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The worst time of middle age? When you’re 47.
Researcher discovers a universal slump in life satisfaction.

- In 132 countries, a clear U shape is seen in happiness in the late 40s.
- The study controls for influencing factors in arriving at its conclusions.
- Three possible reasons for a post-middle-age return to happiness are suggested.
It's a good-news, bad-news thing. The bad new first: Statistically speaking, according to a a new study and companion paper, if your 47th birthday was 73 days ago, this is the worst time of your life. (That means you're 47.2 years old in case you're too depressed to do the math.) The good news: Things can only get better. The even better news: If you're doing well these days, lucky you, though if you live in the developing world, you've got another year until things bottom out.
The research comes from Dartmouth's David Blanchflower in two new reports published by the National Bureau of Economic Research. It's hoped the conclusions drawn in the studies provide additional insight for those providing mental-health care, or those experiencing difficulties themselves. Middle age is a rough passage for many people. Blanchflower writes, "It seems that the middle aged have had particular difficulties in adapting in the years of slow growth since the Great Recession of 2008 and 2009. The interaction between a nadir for happiness among the middle-aged along with a major downturn has had major social, political and health consequences that have reverberated around the world."
A world full of middle-age blah
Image source: fizkes/Shutterstock
For "Is Happiness U-Shaped Everywhere? Age And Subjective Well-Being In 132 Countries," Blanchflower analyzed data from ninety-five developing countries and thirty-seven advanced countries to conclude there's a universal "happiness curve" in life, a U shape that reaches its lowest point in middle age. It was so common in the data, Blanchflower writes, that "It was really hard not to find the U-shape." Surprisingly, "the curve's trajectory holds true in countries where the median wage is high and where it is not and where people tend to live longer and where they don't."
Paradoxically, those living in less developed regions, and who thus have a shorter average lifespan, get an additional year before hitting rock bottom, though that bottom may be worse. In the supplementary study, "Unhappiness and Age," Blanchflower writes, "The resiliency of communities left behind by globalization was diminished by the Great Recession which made it especially hard for the vulnerable undergoing a midlife crisis with few resources to withstand the shock."
One of the questions Branchflower was interested in investigating is whether or not "unhappiness is simply the inverse of happiness." Supporting the notion is that the data revealed an inverted U unhappiness curve. Blanchflower writes:
"The happiness curve was found using a variety of measures of well-being but was especially [based on] happiness and life satisfaction. But a group of other measures were used including views on politics and the economy as well as with an individual's life experience including their family [life], their living standards, the local area where they lived and [so] on."
Defending his methods
Despair among White U.S. residents during two overlapping periods, with and without controls
Image source: National Bureau Of Economic Research, ©2020 David G. Blanchflower
Blanchflower's approach is not without controversy.
In response to earlier research, he writes, one critic protested "that the appearance of this U-shaped curve of well-being is the result of the use of inappropriate and questionable control variables," especially marital status. Blanchflower says in rebuttal that the U shape appears even without such controls, as shown above.
The dispute appears to hinge on the conclusions one wants to draw from collected data. As an example, Blanchflower says that when pronouncing a simple statistical truth — citing "smokers die at rate Z" — not factoring in other controls makes sense. However, this wouldn't be the case when attempting to identify implications within the data, one of the goals of his research. Using aging's effect on happiness and its role in relationships as an example, he writes, "it would likely be an error to use an equation without controls to tell the public what impact aging has on happiness without separating out the effects of other variables such as, say, education, marriage or unemployment."
What's going on
Image source: Mathew Bennett/unsplash
Blanchflower suggests three possible reasons for people's mid-life crises and their ability to bounce back from them:
- Individuals learn to "adapt to their strengths and weaknesses, and in mid-life quell their infeasible aspirations."
- One becomes grateful in time for the good things in their lives. Blanchflower cites his personal experience: "I have seen school-friends die and come eventually to value my blessings during my remaining years."
- It could be that cheerful people live longer, and that the U-shape simply reflects this.
- Healthy sex life can reduce depression and anxiety symptoms - Big ... ›
- The 'Great Midlife Edit': How to master your middle years - Big Think ›
Dogs digest human food better and poop less
A new study finds that dogs fed fresh human-grade food don't need to eat—or do their business—as much.
- Most dogs eat a diet that's primarily kibble.
- When fed a fresh-food diet, however, they don't need to consume as much.
- Dogs on fresh-food diets have healthier gut biomes.
