wants to help change.
- Sub-saharan Africa bears nearly 25% of the disease burden in the world.
- It only has 3% of the global health workers.
The critical role of health care workers in the developing world
A health care worker administers a vaccine in Malawi.
Photo: Courtesy of Pfizer.
When Pfizer's new multi-dose vial (MDV) became available in 2017 in Gavi countries, it was a priority to ensure health care workers were properly trained. For this, Pfizer partnered up with the AMP and the World Health Organization to develop a pneumococcal conjugate refresher course and new training program for the multi-dose vial.
As part of the partnership program, Pfizer developed a "train the trainer" model that is a tiered system of training. For example, "master trainers" will go on to train the next round of health care workers.Last year, Pfizer trained over 27,000 health care workers across 15 different countries. And this year, it's extended the program to an additional nine countries with the goal of reaching an additional 17,000 new health care workers by the end of the year.
A future dedicated to vaccine development
The overall impact vaccines are having on global public health are astounding. It's been estimated that vaccinations have prevented 26 million cases of childhood infections in the last decade alone.
Right behind clean water, immunizations are the most important health investment we have. Pfizer employees are passionate about vaccine development because they know it will translate into a tremendous public health impact.
Once logistical barriers and other obstacles are overcome, Pfizer believes that we will be working toward building a better future in communities around the world. One the best ways to remove barriers is through working with and supporting partners.
Why partnerships matter
Pfizer supports many projects that work to empower and equip community health workers. It recognizes that supporting health care workers is a critical part of achieving universal health coverage.
Silbermann talked with Big Think about making sure vaccines get to where they are needed.
"We have to make sure that vaccines get to those who need it. I have often said that our job doesn't end when we make a vaccine and ship it to a distribution center. What good is a vaccine if it isn't reaching the people who need it the most?"
Pfizer is a strategic partner of AMP Health (Aspen Management Partnership for Health), a cross sector, public private partnership to strengthen healthcare systems. AMP Health partners with Ministries of Health to help grow community health and immunization programs by providing leadership and management training and has worked in Ghana, Kenya, Malawi, Sierra Leone, and Zambia.
National governments in Sub-Saharan Africa are committed to deploying thousands of community health workers, but often don't have the strategic, managerial, or financial skills to run a large-scale program.
Pfizer believes that professional, supported community health workers play a critical role in reaching underserved populations and that partnering with organizations like AMP Health advances this objective.
The unsung heroes
Vaccines must stay refrigerated as they travel and be stored at very specific temperatures until they are used. Health care workers often worry about the vaccine refrigerators which can be old and if they were to break down the quality of the vaccines could be at risk.
Silbermann told us a story about how a healthcare worker in Ghana ensured vaccines were available in her clinic.
"Let me tell you a story about a healthcare worker in Ghana that we recently met. She works in a clinic in a small village in the Ho region of Ghana which is approximately three hours north of the capital. In her clinic, there is no electricity or running water. These two elements are critical to ensure safe and effective use of medicines. For example, vaccines need to be stored at a specific temperature to maintain their effectiveness and therefore are stored in fridges which are powered by electricity.
"Instead of storing the vaccines in her clinic, the healthcare worker travels one hour each way on the bus to get fresh vaccines and transport them in a cooler. She then works all day at the clinic administering these vaccines and seeing mothers, children and babies. Without the dedication of healthcare workers like this one in Ghana it is very likely that communities of children would not have the opportunity to be vaccinated."
Why is Pfizer so committed to vaccines?
Pfizer colleagues are passionate about vaccine development and innovation because they know it can translate into a tremendous public health impact. Immunization not only saves lives and improves health, it also unlocks the potential of a community—a vaccinated community is not only healthier, research has shown it is stronger and more productive.
Silbermann left us with this thought:
"When I think about the future, I know we can make a significant difference by ensuring that no logistical issue is an obstacle to a child getting vaccinated. But we can't do it alone. We need to work together to build on our experiences and capabilities to make the world a healthier place to live."
Here's what it takes to get vaccines from the lab to the field
Pandemic rumors and information overload make separating fact from fancy difficult, putting people's health and lives at risk.
The dark side of the information age<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yMzU1NzYwMi9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYxNjE3MzY3Nn0.0HveQP16MbMkj9HXE8miohSHXETOak7oFDtBdXtE7lM/img.jpg?width=1245&coordinates=0%2C400%2C0%2C256&height=700" id="60d48" class="rm-shortcode" data-rm-shortcode-id="9085c1a7d5b3f81344c3002acdf1df68" data-rm-shortcode-name="rebelmouse-image" />
A South Korean church became a viral hotspot after church officials sprayed a salt water "cure" in congregants mouths, without disinfecting the nozzle between uses.
