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What If Tattoos Gave You Updates about Your Health?
Researchers at MIT and Harvard Medical School have developed a tattoo ink that could potentially be used to monitor medical conditions, with ink that changes in response to physical conditions.
Sorry, Fitbit. We may soon have a battery-free wearable device that monitors your health--a bio-sensing tattoo.
Researchers at MIT and Harvard Medical School recently announced the development of the "Dermal Abyss," a health-monitoring tattoo that can turn your body surface into an interactive display. It is a development that should excite biohackers and transhumanists, but also have potentially large mainstream applications.
By tattooing optical biosensors into the skin, the tattoo can react to changes in your body's interstitial fluid. The Dermal Abyss may solve a major problem: how to create a health-monitoring tool that is easy to wear, bio-compatible, and has access to the relevant bio-markers?
The Need for Better Health Monitoring Tools
As we have seen in the market for wearable devices and other monitoring tools, there is a desire to measure glucose levels, blood pressure, skin temperature, and brain activity. While there are currently silicon-based implantable devices, these would not be considered bio-compatible. The implantable devices lack of smooth integration in one's daily life also discourages its use.
According to the marketing research firm Kalorama Information, the market for health-monitoring wearable devices surpassed $13 billion in 2016. Despite their success, there have been major questions around the the merit of the data being tracked and shown to consumers. Popular wearable devices like Fitbit may give the impression of accuracy, but often do not have direct access to the relevant bio-markers. For example, a 2016 study by Ball State University found that the Fitbit Charge HR often missed heartbeats. In the study, the device had an average heartbeat error of 14 percent.
How Does the Dermal Abyss Work?
The Dermal Abyss works by swapping out the traditional inks of tattoos with bio-sensing inks. These bio-sensing inks alter color in response the the intestinal fluid. As the picture above shows, the pH sensor changes colors for indicators such as glucose, sodium, and fluoresce. While some color changes could be noticed by the naked eye, other color changes would be seen by using a blue light. The Dermal Abyss was developed as a proof of concept, being made on pigskin. In order for a health-monitoring tattoo to be ready for market, more durable inks that do not fade as quickly would need to be developed.
"By featuring tissue cells with interactive properties, the skin can change its color, light intensity, or structure to display information. Hence, the skin cells become a pixel screen to be decoded by the user, other viewers, or cameras." -"The Dermal Abyss: Interfacing with the Skin by Tattooing Biosensors"
Will the Dermal Abyss Creep People Out?
While the visual of the tattoo altering color is griping, the possibility of health-monitoring tattoos doesn't create the same level of unease for me that, let's say, microchipping does. Whereas microchipping can cross the "cyborg threshold," and offend the notions of our humanness, the Dermal Abyss builds on the body modification process of tattooing that has been done for thousands of years.
Where you for foresee unease with advances like the Dermal Abyss, however, is in the continued erosion with personal health indicators from something private to something made public. That tends to be our unease with how health-monitoring tools are utilized by empowers--transitioning from a well-intended incentive to be healthy, towards a more worrisome way to discriminate. Our personal health is something that we like to have full control over how--and with who--we share the information. One consideration of the Dermal Abyss is whether the color changes should be noticeable by the naked eye, or be more of an invisible ink where a special light is needed.
“The purpose of the work is to light the imagination of biotechnologists and stimulate public support for such efforts. These questions of how technology impacts our lives must be considered as carefully as the design of the molecular sensors patients may someday carry embedded in their skin.” -Nan Jiang, Harvard Medical School, who worked on the Dermal Abyss (speaking to the Harvard Gazette)
Our skin has always acted as an indicator to our underlying health, with subtle changes to color and temperature. Outside of the medical field, there was always a level of guesswork with the process (i.e. "Are you okay? You look sick today). It would be a whole lot more interesting if a person was literally wearing their health.
A team of archaeologists has discovered 3,200-year-old cheese after analyzing artifacts found in an ancient Egyptian tomb. It could be the oldest known cheese sample in the world.
