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How psychedelics help you "die before you die"
The heart of the religious ritual is mysticism, argues Brian Muraresku in "The Immortality Key."
- The concept of "dying before you die" lies at the heart of religious tradition, argues Brian Muraresku.
- This secret ritual connects the Eleusinian Mysteries with the origins of Christianity.
- In "The Immortality Key," Muraresku speculates that psychedelic wine could have been the original Christian Eucharist.
After a 20-year ban on clinical psychedelics research, the U.S. government approved trials on DMT in 1990. At first, Rick Strassman, a clinical associate professor of psychiatry at the University of New Mexico School of Medicine, only wanted to study the physiological strain of injecting DMT: heart rate, blood pressure, and so on. Given that psychedelics had been contentiously demonized for a generation, he wondered if physical consequences were as dangerous as advertised.
LSD had been administered tens of thousands of times in the 1950s and early 1960s. Did it really fry your brain like eggs, as the Reagans so confidently declared?
Over the next five years, Strassman administered 400 doses of N,N-dimethyltryptamine (DMT) to over 50 volunteers. It turned out that DMT, the fast-acting psychoactive ingredient in ayahuasca—the "soul vine" persists for hours only when blended with MAOIs to slow the breakdown of enzymes in your gut—has few negative effects. A longtime Zen Buddhist practitioner, Strassman noticed something else going on when over half of participants reported having profound religious experiences.
They were dying before dying.
Well, some of them were being visited by alien creatures, a phenomenon MAPS founder Rick Doblin possibly attributes to the "setting" part of "set and setting": tripping out in a sterile hospital room surrounded by clinicians in white lab coats certainly felt foreign, perhaps otherworldly. Other volunteers saw a beautiful light at the end of a tunnel and returned—a sensation noted in the ayahuasca literature for as long as we have records.
DMT is chemically related to serotonin and melatonin. The latter hormone is produced by the pineal gland, which is symbolically called the "third eye"—Descartes famously called it the "seat of the soul." Since every mammal that's been tested (including humans) produce endogenous DMT, could our third eye possibly release this structural analog of tryptamine at death? Is it a coincidence that the pineal gland, according to Strassman, appears in fetuses at 49 days, the exact duration of the "passage" of souls described in The Tibetan Book of the Dead?
Strassman admits this is speculation. The anecdotes are irrefutable, however. His clinical work led to Charles Grob's government-approved research on ayahuasca and MDMA in the 1990s, which opened the door to Johns Hopkins researchers studying psilocybin to treat the existential dread hospice patients encounter, which opened the floodgates to the psychedelic revolution occurring today.That initial Johns Hopkins study, which found that psilocybin (structurally similar to DMT) eases distress by helping initiates die before they die, helped give form to Brian Muraresku's 12-year journey while writing his debut book, "The Immortality Key: The Secret History of the Religion With No Name."
Brian Muraresku explains the potential role of psychedelics in Christianity
Muraresku has been getting a lot of press since the book's publication, in part boosted by his appearance on Joe Rogan's podcast. The classicist speculates that the Christian Eucharist is rooted in the Eleusinian Mysteries, which may have involved the ceremonial ingestion of wine spiked with psychedelic ingredients. The idea of a psychedelic Christianity is not new, but Muraresku brings a detailed level of scholarship and compassion to the topic.
As he told me in a recent interview, the "immortality key" is not psychedelics, but the concept of dying before dying. He opens his book with a Greek inscription: "If you die before you die / You won't die when you die." Muraresku, a devout Catholic raised in the Jesuit tradition, kicks off the discussion with an atheist from the Johns Hopkins trial. Despite her lack of faith, she felt an "overwhelming, all-encompassing love" that helped her deal with the inevitable consequences of mixed-cell ovarian cancer—really, the inevitable consequences of being an animal bound to die.