Four diets were tested
<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNTU5ODI1MS9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTY1NjY0NjIxMn0._w0k-qFOC86AqmtPHJBK_i-9F5oVyVYsYtUrdvfUxWQ/img.jpg?width=980" id="1b1e4" class="rm-shortcode" data-rm-shortcode-id="87937436a81c700a8ab3b1d763354843" data-rm-shortcode-name="rebelmouse-image" data-width="1440" data-height="960" />Credit: AntonioDiaz/Adobe Stock
<p>The researchers tested refrigerated and fresh human-grade foods against kibble, the food most dogs live on. The <a href="https://frontierpets.com.au/blogs/news/how-kibble-or-dry-dog-food-is-made" target="_blank">ingredients</a> of kibble are mashed into a dough and then extruded, forced through a die of some kind into the desired shape — think a <a href="https://en.wikipedia.org/wiki/Food_extrusion" target="_blank">pasta maker</a>. The resulting pellets are sprayed with additional flavor and color.</p><p>For four weeks, researchers fed 12 beagles one of four diets:</p><ol><li>a extruded diet — Blue Buffalo Chicken and Brown Rice Recipe</li><li>a fresh refrigerated diet — Freshpet Roasted Meals Tender Chicken Recipe</li><li>a fresh diet — JustFoodforDogs Beef & Russet Potato Recipe</li><li>another fresh diet — JustFoodforDogs Chicken & White Rice Recipe.</li></ol><p>The two fresh diets contained minimally processed beef, chicken, broccoli, rice, carrots, and various food chunks in a canine casserole of sorts. </p><p>(One can't help but think how hard it would be to get finicky cats to test new diets. As if.)</p><p>Senior author <a href="https://ansc.illinois.edu/directory/ksswanso" target="_blank" rel="noopener noreferrer">Kelly S. Swanson</a> of U of I's Department of Animal Sciences and the Division of Nutritional Sciences, was a bit surprised at how much better dogs did on people food than even refrigerated dog chow. "Based on past research we've conducted I'm not surprised with the results when feeding human-grade compared to an extruded dry diet," he <a href="https://aces.illinois.edu/news/feed-fido-fresh-human-grade-dog-food-scoop-less-poop" target="_blank">says</a>, adding, "However, I did not expect to see how well the human-grade fresh food performed, even compared to a fresh commercial processed brand."</p>Tracking the effect of each diet
<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNTU5ODI1OC9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTY3NjY1NTgyOX0.AdyMb8OEcjCD6iWYnXjToDmcnjfTSn-0-dfG96SIpUA/img.jpg?width=980" id="da892" class="rm-shortcode" data-rm-shortcode-id="880d952420679aeccd1eaf32b5339810" data-rm-shortcode-name="rebelmouse-image" data-width="1440" data-height="960" />Credit: Patryk Kosmider/Adobe Stock
<p>The researchers tracked the dogs' weights and analyzed the microbiota in their fecal matter.</p><p>It turned out that the dogs on kibble had to eat more to maintain their body weight. This resulted in their producing 1.5 to 2.9 times the amount of poop produced by dogs on the fresh diets.</p><p>Says Swanson, "This is consistent with a 2019 National Institute of Health study in humans that found people eating a fresh whole food diet consumed on average 500 less calories per day, and reported being more satisfied, than people eating a more processed diet."</p><p>Maybe even more interesting was the effect of fresh food on the gut biome. Though there remains much we don't yet know about microbiota, it was nonetheless the case that the microbial communities found in fresh-food poo was different.</p><p>"Because a healthy gut means a healthy mutt," says Swanson, "fecal microbial and metabolite profiles are important readouts of diet assessment. As we have shown in <a href="https://academic.oup.com/jas/article/92/9/3781/4702209#110855647" target="_blank">previous studies</a>, the fecal microbial communities of healthy dogs fed fresh diets were different than those fed kibble. These unique microbial profiles were likely due to differences in diet processing, ingredient source, and the concentration and type of dietary fibers, proteins, and fats that are known to influence what is digested by the dog and what reaches the colon for fermentation."</p>How did kibble take over canine diets?
<p>Historically, dogs ate scraps left over by humans. It has only been <a href="https://www.thefarmersdog.com/digest/the-history-of-commercial-pet-food-a-great-american-marketing-story/" target="_blank">since 1870</a>, with the arrival of the luxe Spratt's Meat Fibrine Dog Cakes—made from "the dried unsalted gelatinous parts of Prairie Beef", mmm—that commercial dog food began to take hold. Dog bone-shaped biscuits first appeared in 1907. Ken-L Ration dates from 1922. Kibble was first extruded in 1956. Pet food had become a great way to turn <a href="https://www.dogfoodadvisor.com/choosing-dog-food/animal-by-products/" target="_blank">human-food waste</a> into profit.</p><p>Commercial dog food became the norm for most household canines only after a massive marketing campaign led by a group of dog-food industry lobbyists called the Pet Food Institute in 1964. Over time, for most households, dog food was what dogs ate — what else? Human food? These days more than half of U.S. dogs are <a href="https://www.nytimes.com/2014/08/03/magazine/who-made-that-dog-biscuit.html" target="_blank">overweight or obese</a>, and certainly their diet is a factor.<span></span></p><p>We're not so special among animals after all. If something's healthy for us to eat—we're <em>not</em> looking at you, chocolate—maybe we should remember to share with our canine compatriots. Not from the table, though.</p>New study suggests placebo might be as powerful as psychedelics
New study suggests the placebo effect can be as powerful as microdosing LSD.
