Philanthropy can't fix everything at once so start with the basics, like clean water and major public health problems, to improve quality of lives for the largest numbers of people. For the long term education and employment are key, so all children need universal free education. Whatever the focus of philanthropy it is important to use 'evidence based' judgments to prioritize and measure effectiveness. Overwhelming needs? - team up with others to provide complementary assistance and avoid duplication of effort and make sure intervention responds to local priorities and demands rather than imposing an outside 'solution'. Strive to deliver assistance equitably based on needs not politics/religion to avoid creating/amplifying resentment. Think appropriate, sustainable, development that uses local talents and resources. Train local people to lead, develop and maintain projects.