The Hopkins study went mainstream when Michael Pollan wrote about it in the New Yorker. The results were stunning: 70 percent of participants felt a single dose of psilocybin produced the most meaningful (or among the top five) experience of their lives. Interestingly, the same result occurred after the famous Marsh Chapel experiment, when Timothy Leary and friends dosed Harvard Divinity School grad students with psilocybin; a quarter-century later, all but one rated the event in their top five.
Not only do you die before you die while under the influence of psychedelics, but you also gain a new perspective on life. The ego death that occurs during the ritual changes their orientation about existence. And what good is a religious experience if it can't be applied to living?
As Muraresku told me,
"[Psychedelics] is one tool in the Spiritual Toolkit. What I mean by 'the key' is in Greek, which is preserved at St. Paul's monastery: if you die before you die, you won't die when you die. That's the actual key. It's not psychedelics, it's not drugs; it's this concept of navigating the liminal space between what you and I are doing right now, and dreaming and death. In that state, the mystics and sages tell us, is the potential to grasp a very different view of reality."Muraresku taps into a growing consensus that humans are "wired" for mystical experiences. He points to lead Johns Hopkins researcher, Roland Griffiths, who believes that mysticism is included in our operating system at birth. You just have to turn it on. While the effects of psychedelics can be replicated through the more arduous path of meditation, in the right set and setting anyone can tap into mystical states of consciousness. Psychedelics provide a shortcut to these states.
Credit: Galyna Andrushko / Adobe Stock
Western religious leaders, especially those in Christianity and Islam, treat their prophets as standalone figures. The best you can hope for is being granted access to some special place after you die. Gnostics and Sufis—sects within those faiths that attempt to replicate their prophet's mysticism—are considered outcasts by mainstream religious figures. In some circumstances, they're outlawed, threatened, or even killed for their supposed heresy.
Sufis might spin for hours in ecstatic rapture to reach this mystical state, but as Muraresku's extensive research shows, psychedelics also tap into this "secret" knowledge that he believes to be at the heart of Christian—and if we extrapolate, religious—tradition. And to him, this is the essence of the religion, not a byproduct of the real faith.
"I didn't write this book to be anti-organized religion. In some cases, it's the exact opposite. In the intro, I mentioned Brother David Steindl-Rast, a Benedictine monk who is a hero of mine. He talks about the tension between mystics and the dogma and doctrine of organized faith. I don't think you can have one without the other. The balance, as Brother David says, is to rediscover that original visionary power and live in it as a lived experience. This is what Joseph Campbell says of religion being a lived experience. We're talking about emotional potential. That's how the great anthropologist Clifford Geertz defines religion: these powerful, pervasive, long-lasting moods and motivations. That only happens when you're talking about something that gets inside of people's bones. That's what the mystical experience is; it's how these religions are born. Brother David says it's virtually impossible to start a religion without mystical experience, like Moses in the burning bush, Paul on the road to Damascus, or Peter, in Acts, caught up in a trance."
Campbell's conversation with Bill Moyers in "The Power of Myth" nicely ties together this idea:
"People say that what we're all seeking is a meaning for life. I don't think that's what we're really seeking. I think that what we're seeking is an experience of being alive, so that our life experiences on the purely physical plane will have resonances with our own innermost being and reality, so that we actually feel the rapture of being alive."
The mythologist also advocated for a reformation of religion every generation so that the faith speaks to the times. This is effectively what Muraresku advocates for in "The Immortality Key": an honest conversation regarding the historical circumstances that birthed the world's most-followed religion in the hopes of applying the foundational lessons to our current reality. If that means a psychedelic ritual that shows you how to die before you die so that you may better know how to live, then it's time to rethink the role of the sacrament.
Mysticism is a universal phenomenon. The "eternal return" Mircea Eliade wrote about has been experienced throughout history in disparate regions of the world. As Strassman's and Griffiths's work shows, we retain the capability of dying before dying. In fact, current research on psilocybin, LSD, iboga, DMT, and ayahuasca show that these substances are helping people gain a perspective of their lives, be it in depression treatment, addiction recovery, or easing the pain of hospice care. A little mysticism goes a long way.
