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We live in a time of information abundance, which far too many of us see as information overload. With the sum total of human knowledge, past and present, at our fingertips, we’re faced with a crisis of attention: which ideas should we engage with, and why? Big Think is an evolving roadmap to the best thinking on the planet — the ideas that can help you think flexibly and act decisively in a multivariate world.

A word about Big Ideas and Themes — The architecture of Big Think

Big ideas are lenses for envisioning the future. Every article and video on bigthink.com and on our learning platforms is based on an emerging “big idea” that is significant, widely relevant, and actionable. We’re sifting the noise for the questions and insights that have the power to change all of our lives, for decades to come. For example, reverse-engineering is a big idea in that the concept is increasingly useful across multiple disciplines, from education to nanotechnology.

Themes are the seven broad umbrellas under which we organize the hundreds of big ideas that populate Big Think. They include New World Order, Earth and Beyond, 21st Century Living, Going Mental, Extreme Biology, Power and Influence, and Inventing the Future.

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Big Think’s contributors offer expert analysis of the big ideas behind the news.

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Severe Risk

January 8, 2010, 6:06 AM
New research has found that there is an increased presence and severity of coronary artery plaques in men infected with HIV. “A Massachusetts General Hospital (MGH) study has found that relatively young men with longstanding HIV infection and minimal cardiac risk factors had significantly more coronary atherosclerotic plaques -- some involving serious arterial blockage -- than did uninfected men with similar cardiovascular risk. The investigation appearing in the January 2010 issue of the journal AIDS is the first to use CT angiography to identify coronary artery plaques in HIV-infected participants. ‘We were particularly surprised to find that several of the HIV patients -- none of whom had symptoms of heart disease -- had obstructive coronary artery disease, which was found in none of the controls,’ says Janet Lo, MD, of the Program in Nutritional Metabolism in the MGH Department of Medicine, who led the study. ‘It appears that both traditional and nontraditional risk factors are contributing to atherosclerotic disease in HIV-infected patients.’”
 

Severe Risk

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