A genetic propensity may be responsible for some alcohol dependence, according to new research which links alcoholism to a cluster of genes on chromosome 11.
A genetic propensity may be responsible for some alcohol dependence, according to new research which links alcoholism to a cluster of genes on chromosome 11. "Previous studies have looked at one or a few genes at a time, choosing the genes based upon hypotheses about possible mechanisms underlying differences in risk for alcoholism," Howard J. Edenberg, Distinguished Professor at the Indiana University School of Medicine and corresponding author for the study, told Science Daily. "We chose to examine the entire genome, all the genes at once, as an unbiased approach that has the potential of uncovering previously unsuspected genes." "Geneticists use many strategies to find gene locations, and genes," said David Goldman, section chief of Human Neurogenetics at the National Institute on Alcohol Abuse and Alcoholism. "Here, approximately one million genetic polymorphisms or variants were analyzed in a population framework of approximately 1400 unrelated individuals. Then the most significant variants were followed up in several ways: 'Were they also associated in families?' 'Were they expressed in brain?' 'Were their patterns of expression altered by alcohol?' Several were. [These results] illustrate the power of new genetic technology to perform a genome-wide sieving, something that was impossible only a few years ago."
Malcolm Gladwell teaches "Get over yourself and get to work" for Big Think Edge.
- Learn to recognize failure and know the big difference between panicking and choking.
- At Big Think Edge, Malcolm Gladwell teaches how to check your inner critic and get clear on what failure is.
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Neuroscience research suggests it might be time to rethink our ideas about when exactly a child becomes an adult.
- Research suggests that most human brains take about 25 years to develop, though these rates can vary among men and women, and among individuals.
- Although the human brain matures in size during adolescence, important developments within the prefrontal cortex and other regions still take pace well into one's 20s.
- The findings raise complex ethical questions about the way our criminal justice systems punishes criminals in their late teens and early 20s.
Three scientists publish a paper proving that Mercury, not Venus, is the closest planet to Earth.
- Earth is the third planet from the Sun, so our closest neighbor must be planet two or four, right?
- Wrong! Neither Venus nor Mars is the right answer.
- Three scientists ran the numbers. In this YouTube video, one of them explains why our nearest neighbor is... Mercury!
A new method of growing mini-brains produces some startling results.
- Researchers find a new and inexpensive way to keep organoids growing for a year.
- Axons from the study's organoids attached themselves to embryonic mouse spinal cord cells.
- The mini-brains took control of muscles connected to the spinal cords.
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