Philosophy has always had the goal of simplifying knowledge, that is to say, reducing our understanding of the universe to a single unifying theory.
The more progress that we make in science however, the more we realize what we don't know. In his critique of Super String Theory, Dartmouth professor Marcelo Gleiser uses the helpful metaphor of an island. Knowledge is an island that is constantly growing. The more it grows, the larger the border around it grows.
So the history of knwoledge will always be incomplete, Gleiser argues.