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US, Russia, China won't join global initiative to offer fair access to COVID-19 vaccines. Why not?
The U.S., China, and Russia are in a "vaccine race" that treats a global challenge like a winner-take-all game.
The board game "Pandemic" tasks players with stopping deadly diseases as they spread across the world. But what separates "Pandemic" from its winner-take-all peers is that it's a collaborative endeavor. Players either pull together to stamp out their microscopic foes, or they all lose.
Commentators have naturally drawn comparisons between the game and the COVID era it has become emblematic of, and those parallels have become more fitting lately. On September 21, the World Health Organization (WHO) announced that 156 countries had joined the COVAX Facility, a worldwide collaboration to develop a vaccine and distribute it strategically and equitably.
But as any "Pandemic" fan will tell you, there are always those players: the ones who cut ties with the others, who play to be the most powerful, who reinterpret the goal as domination in a zero-sum game of their own devising. Unfortunately for WHO and its allies, three big global players have refused to play cooperatively: China, Russia, and the United States.
All for one (vaccine)
Launched this April, the Access to COVID-19 Tools (ACT) Accelerator brought together a panoply of governments, scientists, businesses, and global health organizations with the goal of accelerating the development, production, and distribution of an efficacious COVID-19 vaccine. The "vaccines pillar" of this initiative is the COVAX Facility.
COVAX is coordinated by the WHO, the Coalition for Epidemic Preparedness Innovations (CEPI), and Gavi, the Vaccine Alliance. The program maintains a diverse portfolio of COVID-10 vaccines, monitoring each to identify promising candidates. It has also partnered with manufacturers to ease investment risks and serves as a purchasing pool for self-financing countries, while offering fundraising efforts to poorer ones.
"[G]overnments from every continent have chosen to work together, not only to secure vaccines for their own populations, but also to help ensure that vaccines are available to the most vulnerable everywhere," Seth Berkley, CEO of Gavi, said in a release. "With the commitments we're announcing today for the COVAX Facility, as well as the historic partnership we are forging with industry, we now stand a far better chance of ending the acute phase of this pandemic once safe, effective vaccines become available."
In an interview with Vox, Berkley noted that the ACT Accelerator is the largest global collaboration since the Paris Climate Agreement. He added, "This type of solidarity is critical because otherwise what you're going to end up with is just a constant reintroduction of infections and the inability to go back to normal."
As of Monday, 64 higher-income countries and 92 low- and middle-income countries—representing nearly two-thirds of the world's population—have signed commitments to COVAX. Thirty-eight more are expected to sign soon.
COVAX's goal is to have 2 billion doses by the end of 2021. Experts estimate this amount will cover high-risk and vulnerable people, as well as healthcare workers, worldwide. Participating nations must cover those populations before administering vaccines according to national priorities. As part of the agreement, countries agree to support equal access to the vaccine once it becomes available, a move aimed at preventing hoarding and price gouging.
Currently, CEPI is supporting nine candidate vaccines, of which eight are in clinical trials.
Why has the U.S. backed out?
The United States is gambling that its bilateral deals with various pharmaceutical companies will win the "vaccine race." This U.S.-only initiative, named (sigh) Operation Warp Speed, has already spent approximately $10 billion and is pushing to deliver 300 million doses by January 2021. Many experts worry this speedy push through the regulatory path could result in premature and dangerous approvals.
China and Russia have likewise bet on their own high-priced ponies. Russia is touting an unvetted vaccine nicknamed (double sigh) "Sputnik V." This vaccine has only concluded phase 1 and 2 trials with a small number of participants, yet Russia claims to have already received international requests. Meanwhile, China has administered tens of thousands of doses of a vaccine before completing phase 3 clinical trials.
An additional barrier to the United States' participation: COVAX is a WHO-led initiative. Earlier this year, President Donald Trump admonished the WHO as a corrupt organization and claimed it assisted China in covering up the coronavirus outbreak and its severity. Though he presented no evidence for the accusation, Trump has used it as the basis for his threat to cut ties with, and funding for, the agency.
"The United States will continue to engage our international partners to ensure we defeat this virus, but we will not be constrained by multilateral organizations influenced by the corrupt World Health Organization and China," said Judd Deere, a spokesman for the White House, said in a statement.
He added, "This president will spare no expense to ensure that any new vaccine maintains our own FDA's gold standard for safety and efficacy, is thoroughly tested, and saves lives."
By shirking COVAX, these countries hope to gain peerless access to a vaccine. Each could secure large numbers of doses for its citizens while also reaping the political boons to follow. In the United States, President Trump has pinned his re-election bid on a timely vaccine, while Chinese officials seem posed to use a vaccine to repair diplomatic ties.
But the loss of such rich economies will prove a blow to COVAX and the ACT Accelerator. Vaccines are notoriously expensive and risky to develop; the costs to manufacture doses at scale will be immense. WHO Director-General Tedros Adhanom Ghebreyesus stated the ACT Accelerator would cost roughly $30 billion, and the final bill for the tools to combat novel coronavirus would be at least $100 billion. But that's a pittance compared to the $10 trillion already spent on the pandemic so far.
"COVID-19 is an unprecedented global crisis that demands an unprecedented global response," Tedros said. "Vaccine nationalism will only perpetuate the disease and prolong the global recovery. Working together through the COVAX Facility is not charity, it's in every country's own best interests to control the pandemic and accelerate the global economic recovery."
