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Study: Language (not geography) major force behind India’s gene flow
The study found that people who spoke the same language tended to be more closely related despite living far apart.

- Studies focusing on European genetics have found a strong correlation between geography and genetic variation.
- Looking toward India, a new study found a stronger correlation between gene variation and language as well as
- social structure.
- Understanding social and cultural influences can help expand our knowledge of gene flow through human history.
When we think about our ancestors, our minds tend to wander to geography. We introduce our progenitors by noting they were Norwegian, Brazilian, Indonesian, or members of an American Native tribe. Personal genetic tests, such as those offered by Ancestry and 23andMe, offer customers a travel log of their lineages' global journeys. And some of our more obvious phenotypic markers, such as hair and skin color, evolved in relationship with the lands our ancestors called home.
Lost within this land-locked focus is the fact that social and cultural factors—how our ancestors cohabitated and interacted with each other—also influence gene flow. In doing so, these factors shaped our evolution and genetic diversity. As a new study has found, for the peoples of the Indian subcontinent, such social and cultural factors may be more important to their genetic variation than the deserts, grasslands, and tropical forests between them.
A new kind of mother tongue
A map showing the locations of 33 Indian populations alongside plot graphs showing the relations between sociolinguistic groups and genetic structures.
Credit: Molecular Biology and Evolution
The new study, published in Molecular Biology and Evolution, began when Aritra Bose, who earned his doctorate at Purdue in genetics and data science, was researching the close ties between genes and geography in Europe. Originally from Calcutta, India, Bose wondered if such a strong link would be true of his home country. He teamed up with Peristera Paschou, a population geneticist and associate professor of biological sciences at Purdue University, and Petros Drineas, associate head of Purdue's Department of Computer Science, to find out.
"Our genome carries the signature of our ancestors, and the genetic structure of modern populations has been shaped by the forces of evolution. What we are looking for is what led different groups of people to come together and what drove them apart," Paschou, who led the study with Drineas, said in a press release. "To understand the genetics of human populations, we created a model that allows us to consider jointly many different factors that may have shaped genetics."
The researchers developed a computer model called COGG (Correlation Optimization of Genetics and Geodemographics) to analyze population genetic substructure. They then feed COGG a dataset featuring 981 individuals from 90 Indian groups, further merging that with a dataset of 1,323 individuals from 50 Eurasian populations. The model crunched the numbers and found something surprising.
Studies looking at European populations have typically found a strong correlation between genotype and geography. As one National Geographic writer put it when discussing a study published in Nature: "The result was startling—the genetic and geopolitical maps of Europe overlap to a remarkable degree. On the two-dimensional genetic map, you can make out Italy's boot and the Iberian peninsula [sic] where Spain and Portugal sit. The Scandinavian countries appear in the right order and in the south-east, Cyprus sits distinctly off the 'coast' of Greece."
Such a confluence of the geo and the genome was not found in the India study; in fact, the analysis showed a weak correlation between genotype and geography. Instead, it was shared language that proved the major genetic link.
The researchers found that people who speak the same language were much more likely to be closely related, regardless of where they lived on the subcontinent. For example, their analysis showed that Indo-European and Dravidian speakers shared genetic drift with Europeans, while Tibeto-Burman speaking tribes shared it with East Asians.
Social structure also showed a stronger correlation than geography in their analysis. The researchers hypothesized this correlation originated from the social stratification imposed by India's caste system.
For several thousands of years, the caste system divided Hindus into hierarchical groups based on their karma (work) and dharma (duty). Marriage was strictly limited within one's caste, resulting in a long history of endogamy. Though the caste system was effectively expunged in 1950 by the Indian government, such endogamy held sway over Indian society long enough to have a powerful effect on the country's historic gene flow.
"Our results clearly show that endogamy and language families are pivotal in studying the genetic stratification of Indian populations," the researchers write in the study.
New dimensions for understanding ancestry
None of this is to say that geography played no part in the ancestral gene flow of India, nor that social and cultural factors didn't influence genotypes across Europe. They most certainly did. That Nature study, for example, discovered genetic clusters in Switzerland that were language-based. And Europe's geographic distribution may have more to do with historical sociopolitical realities than environmental ones.
The point of both studies, however, is not to tie our genetic history to land or language, but to understand how genes flowed throughout historical societies.
"It sheds light on how genetics work in our society," Bose said in the same release. "This is the first model that can take into account social, cultural, environmental and linguistic factors that shape the gene flow of populations. It helps us to understand what factors contribute to the genetic puzzle that is India. It disentangles the puzzle."
With an improved knowledge of historic gene flow, scientists may be able to further biomedical research to better detect rare genetic variants, assess individual risks to certain diseases, and predict which populations may be more or less susceptible to particular drugs. By opening the avenues we use to understand our genetic history, we can hopefully advance such knowledge and understanding.
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Your body’s full of stuff you no longer need. Here's a list.