The cure for bad information is good<div class="rm-shortcode" data-media_id="e0tfZ3YB" data-player_id="FvQKszTI" data-rm-shortcode-id="601aa46855087a4dfcf02a67a160e0c4"> <div id="botr_e0tfZ3YB_FvQKszTI_div" class="jwplayer-media" data-jwplayer-video-src="https://content.jwplatform.com/players/e0tfZ3YB-FvQKszTI.js"> <img src="https://cdn.jwplayer.com/thumbs/e0tfZ3YB-1920.jpg" class="jwplayer-media-preview" /> </div> <script src="https://content.jwplatform.com/players/e0tfZ3YB-FvQKszTI.js"></script> </div> <p><strong></strong><strong></strong>That doesn't mean we are defenseless. The best cure for rumors, stigma, and conspiracy theories is good, evidence-based information. We just have to know how to recognize it when we find it. Unfortunately, that's difficult in the center of the infodemic vortex.</p><p>"Information overload is incredibly anxiety-provoking—which is true even when the information is accurate," Jaimie Meyer, a Yale Medicine infectious diseases specialist, <a href="https://www.yalemedicine.org/stories/covid-19-infodemic/" target="_blank">told <em>Yale Medicine</em></a>. "But here, if people get the wrong information from unreliable sources, we may have more trouble slowing the spread of the virus. And we can't afford to get this wrong."</p><p>In their study, the researchers concluded that governments and health agencies should study the patterns of pandemic rumors, track the misinformation, and develop communication strategies to circumvent these messages. </p><p>In the <em>Yale Medicine </em>article, Meyer provides advice for helping individuals deal with information overload. She recommends looking at data and graphs carefully, considering how individual studies connect with established facts, and considering the whole story (not just the eye-catching headline). </p><p>When it comes to garnering information from social media, proceed with caution.</p><p>"Everything looks the same on Twitter," Meyer said. "When you have a tweet from Anthony Fauci, MD, director of the National Association of Allergy and Infectious Diseases, next to a tweet that says the opposite thing from a celebrity or some random person—and they all appear similar, you have to weigh the credibility of your sources." </p><p>She recommends following health agencies like <a href="https://twitter.com/who?lang=en" target="_blank" rel="noopener noreferrer dofollow">the WHO</a>, <a href="https://twitter.com/CDCgov?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Eauthor" target="_blank" rel="noopener noreferrer dofollow">the Centers for Disease Control and Prevention</a>, and your local and state health agencies. When you come across a pandemic rumor or something that seems suspect, you can double-check it against these authoritative sources, such as the WHO's <a href="https://www.who.int/emergencies/diseases/novel-coronavirus-2019/advice-for-public/myth-busters" target="_blank" rel="noopener noreferrer dofollow">COVID-19 mythbusters page</a>. And if you find yourself stressing out over the news and your social media feed, <a href="https://bigthink.com/mind-brain/mental-health-activities-coronavirus-lockdown" target="_self" rel="dofollow">take a mental break</a>.</p><p>We all would like a return to some form of normalcy, but that return will not emanate from a miracle cure. It will be a slow, steady course of handwashing, social distancing, and learning to navigate the infodemic.</p>
Carbon locked in soils can be emitted by bacteria.Turning up the heat on them releases more carbon.
- A new study shows that an increase in temperature can increase the amount of carbon released by the soil.
- This is in line with previous studies, though this one demonstrates a larger increase than the older experiments.
- The risk is that increasing temperatures cause a positive feedback loop.