The winner won't necessarily take all
By COVAX's count, there are 170 COVID-19 vaccines in development. None have been approved, few have reached phase 3, and most will fail to exit clinical trials. While one or two may be ready by year's end, they probably won't be a corona-cure-all. They will likely be similar to flu vaccines, reducing the contraction risk and the severity of symptoms.
"We all recognize that flu vaccine, in a year when it's efficacious, you have what, 50% protection? And in a year when it's poor you have 30% or less than that—and still we use that," Marie-Paule Kieny, WHO assistant director-general of Health Systems and Innovation, told Stat.
That means any country to pass the approval finish line won't necessarily win it all. After approval, it will still take a global effort to manufacture and distribute doses. Without blanketed protection, even countries with a high inoculation rate will risk reintroduction of the virus from those still struggling to contain it.
As any player of "Pandemic" will tell you, when a player decides to go it alone, they don't just make the game more difficult. They diminish the trust and cooperation for many games to come.
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The team caught a glimpse of a process that takes 18,000,000,000,000,000,000,000 years.
- In Italy, a team of scientists is using a highly sophisticated detector to hunt for dark matter.
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Humans are particularly prone to shiver when a group does or thinks the same thing at the same time.
A few years ago, I proposed that the feeling of cold in one's spine, while for example watching a film or listening to music, corresponds to an event when our vital need for cognition is satisfied.
Certain colors are globally linked to certain feelings, the study reveals.
- Color psychology is often used in marketing to alter your perception of products and services.
- Various studies and experiments across multiple years have given us more insight into the link between personality and color.
- The results of a new study spanning 6 continents (30 nations) shows universal correlations between colors and emotions around the globe.
The root of color psychology<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="9e40cf62fa8922fcca6c57e2fcb215b6"><iframe type="lazy-iframe" data-runner-src="https://www.youtube.com/embed/OM4fXB23pCQ?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span><p>There is a very likely chance you've even been "fooled" by color marketing in the past, or you've chosen one product over another subconsciously due to colors that were designed to influence your emotions.<br></p><p>Companies that want to be known for being dependable often use blue in their logos, for example (Dell, HP, IBM). Companies that want to be perceived as fun and exciting go for a splash of orange (Fanta, Nickelodeon, even Amazon). Green is associated with natural, peaceful emotions and is often used by companies like Whole Foods and Tropicana. </p><p><strong>Your favorite color says a lot about your personality. </strong></p><p>Various studies and experiments across multiple years (<a href="https://www.researchgate.net/publication/49595886_Personality_Traits_and_Colour_Preferences" target="_blank">2010</a>, <a href="https://onlinelibrary.wiley.com/doi/abs/10.1111/jopy.12087" target="_blank" rel="noopener noreferrer">2014</a>, <a href="http://oaji.net/articles/2015/1170-1448038739.pdf" target="_blank" rel="noopener noreferrer">2015</a>, and more recently in <a href="https://www.verywellmind.com/color-psychology-2795824#modern-research-on-color-psychology" target="_blank" rel="noopener noreferrer">2019</a>) have given us more insight into the link between your personality and your favorite color.</p><p>Red, for example, is considered a bold color and is associated with feelings such as excitement, passion, anger, danger, energy, and love. The personality traits of this color might be someone who is bold, a little impulsive, and who loves adventure. </p><p>Orange, on the other hand, is considered representative of creativity, happiness, and freedom. The personality traits of this color can be fun, playful, cheerful, nurturing, and productive. Read more about color psychology and personalities <a href="https://bigthink.com/mind-brain/color-personality-psychology?rebelltitem=2#rebelltitem2" target="_self">here</a>.</p>
Study reveals which colors best suit which emotions around the globe<img type="lazy-image" data-runner-src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yNDYzMTk5OS9vcmlnaW4uanBnIiwiZXhwaXJlc19hdCI6MTYyODc4OTg5OH0.bY-pu-MFNivdJLDJuBp9TBKrhwuy7hngUa1aIWxQMVw/img.jpg?width=1245&coordinates=0%2C93%2C0%2C94&height=700" id="33fff" class="rm-shortcode" data-rm-shortcode-id="1a5d7bb00dac94bd6201616789fb4882" data-rm-shortcode-name="rebelmouse-image" alt="concept of color psychology how colors make us feel color emotions" />
Certain colors are globally ties to certain emotions, the study reveals.
Image by agsandrew on Shutterstock<p>In this particular survey, participants were asked to fill out an online questionnaire which involved assigning 20 emotions to 12 different color terms. They were also asked to specify the intensity with which they associated the color term with the emotion.</p><p><strong>Certain colors are globally linked to certain emotions, the study reveals.</strong></p><p>The results of this study showed a few definite correlations between colors and emotions throughout the globe. Red, for example, is the only color that is strongly associated with both negative (anger) and positive (love) feelings. Brown, on the other end of the spectrum, is the color that triggers the fewest emotions globally.<br></p><p>The color white is closely associated with sadness in China, while purple is what is closely associated with sadness in Greece. This can be traced back to the roots of each culture, with white being worn at funerals in China and dark purple being the Greek Orthodox Church's color of mourning. </p><p>Yellow is more associated with joy, specifically in countries that see less sunshine. Meanwhile, its association with joy is weaker in areas that have greater exposure to sunshine. </p><p><a href="https://www.sciencedaily.com/releases/2020/09/200910150247.htm" target="_blank">According to Dr. Oberfeld-Twistel</a>, it is difficult to say exactly what the causes for global similarities and differences are. "There is a range of possible influencing factors: language, culture, religion, climate, the history of human development, the human perceptual system."</p>