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Genius Series: The defiant life of Marie Curie
Big Think has launched a line of apparel and goods that celebrate the life and work of four geniuses.
- Big Think has just launched its Genius Series of tees, sweatshirts, posters and more!
- We're paying tribute to the first female Nobel Prize winner, Marie Curie.
- Select Rush or Super Rush Delivery to get your order before Christmas Day!
Life is not easy for any of us. But what of that? We must have perseverance and above all confidence in ourselves. We must believe that we are gifted for something, and that this thing, at whatever cost, must be attained.
– Marie Curie
Marie Curie was a trailblazing physicist working in the 19th and 20th centuries, and remains the only person to this day to have won a Nobel Prize in two different sciences: physics and chemistry.
Curie was born in Poland, and although she was a brilliant student she was barred from higher education because she was a woman. Determined to study, she enrolled in a secret institution known as the Flying University, which defied government control of education, then moved to Paris to study physics and mathematics at the Sorbonne.
In Paris, she met physicist Pierre Curie, who became her partner in life and in the lab—and who defiantly fought for her recognition when the Nobel academy did not include her alongside him in the Nobel Prize nomination.
Curie changed the way we understood the structure of atoms, invented a mobile x-ray unit (and trained 150 women to operate them on the WWI battlefields), discovered radioactivity (and coined the term), and discovered two elements: polonium, named after her native Poland, and radium, the Latin word for 'ray'.
Our Marie Curie design pays tribute to this remarkable scientist's life and work. Wear it proudly, and—as Curie says above—have confidence that your gifts can be put to powerful use.
Select Rush or Super Rush Delivery to get your order before Christmas Day!
A new study explores how the brain encodes different scents — a topic which scientists know relatively little about, compared to our other senses.
- Unlike sight and hearing, our sense of smell remains poorly understood.
- In a new study, scientists used machine learning to categorize thousands of different odors, based on chemical properties.
- By exposing mice to odors and measuring their neural activity, the scientists found that the brain more closely groups together odors that are chemically similar.
Illustration of multiphoton microscopy
Pashkovski et al.<p style="margin-left: 20px;"><br></p><p>To investigate, the researchers created a database of thousands of odorous chemical structures, and they used machine learning to categorize them by features such as number of atoms, molecular weight and electrochemical properties. These odors were separated into three categories: high diversity, intermediate diversity and low diversity.</p><p>Then the researchers exposed different odors to mice, and used multiphoton microscopy to record neural activity in the piriform cortex and olfactory bulb. The results showed that when odors are chemically similar, so too is neural activity. In other words, the cortex emphasizes relationships between chemically similar odors, and it creates groupings for similar odors, which helps us distinguish between objects in the world. </p>
Smell and neuroplasticity<p>The results also suggest that perception of smell is flexible. For example, the team repeatedly exposed mice to a combination of two chemically dissimilar odors. Over time, images showed that the neural patterns produced by the pair of odors become more strongly correlated.</p><p style="margin-left: 20px;">"We presented two odors as if they're from the same source and observed that the brain can rearrange itself to reflect passive olfactory experiences," Datta said. "The plasticity of the cortex may help explain why smell is on one hand invariant between individuals, and yet customizable depending on our unique experiences."</p>
Pixabay<p>The study provides some of the first information on how the olfactory cortex maps different odors. And the results also suggest that, by better understanding the chemical structure of different odors and how that mapping process works, scientists may someday be able to better control our sense of smell.</p><p style="margin-left: 20px;">"We don't fully understand how chemistries translate to perception yet," Datta said. "There's no computer algorithm or machine that will take a chemical structure and tell us what that chemical will smell like. To actually build that machine and to be able to someday create a controllable, virtual olfactory world for a person, we need to understand how the brain encodes information about smells. We hope our findings are a step down that path."</p>
Frequent shopping for single items adds to our carbon footprint
- A new study shows e-commerce sites leave larger greenhouse gas footprints than retail stores.
- Ordering online from retail stores has an even smaller footprint than going to the store yourself.
- Greening efforts by major e-commerce sites won't curb wasteful consumer habits.
A pile of recycled cardboard sits on the ground at Recology's Recylce Central on January 4, 2018 in San Francisco, California.
Photo by Justin Sullivan/Getty Images<p>A large part of the reason is speed. In a competitive market, pure players use the equation, <em>speed + convenience</em>, to drive adoption. This is especially relevant to the "last mile" GHG footprint: the distance between the distribution center and the consumer.</p><p>Interestingly, the smallest GHG footprint occurs when you order directly from a physical store—even smaller than going there yourself. Pure players, such as Amazon, are the greatest offenders. Variables like geographic location matter; the team looked at shopping in the UK, the US, China, and the Netherlands. </p><p>Sadegh Shahmohammadi, a PhD student at the Netherlands' Radboud University and corresponding author of the paper, <a href="https://www.cnn.com/2020/02/26/tech/greenhouse-gas-emissions-retail/index.html" target="_blank">says</a> the above "pattern holds true in countries where people mostly drive. It really depends on the country and consumer behavior there."</p><p>The researchers write that this year-and-a-half long study pushes back on previous research that claims online shopping to be better in terms of GHG footprints.</p><p style="margin-left: 20px;">"They have, however, compared the GHG emissions per shopping event and did not consider the link between the retail channels and the basket size, which leads to a different conclusion than that of the current study."</p><p>Online retail is where convenience trumps environment: people tend to order one item at a time when shopping on pure player sites, whereas they stock up on multiple items when visiting a store. Consumers will sometimes order a number of separate items over the course of a week rather than making one trip to purchase everything they need. </p><p>While greening efforts by online retailers are important, until a shift in consumer attitude changes, the current carbon footprint will be a hard obstacle to overcome. Amazon is trying to have it both ways—carbon-free and convenience addicted—and the math isn't adding up. </p><p>--</p><p><em>Stay in touch with Derek on <a href="http://www.twitter.com/derekberes" target="_blank">Twitter</a>, <a href="https://www.facebook.com/DerekBeresdotcom" target="_blank">Facebook</a> and <a href="https://derekberes.substack.com/" target="_blank">Substack</a>. His next book is</em> "<em>Hero's Dose: The Case For Psychedelics in Ritual and Therapy."</em></p>
Chronic irregular sleep in children was associated with psychotic experiences in adolescence, according to a recent study out of the University of Birmingham's School of Psychology.
