Why Can't The GOP Get Behind Mitt Romney?
What is wrong with Mitt Romney? Why is the Republican Party wasting its time looking under every rock in Creation (pun intended) for someone who is just about guaranteed to be less intelligent and less accomplished than the former Massachusetts governor? Why are conservative bloggers who are still pining for a Chris Christie candidacy allowed to get within ten feet of a keyboard without supervision? Is it possible that the GOP, in its nonsensical quest for a chest beating fire breathing bona fide conservative who is willing to shut the entire federal government down if necessary and throw away the key, is ignoring the best chance they have to regain the White House in 2012?
I am beginning to like Mitt Romney more and more with each Republican debate, which is a mouthful for someone who often thinks the GOP should be given a time machine so they could zap themselves back to the Constitutional Convention. In fact, Romney’s political reasonableness isn’t all that different from the political reasonableness of our current Democratic president. Aside from a tendency to rail on about how he would deal with “Obamacare” and a penchant for the “Obama is a failure” phrase that is aimed squarely at the more hardcore constituents of the Republican Party, the former Massachusetts governor’s firm grasp of today’s political realities unquestionably separates him from the riffraff that comprises the rest of the slate of GOP presidential hopefuls.
The worst thing about our media’s insistence on trying to score presidential debates like boxing matches is the inordinate amount of emphasis placed on how well a candidate hurls verbal bon mots at his opponents while he stands on a TV soundstage. I don’t know whose idea it was to put together this marathon of back to back to back to back to back debates, but if they figured all of this TV time would put President Obama at a disadvantage, they were wrong.
The public has gotten more than a little tired of the weekly broadcast of the same old talking points. Many of the candidates—actually, now that I think of it, all of them except Romney—have taken their turn as the viral video joke of the week around the web because of some of their more extremist rhetoric. And some of the members of the audiences for these debates have loudly demonstrated over the last two weeks that they are sorely deficient in the human decency department.
They say timing is everything. All those years the Republican Party has toiled to cultivate lockstep close-mindedness amongst their followers has resulted in a bumper crop of intolerant right wing conservative voters just when America’s shifting demographics make it almost impossible, under our current electoral system, to elect another George Bush. I think the real reason the GOP faithful can’t get excited about Romney is because they know he will make the Republican Party’s bible thumpers and militia minded maniacs go to the back of the bus if he gets behind the wheel.
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A new method promises to capture an elusive dark world particle.
- Scientists working on the Large Hadron Collider (LHC) devised a method for trapping dark matter particles.
- Dark matter is estimated to take up 26.8% of all matter in the Universe.
- The researchers will be able to try their approach in 2021, when the LHC goes back online.
Researchers hope the technology will further our understanding of the brain, but lawmakers may not be ready for the ethical challenges.
- Researchers at the Yale School of Medicine successfully restored some functions to pig brains that had been dead for hours.
- They hope the technology will advance our understanding of the brain, potentially developing new treatments for debilitating diseases and disorders.
- The research raises many ethical questions and puts to the test our current understanding of death.
The image of an undead brain coming back to live again is the stuff of science fiction. Not just any science fiction, specifically B-grade sci fi. What instantly springs to mind is the black-and-white horrors of films like Fiend Without a Face. Bad acting. Plastic monstrosities. Visible strings. And a spinal cord that, for some reason, is also a tentacle?
But like any good science fiction, it's only a matter of time before some manner of it seeps into our reality. This week's Nature published the findings of researchers who managed to restore function to pigs' brains that were clinically dead. At least, what we once thought of as dead.
What's dead may never die, it seems
The researchers did not hail from House Greyjoy — "What is dead may never die" — but came largely from the Yale School of Medicine. They connected 32 pig brains to a system called BrainEx. BrainEx is an artificial perfusion system — that is, a system that takes over the functions normally regulated by the organ. The pigs had been killed four hours earlier at a U.S. Department of Agriculture slaughterhouse; their brains completely removed from the skulls.