A team of archaeologists has discovered 3,200-year-old cheese after analyzing artifacts found in an ancient Egyptian tomb. It could be the oldest known cheese sample in the world.
The tomb that held the cheese lies in the desert sands south of Cairo. It was first discovered in the 19th century by treasure hunters, who eventually lost the knowledge of its location, leaving the Saharan sands to once again conceal the tomb.
“Since 1885 the tomb has been covered in sand and no-one knew about it,” Professor Ola el-Aguizy of Cairo University told the BBC. “It is important because this tomb was the lost tomb.”
In 2010, a team of archaeologists rediscovered the tomb, which belonged to Ptahmes, a mayor and military chief of staff of the Egyptian city of Memphis in the 13th century B.C. In the tomb, the team found a jar containing a “solidified whitish mass,” among other artifacts.
“The archaeologists suspected [the mass] was food, according to the conservation method and the position of the finding inside the tomb, but we discovered it was cheese after the first tests,” Enrico Greco, the lead author of the paper and a research assistant at Peking University in Beijing, told the The New York Times.
To find out what the substance was, the team had to develop a novel way to analyze the proteins and identify the peptide markers in the samples. They first dissolved parts of the substance and then used mass spectrometry and chromatography to analyze its proteins.
Despite more than 3,000 years spent in the desert, the researchers were able to identify hundreds of peptides (chains of amino acids) in the sample. They found some that were associated with milk from goat, sheep and, interestingly, the African buffalo, a species not usually kept as a domestic animal in modern Africa, as Gizmodo reports.
Those results suggested that the substance was cheese, specifically one that was probably similar in consistency to chevre but with a “really, really acidy” taste, as Dr. Paul Kindstedt, a professor at the University of Vermont who studies the chemistry and history of cheese, told the The New York Times.
“It would be high in moisture; it would be spreadable,” he said. “It would not last long; it would spoil very quickly.”
The researchers also found traces of the bacterium Brucella melitensis, which causes brucellosis, a debilitating disease that can cause endocarditis, arthritis, chronic fatigue, malaise, muscle pain and other conditions. It’s a disease usually contracted by consuming raw dairy products.
“The most common way to be infected [with Brucella melitensis] is by eating or drinking unpasteurized/raw dairy products. When sheep, goats, cows, or camels are infected, their milk becomes contaminated with the bacteria,” the U.S. Centers for Disease Control wrote on its website. “If the milk from infected animals is not pasteurized, the infection will be transmitted to people who consume the milk and/or cheese products.”
Dr. Kindstedt said one reason the study is significant is for its novel use of proteomic analysis, which is the systematic identification and quantification of the complete complement of proteins (the proteome) of a biological system.
“As I say to my students every year when I get to Egypt, someone has to go ahead and analyze these residues with modern capabilities,” he told the The New York Times. “This is a logical next step and I think you’re going to see a lot more of this.”
'The Great Pyramid of Chee-za'. An artist's interpretation of a very ripe, slightly deadly Egyptian tomb cheese. (Credit: Creative commons/Big Think)
However, Dr. Kindstedt did offer a bit of caution on the conclusions the researchers drew from the findings.
“The authors of this new study did some nice work,” he told Gizmodo in a statement. “But in my view, on multiple grounds (I suspect in their zeal to be “the first”), they inferred considerably beyond what their data is capable of supporting within reasonable certainty, and almost certainly they are not the first to have found solid cheese residues in Egyptian tombs, just the first to apply proteomic analyses (which is worthy achievement on its own).”
As bad as this sounds, a new essay suggests that we live in a surprisingly egalitarian age.
- A new essay depicts 700 years of economic inequality in Europe.
- The only stretch of time more egalitarian than today was the period between 1350 to approximately the year 1700.
- Data suggest that, without intervention, inequality does not decrease on its own.
Economic inequality is a constant topic. No matter the cycle — boom or bust — somebody is making a lot of money, and the question of fairness is never far behind.