The dirty details of an aggravated carbon cycle<div class="rm-shortcode" data-media_id="CabkeAzx" data-player_id="FvQKszTI" data-rm-shortcode-id="169377c88f392a86f6c42180b74820a5"> <div id="botr_CabkeAzx_FvQKszTI_div" class="jwplayer-media" data-jwplayer-video-src="https://content.jwplatform.com/players/CabkeAzx-FvQKszTI.js"> <img src="https://cdn.jwplayer.com/thumbs/CabkeAzx-1920.jpg" class="jwplayer-media-preview" /> </div> <script src="https://content.jwplatform.com/players/CabkeAzx-FvQKszTI.js"></script> </div> <p>There is a lot of carbon in the dirt. The world's soil contains more carbon than the atmosphere, all the plants, or all the animals<a href="https://blogs.ei.columbia.edu/2018/02/21/can-soil-help-combat-climate-change/" target="_blank"></a>. A third of this trove of carbon resides in the soils of the <a href="https://www.sciencetimes.com/articles/26866/20200813/tropical-soils-highly-sensitive-climate-change.htm" target="_blank">tropics</a>. Under normal circumstances, this works as a carbon <a href="https://earthobservatory.nasa.gov/features/CarbonCycle" target="_blank">sink</a>, keeping carbon in storage and out of the atmosphere. Some of this carbon is used by bacteria in the soil to provide the building blocks of new microbes. They expel surplus carbon into the atmosphere in the form of carbon dioxide. </p><p>Many of these microbes are known to be more active when exposed to higher temperatures. To determine what this could mean for carbon emissions, a team from The University of Edenborough and the Smithsonian Tropical Research Institute turned up the heat in tropical soils to see what would happen. </p><p>The researchers went to an undisturbed plot of forest on Barro Colorado Panama, the home of the Smithsonian's Tropical Research Institute. They placed heating rods just over a meter into the soil and turned up the heat, warming the earth by four degrees centigrade. They then measured the carbon emissions from the heated ground and another nearby patch left at ambient temperature. These measurements covered two years.</p><p>Their findings, published in <a href="https://www.nature.com/articles/s41586-020-2566-4" target="_blank">Nature</a>, show that the heated soil emitted 55% more carbon than the control plot<a href="https://www.sciencedaily.com/releases/2020/08/200812144102.htm" target="_blank" rel="noopener noreferrer dofollow"></a>. <br> <br> Study lead author Andrew Nottingham commented on these findings to the <a href="https://phys.org/news/2020-08-global-tropical-soils-leak-carbon.html" target="_blank" rel="noopener noreferrer dofollow">AFP</a>. "Carbon held in tropical soils is more sensitive to warming than previously recognized. Even a small increase in respiration from tropical forest soils could have a large effect on atmospheric CO<sub>2</sub> concentrations, with consequences for global climate."</p><p>You can probably also spot the potential feedback loop here: If the global temperature increases too much, more carbon will be released from tropical soils, which then increase the greenhouse effect, which causes global temperatures to rise. </p>
Once is happenstance, twice is a coincidence, thrice is evidence of a pattern.<div class="rm-shortcode" data-media_id="8PLWDgcM" data-player_id="FvQKszTI" data-rm-shortcode-id="378380d273bf4a1c9606370acea15e58"> <div id="botr_8PLWDgcM_FvQKszTI_div" class="jwplayer-media" data-jwplayer-video-src="https://content.jwplatform.com/players/8PLWDgcM-FvQKszTI.js"> <img src="https://cdn.jwplayer.com/thumbs/8PLWDgcM-1920.jpg" class="jwplayer-media-preview" /> </div> <script src="https://content.jwplatform.com/players/8PLWDgcM-FvQKszTI.js"></script> </div> <p>Previous studies on this topic point in the same direction. Those studies and the models they inspired suggested that increased temperatures could increase soil-based carbon emissions, but they all underestimated how much carbon would be involved.</p><p>A 2016 study focusing on temperate soils also concluded that increasing soil temperatures would increase their carbon <a href="https://www.nature.com/articles/nature20150" target="_blank">emissions</a>. They predicted that, if left unchecked, these emissions would equal the amount produced by a country similar to the United States over the next few <a href="https://www.ucsusa.org/resources/each-countrys-share-co2-emissions" target="_blank" rel="noopener noreferrer dofollow">decades</a>. Another experiment in Colorado found similar <a href="https://science.sciencemag.org/content/355/6332/1420" target="_blank" rel="noopener noreferrer dofollow">results</a>. Both of these studies found lower increases in carbon emissions by percentage than the study on Barro Colorado. </p><p>However, these studies did not take place in the tropics, and the differences in the soils between temperate and tropical zones could explain the differences between the studies. Moreover, the dirt on Barro Colorado Island differs from the dirt in the Amazon and may be more inclined to produce more emissions when the heat is turned up. The same can be said of tropical soils <a href="https://www.nytimes.com/2020/08/12/climate/tropical-soils-climate-change.html?searchResultPosition=3&utm_campaign=Hot%20News&utm_medium=email&_hsmi=93170710&_hsenc=p2ANqtz-8McWKRhE8U9ChcWW2qkqNyp2Qndzr1aJmGlrMUwK_h1bM8RDQukWcM8r2OcBKW2Y0bWlRr9o4WUixKDzIo4HzKkVv19g&utm_content=93170710&utm_source=hs_email" target="_blank" rel="noopener noreferrer dofollow">elsewhere</a>. </p><p>Another <a href="https://www.forestwarming.org/" target="_blank" rel="noopener noreferrer dofollow">experiment</a>, very similar to the one in Panama, is currently underway in Puerto Rico. However, this experiment is taking the extra step of also heating the plants near the heated soil to see what the effect of warmer temperatures is on their ability to absorb carbon.