BrainEx pumped an experiment solution into the brain that essentially mimic blood flow. It brought oxygen and nutrients to the tissues, giving brain cells the resources to begin many normal functions. The cells began consuming and metabolizing sugars. The brains' immune systems kicked in. Neuron samples could carry an electrical signal. Some brain cells even responded to drugs.
The researchers have managed to keep some brains alive for up to 36 hours, and currently do not know if BrainEx can have sustained the brains longer. "It is conceivable we are just preventing the inevitable, and the brain won't be able to recover," said Nenad Sestan, Yale neuroscientist and the lead researcher.
As a control, other brains received either a fake solution or no solution at all. None revived brain activity and deteriorated as normal.
The researchers hope the technology can enhance our ability to study the brain and its cellular functions. One of the main avenues of such studies would be brain disorders and diseases. This could point the way to developing new of treatments for the likes of brain injuries, Alzheimer's, Huntington's, and neurodegenerative conditions.
"This is an extraordinary and very promising breakthrough for neuroscience. It immediately offers a much better model for studying the human brain, which is extraordinarily important, given the vast amount of human suffering from diseases of the mind [and] brain," Nita Farahany, the bioethicists at the Duke University School of Law who wrote the study's commentary, told National Geographic.
An ethical gray matter
Before anyone gets an Island of Dr. Moreau vibe, it's worth noting that the brains did not approach neural activity anywhere near consciousness.
The BrainEx solution contained chemicals that prevented neurons from firing. To be extra cautious, the researchers also monitored the brains for any such activity and were prepared to administer an anesthetic should they have seen signs of consciousness.
Even so, the research signals a massive debate to come regarding medical ethics and our definition of death.
Most countries define death, clinically speaking, as the irreversible loss of brain or circulatory function. This definition was already at odds with some folk- and value-centric understandings, but where do we go if it becomes possible to reverse clinical death with artificial perfusion?
"This is wild," Jonathan Moreno, a bioethicist at the University of Pennsylvania, told the New York Times. "If ever there was an issue that merited big public deliberation on the ethics of science and medicine, this is one."
One possible consequence involves organ donations. Some European countries require emergency responders to use a process that preserves organs when they cannot resuscitate a person. They continue to pump blood throughout the body, but use a "thoracic aortic occlusion balloon" to prevent that blood from reaching the brain.
The system is already controversial because it raises concerns about what caused the patient's death. But what happens when brain death becomes readily reversible? Stuart Younger, a bioethicist at Case Western Reserve University, told Nature that if BrainEx were to become widely available, it could shrink the pool of eligible donors.
"There's a potential conflict here between the interests of potential donors — who might not even be donors — and people who are waiting for organs," he said.
It will be a while before such experiments go anywhere near human subjects. A more immediate ethical question relates to how such experiments harm animal subjects.
Ethical review boards evaluate research protocols and can reject any that causes undue pain, suffering, or distress. Since dead animals feel no pain, suffer no trauma, they are typically approved as subjects. But how do such boards make a judgement regarding the suffering of a "cellularly active" brain? The distress of a partially alive brain?
The dilemma is unprecedented.
Setting new boundaries
Another science fiction story that comes to mind when discussing this story is, of course, Frankenstein. As Farahany told National Geographic: "It is definitely has [sic] a good science-fiction element to it, and it is restoring cellular function where we previously thought impossible. But to have Frankenstein, you need some degree of consciousness, some 'there' there. [The researchers] did not recover any form of consciousness in this study, and it is still unclear if we ever could. But we are one step closer to that possibility."
She's right. The researchers undertook their research for the betterment of humanity, and we may one day reap some unimaginable medical benefits from it. The ethical questions, however, remain as unsettling as the stories they remind us of.
- As a stand-up comedian, Pete Holmes knows how words can manipulate audiences — for good and bad.
- Words aren't just words. They stich together our social fabric, helping establish and maintain relationships.
- Holmes has a clever linguistic exercise meant to bring you closer to the people around you.
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