A recently published essay in the Journal of Economic Literature by Professor Guido Alfani adds an intriguing perspective to the discussion by showing the evolution of income inequality in Europe over the last several hundred years. As it turns out, we currently live in a comparatively egalitarian epoch.
Seven centuries of economic history
Figure 8 from Guido Alfani, Journal of Economic Literature, 2021.
This graph shows the amount of wealth controlled by the top ten percent in certain parts of Europe over the last seven hundred years. Archival documentation similar to — and often of a similar quality as — modern economic data allows researchers to get a glimpse of what economic conditions were like centuries ago. Sources like property tax records and documents listing the rental value of homes can be used to determine how much a person's estate was worth. (While these methods leave out those without property, the data is not particularly distorted.)
The first part of the line, shown in black, represents work by Prof. Alfani and represents the average inequality level of the Sabaudian State in Northern Italy, The Florentine State, The Kingdom of Naples, and the Republic of Venice. The latter part, in gray, is based on the work of French economist Thomas Piketty and represents an average of inequality in France, the United Kingdom, and Sweden during that time period.
Despite the shift in location, the level of inequality and rate of increase are very similar between the two data sets.
Apocalyptic events cause decreases in inequality
Note that there are two substantial declines in inequality. Both are tied to truly apocalyptic events. The first is the Black Death, the common name for the bubonic plague pandemic in the 14th century, which killed off anywhere between 30 and 50 percent of Europe. The second, at the dawn of the 20th century, was the result of World War I and the many major events in its aftermath.
The 20th century as a whole was a time of tremendous economic change, and the periods not featuring major wars are notable for having large experiments in distributive economic policies, particularly in the countries Piketty considers.
The slight stall in the rise of inequality during the 17th century is the result of the Thirty Years' War, a terrible religious conflict that ravaged Europe and left eight million people dead, and of major plagues that affected South Europe. However, the recurrent outbreaks of the plague after the Black Death no longer had much effect on inequality. This was due to a number of factors, not the least of which was the adaptation of European institutions to handle pandemics without causing such a shift in wealth.
In 2010, the last year covered by the essay, inequality levels were similar to those of 1340, with 66 percent of the wealth of society being held by the top ten percent. Also, inequality levels were continuing to rise, and the trends have not ended since. As Prof. Alfani explained in an email to BigThink:
"During the decade preceding the Covid pandemic, economic inequality has shown a slow tendency towards further inequality growth. The Great Recession that began in 2008 possibly contributed to slow down inequality growth, especially in Europe, but it did not stop it. However, the expectation is that Covid-19 will tend to increase inequality and poverty. This, because it tends to create a relatively greater economic damage to those having unstable occupations, or who need physical strength to work (think of the effects of the so-called "long-Covid," which can prove physically invalidating for a long time). Additionally, and thankfully, Covid is not lethal enough to force major leveling dynamics upon society."
Can only disasters change inequality?
That is the subject of some debate. While inequality can occur in any economy, even one that doesn't grow all that much, some things appear to make it more likely to rise or fall.
Thomas Piketty suggested that the cause of changes in inequality levels is the difference in the rate of return on capital and the overall growth rate of the economy. Since the return on capital is typically higher than the overall growth rate, this means that those who have capital to invest tend to get richer faster than everybody else.
While this does explain a great deal of the graph after 1800, his model fails to explain why inequality fell after the Black Death. Indeed, since the plague destroyed human capital and left material goods alone, we would expect the ratio of wealth over income to increase and for inequality to rise. His model can provide explanations for the decline in inequality in the decades after the pandemic, however- it is possible that the abundance of capital could have lowered returns over a longer time span.
The catastrophe theory put forth by Walter Scheidel suggests that the only force strong enough to wrest economic power from those who have it is a world-shattering event like the Black Death, the fall of the Roman Empire, or World War I. While each event changed the world in a different way, they all had a tremendous leveling effect on society.