A time for sleep<div class="rm-shortcode" data-media_id="Mt29uUqI" data-player_id="FvQKszTI" data-rm-shortcode-id="931343dee3c02121445e51e94ba22446"> <div id="botr_Mt29uUqI_FvQKszTI_div" class="jwplayer-media" data-jwplayer-video-src="https://content.jwplatform.com/players/Mt29uUqI-FvQKszTI.js"> <img src="https://cdn.jwplayer.com/thumbs/Mt29uUqI-1920.jpg" class="jwplayer-media-preview" /> </div> <script src="https://content.jwplatform.com/players/Mt29uUqI-FvQKszTI.js"></script> </div> <p>Previous studies had already suggested a link between persistent nightmares in childhood and psychosis and borderline personality disorder (BPD) by adolescence, but researchers at the University of Birmingham's School of Psychology wanted to see if a similar connection existed between these mental disorders and other childhood behavioral sleep problems.</p><p>To do this, they scoured data from the Avon Longitudinal Study of Parents and Children, a longitudinal cohort study that followed approximately 14,000 children born in Avon, England, in the early '90s. The study followed the children for more than 13 years. During that time, mothers filled out questionnaires asking about the children's lives. Factors looked at included housing, parenting, nutrition, physical health, mental wellbeing, environmental exposures, and so on. </p><p>The cohort study inquired about sleep routines, sleep duration, and awakening frequency when their children were 6, 18, and 30 months old, and then again at 3.5, 4.8, and 5.8 years. It also assessed mental health in adolescence using semi-structured interviews, such as the Psychosis-Like Symptom Interview.</p><p>"We know that adolescence is a key developmental period to study the onset of many mental disorders, including psychosis or BPD. This is because of particular brain and hormonal changes which occur at this stage," <a href="https://www.birmingham.ac.uk/staff/profiles/psychology/marwaha-steven.aspx" target="_blank">Steven Marwaha</a>, professor of psychiatry at Birmingham and senior author on the study, <a href="https://www.sciencedaily.com/releases/2020/07/200701125431.htm" target="_blank">said in a release</a>. "Sleep may be one of the most important underlying factors—and it's one that we can influence with effective, early interventions, so it's important that we understand these links."</p><p>After compiling the data, the researchers discovered an association between children with irregular sleeping patterns and teenagers with <a href="https://www.mind.org.uk/information-support/types-of-mental-health-problems/psychosis/about-psychosis/" target="_blank">psychotic experiences</a>—that is, episodes when the person perceives reality differently than those around them. Even when depression at 10 years old was considered as a mediating factor, their findings still suggested "a specific pathway between these childhood sleep problems and adolescent psychotic experiences." </p><p>Toddlers with shorter nighttime sleep duration and late bedtimes were likewise associated with a <a href="https://www.nimh.nih.gov/health/topics/borderline-personality-disorder/index.shtml" target="_blank">borderline personality disorder</a>—an disorder marked by a pattern of varying moods, self-images, and behaviors—in their teenage years. Depression at age 10 did not mediate this particular association, suggesting a separate and more specific pathway. </p>
A more restful tomorrow<p>While the sample size was large and mental health was assessed with a validated interview, there nevertheless remain limitations to this data. For starters, sleep habits were based on mothers' reports. Because they came from memory, versus a more direct observation method such as actigraphy, these data may be prone to imperfect recollection and reporting error. There are also many confounders that could be secretly nudging the results, such as family conditions, prenatal medicines, and a host of environmental factors. Finally, <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024884/#:~:text=Sleep%20difficulties%20in%20youth%20with,fear%20of%20dark%20%5B13%5D." target="_blank">the relationship between sleep problems and mental disorders</a> is both complex and two-way.</p><p>As such, the study shows an association between poor childhood sleep later mental disorders but does not prove a causal link. Parents need not worry that a string of nightmares or the eternal struggle settle into bed will be the first ingredients in a witches' brew of debilitating mental disorders. The goal of the study, the researchers point out, is not to create undue worry but improve our ability to recognize the signs of at-risk children and deliver necessary interventions earlier.</p><p>"The results of this study could have important implications for helping practitioners identify children who might be at higher risk for psychotic experiences or BPD symptoms in adolescence, and potentially lead to the design of more effectively targeted sleep or psychological interventions to prevent the onset or attenuate these mental disorders," Isabel Morales-Muñoz, the study's lead researcher, <a href="https://www.healio.com/news/psychiatry/20200702/childhood-sleep-problems-linked-to-adolescent-psychosis-borderline-personality-disorder#:~:text=Sleep%20problems%20during%20early%20childhood,study%20published%20in%20JAMA%20Psychiatry." target="_blank">told <em>Healio Psychiatry</em></a>.</p><p>If a parent reading this is worried that their child's sleep patterns are deleterious, the take away should not be despair over an unyielding fate. It should be to seek professional help as soon as possible to begin improving sleep duration and quality. Even if you aren't worried, it's worth remembering that childhood experiences lay the foundation for a lifetime of salubrious sleeping habits. It's so much more than beauty rest.</p>
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