</p><p>The current study also did not heat the soil past the one-meter mark and cannot provide us with predictions of what more comprehensive heating of the soil would do to emissions. It was also comparatively short, and the effect may be reduced in the long run as the nutrients in the soil are depleted by the increased activity of the microbes, which are using the carbon and other resources to <a href="https://www.nature.com/articles/d41586-020-02266-9" target="_blank" rel="noopener noreferrer dofollow">reproduce</a>. </p><p>The team behind the most recent study will continue their experiment to try and understand how tropical ecosystems respond to increased <a href="https://www.earth.com/news/billions-of-tons-of-co2-could-be-released-from-tropical-soils/" target="_blank" rel="noopener noreferrer dofollow">temperatures</a> over more extended periods of time. </p><p>As we increase our understanding of the planet and its various environmental systems, the potential consequences of climate change become clearer and more horrifying. This new study supports previous findings that suggest disrupting soils can increase carbon emissions. While it may be too soon to tell if the eye-popping increases found by this study are typical or an outlier, they do re-enforce the notion that a breakdown in the systems that keep the climate stable is possible if nothing changes. </p>
A study published Friday tested how well 14 commonly available face masks blocked the emission of respiratory droplets as people were speaking.
- The study tested the efficacy of popular types of face masks, including N95 respirators, bandanas, cotton-polypropylene masks, gaiters and others.
- The results showed that N95 respirators were most effective, while wearing a neck fleece (aka gaiter) actually produced more respiratory droplets than wearing no mask at all.
- Certain types of homemade masks seem to be effective at blocking the spread of COVID-19.
Fischer et al.<p>A smartphone camera recorded video of the participants, and a computer algorithm counted the number of droplets they emitted. To establish a control trial, the participants spoke into the box both with and without a mask. And to make sure that the droplets weren't in fact dust from the masks, the team conducted more tests by "repeatedly puffing air from a bulb through the masks."</p>
Fischer et al.<p>The results, published Friday in <a href="https://advances.sciencemag.org/content/early/2020/08/07/sciadv.abd3083" target="_blank">Science Advances</a>, showed that some masks are pretty much useless. In particular, neck fleeces (also called gaiters) actually produced more respiratory droplets compared to the control trial — likely because the fabric breaks down big droplets into smaller ones.</p><p>The top three most effective masks were N95 respirators, surgical masks and polypropylene-cotton masks. Bandanas performed the worst, but were slightly better than wearing no mask at all.</p>
Fischer et al.<p>Research on mask efficacy is still emerging. But the new results seem to generally align with <a href="https://newsroom.wakehealth.edu/News-Releases/2020/04/Testing-Shows-Type-of-Cloth-Used-in-Homemade-Masks-Makes-a-Difference" target="_blank" rel="noopener noreferrer dofollow">prior tests</a>. For example, a study from June published in <a href="https://aip.scitation.org/doi/10.1063/5.0016018" target="_blank" rel="noopener noreferrer dofollow">Physics of Fluid</a> found that bandanas (followed by folded handkerchiefs) were least effective at blocking respiratory droplets. That same study also found, as <a href="https://newsroom.wakehealth.edu/News-Releases/2020/04/Testing-Shows-Type-of-Cloth-Used-in-Homemade-Masks-Makes-a-Difference" target="_blank" rel="noopener noreferrer dofollow">others have</a>, that masks made from multiple layers of quilter's fabric were especially effective at blocking droplets.</p><p>The researchers hope other institutions will conduct similar experiments so the public can see how well different masks can block the spread of COVID-19.</p><p style="margin-left: 20px;">"This is a very powerful visual tool to raise awareness that a very simple masks, like these homemade cotton masks, do really well to stop the majority of these respiratory droplets," Fischer told CNN. "Companies and manufacturers can set this up and test their mask designs before producing them, which would also be very useful."</p>
SMARTER FASTER trademarks owned by The Big Think, Inc. All rights reserved.