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Mouse ADHD Clue
A new study using mice has revealed that the root of psychiatric disorder attention deficit/hyperactivity disorder (ADHD) might be found in an overactive protein.
A new study using mice has revealed that the root of psychiatric disorder attention deficit/hyperactivity disorder (ADHD) might be found in an overactive protein which is responsible for regulating the dopaminergic pathways. Although ADHD is typically seen as a condition affecting teenagers, it also affects around 5% of adults, and this breakthrough could help scientists to progress with finding it’s as yet unknown cause. The discovery has been added to a growing body of evidence which suggests that dopamine, a neurotransmitter involved in the brain’s reward-motivation system, could trigger the disorder. "The genetically modified mice that we generated present interesting features such as hyperactivity and altered nesting capacities that might be related to attention deficit, and possibly altered impulsivity," Marc Flajolet, a senior research associate at the Rockefeller University which engaged in the research. "We believe that over expression of CK1δ [an enzyme called casein kinase] induces some developmental steps that resemble what might be happening in ADHD patients and therefore we propose that the CK1δ-overexpressing mice are a model for this disorder," says Flajolet. "It will be interesting to investigate if CK1 could be the origin of developmental defects in humans that lead to ADHD."
Join the legend of non-fiction in conversation with best-selling author and poker pro Maria Konnikova.
China moves to Russia and India takes over Canada. The Swiss get Bangladesh, the Bangladeshi India. And the U.S.? It stays where it is.
What if the world were rearranged so that the inhabitants of the country with the largest population would move to the country with the largest area? And the second-largest population would migrate to the second-largest country, and so on?
The space tourism company Virgin Galactic teams up with Rolls Royce to create a new Mach 3 supersonic aircraft.
- Richard Branson's Virgin Galactic announces a partnership with Rolls Royce.
- The space tourism company will create a new supersonic jet for super-fast travel on Earth.
- The aircraft will travel at Mach 3 – three times the speed of sound.
Credit: Virgin Galactic
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Andy Samberg and Cristin Milioti get stuck in an infinite wedding time loop.
- Two wedding guests discover they're trapped in an infinite time loop, waking up in Palm Springs over and over and over.
- As the reality of their situation sets in, Nyles and Sarah decide to enjoy the repetitive awakenings.
- The film is perfectly timed for a world sheltering at home during a pandemic.