- New research from Imperial College London investigated the psychological effects of microdosing LSD in 191 volunteers.
- While microdosers experienced beneficial mental health effects, the placebo group performed statistically similar to those who took LSD.
- Researchers believe the expectation of a trip could produce some of the same sensations as actually ingesting psychedelics.
Psychedelics: The scientific renaissance of mind-altering drugs
<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="92360c805fe66c11de38a75b0967f417"><iframe type="lazy-iframe" data-runner-src="https://www.youtube.com/embed/5T0LmbWROKY?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span><p>For the study published in eLife, the team recruited 191 citizen cosmonauts to microdose either LSD or a placebo over the course of several weeks and note the psychological effects. Volunteers were already microdosing LSD, so there was no true control. Each volunteer was given instructions on creating their own low-dose gel capsules, some containing LSD, others not. Then they mixed the capsules in envelopes so they didn't know if they were taking the real thing or not.</p><p>The trial design was ingenious: each capsule featured a QR code that was scanned after the addition of ingredients but before they were placed in the envelope so that researchers knew what they were ingesting.</p><p>The problem: volunteers sourced their own LSD. Lack of quality control could have had a profound effect on the results. </p><p>The results: LSD microdosers reported feeling more mindful, satisfied with life, and better overall; they also noticed a reduction in feelings of paranoia. </p><p>The catch: the control group felt the same thing, with no statistical difference between the groups. </p><p>Lead author Balázs Szigeti comments on the findings: "This suggests that the improvements may not be due to the pharmacological action of the drug but can instead be explained by the placebo effect." </p>Credit: Alexander / Adobe Stock
<p>Psychedelics are notoriously difficult to control for given the intensity of the experience. Yet there is precedent for the above findings. A <a href="https://link.springer.com/article/10.1007/s00213-020-05464-5" target="_blank">2019 study</a> found that 61 percent of volunteers that took a placebo instead of psilocybin felt some psychedelic effects, with a few volunteers experiencing full-on trips.</p><p style="margin-left: 20px;">"Several stated that they saw the paintings on the walls 'move' or 'reshape' themselves, others felt 'heavy. . . as if gravity [had] a stronger hold', and one had a 'come down' before another 'wave' hit her."</p><p>The Imperial team believes the expectation of a trip might have been enough to produce similar results. Senior author David Erritzoe is excited for future studies on the topic, believing they tapped into a new wave of citizen science that could push forward our knowledge of psychedelic substances.</p><p style="margin-left: 20px;">"Accounting for the placebo effect is important when assessing trends such as the use of cannabidiol oils, fad diets or supplements where social pressure or users' expectations can lead to a strong placebo response. Self-blinding citizen science initiatives could be used as an inexpensive, initial screening tool before launching expensive clinical studies."</p><p>As investments into the psychedelics market explode, with one company <a href="https://www.bloomberg.com/news/articles/2021-03-03/thiel-backed-magic-mushroom-firm-atai-hits-2-billion-valuation" target="_blank">reaching a $2 billion valuation</a>, a recurring irony appears in the long arc of psychedelics and research: the power of our minds might be enough to feel greater life satisfaction and a deeper sense of mindfulness. If that's possible with a placebo, we have to question why the rush to create more pharmacology is necessary. </p><p>This is, mind you, a separate conversation over the role of psychedelics and rituals for group bonding. The function of group cohesion around consciousness-altering substances will continue to play an important role in many communities. </p><p>Of course, we should continue to explore the efficacy of psychedelics on anxiety, depression, suicidal ideation, PTSD, and addiction. <a href="https://bigthink.com/surprising-science/antidepressant-effects" target="_self">Pharmacological dependence</a> is a stain on the psychiatry industry. Whether or not psychedelics can be prescribed for daily use remains to be seen, but we know a moneyed interest is expecting a return on investment—the above company, ATAI Life Sciences, raised $157 million in its Series D round. </p><p>When it comes to wellbeing, some things money just can't buy. How we navigate the tricky terrain of mainstreaming psychedelics remains to be seen. </p><p>--</p><p><em>Stay in touch with Derek on <a href="http://www.twitter.com/derekberes" target="_blank">Twitter</a> and <a href="https://www.facebook.com/DerekBeresdotcom" target="_blank" rel="noopener noreferrer">Facebook</a>. His most recent book is</em> "<em><a href="https://www.amazon.com/gp/product/B08KRVMP2M?pf_rd_r=MDJW43337675SZ0X00FH&pf_rd_p=edaba0ee-c2fe-4124-9f5d-b31d6b1bfbee" target="_blank" rel="noopener noreferrer">Hero's Dose: The Case For Psychedelics in Ritual and Therapy</a>."</em></p>Your genetics influence how resilient you are to the cold
What makes some people more likely to shiver than others?
Some people just aren't bothered by the cold, no matter how low the temperature dips. And the reason for this may be in a person's genes.
Harvard study finds perfect blend of fruits and vegetables to lower risk of death
Eating veggies is good for you. Now we can stop debating how much we should eat.