Evolution doesn't clean up after itself very well.
- An evolutionary biologist got people swapping ideas about our lingering vestigia.
- Basically, this is the stuff that served some evolutionary purpose at some point, but now is kind of, well, extra.
- Here are the six traits that inaugurated the fun.
The plica semilunaris
<img class="rm-lazyloadable-image rm-shortcode" type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8xOTA5NjgwMS9vcmlnaW4ucG5nIiwiZXhwaXJlc19hdCI6MTY3NDg5NTg1NX0.kdBYMvaEzvCiJjcLEPgnjII_KVtT9RMEwJFuXB68D8Q/img.png?width=980" id="59914" width="429" height="350" data-rm-shortcode-id="b11e4be64c5e1f58bf4417d8548bedc7" data-rm-shortcode-name="rebelmouse-image" />The human eye in alarming detail. Image source: Henry Gray / Wikimedia commons
<p>At the inner corner of our eyes, closest to the nasal ridge, is that little pink thing, which is probably what most of us call it, called the caruncula. Next to it is the plica semilunairs, and it's what's left of a third eyelid that used to — ready for this? — blink horizontally. It's supposed to have offered protection for our eyes, and some birds, reptiles, and fish have such a thing.</p>Palmaris longus
<img class="rm-lazyloadable-image rm-shortcode" type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8xOTA5NjgwNy9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYzMzQ1NjUwMn0.dVor41tO_NeLkGY9Tx46SwqhSVaA8HZQmQAp532xLxA/img.jpg?width=980" id="879be" width="1920" height="2560" data-rm-shortcode-id="4089a32ea9fbb1a0281db14332583ccd" data-rm-shortcode-name="rebelmouse-image" />Palmaris longus muscle. Image source: Wikimedia commons
<p> We don't have much need these days, at least most of us, to navigate from tree branch to tree branch. Still, about 86 percent of us still have the wrist muscle that used to help us do it. To see if you have it, place the back of you hand on a flat surface and touch your thumb to your pinkie. If you have a muscle that becomes visible in your wrist, that's the palmaris longus. If you don't, consider yourself more evolved (just joking).</p>Darwin's tubercle
<img class="rm-lazyloadable-image rm-shortcode" type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8xOTA5NjgxMi9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTY0ODUyNjA1MX0.8RuU-OSRf92wQpaPPJtvFreOVvicEwn39_jnbegiUOk/img.jpg?width=980" id="687a0" width="819" height="1072" data-rm-shortcode-id="ff5edf0a698e0681d11efde1d7872958" data-rm-shortcode-name="rebelmouse-image" />Darwin's tubercle. Image source: Wikimedia commons
<p> Yes, maybe the shell of you ear does feel like a dried apricot. Maybe not. But there's a ridge in that swirly structure that's a muscle which allowed us, at one point, to move our ears in the direction of interesting sounds. These days, we just turn our heads, but there it is.</p>Goosebumps
<img class="rm-lazyloadable-image rm-shortcode" type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8xOTA5NzMxNC9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYyNzEyNTc2Nn0.aVMa5fsKgiabW5vkr7BOvm2pmNKbLJF_50bwvd4aRo4/img.jpg?width=980" id="d8420" width="1440" height="960" data-rm-shortcode-id="8827e55511c8c3aed8c36d21b6541dbd" data-rm-shortcode-name="rebelmouse-image" />Goosebumps. Photo credit: Tyler Olson via Shutterstock
<p>It's not entirely clear what purpose made goosebumps worth retaining evolutionarily, but there are two circumstances in which they appear: fear and cold. For fear, they may have been a way of making body hair stand up so we'd appear larger to predators, much the way a cat's tail puffs up — numerous creatures exaggerate their size when threatened. In the cold, they may have trapped additional heat for warmth.</p>Tailbone
<img class="rm-lazyloadable-image rm-shortcode" type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8xOTA5NzMxNi9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTY3MzQwMjc3N30.nBGAfc_O9sgyK_lOUo_MHzP1vK-9kJpohLlj9ax1P8s/img.jpg?width=980" id="9a2f6" width="1440" height="1440" data-rm-shortcode-id="4fe28368d2ed6a91a4c928d4254cc02a" data-rm-shortcode-name="rebelmouse-image" />Coccyx.
Image source: Decade3d-anatomy online via Shutterstock
<p>Way back, we had tails that probably helped us balance upright, and was useful moving through trees. We still have the stump of one when we're embryos, from 4–6 weeks, and then the body mostly dissolves it during Weeks 6–8. What's left is the coccyx.</p>The palmar grasp reflex
<img class="rm-lazyloadable-image rm-shortcode" type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8xOTA5NzMyMC9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYzNjY0MDY5NX0.OSwReKLmNZkbAS12-AvRaxgCM7zyukjQUaG4vmhxTtM/img.jpg?width=980" id="8804c" width="1440" height="960" data-rm-shortcode-id="67542ee1c5a85807b0a7e63399e44575" data-rm-shortcode-name="rebelmouse-image" />Palmar reflex activated! Photo credit: Raul Luna on Flickr
<p> You've probably seen how non-human primate babies grab onto their parents' hands to be carried around. We used to do this, too. So still, if you touch your finger to a baby's palm, or if you touch the sole of their foot, the palmar grasp reflex will cause the hand or foot to try and close around your finger.</p>Other people's suggestions
<p>Amir's followers dove right in, offering both cool and questionable additions to her list. </p>Fangs?
