Mouse ADHD Clue
A new study using mice has revealed that the root of psychiatric disorder attention deficit/hyperactivity disorder (ADHD) might be found in an overactive protein.
A new study using mice has revealed that the root of psychiatric disorder attention deficit/hyperactivity disorder (ADHD) might be found in an overactive protein which is responsible for regulating the dopaminergic pathways. Although ADHD is typically seen as a condition affecting teenagers, it also affects around 5% of adults, and this breakthrough could help scientists to progress with finding it’s as yet unknown cause. The discovery has been added to a growing body of evidence which suggests that dopamine, a neurotransmitter involved in the brain’s reward-motivation system, could trigger the disorder. "The genetically modified mice that we generated present interesting features such as hyperactivity and altered nesting capacities that might be related to attention deficit, and possibly altered impulsivity," Marc Flajolet, a senior research associate at the Rockefeller University which engaged in the research. "We believe that over expression of CK1δ [an enzyme called casein kinase] induces some developmental steps that resemble what might be happening in ADHD patients and therefore we propose that the CK1δ-overexpressing mice are a model for this disorder," says Flajolet. "It will be interesting to investigate if CK1 could be the origin of developmental defects in humans that lead to ADHD."
It's the first time the association hasn't hired a comedian in 16 years.
- The 2018 WHCA ended in controversy after comedian Michelle Wolf made jokes some considered to be offensive.
- The WHCA apologized for Wolf's jokes, though some journalists and many comedians backed the comedian and decried arguments in favor of limiting the types of speech permitted at the event.
- Ron Chernow, who penned a bestselling biography of Alexander Hamilton, will speak at next year's dinner.
Progressive America would be half as big, but twice as populated as its conservative twin.
- America's two political tribes have consolidated into 'red' and 'blue' nations, with seemingly irreconcilable differences.
- Perhaps the best way to stop the infighting is to go for a divorce and give the two nations a country each
- Based on the UN's partition plan for Israel/Palestine, this proposal provides territorial contiguity and sea access to both 'red' and 'blue' America
A study on flies may hold the key to future addiction treatments.
- A new study suggests that drinking alcohol can affect how memories are stored away as good or bad.
- This may have drastic implications for how addiction is caused and how people recall intoxication.
- The findings may one day lead to a new form of treatment for those suffering from addiction.
SMARTER FASTER trademarks owned by The Big Think, Inc. All rights reserved.