Mouse ADHD Clue
A new study using mice has revealed that the root of psychiatric disorder attention deficit/hyperactivity disorder (ADHD) might be found in an overactive protein.
A new study using mice has revealed that the root of psychiatric disorder attention deficit/hyperactivity disorder (ADHD) might be found in an overactive protein which is responsible for regulating the dopaminergic pathways. Although ADHD is typically seen as a condition affecting teenagers, it also affects around 5% of adults, and this breakthrough could help scientists to progress with finding it’s as yet unknown cause. The discovery has been added to a growing body of evidence which suggests that dopamine, a neurotransmitter involved in the brain’s reward-motivation system, could trigger the disorder. "The genetically modified mice that we generated present interesting features such as hyperactivity and altered nesting capacities that might be related to attention deficit, and possibly altered impulsivity," Marc Flajolet, a senior research associate at the Rockefeller University which engaged in the research. "We believe that over expression of CK1δ [an enzyme called casein kinase] induces some developmental steps that resemble what might be happening in ADHD patients and therefore we propose that the CK1δ-overexpressing mice are a model for this disorder," says Flajolet. "It will be interesting to investigate if CK1 could be the origin of developmental defects in humans that lead to ADHD."
Swipe right to make the connections that could change your career.
Swipe right. Match. Meet over coffee or set up a call.
No, we aren't talking about Tinder. Introducing Shapr, a free app that helps people with synergistic professional goals and skill sets easily meet and collaborate.
The Oxfam report prompted Anand Giridharadas to tweet: "Don't be Pinkered into everything's-getting-better complacency."
- A new report by Oxfam argues that wealth inequality is causing poverty and misery around the world.
- In the last year, the world's billionaires saw their wealth increase by 12%, while the poorest 3.8 billion people on the planet lost 11% of their wealth.
- The report prompted Anand Giridharadas to tweet: "Don't be Pinkered into everything's-getting-better complacency." We explain what Steven Pinker's got to do with it.
Evolution doesn't clean up after itself very well.
- An evolutionary biologist got people swapping ideas about our lingering vestigia.
- Basically, this is the stuff that served some evolutionary purpose at some point, but now is kind of, well, extra.
- Here are the six traits that inaugurated the fun.
- Facebook and Google began as companies with supposedly noble purposes.
- Creating a more connected world and indexing the world's information: what could be better than that?
- But pressure to return value to shareholders came at the expense of their own users.
SMARTER FASTER trademarks owned by The Big Think, Inc. All rights reserved.