Dr. John Ioannidis' claim, that up to 90 percent of published medical research is flawed, has yielded valuable insight into the controversial methods of the research industry. "Research is expensive and scientists fund it by competing for grants that provide funding for two to three years. Research productivity is measured in terms of numbers and quality of research papers published. The most prestigious journals reject up to 90 per cent of papers submitted to them. A successful scientific career depends on regularly winning research grants and publishing papers in prestigious journals. This is a high-pressure game studded with temptations to cut corners."