Which Genes Cause Disease?

New genomic analyses suggest that the most common genetic variants in the human genome aren't the ones most likely causing disease, genetic experts at Duke University Medical Center report.

Dr. David Goldstein, director of the Duke Center for Human Genome Variation, said: "'The more common a variant is, the less likely it is to be found in a functional region of the genome. Scientists have reported this observation before, but this study is the most comprehensive effort to date using annotations of the functional regions of the human genome and fully sequenced genomes.' ... He also said he was surprised by the notable consistency of the finding. 'It's not just that the most rare variants are different from the most common, it's that at every increase in frequency, a variant is less and less likely to be found in a functional region of the DNA,' Goldstein said."

LinkedIn meets Tinder in this mindful networking app

Swipe right to make the connections that could change your career.

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Swipe right. Match. Meet over coffee or set up a call.

No, we aren't talking about Tinder. Introducing Shapr, a free app that helps people with synergistic professional goals and skill sets easily meet and collaborate.

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4 reasons Martin Luther King, Jr. fought for universal basic income

In his final years, Martin Luther King, Jr. become increasingly focused on the problem of poverty in America.

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Politics & Current Affairs
  • Despite being widely known for his leadership role in the American civil rights movement, Martin Luther King, Jr. also played a central role in organizing the Poor People's Campaign of 1968.
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  • Today, the idea of a universal basic income is increasingly popular, and King's arguments in support of the policy still make a good case some 50 years later.
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Dead – yes, dead – tardigrade found beneath Antarctica

A completely unexpected discovery beneath the ice.

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Surprising Science
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  • The creatures' origin is unknown, and further study is ongoing.
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10 reasons to be optimistic in 2019


Rwanda is pioneering the regulation and use of drones - such as delivering blood

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Politics & Current Affairs

Even the optimists among us would have to admit 2018 was a challenging year. The fractured world that became the focus of our 2018 Annual Meeting a year ago came under further pressure from populist rhetoric and rising nationalist agendas. At the same time, the urgent need for coordinated global action in areas such as climate change, inequality and the impact of automation on jobs became more intense.

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