Gene Therapy to Treat Depression
"Researchers find they can alleviate depression in mice by boosting a protein in one part of the brain." Technology Review on how gene therapy could be used in humans.
"For decades, medications for depression have acted pretty much the same way—by manipulating levels of serotonin and other chemical messengers in the brain. New drugs have offered only modest changes from the old ones. Now a team of researchers, led by Michael Kaplitt, an associate professor at Weill Cornell Medical College, has proposed a different way to attack depression: by using gene therapy to boost levels of a protein called p11 in an area of the brain called the nucleus accumbens. 'We do believe that the deficiency of this gene in this area of the brain may be one of the underlying root causes of depression, and that addressing that could help improve symptoms,' says Kaplitt."
There's a high social cost that comes with lighting up.
While short-term results are positive, there is mounting evidence against staying in ketosis for too long.
- Recent studies showed volunteers lost equal or more weight on high-carb, calorie-restricted diets than low-carb, calorie restricted diets.
- There might be positive benefits to short-term usage of a ketogenic diet.
- One dietician warns that the ketogenic diet could put diabetics at risk for diabetic ketoacidosis.
Research shows that the way math is taught in schools and how its conceptualized as a subject is severely impairing American student's ability to learn and understand the material.
- Americans continually score either in the mid- or bottom-tier when it comes to math and science compared to their international peers.
- Students have a fundamental misunderstanding of what math is and what it can do. By viewing it as a language, students and teachers can begin to conceptualize it in easier and more practical ways.
- A lot of mistakes come from worrying too much about rote memorization and speedy problem-solving and from students missing large gaps in a subject that is reliant on learning concepts sequentially.
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