But not even this explains everything in the above graph. Pandemics subsequent to the Black Death had little effect on inequality, and inequality continued to fall for decades after World War II ended. Prof. Alfani suggests that we remember the importance of human agency through institutional change. He attributes much of the post-WWII decline in inequality to "the redistributive policies and the development of the welfare states from the 1950s to the early 1970s."
What does this mean for us now?
As Professor Alfani put it in his email:
"[H]istory does not necessarily teach us whether we should consider the current trend toward growth in economic inequality as an undesirable outcome or a problem per se (although I personally believe that there is some ground to argue for that). Nor does it teach us that high inequality is destiny. What it does teach us, is that if we do not act, we have no reason whatsoever to expect that inequality will, one day, decline on its own. History also offers abundant evidence that past trends in inequality have been deeply influenced by our collective decisions, as they shaped the institutional framework across time. So, it is really up to us to decide whether we want to live in a more, or a less unequal society."
Our love-hate relationship with browser tabs drives all of us crazy. There is a solution.
- A new study suggests that tabs can cause people to be flustered as they try to keep track of every website.
- The reason is that tabs are unable to properly organize information.
- The researchers are plugging a browser extension that aims to fix the problem.
A lot of ideas that people had about the internet in the 1990s have fallen by the wayside as technology and our usage patterns evolved. Long gone are things like GeoCities, BowieNet, and the belief that letting anybody post whatever they are thinking whenever they want is a fundamentally good idea with no societal repercussions.
While these ideas have been abandoned and the tools that made them possible often replaced by new and improved ones, not every outdated part of our internet experience is gone. A new study by a team at Carnegie Mellon makes the case that the use of tabs in a web browser is one of these outdated concepts that we would do well to get rid of.
How many tabs do you have open right now?
We didn't always have tabs. Introduced in the early 2000s, tabs are now included on all major web browsers, and most users have had access to them for a little over a decade. They've been pretty much the same since they came out, despite the ever changing nature of the internet. So, in this new study, researchers interviewed and surveyed 113 people on their use of — and feelings toward — the ubiquitous tabs.
Most people use tabs for the short-term storage of information, particularly if it's information that is needed again soon. Some keep tabs that they know they'll never get around to reading. Others used them as a sort of external memory bank. One participant described this action to the researchers:
"It's like a manifestation of everything that's on my mind right now. Or the things that should be on my mind right now... So right now, in this browser window, I have a web project that I'm working on. I don't have time to work on it right now, but I know I need to work on it. So it's sitting there reminding me that I need to work on it."
You suffer from tab overload
Unfortunately, trying to use tabs this way can cause a number of problems. A quarter of the interview subjects reported having caused a computer or browser to crash because they had too many tabs open. Others reported feeling flustered by having so many tabs open — a situation called "tab overload" — or feeling ashamed that they appeared disorganized by having so many tabs up at once. More than half of participants reported having problems like this at least two or three times a week.
However, people can become emotionally invested in the tabs. One participant explained, "[E]ven when I'm not using those tabs, I don't want to close them. Maybe it's because it took efforts [sic] to open those tabs and organize them in that way."
So, we have a tool that inefficiently saves web pages that we might visit again while simultaneously reducing our productivity, increasing our anxiety, and crashing our machines. And yet we feel oddly attached to them.
Either the system is crazy or we are.
Skeema: The anti-tab revolution
The researchers concluded that at least part of the problem is caused by tabs not being an ideal way of organizing the work we now do online. They propose a new model that better compartmentalizes tabs by task and subtask, reflects users' mental models, and helps manage the users' attention on what is important right now rather than what might be important later.
To that end, the team also created Skeema, an extension for Google Chrome, that treats tabs as tasks and offers a variety of ways to organize them. Users of an early version reported having fewer tabs and windows open at one time and were better able to manage the information they contained.
Tabs were an improvement over having multiple windows open at the same time, but they may have outlived their usefulness. While it might take a paradigm shift to fully replace the concept, the study suggests that taking a different approach to tabs might be worth trying.
And now, excuse me, while I close some of the 87 tabs I currently have open.