<blockquote class="twitter-tweet" data-conversation="none" data-lang="en"><p lang="en" dir="ltr">Lower mouth plate behind your teeth. Some have protruding bone under the skin which is a throw back to large fangs. Almost like an upsidedown Sabre Tooth.</p>— neil crud (@neilcrud66) <a href="https://twitter.com/neilcrud66/status/1085606005000601600?ref_src=twsrc%5Etfw">January 16, 2019</a></blockquote> <script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>Hiccups
<blockquote class="twitter-tweet" data-conversation="none" data-lang="en"><p lang="en" dir="ltr">Sure: <a href="https://t.co/DjMZB1XidG">https://t.co/DjMZB1XidG</a></p>— Stephen Roughley (@SteBobRoughley) <a href="https://twitter.com/SteBobRoughley/status/1085529239556968448?ref_src=twsrc%5Etfw">January 16, 2019</a></blockquote> <script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>Hypnic jerk as you fall asleep
<blockquote class="twitter-tweet" data-conversation="none" data-lang="en"><p lang="en" dir="ltr">What about when you “jump” just as you’re drifting off to sleep, I heard that was a reflex to prevent falling from heights.</p>— Bann face (@thebanns) <a href="https://twitter.com/thebanns/status/1085554171879788545?ref_src=twsrc%5Etfw">January 16, 2019</a></blockquote> <script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script> <p> This thing, often called the "alpha jerk" as you drop into alpha sleep, is properly called the hypnic jerk,. It may actually be a carryover from our arboreal days. The <a href="https://www.livescience.com/39225-why-people-twitch-falling-asleep.html" target="_blank" data-vivaldi-spatnav-clickable="1">hypothesis</a> is that you suddenly jerk awake to avoid falling out of your tree.</p>Nails screeching on a blackboard response?
<blockquote class="twitter-tweet" data-conversation="none" data-lang="en"><p lang="en" dir="ltr">Everyone hate the sound of fingernails on a blackboard. It's _speculated_ that this is a vestigial wiring in our head, because the sound is similar to the shrill warning call of a chimp. <a href="https://t.co/ReyZBy6XNN">https://t.co/ReyZBy6XNN</a></p>— Pet Rock (@eclogiter) <a href="https://twitter.com/eclogiter/status/1085587006258888706?ref_src=twsrc%5Etfw">January 16, 2019</a></blockquote> <script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>Ear hair
<blockquote class="twitter-tweet" data-conversation="none" data-lang="en"><p lang="en" dir="ltr">Ok what is Hair in the ears for? I think cuz as we get older it filters out the BS.</p>— Sarah21 (@mimix3) <a href="https://twitter.com/mimix3/status/1085684393593561088?ref_src=twsrc%5Etfw">January 16, 2019</a></blockquote> <script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>Nervous laughter
<blockquote class="twitter-tweet" data-lang="en"><p lang="en" dir="ltr">You may be onto something. Tooth-bearing with the jaw clenched is generally recognized as a signal of submission or non-threatening in primates. Involuntary smiling or laughing in tense situations might have signaled that you weren’t a threat.</p>— Jager Tusk (@JagerTusk) <a href="https://twitter.com/JagerTusk/status/1085316201104912384?ref_src=twsrc%5Etfw">January 15, 2019</a></blockquote> <script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>Um, yipes.
<blockquote class="twitter-tweet" data-conversation="none" data-lang="en"><p lang="en" dir="ltr">Sometimes it feels like my big toe should be on the side of my foot, was that ever a thing?</p>— B033? K@($ (@whimbrel17) <a href="https://twitter.com/whimbrel17/status/1085559016011563009?ref_src=twsrc%5Etfw">January 16, 2019</a></blockquote> <script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>The COVID-19 pandemic has introduced a number of new behaviours into daily routines, like physical distancing, mask-wearing and hand sanitizing. Meanwhile, many old behaviours such as attending events, eating out and seeing friends have been put on hold.
VR experiments manipulate how people feel about coffee
A new study looks at how images of coffee's origins affect the perception of its premiumness and quality.
Expert drinking coffee while wearing a VR headset.
- Images can affect how people perceive the quality of a product.
- In a new study, researchers show using virtual reality that images of farms positively influence the subjects' experience of coffee.
- The results provide insights on the psychology and power of marketing.
Is empathy always good?
Research has shown how important empathy is to relationships, but there are limits to its power.
