Enjoy the pleasure of Mabinogi

I have many classmate and friends who like to play the game. We usually play the game together. We often talk the game information, sharing the game experience. I have one classmate who was a professional player. At the beginning of the game, I had to buy a key, including six in one group. If I buy a new one for my classmate he can play it without payment for one month. That means the player come from all over the world. No matter where you are from, all over the player key play in the same game. mabinogi gold is same. But there are cheaper or expensive gold. The European gold is most expensive. The European banned account was lower than American in the present two years. So I suggest him to buy the European key. But I am not sure it will not be banned. I have a classmate who was a new player. So one month is the least for him. He often asks help online. In fact, if the player was a professor he can play on three computers at the same time. He has to buy equipment when he was playing the level. He can not product mabinogi money so he has to buy mabinogi gold. The cost was a little great. So every player has to prepare some money for the gold. The game do not need agent. It is easy for him to play.He owns his things in the game. There are lots of items in his warehouse. He can have his own shop. He can sell some items in his shop. Others can check the price of the items in his shop. If some one buys the item my class selling he will get mabinogi online gold at once. He plays the game better than others. The account level is same as the original one. Every character has his skill. He can attack others if he has some strength skill. He can win others if he has AGI skill. When fighting with others he can move faster, protect him efficiently. And he can make money selling the skill. He can show his skill to others to make honor. He has a bird that can fly faster. It can take the player to somewhere he wants. The requirement is he must be 20 levels. The play must have the driving license then he can drive the bird. The price is a little high. The player can never get the bird as a vehicle in cheap mabinogi. I do not use the bird often. 

3D printing might save your life one day. It's transforming medicine and health care.

What can 3D printing do for medicine? The "sky is the limit," says Northwell Health researcher Dr. Todd Goldstein.

Northwell Health
Sponsored by Northwell Health
  • Medical professionals are currently using 3D printers to create prosthetics and patient-specific organ models that doctors can use to prepare for surgery.
  • Eventually, scientists hope to print patient-specific organs that can be transplanted safely into the human body.
  • Northwell Health, New York State's largest health care provider, is pioneering 3D printing in medicine in three key ways.
Keep reading Show less

Where do atoms come from? Billions of years of cosmic fireworks.

The periodic table was a lot simpler at the beginning of the universe.

10 excerpts from Marcus Aurelius' 'Meditations' to unlock your inner Stoic

Great ideas in philosophy often come in dense packages. Then there is where the work of Marcus Aurelius.

(Getty Images)
Personal Growth
  • Meditations is a collection of the philosophical ideas of the Roman Emperor Marcus Aurelius.
  • Written as a series of notes to himself, the book is much more readable than the dry philosophy most people are used to.
  • The advice he gave to himself 2,000 years ago is increasingly applicable in our hectic, stressed-out lives.
Keep reading Show less

An organism found in dirt may lead to an anxiety vaccine, say scientists

Can dirt help us fight off stress? Groundbreaking new research shows how.

University of Colorado Boulder
Surprising Science
  • New research identifies a bacterium that helps block anxiety.
  • Scientists say this can lead to drugs for first responders and soldiers, preventing PTSD and other mental issues.
  • The finding builds on the hygiene hypothesis, first proposed in 1989.

Are modern societies trying too hard to be clean, at the detriment to public health? Scientists discovered that a microorganism living in dirt can actually be good for us, potentially helping the body to fight off stress. Harnessing its powers can lead to a "stress vaccine".

Researchers at the University of Colorado Boulder found that the fatty 10(Z)-hexadecenoic acid from the soil-residing bacterium Mycobacterium vaccae aids immune cells in blocking pathways that increase inflammation and the ability to combat stress.

The study's senior author and Integrative Physiology Professor Christopher Lowry described this fat as "one of the main ingredients" in the "special sauce" that causes the beneficial effects of the bacterium.

The finding goes hand in hand with the "hygiene hypothesis," initially proposed in 1989 by the British scientist David Strachan. He maintained that our generally sterile modern world prevents children from being exposed to certain microorganisms, resulting in compromised immune systems and greater incidences of asthma and allergies.

Contemporary research fine-tuned the hypothesis, finding that not interacting with so-called "old friends" or helpful microbes in the soil and the environment, rather than the ones that cause illnesses, is what's detrimental. In particular, our mental health could be at stake.

"The idea is that as humans have moved away from farms and an agricultural or hunter-gatherer existence into cities, we have lost contact with organisms that served to regulate our immune system and suppress inappropriate inflammation," explained Lowry. "That has put us at higher risk for inflammatory disease and stress-related psychiatric disorders."

University of Colorado Boulder

Christopher Lowry

This is not the first study on the subject from Lowry, who published previous work showing the connection between being exposed to healthy bacteria and mental health. He found that being raised with animals and dust in a rural environment helps children develop more stress-proof immune systems. Such kids were also likely to be less at risk for mental illnesses than people living in the city without pets.

Lowry's other work also pointed out that the soil-based bacterium Mycobacterium vaccae acts like an antidepressant when injected into rodents. It alters their behavior and has lasting anti-inflammatory effects on the brain, according to the press release from the University of Colorado Boulder. Prolonged inflammation can lead to such stress-related disorders as PTSD.

The new study from Lowry and his team identified why that worked by pinpointing the specific fatty acid responsible. They showed that when the 10(Z)-hexadecenoic acid gets into cells, it works like a lock, attaching itself to the peroxisome proliferator-activated receptor (PPAR). This allows it to block a number of key pathways responsible for inflammation. Pre-treating the cells with the acid (or lipid) made them withstand inflammation better.

Lowry thinks this understanding can lead to creating a "stress vaccine" that can be given to people in high-stress jobs, like first responders or soldiers. The vaccine can prevent the psychological effects of stress.

What's more, this friendly bacterium is not the only potentially helpful organism we can find in soil.

"This is just one strain of one species of one type of bacterium that is found in the soil but there are millions of other strains in soils," said Lowry. "We are just beginning to see the tip of the iceberg in terms of identifying the mechanisms through which they have evolved to keep us healthy. It should inspire awe in all of us."

Check out the study published in the journal Psychopharmacology.