Let's move beyond this notion that mysticism only applies to a chosen few. In fact, let's reconsider the role of consciousness in general. Every religion has its own take on what happens after we die. Yet we have tools at our disposal to show us how to exist now: a living religion that speaks to the entire planet.
Stay in touch with Derek on Twitter and Facebook. His new book is "Hero's Dose: The Case For Psychedelics in Ritual and Therapy."
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Northwell Health is using insights from website traffic to forecast COVID-19 hospitalizations two weeks in the future.
- The machine-learning algorithm works by analyzing the online behavior of visitors to the Northwell Health website and comparing that data to future COVID-19 hospitalizations.
- The tool, which uses anonymized data, has so far predicted hospitalizations with an accuracy rate of 80 percent.
- Machine-learning tools are helping health-care professionals worldwide better constrain and treat COVID-19.
The value of forecasting<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNTA0Njk2OC9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYyMzM2NDQzOH0.rid9regiDaKczCCKBsu7wrHkNQ64Vz_XcOEZIzAhzgM/img.jpg?width=980" id="2bb93" class="rm-shortcode" data-rm-shortcode-id="31345afbdf2bd408fd3e9f31520c445a" data-rm-shortcode-name="rebelmouse-image" data-width="1546" data-height="1056" />
Northwell emergency departments use the dashboard to monitor in real time.
Credit: Northwell Health<p>One unique benefit of forecasting COVID-19 hospitalizations is that it allows health systems to better prepare, manage and allocate resources. For example, if the tool forecasted a surge in COVID-19 hospitalizations in two weeks, Northwell Health could begin:</p><ul><li>Making space for an influx of patients</li><li>Moving personal protective equipment to where it's most needed</li><li>Strategically allocating staff during the predicted surge</li><li>Increasing the number of tests offered to asymptomatic patients</li></ul><p>The health-care field is increasingly using machine learning. It's already helping doctors develop <a href="https://care.diabetesjournals.org/content/early/2020/06/09/dc19-1870" target="_blank">personalized care plans for diabetes patients</a>, improving cancer screening techniques, and enabling mental health professionals to better predict which patients are at <a href="https://healthitanalytics.com/news/ehr-data-fuels-accurate-predictive-analytics-for-suicide-risk" target="_blank" rel="noopener noreferrer">elevated risk of suicide</a>, to name a few applications.</p><p>Health systems around the world have already begun exploring how <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315944/" target="_blank" rel="noopener noreferrer">machine learning can help battle the pandemic</a>, including better COVID-19 screening, diagnosis, contact tracing, and drug and vaccine development.</p><p>Cruzen said these kinds of tools represent a shift in how health systems can tackle a wide variety of problems.</p><p>"Health care has always used the past to predict the future, but not in this mathematical way," Cruzen said. "I think [Northwell Health's new predictive tool] really is a great first example of how we should be attacking a lot of things as we go forward."</p>
Making machine-learning tools openly accessible<p>Northwell Health has made its predictive tool <a href="https://github.com/northwell-health/covid-web-data-predictor" target="_blank">available for free</a> to any health system that wishes to utilize it.</p><p>"COVID is everybody's problem, and I think developing tools that can be used to help others is sort of why people go into health care," Dr. Cruzen said. "It was really consistent with our mission."</p><p>Open collaboration is something the world's governments and health systems should be striving for during the pandemic, said Michael Dowling, Northwell Health's president and CEO.</p><p>"Whenever you develop anything and somebody else gets it, they improve it and they continue to make it better," Dowling said. "As a country, we lack data. I believe very, very strongly that we should have been and should be now working with other countries, including China, including the European Union, including England and others to figure out how to develop a health surveillance system so you can anticipate way in advance when these things are going to occur."</p><p>In all, Northwell Health has treated more than 112,000 COVID patients. During the pandemic, Dowling said he's seen an outpouring of goodwill, collaboration, and sacrifice from the community and the tens of thousands of staff who work across Northwell.</p><p>"COVID has changed our perspective on everything—and not just those of us in health care, because it has disrupted everybody's life," Dowling said. "It has demonstrated the value of community, how we help one another."</p>
Scientists used CT scanning and 3D-printing technology to re-create the voice of Nesyamun, an ancient Egyptian priest.
