Lack of Single Protein Causes Persistent Viral Infection
According to studies, the absence of a very important protein in the body leads to viral infections taking permanent residency in a person's immune system.
Article written by guest writer Rin Mitchell
What’s the Latest Development?
Researchers from the Scripps Research Institute have discovered a protein believed to aid in the passing of viral infections. Based on a study that examined mice affected with lymphocytic choriomeningitis virus (LCMV), the mice that lacked the TLR7 protein were unable to clear the infection—whereas the mice with the protein could clear the virus in two to three months. When an infection like HIV, Influenza, LCMV, Hepatitis enters the body, the first line of defense are Toll-Like Receptors (TLR). These receptors alert the immune system when something that doesn’t belong has arrived. The TLR7 is the most important protein in the line of defense to shield any viruses evading the immune system. According to the studies on mice, when the TLR7 receptor was absent the immune system became compromised. The immune memory cells could not clear the infection alone in the TLR7-deficient mice.
What’s the Big Idea?
Researcher's studies on mice reveal that the protein TLR7 assists in the clearing of viral infections. Scientists used LCMV in mice that were missing the protein to better understand the function of TLR7. They were unable to pass infections, and basic immune fighting cells were not enough to do the job. This discovery will help scientists seek ways to treat persistent human infections.
The new offices will be built in New York's Long Island City and Viriginia's Arlington.
- Amazon will receive more than $2 billion in incentives from the two states.
- The company plans to create a total of 50,000 jobs at an average wage of $150,000.
- The announcement has caused controversy, raising concerns about rising rent prices and potentially lost resources in communities surrounding the upcoming developments.
The results come from a 15-year study that used ultrasound scans to track blood vessels in middle-aged adults starting in 2002.
- The study measured the stiffness of blood vessels in middle-aged patients over time.
- Stiff blood vessels can lead to the destruction of delicate blood vessels in the brain, which can contribute to cognitive decline.
- The scans could someday become a widely used tool to identify people at high risk of developing dementia and Alzheimer's.
Dozens of mummified cats were dug up this week. This isn't as shocking as you might think.
- Archaeologists in Egypt have found dozens of mummified cats in the tomb of a royal offical.
- The cats will join the ranks of hundreds of thousands of previously discovered ancient kitties.
- While the cats are nothing special, the tomb also held well preserved beetles.
SMARTER FASTER trademarks owned by The Big Think, Inc. All rights reserved.