In my view the threat of the weaponized recombinant virus is the single greatest threat facing humanity. Yes, I'm very much concerned about Global Warming, nuclear weapons, deforestation, inequities in wealth, political and religious extremism, and many other issues, but nothing else threatens to kill us with such inexorable certainty. I don't wish to saturate the valuable bandwidth of Big Think, but I have set out my ideas in two essays on the Scientist Errant website, accessible via the following links: Hoping for your survival, Michael J. Corey The Scientist Errant