- Scientists printed a 3D replica of the vocal tract of Nesyamun, an Egyptian priest whose mummified corpse has been on display in the UK for two centuries.
- With the help of an electronic device, the reproduced voice is able to "speak" a vowel noise.
- The team behind the "Voices of the Past" project suggest reproducing ancient voices could make museum experiences more dynamic.
Howard et al.<p style="margin-left: 20px;">"While this approach has wide implications for heritage management/museum display, its relevance conforms exactly to the ancient Egyptians' fundamental belief that 'to speak the name of the dead is to make them live again'," they wrote in a <a href="https://www.nature.com/articles/s41598-019-56316-y#Fig3" target="_blank">paper</a> published in Nature Scientific Reports. "Given Nesyamun's stated desire to have his voice heard in the afterlife in order to live forever, the fulfilment of his beliefs through the synthesis of his vocal function allows us to make direct contact with ancient Egypt by listening to a sound from a vocal tract that has not been heard for over 3000 years, preserved through mummification and now restored through this new technique."</p>
Connecting modern people with history<p>It's not the first time scientists have "re-created" an ancient human's voice. In 2016, for example, Italian researchers used software to <a href="https://www.smithsonianmag.com/smart-news/hear-recreated-voice-otzi-iceman-180960570/" target="_blank">reconstruct the voice of Ötzi,</a> an iceman who was discovered in 1991 and is thought to have died more than 5,000 years ago. But the "Voices of the Past" project is different, the researchers note, because Nesyamun's mummified corpse is especially well preserved.</p><p style="margin-left: 20px;">"It was particularly suited, given its age and preservation [of its soft tissues], which is unusual," Howard told <em><a href="https://www.livescience.com/amp/ancient-egypt-mummy-voice-reconstructed.html" target="_blank">Live Science</a>.</em></p><p>As to whether Nesyamun's reconstructed voice will ever be able to speak complete sentences, Howard told <em><a href="https://abcnews.go.com/Weird/wireStory/ancient-voice-scientists-recreate-sound-egyptian-mummy-68482015" target="_blank">The Associated Press</a>, </em>that it's "something that is being worked on, so it will be possible one day."</p><p>John Schofield, an archaeologist at the University of York, said that reproducing voices from history can make museum experiences "more multidimensional."</p><p style="margin-left: 20px;">"There is nothing more personal than someone's voice," he told <em>The Associated Press.</em> "So we think that hearing a voice from so long ago will be an unforgettable experience, making heritage places like Karnak, Nesyamun's temple, come alive."</p>
A new study proposes mysterious axions may be found in X-rays coming from a cluster of neutron stars.
Are Axions Dark Matter?<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="5e35ce24a5b17102bfce5ae6aecc7c14"><iframe type="lazy-iframe" data-runner-src="https://www.youtube.com/embed/e7yXqF32Yvw?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span>
New research suggests you can't fake your emotional state to improve your work life — you have to feel it.
What is deep acting?<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNTQ1NDk2OS9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYxNTY5MzA0Nn0._s7aP25Es1CInq51pbzGrUj3GtOIRWBHZxCBFnbyXY8/img.jpg?width=1245&coordinates=333%2C-1%2C333%2C-1&height=700" id="ddf09" class="rm-shortcode" data-rm-shortcode-id="9dc42c4d6a8e372ad7b72907b46ecd3f" data-rm-shortcode-name="rebelmouse-image" data-width="1245" data-height="700" />
Arlie Russell Hochschild (pictured) laid out the concept of emotional labor in her 1983 book, "The Managed Heart."
Credit: Wikimedia Commons<p>Deep and surface acting are the principal components of emotional labor, a buzz phrase you have likely seen flitting about the Twittersphere. Today, "<a href="https://www.bbc.co.uk/bbcthree/article/5ea9f140-f722-4214-bb57-8b84f9418a7e" target="_blank">emotional labor</a>" has been adopted by groups as diverse as family counselors, academic feminists, and corporate CEOs, and each has redefined it with a patented spin. But while the phrase has splintered into a smorgasbord of pop-psychological arguments, its initial usage was more specific.</p><p>First coined by sociologist Arlie Russell Hochschild in her 1983 book, "<a href="https://www.ucpress.edu/book/9780520272941/the-managed-heart" target="_blank">The Managed Heart</a>," emotional labor describes the work we do to regulate our emotions on the job. Hochschild's go-to example is the flight attendant, who is tasked with being "nicer than natural" to enhance the customer experience. While at work, flight attendants are expected to smile and be exceedingly helpful even if they are wrestling with personal issues, the passengers are rude, and that one kid just upchucked down the center aisle. Hochschild's counterpart to the flight attendant is the bill collector, who must instead be "nastier than natural."</p><p>Such personas may serve an organization's mission or commercial interests, but if they cause emotional dissonance, they can potentially lead to high emotional costs for the employee—bringing us back to deep and surface acting.</p><p>Deep acting is the process by which people modify their emotions to match their expected role. Deep actors still encounter the negative emotions, but they devise ways to <a href="http://www.selfinjury.bctr.cornell.edu/perch/resources/what-is-emotion-regulationsinfo-brief.pdf" target="_blank">regulate those emotions</a> and return to the desired state. Flight attendants may modify their internal state by talking through harsh emotions (say, with a coworker), focusing on life's benefits (next stop Paris!), physically expressing their desired emotion (smiling and deep breaths), or recontextualizing an inauspicious situation (not the kid's fault he got sick).</p><p>Conversely, surface acting occurs when employees display ersatz emotions to match those expected by their role. These actors are the waiters who smile despite being crushed by the stress of a dinner rush. They are the CEOs who wear a confident swagger despite feelings of inauthenticity. And they are the bouncers who must maintain a steely edge despite humming show tunes in their heart of hearts.</p><p>As we'll see in the research, surface acting can degrade our mental well-being. This deterioration can be especially true of people who must contend with negative emotions or situations inside while displaying an elated mood outside. Hochschild argues such emotional labor can lead to exhaustion and self-estrangement—that is, surface actors erect a bulwark against anger, fear, and stress, but that disconnect estranges them from the emotions that allow them to connect with others and live fulfilling lives.</p>
Don't fake it till you make it<p>Most studies on emotional labor have focused on customer service for the obvious reason that such jobs prescribe emotional states—service with a smile or, if you're in the bouncing business, a scowl. But <a href="https://eller.arizona.edu/people/allison-s-gabriel" target="_blank">Allison Gabriel</a>, associate professor of management and organizations at the University of Arizona's Eller College of Management, wanted to explore how employees used emotional labor strategies in their intra-office interactions and which strategies proved most beneficial.</p><p>"What we wanted to know is whether people choose to engage in emotion regulation when interacting with their co-workers, why they choose to regulate their emotions if there is no formal rule requiring them to do so, and what benefits, if any, they get out of this effort," Gabriel said in <a href="https://www.sciencedaily.com/releases/2020/01/200117162703.htm" target="_blank">a press release</a>.</p><p>Across three studies, she and her colleagues surveyed more than 2,500 full-time employees on their emotional regulation with coworkers. The survey asked participants to agree or disagree with statements such as "I try to experience the emotions that I show to my coworkers" or "I fake a good mood when interacting with my coworkers." Other statements gauged the outcomes of such strategies—for example, "I feel emotionally drained at work." Participants were drawn from industries as varied as education, engineering, and financial services.</p><p>The results, <a href="https://psycnet.apa.org/doiLanding?doi=10.1037%2Fapl0000473" target="_blank" rel="noopener noreferrer">published in the Journal of Applied Psychology</a>, revealed four different emotional strategies. "Deep actors" engaged in high levels of deep acting; "low actors" leaned more heavily on surface acting. Meanwhile, "non-actors" engaged in negligible amounts of emotional labor, while "regulators" switched between both. The survey also revealed two drivers for such strategies: prosocial and impression management motives. The former aimed to cultivate positive relationships, the latter to present a positive front.</p><p>The researchers found deep actors were driven by prosocial motives and enjoyed advantages from their strategy of choice. These actors reported lower levels of fatigue, fewer feelings of inauthenticity, improved coworker trust, and advanced progress toward career goals. </p><p>As Gabriel told <a href="https://www.psypost.org/2021/01/new-psychology-research-suggests-deep-acting-can-reduce-fatigue-and-improve-your-work-life-59081" target="_blank" rel="noopener noreferrer">PsyPost in an interview</a>: "So, it's a win-win-win in terms of feeling good, performing well, and having positive coworker interactions."</p><p>Non-actors did not report the emotional exhaustion of their low-actor peers, but they also didn't enjoy the social gains of the deep actors. Finally, the regulators showed that the flip-flopping between surface and deep acting drained emotional reserves and strained office relationships.</p><p>"I think the 'fake it until you make it' idea suggests a survival tactic at work," Gabriel noted. "Maybe plastering on a smile to simply get out of an interaction is easier in the short run, but long term, it will undermine efforts to improve your health and the relationships you have at work. </p><p>"It all boils down to, 'Let's be nice to each other.' Not only will people feel better, but people's performance and social relationships can also improve."</p>
You'll be glad ya' decided to smile<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="88a0a6a8d1c1abfcf7b1aca8e71247c6"><iframe type="lazy-iframe" data-runner-src="https://www.youtube.com/embed/QOSgpq9EGSw?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span><p>But as with any research that relies on self-reported data, there are confounders here to untangle. Even during anonymous studies, participants may select socially acceptable answers over honest ones. They may further interpret their goal progress and coworker interactions more favorably than is accurate. And certain work conditions may not produce the same effects, such as toxic work environments or those that require employees to project negative emotions.</p><p>There also remains the question of the causal mechanism. If surface acting—or switching between surface and deep acting—is more mentally taxing than genuinely feeling an emotion, then what physiological process causes this fatigue? <a href="https://www.frontiersin.org/articles/10.3389/fnhum.2019.00151/full" target="_blank">One study published in the <em>Frontiers in Human Neuroscience</em></a><em> </em>measured hemoglobin density in participants' brains using an fNIRS while they expressed emotions facially. The researchers found no significant difference in energy consumed in the prefrontal cortex by those asked to deep act or surface act (though, this study too is limited by a lack of real-life task).<br></p><p>With that said, Gabriel's studies reinforce much of the current research on emotional labor. <a href="https://journals.sagepub.com/doi/abs/10.1177/2041386611417746" target="_blank">A 2011 meta-analysis</a> found that "discordant emotional labor states" (read: surface acting) were associated with harmful effects on well-being and performance. The analysis found no such consequences for deep acting. <a href="https://doi.apa.org/doiLanding?doi=10.1037%2Fa0022876" target="_blank" rel="noopener noreferrer">Another meta-analysis</a> found an association between surface acting and impaired well-being, job attitudes, and performance outcomes. Conversely, deep acting was associated with improved emotional performance.</p><p>So, although there's still much to learn on the emotional labor front, it seems Van Dyke's advice to a Leigh was half correct. We should put on a happy face, but it will <a href="https://bigthink.com/design-for-good/everything-you-should-know-about-happiness-in-one-infographic" target="_self">only help if we can feel it</a>.</p>
Archaeologists discover a cave painting of a wild pig that is now the world's oldest dated work of representational art.